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Impact of COVID-19 on IR Fellowship.

Journal of vascular and interventional radiology : JVIR

Xiao N, Gordon AC, Thornburg B, Sato KT, Lewandowski RJ.
PMID: 32771280
J Vasc Interv Radiol. 2020 Sep;31(9):1492-1494. doi: 10.1016/j.jvir.2020.06.021. Epub 2020 Jul 02.

No abstract available.

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Xiao N, Gordon AC, Thornburg B, et al. Impact of COVID-19 on IR Fellowship. J Vasc Interv Radiol. 2020;31(9):1492-1494doi: 10.1016/j.jvir.2020.06.021.
Xiao, N., Gordon, A. C., Thornburg, B., Sato, K. T., & Lewandowski, R. J. (2020). Impact of COVID-19 on IR Fellowship. Journal of vascular and interventional radiology : JVIR, 31(9), 1492-1494. https://doi.org/10.1016/j.jvir.2020.06.021
Xiao, Nicholas, et al. "Impact of COVID-19 on IR Fellowship." Journal of vascular and interventional radiology : JVIR vol. 31,9 (2020): 1492-1494. doi: https://doi.org/10.1016/j.jvir.2020.06.021
Xiao N, Gordon AC, Thornburg B, Sato KT, Lewandowski RJ. Impact of COVID-19 on IR Fellowship. J Vasc Interv Radiol. 2020 Sep;31(9):1492-1494. doi: 10.1016/j.jvir.2020.06.021. Epub 2020 Jul 02. PMID: 32771280; PMCID: PMC7330558.
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Procedures for establishing defensible programmes for assessing practice performance.

Medical education

Lew SR, Page GG, Schuwirth LW, Baron-Maldonado M, Lescop JM, Paget NS, J Southgate L, Wade WB.
PMID: 12390461
Med Educ. 2002 Oct;36(10):936-41. doi: 10.1046/j.1365-2923.2002.01319.x.

The assessment of the performance of doctors in practice is becoming more widely accepted. While there are many potential purposes for such assessments, sometimes the consequences of the assessments will be 'high stakes'. In these circumstances, any of the...

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Lew SR, Page GG, Schuwirth LW, et al. Procedures for establishing defensible programmes for assessing practice performance. Med Educ. 2002;36(10):936-41doi: 10.1046/j.1365-2923.2002.01319.x.
Lew, S. R., Page, G. G., Schuwirth, L. W., Baron-Maldonado, M., Lescop, J. M., Paget, N. S., J Southgate, L., & Wade, W. B. (2002). Procedures for establishing defensible programmes for assessing practice performance. Medical education, 36(10), 936-41. https://doi.org/10.1046/j.1365-2923.2002.01319.x
Lew, Stephen R, et al. "Procedures for establishing defensible programmes for assessing practice performance." Medical education vol. 36,10 (2002): 936-41. doi: https://doi.org/10.1046/j.1365-2923.2002.01319.x
Lew SR, Page GG, Schuwirth LW, Baron-Maldonado M, Lescop JM, Paget NS, J Southgate L, Wade WB. Procedures for establishing defensible programmes for assessing practice performance. Med Educ. 2002 Oct;36(10):936-41. doi: 10.1046/j.1365-2923.2002.01319.x. PMID: 12390461.
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Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial.

Journal of the Intensive Care Society

Richards-Belle A, Mouncey PR, Grieve RD, Harrison DA, Sadique MZ, Henry D, Whitman C, Camsooksai J, Gordon AC, Young JD, Rowan KM, Lamontagne F.
PMID: 34093727
J Intensive Care Soc. 2020 Nov;21(4):281-282. doi: 10.1177/1751143720971433. Epub 2020 Dec 08.

Vasodilatory shock is common in critically ill patients and vasopressors are a mainstay of therapy. A meta-analysis suggested that use of a higher, as opposed to a lower, mean arterial pressure target to guide titration of vasopressor therapy, could...

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Richards-Belle A, Mouncey PR, Grieve RD, et al. Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial. J Intensive Care Soc. 2020;21(4):281-282doi: 10.1177/1751143720971433.
Richards-Belle, A., Mouncey, P. R., Grieve, R. D., Harrison, D. A., Sadique, M. Z., Henry, D., Whitman, C., Camsooksai, J., Gordon, A. C., Young, J. D., Rowan, K. M., & Lamontagne, F. (2020). Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial. Journal of the Intensive Care Society, 21(4), 281-282. https://doi.org/10.1177/1751143720971433
Richards-Belle, Alvin, et al. "Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial." Journal of the Intensive Care Society vol. 21,4 (2020): 281-282. doi: https://doi.org/10.1177/1751143720971433
Richards-Belle A, Mouncey PR, Grieve RD, Harrison DA, Sadique MZ, Henry D, Whitman C, Camsooksai J, Gordon AC, Young JD, Rowan KM, Lamontagne F. Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial. J Intensive Care Soc. 2020 Nov;21(4):281-282. doi: 10.1177/1751143720971433. Epub 2020 Dec 08. PMID: 34093727; PMCID: PMC8142090.
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BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators.

Theranostics

Castellanet O, Ahmad F, Vinik Y, Mills GB, Habermann B, Borg JP, Lev S, Lamballe F, Maina F.
PMID: 34646365
Theranostics. 2021 Sep 03;11(19):9180-9197. doi: 10.7150/thno.60503. eCollection 2021.

Cell cycle regulators are frequently altered in Triple-Negative Breast Cancer (TNBC). Emerging agents targeting these signals offer the possibility to design new combinatorial therapies. However, preclinical models that recapitulate TNBC primary resistance and heterogeneity are essential to evaluate the...

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Castellanet O, Ahmad F, Vinik Y, et al. BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators. Theranostics. 2021;11(19):9180-9197doi: 10.7150/thno.60503.
Castellanet, O., Ahmad, F., Vinik, Y., Mills, G. B., Habermann, B., Borg, J. P., Lev, S., Lamballe, F., & Maina, F. (2021). BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators. Theranostics, 11(19), 9180-9197. https://doi.org/10.7150/thno.60503
Castellanet, Olivier, et al. "BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators." Theranostics vol. 11,19 (2021): 9180-9197. doi: https://doi.org/10.7150/thno.60503
Castellanet O, Ahmad F, Vinik Y, Mills GB, Habermann B, Borg JP, Lev S, Lamballe F, Maina F. BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators. Theranostics. 2021 Sep 03;11(19):9180-9197. doi: 10.7150/thno.60503. eCollection 2021. PMID: 34646365; PMCID: PMC8490507.
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A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi.

EBioMedicine

Morton B, Burr S, Chikaonda T, Nsomba E, Manda-Taylor L, Henrion MYR, Banda NP, Rylance J, Ferreira DM, Jambo K, Gordon SB.
PMID: 34571365
EBioMedicine. 2021 Oct;72:103579. doi: 10.1016/j.ebiom.2021.103579. Epub 2021 Sep 24.

BACKGROUND: Persistent carriage of pneumococcal vaccine serotypes has occurred after introduction of PCV13 vaccination in Africa but the mechanisms are unclear. We tested the feasibility of using a human pneumococcal challenge model in Malawi to understand immune correlates of...

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Morton B, Burr S, Chikaonda T, et al. A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi. EBioMedicine. 2021;72:103579doi: 10.1016/j.ebiom.2021.103579.
Morton, B., Burr, S., Chikaonda, T., Nsomba, E., Manda-Taylor, L., Henrion, M. Y. R., Banda, N. P., Rylance, J., Ferreira, D. M., Jambo, K., Gordon, S. B. (2021). A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi. EBioMedicine, 72103579. https://doi.org/10.1016/j.ebiom.2021.103579
Morton, Ben, et al. "A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi." EBioMedicine vol. 72 (2021): 103579. doi: https://doi.org/10.1016/j.ebiom.2021.103579
Morton B, Burr S, Chikaonda T, Nsomba E, Manda-Taylor L, Henrion MYR, Banda NP, Rylance J, Ferreira DM, Jambo K, Gordon SB. A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi. EBioMedicine. 2021 Oct;72:103579. doi: 10.1016/j.ebiom.2021.103579. Epub 2021 Sep 24. PMID: 34571365; PMCID: PMC8479630.
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Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor.

ACS chemical biology

Gordon JB, Hoffman MC, Troiano JM, Li M, Hazelbauer GL, Schlau-Cohen GS.
PMID: 34647725
ACS Chem Biol. 2021 Nov 19;16(11):2472-2480. doi: 10.1021/acschembio.1c00576. Epub 2021 Oct 14.

Transmembrane receptors are central components of the chemosensory systems by which motile bacteria detect and respond to chemical gradients. An attractant bound to the receptor periplasmic domain generates conformational signals that regulate a histidine kinase interacting with its cytoplasmic...

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Gordon JB, Hoffman MC, Troiano JM, et al. Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor. ACS Chem Biol. 2021;16(11):2472-2480doi: 10.1021/acschembio.1c00576.
Gordon, J. B., Hoffman, M. C., Troiano, J. M., Li, M., Hazelbauer, G. L., & Schlau-Cohen, G. S. (2021). Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor. ACS chemical biology, 16(11), 2472-2480. https://doi.org/10.1021/acschembio.1c00576
Gordon, Jesse B, et al. "Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor." ACS chemical biology vol. 16,11 (2021): 2472-2480. doi: https://doi.org/10.1021/acschembio.1c00576
Gordon JB, Hoffman MC, Troiano JM, Li M, Hazelbauer GL, Schlau-Cohen GS. Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor. ACS Chem Biol. 2021 Nov 19;16(11):2472-2480. doi: 10.1021/acschembio.1c00576. Epub 2021 Oct 14. PMID: 34647725.
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Understanding the Potential Impact of Different Drug Properties On SARS-CoV-2 Transmission and Disease Burden: A Modelling Analysis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Whittaker C, Watson OJ, Alvarez-Moreno C, Angkasekwinai N, Boonyasiri A, Carlos Triana L, Chanda D, Charoenpong L, Chayakulkeeree M, Cooke GS, Croda J, Cucunubá ZM, Djaafara BA, Estofolete CF, Grillet ME, Faria NR, Figueiredo Costa S, Forero-Peña DA, Gibb DM, Gordon AC, Hamers RL, Hamlet A, Irawany V, Jitmuang A, Keurueangkul N, Kimani TN, Lampo M, Levin AS, Lopardo G, Mustafa R, Nayagam S, Ngamprasertchai T, Njeri NIH, Nogueira ML, Ortiz-Prado E, Perroud MW, Phillips AN, Promsin P, Qavi A, Rodger AJ, Sabino EC, Sangkaew S, Sari D, Sirijatuphat R, Sposito AC, Srisangthong P, Thompson HA, Udwadia Z, Valderrama-Beltrán S, Winskill P, Ghani AC, Walker PGT, Hallett TB.
PMID: 34549260
Clin Infect Dis. 2021 Sep 21; doi: 10.1093/cid/ciab837. Epub 2021 Sep 21.

BACKGROUND: The public health impact of the COVID-19 pandemic has motivated a rapid search for potential therapeutics, with some key successes. However, the potential impact of different treatments, and consequently research and procurement priorities, have not been clear.METHODS: Using...

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Whittaker C, Watson OJ, Alvarez-Moreno C, et al. Understanding the Potential Impact of Different Drug Properties On SARS-CoV-2 Transmission and Disease Burden: A Modelling Analysis. Clin Infect Dis. 2021;doi: 10.1093/cid/ciab837.
Whittaker, C., Watson, O. J., Alvarez-Moreno, C., Angkasekwinai, N., Boonyasiri, A., Carlos Triana, L., Chanda, D., Charoenpong, L., Chayakulkeeree, M., Cooke, G. S., Croda, J., Cucunubá, Z. M., Djaafara, B. A., Estofolete, C. F., Grillet, M. E., Faria, N. R., Figueiredo Costa, S., Forero-Peña, D. A., Gibb, D. M., Gordon, A. C., Hamers, R. L., Hamlet, A., Irawany, V., Jitmuang, A., Keurueangkul, N., Kimani, T. N., Lampo, M., Levin, A. S., Lopardo, G., Mustafa, R., Nayagam, S., Ngamprasertchai, T., Njeri, N. I. H., Nogueira, M. L., Ortiz-Prado, E., Perroud, M. W., Phillips, A. N., Promsin, P., Qavi, A., Rodger, A. J., Sabino, E. C., Sangkaew, S., Sari, D., Sirijatuphat, R., Sposito, A. C., Srisangthong, P., Thompson, H. A., Udwadia, Z., Valderrama-Beltrán, S., Winskill, P., Ghani, A. C., Walker, P. G. T., & Hallett, T. B. (2021). Understanding the Potential Impact of Different Drug Properties On SARS-CoV-2 Transmission and Disease Burden: A Modelling Analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, . https://doi.org/10.1093/cid/ciab837
Whittaker, Charles, et al. "Understanding the Potential Impact of Different Drug Properties On SARS-CoV-2 Transmission and Disease Burden: A Modelling Analysis." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America vol. (2021). doi: https://doi.org/10.1093/cid/ciab837
Whittaker C, Watson OJ, Alvarez-Moreno C, Angkasekwinai N, Boonyasiri A, Carlos Triana L, Chanda D, Charoenpong L, Chayakulkeeree M, Cooke GS, Croda J, Cucunubá ZM, Djaafara BA, Estofolete CF, Grillet ME, Faria NR, Figueiredo Costa S, Forero-Peña DA, Gibb DM, Gordon AC, Hamers RL, Hamlet A, Irawany V, Jitmuang A, Keurueangkul N, Kimani TN, Lampo M, Levin AS, Lopardo G, Mustafa R, Nayagam S, Ngamprasertchai T, Njeri NIH, Nogueira ML, Ortiz-Prado E, Perroud MW, Phillips AN, Promsin P, Qavi A, Rodger AJ, Sabino EC, Sangkaew S, Sari D, Sirijatuphat R, Sposito AC, Srisangthong P, Thompson HA, Udwadia Z, Valderrama-Beltrán S, Winskill P, Ghani AC, Walker PGT, Hallett TB. Understanding the Potential Impact of Different Drug Properties On SARS-CoV-2 Transmission and Disease Burden: A Modelling Analysis. Clin Infect Dis. 2021 Sep 21; doi: 10.1093/cid/ciab837. Epub 2021 Sep 21. PMID: 34549260.
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A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.

American journal of medical genetics. Part A

Lessel D, Rading K, Campbell SE, Thiele H, Altmüller J, Gordon LB, Kubisch C.
PMID: 34611991
Am J Med Genet A. 2021 Oct 05; doi: 10.1002/ajmg.a.62525. Epub 2021 Oct 05.

Pathogenic biallelic variants in POL3RA have been associated with different disorders characterized by progressive neurological deterioration. These include the 4H leukodystrophy syndrome (hypomyelination, hypogonadotropic hypogonadism, and hypodontia) and adolescent-onset progressive spastic ataxia, as well as Wiedemann-Rautenstrauch syndrome (WRS), a...

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Lessel D, Rading K, Campbell SE, et al. A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies. Am J Med Genet A. 2021;doi: 10.1002/ajmg.a.62525.
Lessel, D., Rading, K., Campbell, S. E., Thiele, H., Altmüller, J., Gordon, L. B., & Kubisch, C. (2021). A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies. American journal of medical genetics. Part A, . https://doi.org/10.1002/ajmg.a.62525
Lessel, Davor, et al. "A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies." American journal of medical genetics. Part A vol. (2021). doi: https://doi.org/10.1002/ajmg.a.62525
Lessel D, Rading K, Campbell SE, Thiele H, Altmüller J, Gordon LB, Kubisch C. A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies. Am J Med Genet A. 2021 Oct 05; doi: 10.1002/ajmg.a.62525. Epub 2021 Oct 05. PMID: 34611991.
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Platinized graphene fiber electrodes uncover direct spleen-vagus communication.

Communications biology

Gonzalez-Gonzalez MA, Bendale GS, Wang K, Wallace GG, Romero-Ortega M.
PMID: 34535751
Commun Biol. 2021 Sep 17;4(1):1097. doi: 10.1038/s42003-021-02628-7.

Neural interfacing nerve fascicles along the splenic neurovascular plexus (SNVP) is needed to better understand the spleen physiology, and for selective neuromodulation of this major organ. However, their small size and anatomical location have proven to be a significant...

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Gonzalez-Gonzalez MA, Bendale GS, Wang K, et al. Platinized graphene fiber electrodes uncover direct spleen-vagus communication. Commun Biol. 2021;4(1):1097doi: 10.1038/s42003-021-02628-7.
Gonzalez-Gonzalez, M. A., Bendale, G. S., Wang, K., Wallace, G. G., & Romero-Ortega, M. (2021). Platinized graphene fiber electrodes uncover direct spleen-vagus communication. Communications biology, 4(1), 1097. https://doi.org/10.1038/s42003-021-02628-7
Gonzalez-Gonzalez, Maria A, et al. "Platinized graphene fiber electrodes uncover direct spleen-vagus communication." Communications biology vol. 4,1 (2021): 1097. doi: https://doi.org/10.1038/s42003-021-02628-7
Gonzalez-Gonzalez MA, Bendale GS, Wang K, Wallace GG, Romero-Ortega M. Platinized graphene fiber electrodes uncover direct spleen-vagus communication. Commun Biol. 2021 Sep 17;4(1):1097. doi: 10.1038/s42003-021-02628-7. PMID: 34535751; PMCID: PMC8448843.
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Chronic Breast Pain Prior to Breast Cancer Surgery Is Associated with Worse Acute Postoperative Pain Outcomes.

Journal of clinical medicine

Raza MM, Zaslansky R, Gordon DB, Wildisen JM, Komann M, Stamer UM, Langford DJ.
PMID: 33925567
J Clin Med. 2021 Apr 27;10(9). doi: 10.3390/jcm10091887.

Acute postoperative pain is associated with adverse short and long-term outcomes among women undergoing surgery for breast cancer. Previous studies identified preexisting pain as a predictor of postoperative pain, but rarely accounted for pain location or chronicity. This study...

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Raza MM, Zaslansky R, Gordon DB, et al. Chronic Breast Pain Prior to Breast Cancer Surgery Is Associated with Worse Acute Postoperative Pain Outcomes. J Clin Med. 2021;10(9)doi: 10.3390/jcm10091887.
Raza, M. M., Zaslansky, R., Gordon, D. B., Wildisen, J. M., Komann, M., Stamer, U. M., & Langford, D. J. (2021). Chronic Breast Pain Prior to Breast Cancer Surgery Is Associated with Worse Acute Postoperative Pain Outcomes. Journal of clinical medicine, 10(9), . https://doi.org/10.3390/jcm10091887
Raza, Marium M, et al. "Chronic Breast Pain Prior to Breast Cancer Surgery Is Associated with Worse Acute Postoperative Pain Outcomes." Journal of clinical medicine vol. 10,9 (2021). doi: https://doi.org/10.3390/jcm10091887
Raza MM, Zaslansky R, Gordon DB, Wildisen JM, Komann M, Stamer UM, Langford DJ. Chronic Breast Pain Prior to Breast Cancer Surgery Is Associated with Worse Acute Postoperative Pain Outcomes. J Clin Med. 2021 Apr 27;10(9). doi: 10.3390/jcm10091887. PMID: 33925567; PMCID: PMC8123777.
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Bio-ink for on-demand printing of living cells.

Biomaterials science

Ferris CJ, Gilmore KJ, Beirne S, McCallum D, Wallace GG, In Het Panhuis M.
PMID: 32481802
Biomater Sci. 2013 Feb 03;1(2):224-230. doi: 10.1039/c2bm00114d. Epub 2012 Nov 05.

Drop-on-demand bioprinting allows the controlled placement of living cells, and will benefit research in the fields of tissue engineering, drug screening and toxicology. We show that a bio-ink based on a novel microgel suspension in a surfactant-containing tissue culture...

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Ferris CJ, Gilmore KJ, Beirne S, et al. Bio-ink for on-demand printing of living cells. Biomater Sci. 2012;1(2):224-230doi: 10.1039/c2bm00114d.
Ferris, C. J., Gilmore, K. J., Beirne, S., McCallum, D., Wallace, G. G., & In Het Panhuis, M. (2013). Bio-ink for on-demand printing of living cells. Biomaterials science, 1(2), 224-230. https://doi.org/10.1039/c2bm00114d
Ferris, Cameron J, et al. "Bio-ink for on-demand printing of living cells." Biomaterials science vol. 1,2 (2013): 224-230. doi: https://doi.org/10.1039/c2bm00114d
Ferris CJ, Gilmore KJ, Beirne S, McCallum D, Wallace GG, In Het Panhuis M. Bio-ink for on-demand printing of living cells. Biomater Sci. 2013 Feb 03;1(2):224-230. doi: 10.1039/c2bm00114d. Epub 2012 Nov 05. PMID: 32481802.
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Expression of Concern: Mechanisms underlying p53 regulation of .

Journal of cell science

Astanehe A, Arenillas D, Wasserman WW, Leung PCK, Dunn SE, Davies BR, Mills GB, Auersperg N.
PMID: 32917731
J Cell Sci. 2020 Sep 11;133(17). doi: 10.1242/jcs.253260.

No abstract available.

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Astanehe A, Arenillas D, Wasserman WW, et al. Expression of Concern: Mechanisms underlying p53 regulation of . J Cell Sci. 2020;133(17)doi: 10.1242/jcs.253260.
Astanehe, A., Arenillas, D., Wasserman, W. W., Leung, P. C. K., Dunn, S. E., Davies, B. R., Mills, G. B., & Auersperg, N. (2020). Expression of Concern: Mechanisms underlying p53 regulation of . Journal of cell science, 133(17), . https://doi.org/10.1242/jcs.253260
Astanehe, Arezoo, et al. "Expression of Concern: Mechanisms underlying p53 regulation of ." Journal of cell science vol. 133,17 (2020). doi: https://doi.org/10.1242/jcs.253260
Astanehe A, Arenillas D, Wasserman WW, Leung PCK, Dunn SE, Davies BR, Mills GB, Auersperg N. Expression of Concern: Mechanisms underlying p53 regulation of . J Cell Sci. 2020 Sep 11;133(17). doi: 10.1242/jcs.253260. PMID: 32917731.
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