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Showing 25 to 36 of 66 entries
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Characterization of an APC Promoter 1B deletion in a Patient Diagnosed with Familial Adenomatous Polyposis via Whole Genome Shotgun Sequencing.

F1000Research

Kalbfleisch T, Brock P, Snow A, Neklason D, Gowans G, Klein J.
PMID: 26213617
F1000Res. 2015 Jun 26;4:170. doi: 10.12688/f1000research.6636.1. eCollection 2015.

Recently, deletions have been identified and published as causal for Familial Adenomatous Polyposis in the 1B promoter region of the APC gene.  Those deletions were measured using multiplex ligation-dependent probe amplification.  Here, we present and characterize an ~11kb deletion...

Multivariate pattern analysis strategies in detection of remitted major depressive disorder using resting state functional connectivity.

NeuroImage. Clinical

Bhaumik R, Jenkins LM, Gowins JR, Jacobs RH, Barba A, Bhaumik DK, Langenecker SA.
PMID: 28861340
Neuroimage Clin. 2016 Mar 02;16:390-398. doi: 10.1016/j.nicl.2016.02.018. eCollection 2017.

Understanding abnormal resting-state functional connectivity of distributed brain networks may aid in probing and targeting mechanisms involved in major depressive disorder (MDD). To date, few studies have used resting state functional magnetic resonance imaging (rs-fMRI) to attempt to discriminate...

Case of Pernicious Anæmia, with Febrile Symptoms, Proving Fatal Three Months after Delivery.

Glasgow medical journal

Gowans J.
PMID: 30433075
Glasgow Med J. 1876 Jul;8(3):349-352.

No abstract available.

Case of Lymphatic Leukæmia, with Tumour in the Mediastinum.

Glasgow medical journal

Gowans J.
PMID: 30433041
Glasgow Med J. 1876 Oct;8(4):433-438.

No abstract available.

PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes.

iScience

Owens JL, Beketova E, Liu S, Tinsley SL, Asberry AM, Deng X, Huang J, Li C, Wan J, Hu CD.
PMID: 31884170
iScience. 2020 Jan 24;23(1):100750. doi: 10.1016/j.isci.2019.100750. Epub 2019 Nov 29.

DNA double-strand break (DSB) repair is critical for cell survival and genome integrity. Upon recognition of DSBs, repair proteins are transiently upregulated to facilitate repair through homologous recombination (HR) or non-homologous end joining (NHEJ). We present evidence that PRMT5...

Thyroid Hormone Distributor Proteins During Development in Vertebrates.

Frontiers in endocrinology

Rabah SA, Gowan IL, Pagnin M, Osman N, Richardson SJ.
PMID: 31440205
Front Endocrinol (Lausanne). 2019 Aug 08;10:506. doi: 10.3389/fendo.2019.00506. eCollection 2019.

Thyroid hormones (THs) are ancient hormones that not only influence the growth, development and metabolism of vertebrates but also affect the metabolism of (at least some) bacteria. Synthesized in the thyroid gland (or follicular cells in fish not having...

Reliability, Convergent Validity and Time Invariance of Default Mode Network Deviations in Early Adult Major Depressive Disorder.

Frontiers in psychiatry

Bessette KL, Jenkins LM, Skerrett KA, Gowins JR, DelDonno SR, Zubieta JK, McInnis MG, Jacobs RH, Ajilore O, Langenecker SA.
PMID: 29937738
Front Psychiatry. 2018 Jun 08;9:244. doi: 10.3389/fpsyt.2018.00244. eCollection 2018.

There is substantial variability across studies of default mode network (DMN) connectivity in major depressive disorder, and reliability and time-invariance are not reported. This study evaluates whether DMN dysconnectivity in remitted depression (rMDD) is reliable over time and symptom-independent,...

Variant analyses of candidate genes in orofacial clefts in multi-ethnic populations.

Oral diseases

Li M, Olotu J, Buxo-Martinez CJ, Mossey PA, Anand D, Busch T, Alade A, Gowans LJJ, Eshete M, Adeyemo WL, Naicker T, Awotoye WO, Gupta S, Adeleke C, Bravo V, Huang S, Adamson OO, Toraño AM, Bello CA, Soto M, Soto M, Ledesma R, Marquez M, Cordero JF, Lopez-Del Valle LM, Salcedo MI, Debs N, Petrin A, Malloy H, Elhadi K, James O, Ogunlewe MO, Abate F, Hailu A, Mohammed I, Gravem P, Deribew M, Gesses M, Hassan M, Pape J, Obiri-Yeboah S, Arthur FKN, Oti AA, Donkor P, Marazita ML, Lachke SA, Adeyemo AA, Murray JC, Butali A.
PMID: 34061439
Oral Dis. 2021 Jun 01; doi: 10.1111/odi.13932. Epub 2021 Jun 01.

OBJECTIVES: Cleft lip with/without cleft palate and cleft palate only is congenital birth defects where the upper lip and/or palate fail to fuse properly during embryonic facial development. Affecting ~1.2/1000 live births worldwide, these orofacial clefts impose significant social...

Effect of litter size on blood haematocrit and liveweight in Booroola Merino and Merino ewes during pregnancy and the post-partum period.

Theriogenology

Owens JL, Bindon BM, Edey TN, Piper LR.
PMID: 16725990
Theriogenology. 1984 Nov;22(5):579-86. doi: 10.1016/0093-691x(84)90057-8.

Blood haematocrit and liveweight were determined throughout pregnancy and the post-partum period in 217 Booroola Merino and Merino ewes in order to relate these parameters to litter size at birth. In pregnant ewes, haematocrit declined from three until five...

Emerging Targets for Developing T Cell-Mediated Vaccines for Human Immunodeficiency Virus (HIV)-1.

Frontiers in microbiology

Wijesundara DK, Ranasinghe C, Grubor-Bauk B, Gowans EJ.
PMID: 29118747
Front Microbiol. 2017 Oct 25;8:2091. doi: 10.3389/fmicb.2017.02091. eCollection 2017.

Human immunodeficiency virus (HIV)-1 has infected >75 million individuals globally, and, according to the UN, is responsible for ~2.1 million new infections and 1.1 million deaths each year. Currently, there are ~37 million individuals with HIV infection and the...

Complete Genome Sequences of Cluster A Mycobacteriophages BobSwaget, Fred313, KADY, Lokk, MyraDee, Stagni, and StepMih.

Genome announcements

Butela KA, Gurney SMR, Hendrickson HL, LeBlanc-Straceski JM, Zimmerman AM, Conant SB, Freed NE, Silander OK, Thomson JJ, Berkes CA, Bertolez C, Davies CG, Elinsky A, Hanlon AJ, Nersesyan J, Patel P, Sherwood J, Tieu Ngo T, Wisniewski KA, Yacoo K, Arendse PM, Bowlen NW, Cunmulaj J, Downs JL, Ferrenberg CA, Gassman AE, Gilligan CER, Gorkiewicz E, Harness C, Huffman A, Jones C, Julien A, Kupic AE, Latu SF, Manning TJ, Maxwell D, Meyer CE, Reardon M, Slaughter M, Swasey R, Tennent RI, Torres V, Waller T, Worcester RM, Yost BL, Cresawn SG, Garlena RA, Jacobs-Sera D, Pope WH, Russell DA, Hatfull GF, Kagey JD.
PMID: 29074662
Genome Announc. 2017 Oct 26;5(43). doi: 10.1128/genomeA.01182-17.

Seven mycobacteriophages from distinct geographical locations were isolated, using

Doubling down: increased risk-taking behavior following a loss by individuals with cocaine use disorder is associated with striatal and anterior cingulate dysfunction.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Gowin JL, May AC, Wittmann M, Tapert SF, Paulus MP.
PMID: 28164168
Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jan;2(1):94-103. doi: 10.1016/j.bpsc.2016.02.002.

BACKGROUND: Cocaine use disorders (CUDs) have been associated with increased risk-taking behavior. Neuroimaging studies have suggested that altered activity in reward and decision-making circuitry may underlie cocaine user's heightened risk-taking. It remains unclear if this behavior is driven by...

Showing 25 to 36 of 66 entries