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Showing 2401 to 2412 of 2417 entries
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cGMP signalling in dorsal root ganglia and the spinal cord: Various functions in development and adulthood.

British journal of pharmacology

Schmidt H, Böttcher A, Gross T, Schmidtko A.
PMID: 33939841
Br J Pharmacol. 2021 May 03; doi: 10.1111/bph.15514. Epub 2021 May 03.

Cyclic GMP (cGMP) is a second messenger that regulates numerous physiological and pathophysiological processes. In recent years, more and more studies have uncovered multiple roles of cGMP signalling pathways in the somatosensory system. Accumulating evidence suggests that cGMP regulates...

Using the COVID-19 pandemic to reimagine global health teaching in high-income countries.

BMJ global health

Atkins S, Banerjee AT, Bachynski K, Daftary A, Desai G, Gross A, Hedt-Gauthier B, Mendenhall E, Meier BM, Nixon SA, Nolan A, Palermo TM, Phelan A, Pyzik O, Roach P, Sangaramoorthy T, Standley CJ, Yamey G, Abimbola S, Pai M.
PMID: 33811100
BMJ Glob Health. 2021 Apr;6(4). doi: 10.1136/bmjgh-2021-005649.

No abstract available.

PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer.

PloS one

Darga EP, Dolce EM, Fang F, Kidwell KM, Gersch CL, Kregel S, Thomas DG, Gill A, Brown ME, Gross S, Connelly M, Holinstat M, Cobain EF, Rae JM, Hayes DF, Paoletti C.
PMID: 34780566
PLoS One. 2021 Nov 15;16(11):e0260124. doi: 10.1371/journal.pone.0260124. eCollection 2021.

BACKGROUND: Immune checkpoint inhibition is effective in several cancers. Expression of programmed death-ligand 1 (PD-L1) on circulating tumor or immune effector cells could provide insights into selection of patients for immune checkpoint inhibition.METHODS: Whole blood was collected at serial...

Left alone outside: A prospective observational cohort study on mental health outcomes among relatives of COVID-19 hospitalized patients.

Psychiatry research

Hertz-Palmor N, Gothelf D, Matalon N, Dorman-Ilan S, Basel D, Bursztyn S, Shani S, Mosheva M, Gross R, Pessach IM, Hasson-Ohayon I.
PMID: 34906830
Psychiatry Res. 2021 Dec 06;307:114328. doi: 10.1016/j.psychres.2021.114328. Epub 2021 Dec 06.

Hospitalization due to COVID-19 bears many psychological challenges. While focusing on infected patients, their relatives are being largely neglected. Here, we investigated the mental health implications of hospitalization among relatives, over a one-month course. A single center study was...

Neuroendocrine Neoplasm of the Breast Presenting as a Liver Metastasis: A Rare Diagnostic Challenge.

Cureus

Masab M, Gross A, Flanagan M, Goldberg R, Malla M.
PMID: 34513437
Cureus. 2021 Aug 03;13(8):e16860. doi: 10.7759/cureus.16860. eCollection 2021 Aug.

We present a case of a 58-year-old female who presented initially to an outside institution with abdominal pain and was diagnosed on liver biopsy with a well-differentiated neuroendocrine tumor of an unknown primary source. She was referred to our...

Long-Term Safety and Efficacy of Deutetrabenazine in Younger and Older Patients With Tardive Dyskinesia.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Sajatovic M, Finkbeiner S, Wilhelm A, Barkay H, Chaijale N, Gross N, Gordon MF.
PMID: 34511333
Am J Geriatr Psychiatry. 2021 Aug 16; doi: 10.1016/j.jagp.2021.08.003. Epub 2021 Aug 16.

OBJECTIVES: To assess long-term safety and efficacy of deutetrabenazine in younger (

Draft Genome Sequence of the Halophilic Strain Citrobacter braakii AN-PRR1, Isolated from Rhizospheric Soil of Rice (Oryza sativa L.) from Pakistan.

Microbiology resource announcements

Nawaz A, Mubeen F, Qamar ZU, Marghoob MU, Aziz S, Gross H.
PMID: 34553999
Microbiol Resour Announc. 2021 Sep 23;10(38):e0078721. doi: 10.1128/MRA.00787-21. Epub 2021 Sep 23.

Citrobacter braakii AN-PRR1 is a potential salt-tolerant, plant growth-promoting rice rhizobacterium isolated from Pakistani soil. The 4.9-Mb draft genome sequence contributes to its taxonomic classification and will reveal the genes putatively responsible for its osmoprotectant and plant growth-promoting activity.

Predicting solvation free energies in non-polar solvents using classical density functional theory based on the PC-SAFT equation of state.

The Journal of chemical physics

Eller J, Matzerath T, van Westen T, Gross J.
PMID: 34241354
J Chem Phys. 2021 Jun 28;154(24):244106. doi: 10.1063/5.0051201.

We propose a predictive Density Functional Theory (DFT) for the calculation of solvation free energies. Our approach is based on a Helmholtz free-energy functional that is consistent with the Perturbed-Chain Statistical Associating Fluid Theory (PC-SAFT) equation of state. This...

An on-surface Diels-Alder reaction.

Angewandte Chemie (International ed. in English)

Castro-Esteban J, Albrecht F, Fatayer S, Pérez D, Gross L, Peña D.
PMID: 34664770
Angew Chem Int Ed Engl. 2021 Dec 06;60(50):26346-26350. doi: 10.1002/anie.202110311. Epub 2021 Nov 10.

The Diels-Alder reaction is one of the most popular reactions in organic chemistry. However, its use in the field of on-surface synthesis is hampered by the spatial restrictions of this cycloaddition reaction. Herein we selected a cyclic strained triyne...

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.

PLoS pathogens

Tran TT, Mathmann CD, Gatica-Andrades M, Rollo RF, Oelker M, Ljungberg JK, Nguyen TTK, Zamoshnikova A, Kummari LK, Wyer OJK, Irvine KM, Melo-Bolívar J, Gross A, Brown D, Mak JYW, Fairlie DP, Hansford KA, Cooper MA, Giri R, Schreiber V, Joseph SR, Simpson F, Barnett TC, Johansson J, Dankers W, Harris J, Wells TJ, Kapetanovic R, Sweet MJ, Latomanski EA, Newton HJ, Guérillot RJR, Hachani A, Stinear TP, Ong SY, Chandran Y, Hartland EL, Kobe B, Stow JL, Sauer-Eriksson AE, Begun J, Kling JC, Blumenthal A.
PMID: 35007292
PLoS Pathog. 2022 Jan 10;18(1):e1010166. doi: 10.1371/journal.ppat.1010166. eCollection 2022 Jan.

A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in the host cell cytoplasm and cell-to-cell spread. The bacterial transcriptional activator PrfA controls expression of key virulence...

Why do people follow social norms?.

Current opinion in psychology

Gross J, Vostroknutov A.
PMID: 34520935
Curr Opin Psychol. 2021 Aug 19;44:1-6. doi: 10.1016/j.copsyc.2021.08.016. Epub 2021 Aug 19.

Norms prescribe how to make decisions in social situations and play a crucial role in sustaining cooperative relationships and coordinating collective action. However, following norms often requires restricting behavior, demanding to curtail selfishness, or suppressing personal goals. This raises...

Local tissue interactions govern pLL patterning in medaka.

Developmental biology

Seleit A, Gross K, Onistschenko J, Hoang OP, Theelke J, Centanin L.
PMID: 34517003
Dev Biol. 2022 Jan;481:1-13. doi: 10.1016/j.ydbio.2021.09.002. Epub 2021 Sep 11.

Vertebrate organs are arranged in a stereotypic, species-specific position along the animal body plan. Substantial morphological variation exists between related species, especially so in the vastly diversified teleost clade. It is still unclear how tissues, organs and systems can...

Showing 2401 to 2412 of 2417 entries