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Showing 25 to 36 of 182 entries
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Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines-A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters.

Viruses

Trimpert J, Herwig S, Stein J, Vladimirova D, Adler JM, Abdelgawad A, Firsching TC, Thoma T, Sehouli J, Osterrieder K, Gruber AD, Sawitzki B, Sander LE, Cichon G.
PMID: 34835096
Viruses. 2021 Nov 16;13(11). doi: 10.3390/v13112290.

With the exception of inactivated vaccines, all SARS-CoV-2 vaccines currently used for clinical application focus on the spike envelope glycoprotein as a virus-specific antigen. Compared to other SARS-CoV-2 genes, mutations in the spike protein gene are more rapidly selected...

Myelomeningocele-Chiari II malformation-Neurological predictability based on fetal and postnatal magnetic resonance imaging.

Prenatal diagnosis

Khalaveh F, Seidl R, Czech T, Reinprecht A, Gruber GM, Berger A, Kiss H, Prayer D, Kasprian G.
PMID: 34124788
Prenat Diagn. 2021 Jul;41(8):922-932. doi: 10.1002/pd.5987. Epub 2021 Jun 19.

OBJECTIVE: This systematic comparison between pre- and postnatal imaging findings and postnatal motor outcome assesses the reliability of MRI accuracy in the prognostication of the future long-term (mean, 11.4 years) ambulatory status in a historic group of postnatally repaired...

Resonant Optical Antennas with Atomic-Sized Tips and Tunable Gaps Achieved by Mechanical Actuation and Electrical Control.

Nano letters

Gruber CM, Herrmann L, Bellido EP, Dössegger J, Olziersky A, Drechsler U, Puebla-Hellmann G, Botton GA, Novotny L, Lörtscher E.
PMID: 32369701
Nano Lett. 2020 Jun 10;20(6):4346-4353. doi: 10.1021/acs.nanolett.0c01072. Epub 2020 May 12.

Enhanced electromagnetic fields in nanometer gaps of plasmonic structures increase the optical interaction with matter, including Raman scattering and optical absorption. Quantum electron tunneling across sub-1 nm gaps, however, lowers these effects again. Understanding these phenomena requires controlled variation...

Patellar Tendon Length is Associated with Lower Extremity Length but Not Gender.

Indian journal of orthopaedics

Hohenberger GM, Dreu M, Kreuzthaler H, Gruber G, Riedl R, Schwarz A, Vielgut I, Widhalm H, Sadoghi P.
PMID: 32399156
Indian J Orthop. 2020 Jan 31;54(3):352-357. doi: 10.1007/s43465-020-00046-1. eCollection 2020 May.

BACKGROUND: The aim of this study was to evaluate the patellar tendon length (PTL) with focus on gender differences and possible correlations with the total leg length (TLL) and the long bones of the lower extremity.MATERIALS AND METHODS: The...

New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer.

British journal of cancer

Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger H, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Blanc-Onfroy ML, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McReady D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph D, Tobias JS.
PMID: 34035435
Br J Cancer. 2021 Aug;125(3):380-389. doi: 10.1038/s41416-021-01440-8. Epub 2021 May 25.

BACKGROUND: The TARGIT-A trial reported risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy for breast cancer to be as effective as whole-breast external beam radiotherapy (EBRT). Here, we present further detailed analyses.METHODS: In total, 2298 women (≥45 years, invasive ductal...

Tailored axillary surgery in patients with clinically node-positive breast cancer: Pre-planned feasibility substudy of TAXIS (OPBC-03, SAKK 23/16, IBCSG 57-18, ABCSG-53, GBG 101).

Breast (Edinburgh, Scotland)

Weber WP, Matrai Z, Hayoz S, Tausch C, Henke G, Zwahlen DR, Gruber G, Zimmermann F, Seiler S, Maddox C, Ruhstaller T, Muenst S, Ackerknecht M, Kuemmel S, Bjelic-Radisic V, Kurzeder C, Újhelyi M, Vrieling C, Satler R, Meyer I, Becciolini C, Bucher S, Simonson C, Fehr PM, Gabriel N, Maráz R, Sarlos D, Dedes KJ, Leo C, Berclaz G, Dubsky P, Exner R, Fansa H, Hager C, Reisenberger K, Singer CF, Reitsamer R, Reinisch M, Winkler J, Lam GT, Fehr MK, Naydina T, Kohlik M, Clerc K, Ostapenko V, Fitzal F, Nussbaumer R, Maggi N, Schulz A, Markellou P, Lelièvre L, Egle D, Heil J, Knauer M.
PMID: 34555676
Breast. 2021 Dec;60:98-110. doi: 10.1016/j.breast.2021.09.004. Epub 2021 Sep 08.

AIM: We developed tailored axillary surgery (TAS) to reduce the axillary tumor volume in patients with clinically node-positive breast cancer to the point where radiotherapy can control it. The aim of this study was to quantify the extent of...

Beetroot supplementation in women enjoying exercise together (BEE SWEET): Rationale, design and methods.

Contemporary clinical trials communications

Baranauskas MN, Altherr CA, Gruber AH, Coggan AR, Raglin JS, Gupta SK, Carter SJ.
PMID: 33392416
Contemp Clin Trials Commun. 2020 Dec 25;21:100693. doi: 10.1016/j.conctc.2020.100693. eCollection 2021 Mar.

BACKGROUND: Postmenopausal women exhibit higher rates of disability and cardiovascular disease (CVD) with aging compared to men. Whereas habitual exercise training is a known strategy to enhance physiologic function in men and premenopausal women, exercise-related adaptations are often modest...

Improved neurodevelopmental prognostication in isolated corpus callosal agenesis: fetal magnetic resonance imaging-based scoring system.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

Diogo MC, Glatter S, Prayer D, Gruber GM, Bettelheim D, Weber M, Dovjak G, Seidl R, Kasprian G.
PMID: 32484578
Ultrasound Obstet Gynecol. 2021 Jul;58(1):34-41. doi: 10.1002/uog.22102.

OBJECTIVES: Corpus callosal agenesis (CCA) is one of the most common brain malformations and is generally associated with a good outcome when isolated. However, up to 25% of patients are at risk of neurodevelopmental delay, which currently available clinical...

3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Pogledic I, Schwartz E, Bobić-Rasonja M, Mitter C, Baltzer P, Gruber GM, Milković-Periša M, Haberler C, Bettelheim D, Kasprian G, Judaš M, Prayer D, Jovanov-Milošević N.
PMID: 34653829
Eur J Paediatr Neurol. 2021 Nov;35:67-73. doi: 10.1016/j.ejpn.2021.09.014. Epub 2021 Oct 09.

In this study we compare temporal lobe (TL) signal intensity (SI) profiles, along with the average thicknesses of the transient zones obtained from postmortem MRI (pMRI) scans and corresponding histological slices, to the frontal lobe (FL) SI and zone...

Cutaneous form of maculopapular mastocytosis in a foal.

Veterinary dermatology

Junginger J, Geburek F, Khan MA, Müller G, Gruber AD, Hewicker-Trautwein M.
PMID: 27109586
Vet Dermatol. 2016 Jun;27(3):202-e51. doi: 10.1111/vde.12308. Epub 2016 Apr 24.

BACKGROUND: Cutaneous mastocytosis is a rare benign disease occurring in domestic animals and humans. In previous reports, dermal findings in foals were accompanied by systemic mast cell infiltrations, whereas lesions in human cutaneous mastocytosis, including urticaria pigmentosa and solitary...

Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders.

Neuroscience and biobehavioral reviews

Matisz CE, Gruber AJ.
PMID: 34929227
Neurosci Biobehav Rev. 2021 Dec 17;133:104497. doi: 10.1016/j.neubiorev.2021.12.020. Epub 2021 Dec 17.

Most gastrointestinal diseases and disorders (GIDD) are associated with depression, anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly chronic pain and inflammation, affect specific neural targets. The critical review of clinical and animal research presented...

Exploiting Fluorescence Lifetime Plasticity in FLIM: Target Molecule Localization in Cells and Tissues.

ACS medicinal chemistry letters

Boreham A, Kim TY, Spahn V, Stein C, Mundhenk L, Gruber AD, Haag R, Welker P, Licha K, Alexiev U.
PMID: 24900259
ACS Med Chem Lett. 2011 Aug 09;2(10):724-8. doi: 10.1021/ml200092m. eCollection 2011 Oct 13.

The mechanisms of drug-receptor interactions and the controlled delivery of drugs via biodegradable and biocompatible nanoparticulate carriers are active research fields in nanomedicine. Many clinically used drugs target G-protein coupled receptors (GPCRs) due to the fact that signaling via...

Showing 25 to 36 of 182 entries