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Showing 181 to 182 of 182 entries
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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.

Nature communications

Ansari-Pour N, Zheng Y, Yoshimatsu TF, Sanni A, Ajani M, Reynier JB, Tapinos A, Pitt JJ, Dentro S, Woodard A, Rajagopal PS, Fitzgerald D, Gruber AJ, Odetunde A, Popoola A, Falusi AG, Babalola CP, Ogundiran T, Ibrahim N, Barretina J, Van Loo P, Chen M, White KP, Ojengbede O, Obafunwa J, Huo D, Wedge DC, Olopade OI.
PMID: 34836952
Nat Commun. 2021 Nov 26;12(1):6946. doi: 10.1038/s41467-021-27079-w.

Black women across the African diaspora experience more aggressive breast cancer with higher mortality rates than white women of European ancestry. Although inter-ethnic germline variation is known, differential somatic evolution has not been investigated in detail. Analysis of deep...

Neuroinflammatory remodeling of the anterior cingulate cortex as a key driver of mood disorders in gastrointestinal disease and disorders.

Neuroscience and biobehavioral reviews

Matisz CE, Gruber AJ.
PMID: 34929227
Neurosci Biobehav Rev. 2021 Dec 17;133:104497. doi: 10.1016/j.neubiorev.2021.12.020. Epub 2021 Dec 17.

Most gastrointestinal diseases and disorders (GIDD) are associated with depression, anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly chronic pain and inflammation, affect specific neural targets. The critical review of clinical and animal research presented...

Showing 181 to 182 of 182 entries