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Showing 9985 to 9996 of 13189 entries
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Calcitonin increases hepatic hepcidin expression through the BMP6 of kidney in mice.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Lei Y, Zhao C, Chang H, Zhang D, Li Y, Anderson GJ, Shen Y, Duan X, Chang YZ.
PMID: 34098241
J Trace Elem Med Biol. 2021 Dec;68:126796. doi: 10.1016/j.jtemb.2021.126796. Epub 2021 Jun 01.

BACKGROUND: Osteoporosis is frequently accompanied by iron disorders. Calcitonin (CT) was approved as a clinical drug to treat osteoporosis. Hepcidin is a peptide hormone that is secreted by the liver and controls body iron homeostasis. Hepcidin deficiency leads to...

Intraoperative transit-time flow measurement and high-frequency ultrasound in coronary artery bypass grafting: impact in off versus on-pump, arterial versus venous grafting and cardiac territory grafted.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

Rosenfeld ES, Trachiotis GD, Napolitano MA, Sparks AD, Wendt D, Kieser TM, Puskas JD, DiGiammarco G, Taggart DP.
PMID: 34166508
Eur J Cardiothorac Surg. 2021 Dec 27;61(1):204-213. doi: 10.1093/ejcts/ezab239.

OBJECTIVES: Despite society guideline recommendations, intraoperative high-frequency ultrasound (HFUS) and transit-time flow measurement (TTFM) use in coronary artery bypass grafting (CABG) has not been widely adopted worldwide. This retrospective review of the REQUEST (REgistry for QUality assESsmenT with Ultrasound...

Low frequency novel interictal EEG biomarker for localizing seizures and predicting outcomes.

Brain communications

Lundstrom BN, Brinkmann BH, Worrell GA.
PMID: 34704030
Brain Commun. 2021 Oct 06;3(4):fcab231. doi: 10.1093/braincomms/fcab231. eCollection 2021.

Localizing hyperexcitable brain tissue to treat focal seizures remains challenging. We want to identify the seizure onset zone from interictal EEG biomarkers. We hypothesize that a combination of interictal EEG biomarkers, including a novel low frequency marker, can predict...

The Chesapeake Bay Program Modeling System: Overview and Recommendations for Future Development.

Ecological modelling

Hood RR, Shenk GW, Dixon RL, Smith SMC, Ball WP, Bash JO, Batiuk R, Boomer K, Brady DC, Cerco C, Claggett P, de Mutsert K, Easton ZM, Elmore AJ, Friedrichs MAM, Harris LA, Ihde TF, Lacher I, Li L, Linker LC, Miller A, Moriarty J, Noe GB, Onyullo G, Rose K, Skalak K, Tian R, Veith TL, Wainger L, Weller D, Zhang YJ.
PMID: 34675451
Ecol Modell. 2021 Sep 15;465:1-109635. doi: 10.1016/j.ecolmodel.2021.109635.

The Chesapeake Bay is the largest, most productive, and most biologically diverse estuary in the continental United States providing crucial habitat and natural resources for culturally and economically important species. Pressures from human population growth and associated development and...

Mechanisms of IR amplification in radical cation polarons.

Chemical science

Kendrick WJ, Jirásek M, Peeks MD, Greetham GM, Sazanovich IV, Donaldson PM, Towrie M, Parker AW, Anderson HL.
PMID: 34123299
Chem Sci. 2020 Jan 22;11(8):2112-2120. doi: 10.1039/c9sc05717j.

Break down of the Born-Oppenheimer approximation is caused by mixing of electronic and vibrational transitions in the radical cations of some conjugated polymers, resulting in unusually intense vibrational bands known as infrared active vibrations (IRAVs). Here, we investigate the...

Monomeric IgA Antagonizes IgG-Mediated Enhancement of DENV Infection.

Frontiers in immunology

Wegman AD, Fang H, Rothman AL, Thomas SJ, Endy TP, McCracken MK, Currier JR, Friberg H, Gromowski GD, Waickman AT.
PMID: 34899736
Front Immunol. 2021 Nov 24;12:777672. doi: 10.3389/fimmu.2021.777672. eCollection 2021.

Dengue virus (DENV) is a prevalent human pathogen, infecting approximately 400 million individuals per year and causing symptomatic disease in approximately 100 million. A distinct feature of dengue is the increased risk for severe disease in some individuals with...

Identifying 3-D spatiotemporal skin deformation cues evoked in interacting with compliant elastic surfaces.

IEEE Haptics Symposium : [proceedings]. IEEE Haptics Symposium

Li B, Hauser S, Gerling GJ.
PMID: 34458383
IEEE Haptics Symp. 2020 Mar;2020:35-40. doi: 10.1109/haptics45997.2020.ras.hap20.22.5a9b38d8. Epub 2020 May 07.

We regularly touch soft, compliant fruits and tissues. To help us discriminate them, we rely upon cues embedded in spatial and temporal deformation of finger pad skin. However, we do not yet understand, in touching objects of various compliance,...

Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2 : A Prospective Cohort Study.

Annals of internal medicine

Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, Demissie EG, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Pawar N, Perantie DC, Schriefer RE, Sides SE, Thapa M, Gergely M, Abushamma S, Akuse S, Klebert M, Mitchell L, Nix D, Graf J, Taylor KE, Chahin S, Ciorba MA, Katz P, Matloubian M, O'Halloran JA, Presti RM, Wu GF, Whelan SPJ, Buchser WJ, Gensler LS, Nakamura MC, Ellebedy AH, Kim AHJ.
PMID: 34461029
Ann Intern Med. 2021 Nov;174(11):1572-1585. doi: 10.7326/M21-1757. Epub 2021 Aug 31.

BACKGROUND: Patients with chronic inflammatory disease (CID) treated with immunosuppressive medications have increased risk for severe COVID-19. Although mRNA-based SARS-CoV-2 vaccination provides protection in immunocompetent persons, immunogenicity in immunosuppressed patients with CID is unclear.OBJECTIVE: To determine the immunogenicity of...

Does Gene Editing in the Wild Require Broad Public Deliberation?.

The Hastings Center report

Kaebnick GE.
PMID: 34905251
Hastings Cent Rep. 2021 Nov;51:S34-S41. doi: 10.1002/hast.1318.

How strong is the argument for requiring public deliberation by very large publics-at national or even global levels-before moving forward with efforts to use gene editing on wild populations of plants or animals? Should there be a general moratorium...

Tricuspid valve disease prevalence and the impact of tricuspid valve surgery on cardiovascular events and hospital resource use in medicare beneficiaries.

American heart journal

Vemulapalli S, Kerr MSD, Roberts GJ, Prillinger JB, Meduri CU, McCarthy P.
PMID: 34932999
Am Heart J. 2021 Dec 18;245:100-109. doi: 10.1016/j.ahj.2021.12.001. Epub 2021 Dec 18.

BACKGROUND: Tricuspid valve disease (TVD) is presumed common, however, little is known about its prevalence or the impact of tricuspid valve surgery (TVS) on healthcare resource use.METHODS: To describe the prevalence of TVD and assess the impact of TVS...

Provider REport of Sustainment Scale (PRESS): development and validation of a brief measure of inner context sustainment.

Implementation science : IS

Moullin JC, Sklar M, Ehrhart MG, Green A, Aarons GA.
PMID: 34461948
Implement Sci. 2021 Aug 30;16(1):86. doi: 10.1186/s13012-021-01152-w.

BACKGROUND: Implementation scientists and practitioners often rely on frontline providers for reporting on implementation outcomes. Furthermore, measures of sustainment are few, and available sustainment measures are mainly setting or evidenced-based practice (EBP) specific, require organizational and system-level knowledge to...

The Effect of Age on Performance of the Kidney Failure Risk Equation in Advanced CKD.

Kidney international reports

Hundemer GL, Tangri N, Sood MM, Clark EG, Canney M, Edwards C, White CA, Oliver MJ, Ramsay T, Akbari A.
PMID: 34901569
Kidney Int Rep. 2021 Oct 08;6(12):2993-3001. doi: 10.1016/j.ekir.2021.09.006. eCollection 2021 Dec.

INTRODUCTION: The Kidney Failure Risk Equation (KFRE) is a clinical tool widely used to predict progression from chronic kidney disease (CKD) to kidney failure. This study aimed to evaluate the effect of age on KFRE performance in advanced CKD.METHODS:...

Showing 9985 to 9996 of 13189 entries