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Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality.

Proceedings of the National Academy of Sciences of the United States of America

Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC.
PMID: 28794281
Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9164-9169. doi: 10.1073/pnas.1707466114. Epub 2017 Aug 09.

Downstream metabolic events can contribute to the lethality of drugs or agents that interact with a primary cellular target. In bacteria, the production of reactive oxygen species (ROS) has been associated with the lethal effects of a variety of...

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Takahashi N, Gruber CC, Yang JH, et al. Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proc Natl Acad Sci U S A. 2017;114(34):9164-9169doi: 10.1073/pnas.1707466114.
Takahashi, N., Gruber, C. C., Yang, J. H., Liu, X., Braff, D., Yashaswini, C. N., Bhubhanil, S., Furuta, Y., Andreescu, S., Collins, J. J., & Walker, G. C. (2017). Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proceedings of the National Academy of Sciences of the United States of America, 114(34), 9164-9169. https://doi.org/10.1073/pnas.1707466114
Takahashi, Noriko, et al. "Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality." Proceedings of the National Academy of Sciences of the United States of America vol. 114,34 (2017): 9164-9169. doi: https://doi.org/10.1073/pnas.1707466114
Takahashi N, Gruber CC, Yang JH, Liu X, Braff D, Yashaswini CN, Bhubhanil S, Furuta Y, Andreescu S, Collins JJ, Walker GC. Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9164-9169. doi: 10.1073/pnas.1707466114. Epub 2017 Aug 09. PMID: 28794281; PMCID: PMC5576823.
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Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins.

Frontiers in chemistry

Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kümmel D, Göransson U, Becker CW, Gruber CW.
PMID: 29075625
Front Chem. 2017 Oct 11;5:73. doi: 10.3389/fchem.2017.00073. eCollection 2017.

Target deconvolution is one of the most challenging tasks in drug discovery, but a key step in drug development. In contrast to small molecules, there is a lack of validated and robust methodologies for target elucidation of peptides. In...

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Hellinger R, Thell K, Vasileva M, et al. Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Front Chem. 2017;5:73doi: 10.3389/fchem.2017.00073.
Hellinger, R., Thell, K., Vasileva, M., Muhammad, T., Gunasekera, S., Kümmel, D., Göransson, U., Becker, C. W., & Gruber, C. W. (2017). Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Frontiers in chemistry, 573. https://doi.org/10.3389/fchem.2017.00073
Hellinger, Roland, et al. "Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins." Frontiers in chemistry vol. 5 (2017): 73. doi: https://doi.org/10.3389/fchem.2017.00073
Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kümmel D, Göransson U, Becker CW, Gruber CW. Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Front Chem. 2017 Oct 11;5:73. doi: 10.3389/fchem.2017.00073. eCollection 2017. PMID: 29075625; PMCID: PMC5641551.
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Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load.

Frontiers in integrative neuroscience

Ivan VE, Banks PJ, Goodfellow K, Gruber AJ.
PMID: 29568264
Front Integr Neurosci. 2018 Mar 08;12:9. doi: 10.3389/fnint.2018.00009. eCollection 2018.

The propensity of animals to shift choices immediately after unexpectedly poor reinforcement outcomes is a pervasive strategy across species and tasks. We report here on the memory supporting such lose-shift responding in humans, assessed using a binary choice task...

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Ivan VE, Banks PJ, Goodfellow K, et al. Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load. Front Integr Neurosci. 2018;12:9doi: 10.3389/fnint.2018.00009.
Ivan, V. E., Banks, P. J., Goodfellow, K., & Gruber, A. J. (2018). Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load. Frontiers in integrative neuroscience, 129. https://doi.org/10.3389/fnint.2018.00009
Ivan, Victorita E, et al. "Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load." Frontiers in integrative neuroscience vol. 12 (2018): 9. doi: https://doi.org/10.3389/fnint.2018.00009
Ivan VE, Banks PJ, Goodfellow K, Gruber AJ. Lose-Shift Responding in Humans Is Promoted by Increased Cognitive Load. Front Integr Neurosci. 2018 Mar 08;12:9. doi: 10.3389/fnint.2018.00009. eCollection 2018. PMID: 29568264; PMCID: PMC5852382.
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Transobturator tape removal using a combined vaginal-transcutaneous approach for intractable groin pain.

Female pelvic medicine & reconstructive surgery

Gruber DD, Hernandez SL, Wright J, Fischer JR.
PMID: 22453673
Female Pelvic Med Reconstr Surg. 2011 Jan;17(1):55-7. doi: 10.1097/SPV.0b013e318204490c.

BACKGROUND: : Transient groin pain is a therapeutically challenging complication associated with transobturator sling procedures.CASE: : We present the case of a 37-year-old woman who presented with debilitating left groin pain and dyspareunia following placement of transobturator sling. Pelvic...

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Gruber DD, Hernandez SL, Wright J, et al. Transobturator tape removal using a combined vaginal-transcutaneous approach for intractable groin pain. Female Pelvic Med Reconstr Surg. 2011;17(1):55-7doi: 10.1097/SPV.0b013e318204490c.
Gruber, D. D., Hernandez, S. L., Wright, J., & Fischer, J. R. (2011). Transobturator tape removal using a combined vaginal-transcutaneous approach for intractable groin pain. Female pelvic medicine & reconstructive surgery, 17(1), 55-7. https://doi.org/10.1097/SPV.0b013e318204490c
Gruber, Daniel D, et al. "Transobturator tape removal using a combined vaginal-transcutaneous approach for intractable groin pain." Female pelvic medicine & reconstructive surgery vol. 17,1 (2011): 55-7. doi: https://doi.org/10.1097/SPV.0b013e318204490c
Gruber DD, Hernandez SL, Wright J, Fischer JR. Transobturator tape removal using a combined vaginal-transcutaneous approach for intractable groin pain. Female Pelvic Med Reconstr Surg. 2011 Jan;17(1):55-7. doi: 10.1097/SPV.0b013e318204490c. PMID: 22453673.
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Is changing footstrike pattern beneficial to runners?.

Journal of sport and health science

Hamill J, Gruber AH.
PMID: 30356626
J Sport Health Sci. 2017 Jun;6(2):146-153. doi: 10.1016/j.jshs.2017.02.004. Epub 2017 Feb 28.

Some researchers, running instructors, and coaches have suggested that the "optimal" footstrike pattern to improve performance and reduce running injuries is to land using a mid- or forefoot strike. Thus, it has been recommended that runners who use a...

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Hamill J, Gruber AH. Is changing footstrike pattern beneficial to runners?. J Sport Health Sci. 2017;6(2):146-153doi: 10.1016/j.jshs.2017.02.004.
Hamill, J., & Gruber, A. H. (2017). Is changing footstrike pattern beneficial to runners?. Journal of sport and health science, 6(2), 146-153. https://doi.org/10.1016/j.jshs.2017.02.004
Hamill, Joseph, and Gruber, Allison H. "Is changing footstrike pattern beneficial to runners?." Journal of sport and health science vol. 6,2 (2017): 146-153. doi: https://doi.org/10.1016/j.jshs.2017.02.004
Hamill J, Gruber AH. Is changing footstrike pattern beneficial to runners?. J Sport Health Sci. 2017 Jun;6(2):146-153. doi: 10.1016/j.jshs.2017.02.004. Epub 2017 Feb 28. PMID: 30356626; PMCID: PMC6189005.
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Quantifying exposure to running for meaningful insights into running-related injuries.

BMJ open sport & exercise medicine

Davis Iv JJ, Gruber AH.
PMID: 31673408
BMJ Open Sport Exerc Med. 2019 Oct 13;5(1):e000613. doi: 10.1136/bmjsem-2019-000613. eCollection 2019.

The very term 'running-related overuse injury' implies the importance of 'use', or exposure, to running. Risk factors for running-related injury can be better understood when exposure to running is quantified using either external or internal training loads. The advent...

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Davis Iv JJ, Gruber AH. Quantifying exposure to running for meaningful insights into running-related injuries. BMJ Open Sport Exerc Med. 2019;5(1):e000613doi: 10.1136/bmjsem-2019-000613.
Davis Iv, J. J., & Gruber, A. H. (2019). Quantifying exposure to running for meaningful insights into running-related injuries. BMJ open sport & exercise medicine, 5(1), e000613. https://doi.org/10.1136/bmjsem-2019-000613
Davis Iv, John J, and Gruber, Allison H. "Quantifying exposure to running for meaningful insights into running-related injuries." BMJ open sport & exercise medicine vol. 5,1 (2019): e000613. doi: https://doi.org/10.1136/bmjsem-2019-000613
Davis Iv JJ, Gruber AH. Quantifying exposure to running for meaningful insights into running-related injuries. BMJ Open Sport Exerc Med. 2019 Oct 13;5(1):e000613. doi: 10.1136/bmjsem-2019-000613. eCollection 2019. PMID: 31673408; PMCID: PMC6797407.
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No evidence of Sarcocystis calchasi involvement in mammalian meningoencephalitis of unknown origin.

Veterinary parasitology, regional studies and reports

Żuraw A, Plog S, Lierz M, Gruber AD.
PMID: 31014499
Vet Parasitol Reg Stud Reports. 2016 Jun;3:49-52. doi: 10.1016/j.vprsr.2016.05.006. Epub 2016 May 17.

Sarcocystis calchasi has recently been identified as the cause of pigeon protozoal encephalitis, PPE, a lethal brain disease in pigeons and parrots. While only avian species have been identified so far to be susceptible to this pathogen as definitive...

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Żuraw A, Plog S, Lierz M, et al. No evidence of Sarcocystis calchasi involvement in mammalian meningoencephalitis of unknown origin. Vet Parasitol Reg Stud Reports. 2016;3:49-52doi: 10.1016/j.vprsr.2016.05.006.
Żuraw, A., Plog, S., Lierz, M., & Gruber, A. D. (2016). No evidence of Sarcocystis calchasi involvement in mammalian meningoencephalitis of unknown origin. Veterinary parasitology, regional studies and reports, 349-52. https://doi.org/10.1016/j.vprsr.2016.05.006
Żuraw, Aleksandra, et al. "No evidence of Sarcocystis calchasi involvement in mammalian meningoencephalitis of unknown origin." Veterinary parasitology, regional studies and reports vol. 3 (2016): 49-52. doi: https://doi.org/10.1016/j.vprsr.2016.05.006
Żuraw A, Plog S, Lierz M, Gruber AD. No evidence of Sarcocystis calchasi involvement in mammalian meningoencephalitis of unknown origin. Vet Parasitol Reg Stud Reports. 2016 Jun;3:49-52. doi: 10.1016/j.vprsr.2016.05.006. Epub 2016 May 17. PMID: 31014499.
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Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Liutkevičiūtė Z, Gil-Mansilla E, Eder T, Casillas-Pérez B, Di Giglio MG, Muratspahić E, Grebien F, Rattei T, Muttenthaler M, Cremer S, Gruber CW.
PMID: 29939785
FASEB J. 2018 Jun 25;fj201800443. doi: 10.1096/fj.201800443. Epub 2018 Jun 25.

Ants are emerging model systems to study cellular signaling because distinct castes possess different physiologic phenotypes within the same colony. Here we studied the functionality of inotocin signaling, an insect ortholog of mammalian oxytocin (OT), which was recently discovered...

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Liutkevičiūtė Z, Gil-Mansilla E, Eder T, et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB J. 2018;fj201800443doi: 10.1096/fj.201800443.
Liutkevičiūtė, Z., Gil-Mansilla, E., Eder, T., Casillas-Pérez, B., Di Giglio, M. G., Muratspahić, E., Grebien, F., Rattei, T., Muttenthaler, M., Cremer, S., & Gruber, C. W. (2018). Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, fj201800443. https://doi.org/10.1096/fj.201800443
Liutkevičiūtė, Zita, et al. "Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity." FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. (2018): fj201800443. doi: https://doi.org/10.1096/fj.201800443
Liutkevičiūtė Z, Gil-Mansilla E, Eder T, Casillas-Pérez B, Di Giglio MG, Muratspahić E, Grebien F, Rattei T, Muttenthaler M, Cremer S, Gruber CW. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. FASEB J. 2018 Jun 25;fj201800443. doi: 10.1096/fj.201800443. Epub 2018 Jun 25. PMID: 29939785; PMCID: PMC6174076.
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Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders.

Neuroscience and biobehavioral reviews

Matisz CE, Gruber AJ.
PMID: 34929227
Neurosci Biobehav Rev. 2021 Dec 17;133:104497. doi: 10.1016/j.neubiorev.2021.12.020. Epub 2021 Dec 17.

Most gastrointestinal diseases and disorders (GIDD) are associated with depression, anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly chronic pain and inflammation, affect specific neural targets. The critical review of clinical and animal research presented...

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Matisz CE, Gruber AJ. Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders. Neurosci Biobehav Rev. 2021;133:104497doi: 10.1016/j.neubiorev.2021.12.020.
Matisz, C. E., & Gruber, A. J. (2021). Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders. Neuroscience and biobehavioral reviews, 133104497. https://doi.org/10.1016/j.neubiorev.2021.12.020
Matisz, C E, and Gruber, A J. "Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders." Neuroscience and biobehavioral reviews vol. 133 (2021): 104497. doi: https://doi.org/10.1016/j.neubiorev.2021.12.020
Matisz CE, Gruber AJ. Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders. Neurosci Biobehav Rev. 2021 Dec 17;133:104497. doi: 10.1016/j.neubiorev.2021.12.020. Epub 2021 Dec 17. PMID: 34929227.
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Bilateral differences in coordination variability among injured and uninjured runners: A prospective study.

Journal of biomechanics

Desai GA, Gruber AH.
PMID: 34998179
J Biomech. 2021 Dec 28;132:110938. doi: 10.1016/j.jbiomech.2021.110938. Epub 2021 Dec 28.

This prospective cohort study aimed to identify bilateral differences in coordination variability (CAV) to determine if limb-specific CAV or CAV asymmetry is associated with running-related overuse injury (RRI) development in recreational runners. Lower limb kinematics were collected at enrollment....

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Desai GA, Gruber AH. Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. J Biomech. 2021;132:110938doi: 10.1016/j.jbiomech.2021.110938.
Desai, G. A., & Gruber, A. H. (2021). Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. Journal of biomechanics, 132110938. https://doi.org/10.1016/j.jbiomech.2021.110938
Desai, Gauri A, and Gruber, Allison H. "Bilateral differences in coordination variability among injured and uninjured runners: A prospective study." Journal of biomechanics vol. 132 (2021): 110938. doi: https://doi.org/10.1016/j.jbiomech.2021.110938
Desai GA, Gruber AH. Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. J Biomech. 2021 Dec 28;132:110938. doi: 10.1016/j.jbiomech.2021.110938. Epub 2021 Dec 28. PMID: 34998179.
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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.

Nature communications

Ansari-Pour N, Zheng Y, Yoshimatsu TF, Sanni A, Ajani M, Reynier JB, Tapinos A, Pitt JJ, Dentro S, Woodard A, Rajagopal PS, Fitzgerald D, Gruber AJ, Odetunde A, Popoola A, Falusi AG, Babalola CP, Ogundiran T, Ibrahim N, Barretina J, Van Loo P, Chen M, White KP, Ojengbede O, Obafunwa J, Huo D, Wedge DC, Olopade OI.
PMID: 34836952
Nat Commun. 2021 Nov 26;12(1):6946. doi: 10.1038/s41467-021-27079-w.

Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European ancestry. Although inter-ethnic germline variation is known, differential somatic evolution has not been investigated in detail. Analysis of deep...

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Ansari-Pour N, Zheng Y, Yoshimatsu TF, et al. Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nat Commun. 2021;12(1):6946doi: 10.1038/s41467-021-27079-w.
Ansari-Pour, N., Zheng, Y., Yoshimatsu, T. F., Sanni, A., Ajani, M., Reynier, J. B., Tapinos, A., Pitt, J. J., Dentro, S., Woodard, A., Rajagopal, P. S., Fitzgerald, D., Gruber, A. J., Odetunde, A., Popoola, A., Falusi, A. G., Babalola, C. P., Ogundiran, T., Ibrahim, N., Barretina, J., Van Loo, P., Chen, M., White, K. P., Ojengbede, O., Obafunwa, J., Huo, D., Wedge, D. C., & Olopade, O. I. (2021). Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nature communications, 12(1), 6946. https://doi.org/10.1038/s41467-021-27079-w
Ansari-Pour, Naser, et al. "Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes." Nature communications vol. 12,1 (2021): 6946. doi: https://doi.org/10.1038/s41467-021-27079-w
Ansari-Pour N, Zheng Y, Yoshimatsu TF, Sanni A, Ajani M, Reynier JB, Tapinos A, Pitt JJ, Dentro S, Woodard A, Rajagopal PS, Fitzgerald D, Gruber AJ, Odetunde A, Popoola A, Falusi AG, Babalola CP, Ogundiran T, Ibrahim N, Barretina J, Van Loo P, Chen M, White KP, Ojengbede O, Obafunwa J, Huo D, Wedge DC, Olopade OI. Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nat Commun. 2021 Nov 26;12(1):6946. doi: 10.1038/s41467-021-27079-w. PMID: 34836952; PMCID: PMC8626467.
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Bilateral differences in coordination variability among injured and uninjured runners: A prospective study.

Journal of biomechanics

Desai GA, Gruber AH.
PMID: 34998179
J Biomech. 2021 Dec 28;132:110938. doi: 10.1016/j.jbiomech.2021.110938. Epub 2021 Dec 28.

This prospective cohort study aimed to identify bilateral differences in coordination variability (CAV) to determine if limb-specific CAV or CAV asymmetry is associated with running-related overuse injury (RRI) development in recreational runners. Lower limb kinematics were collected at enrollment....

Cite
Desai GA, Gruber AH. Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. J Biomech. 2021;132:110938doi: 10.1016/j.jbiomech.2021.110938.
Desai, G. A., & Gruber, A. H. (2021). Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. Journal of biomechanics, 132110938. https://doi.org/10.1016/j.jbiomech.2021.110938
Desai, Gauri A, and Gruber, Allison H. "Bilateral differences in coordination variability among injured and uninjured runners: A prospective study." Journal of biomechanics vol. 132 (2021): 110938. doi: https://doi.org/10.1016/j.jbiomech.2021.110938
Desai GA, Gruber AH. Bilateral differences in coordination variability among injured and uninjured runners: A prospective study. J Biomech. 2021 Dec 28;132:110938. doi: 10.1016/j.jbiomech.2021.110938. Epub 2021 Dec 28. PMID: 34998179.
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Showing 13 to 24 of 182 entries