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Showing 4105 to 4114 of 4114 entries
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Investigation into Small Molecule Isomeric Glucuronide Metabolite Differentiation Using .

Journal of the American Society for Mass Spectrometry

Connolly JRFB, Munoz-Muriedas J, Lapthorn C, Higton D, Vissers JPC, Webb A, Beaumont C, Dear GJ.
PMID: 34296869
J Am Soc Mass Spectrom. 2021 Aug 04;32(8):1976-1986. doi: 10.1021/jasms.0c00427. Epub 2021 Jul 23.

Identifying isomeric metabolites remains a challenging and time-consuming process with both sensitivity and unambiguous structural assignment typically only achieved through the combined use of LC-MS and NMR. Ion mobility mass spectrometry (IMMS) has the potential to produce timely and...

Large contribution to secondary organic aerosol from isoprene cloud chemistry.

Science advances

Lamkaddam H, Dommen J, Ranjithkumar A, Gordon H, Wehrle G, Krechmer J, Majluf F, Salionov D, Schmale J, Bjelić S, Carslaw KS, El Haddad I, Baltensperger U.
PMID: 33762335
Sci Adv. 2021 Mar 24;7(13). doi: 10.1126/sciadv.abe2952. Print 2021 Mar.

Aerosols still present the largest uncertainty in estimating anthropogenic radiative forcing. Cloud processing is potentially important for secondary organic aerosol (SOA) formation, a major aerosol component: however, laboratory experiments fail to mimic this process under atmospherically relevant conditions. We...

The Clinical Application of Circulating Tumor Cells and DNAs as Prognostic and Predictive Biomarkers in Gastrointestinal Cancer.

Current cancer drug targets

Memarpour S, Khalili-Tanha G, Ghannad AA, Razavi MS, Joudi M, Joodi M, Ferns GA, Hassanian SM, Khazaei M, Avan A.
PMID: 33719973
Curr Cancer Drug Targets. 2021;21(8):676-688. doi: 10.2174/1568009621666210311090531.

Gastrointestinal (GI) cancer is one of the most common cancers globally. Genetic and epigenetic mechanisms are involved in its pathogenesis. The conventional methods for diagnosis and screening for GI cancers are often invasive and have other limitations. In the...

A comparison of automated atrophy measures across the frontotemporal dementia spectrum: Implications for trials.

NeuroImage. Clinical

Gordon E, Bocchetta M, Nicholas J, Cash DM, Rohrer JD.
PMID: 34626889
Neuroimage Clin. 2021;32:102842. doi: 10.1016/j.nicl.2021.102842. Epub 2021 Oct 05.

BACKGROUND: Frontotemporal dementia (FTD) is a common cause of young onset dementia, and whilst there are currently no treatments, there are several promising candidates in development and early phase trials. Comprehensive investigations of neuroimaging markers of disease progression across...

Author Correction: PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma.

Nature communications

Ribas A, Algazi A, Ascierto PA, Butler MO, Chandra S, Gordon M, Hernandez-Aya L, Lawrence D, Lutzky J, Miller WH, Campbell KM, Delafont B, Marshall S, Mueller N, Robert C.
PMID: 34385448
Nat Commun. 2021 Aug 12;12(1):5022. doi: 10.1038/s41467-021-25285-0.

No abstract available.

A single-institution retrospective study of causes of prolonged prothrombin time and activated partial thromboplastin time in the outpatient setting.

International journal of laboratory hematology

Hazim AZ, Ruan GJ, Khodadadi RB, Slusser JP, Marshall AL, Pruthi RK.
PMID: 34612006
Int J Lab Hematol. 2022 Feb;44(1):209-215. doi: 10.1111/ijlh.13727. Epub 2021 Oct 05.

INTRODUCTION: An algorithmic approach, termed the prolonged clot time profile (PROCT), consisting of initial screening with prothrombin time (PT) and activated partial thromboplastin time (aPTT), reflexive mixing studies if indicated, and follow-up assays depending on initial testing results, offers...

Factors associated with physicians' choice of a career in research: a retrospective report 15 years after medical school graduation.

Krupat Edward, Camargo CarlosA, Strewler GordonJ, Espinola JaniceA, Fleenor ThomasJ, Dienstag JulesL.
UIID-AD: 3996
2017;5-15. doi: 10.1007/s10459-016-9678-5.

Relatively little is known regarding factors associated with the choice of a research career among practicing physicians, and most investigations of this issue have been conducted in the absence of a theoretical/conceptual model. Therefore we designed a survey to...

Education for Physician Clinical Researchers: Should One Size Fit All?.

Seely EllenW, Williams GordonH.
UIID-AD: 86
2010;3:8-9. doi: 10.1111/j.1752-8062.2009.00165.x.

No abstract available.

Factors associated with physicians' choice of a career in research: a retrospective report 15 years after medical school graduation.

Krupat Edward, Strewler GordonJ, Espinola JaniceA, Dienstag JulesL, Camargo CarlosA, Fleenor ThomasJ.
UIID-AD: 4641
2017;5-15.

Relatively little is known regarding factors associated with the choice of a research career among practicing physicians, and most investigations of this issue have been conducted in the absence of a theoretical/conceptual model. Therefore we designed a survey to...

The Vanishing Physician Scientist: A Critical Review and Analysis.

Gordon R.
UIID-AD: 229
2012;19:89-113. doi: 10.1080/08989621.2012.660076.

Review of the concept of "the vanishing physician-scientist" shows: 1) medical school admissions reject most students wanting medical research careers; 2) college years before medical school are the best time for students to begin research; 3) efforts to entice...

Showing 4105 to 4114 of 4114 entries