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A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products.

Chemical research in toxicology

Sleight TW, Sexton CN, Mpourmpakis G, Gilbertson LM, Ng CA.
PMID: 34662518
Chem Res Toxicol. 2021 Nov 15;34(11):2273-2286. doi: 10.1021/acs.chemrestox.1c00187. Epub 2021 Oct 18.

Polycyclic aromatic hydrocarbons (PAHs) are a complex group of environmental contaminants, many having long environmental half-lives. As these compounds degrade, the changes in their structure can result in a substantial increase in mutagenicity compared to the parent compound. Over...

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Sleight TW, Sexton CN, Mpourmpakis G, et al. A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products. Chem Res Toxicol. 2021;34(11):2273-2286doi: 10.1021/acs.chemrestox.1c00187.
Sleight, T. W., Sexton, C. N., Mpourmpakis, G., Gilbertson, L. M., & Ng, C. A. (2021). A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products. Chemical research in toxicology, 34(11), 2273-2286. https://doi.org/10.1021/acs.chemrestox.1c00187
Sleight, Trevor W, et al. "A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products." Chemical research in toxicology vol. 34,11 (2021): 2273-2286. doi: https://doi.org/10.1021/acs.chemrestox.1c00187
Sleight TW, Sexton CN, Mpourmpakis G, Gilbertson LM, Ng CA. A Classification Model to Identify Direct-Acting Mutagenic Polycyclic Aromatic Hydrocarbon Transformation Products. Chem Res Toxicol. 2021 Nov 15;34(11):2273-2286. doi: 10.1021/acs.chemrestox.1c00187. Epub 2021 Oct 18. PMID: 34662518.
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Self-stigma in people living with dementia in Chile: A qualitative exploratory study.

Aging & mental health

Gajardo J, Alvarado R, Slachevsky A, Gitlin LN.
PMID: 34772289
Aging Ment Health. 2021 Nov 12;1-8. doi: 10.1080/13607863.2021.1998351. Epub 2021 Nov 12.

BACKGROUND: Self-stigma is a dimension of stigma concerning how individuals internalize negative attributes and discriminate against their own selves. Dementia is a stigmatizing condition, and there is a paucity of research exploring the manifestations and implications of self- stigma...

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Gajardo J, Alvarado R, Slachevsky A, et al. Self-stigma in people living with dementia in Chile: A qualitative exploratory study. Aging Ment Health. 2021;1-8doi: 10.1080/13607863.2021.1998351.
Gajardo, J., Alvarado, R., Slachevsky, A., & Gitlin, L. N. (2021). Self-stigma in people living with dementia in Chile: A qualitative exploratory study. Aging & mental health, 1-8. https://doi.org/10.1080/13607863.2021.1998351
Gajardo, Jean, et al. "Self-stigma in people living with dementia in Chile: A qualitative exploratory study." Aging & mental health vol. (2021): 1-8. doi: https://doi.org/10.1080/13607863.2021.1998351
Gajardo J, Alvarado R, Slachevsky A, Gitlin LN. Self-stigma in people living with dementia in Chile: A qualitative exploratory study. Aging Ment Health. 2021 Nov 12;1-8. doi: 10.1080/13607863.2021.1998351. Epub 2021 Nov 12. PMID: 34772289.
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Patient Determinants for Histologic Diagnosis of NAFLD in the Real World: A TARGET-NASH Study.

Hepatology communications

Barritt AS, Watkins S, Gitlin N, Klein S, Lok AS, Loomba R, Schoen C, Reddy KR, Trinh HN, Mospan AR, Vos MB, Weiss LM, Cusi K, Neuschwander-Tetri BA, Sanyal AJ.
PMID: 34141981
Hepatol Commun. 2021 Feb 21;5(6):938-946. doi: 10.1002/hep4.1689. eCollection 2021 Jun.

Much of the current data on nonalcoholic fatty liver disease (NAFLD) are derived from biopsy-based studies that may introduce ascertainment and selection bias. Selection of patients for liver biopsy has implications for clinical practice and the reported epidemiology of...

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Barritt AS, Watkins S, Gitlin N, et al. Patient Determinants for Histologic Diagnosis of NAFLD in the Real World: A TARGET-NASH Study. Hepatol Commun. 2021;5(6):938-946doi: 10.1002/hep4.1689.
Barritt, A. S., Watkins, S., Gitlin, N., Klein, S., Lok, A. S., Loomba, R., Schoen, C., Reddy, K. R., Trinh, H. N., Mospan, A. R., Vos, M. B., Weiss, L. M., Cusi, K., Neuschwander-Tetri, B. A., & Sanyal, A. J. (2021). Patient Determinants for Histologic Diagnosis of NAFLD in the Real World: A TARGET-NASH Study. Hepatology communications, 5(6), 938-946. https://doi.org/10.1002/hep4.1689
Barritt, A Sidney, et al. "Patient Determinants for Histologic Diagnosis of NAFLD in the Real World: A TARGET-NASH Study." Hepatology communications vol. 5,6 (2021): 938-946. doi: https://doi.org/10.1002/hep4.1689
Barritt AS, Watkins S, Gitlin N, Klein S, Lok AS, Loomba R, Schoen C, Reddy KR, Trinh HN, Mospan AR, Vos MB, Weiss LM, Cusi K, Neuschwander-Tetri BA, Sanyal AJ. Patient Determinants for Histologic Diagnosis of NAFLD in the Real World: A TARGET-NASH Study. Hepatol Commun. 2021 Feb 21;5(6):938-946. doi: 10.1002/hep4.1689. eCollection 2021 Jun. PMID: 34141981; PMCID: PMC8183178.
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FOOT INJURIES IN MICHIGAN, USA, GRAY WOLVES (CANIS LUPUS), 1992-2014.

Journal of wildlife diseases

O'Brien DJ, Beyer DE, Largent E, Melotti JR, Ott-Conn CN, Lonsway DH, Cooley TM, Atkinson R, Clayson M, Straka KA.
PMID: 34797913
J Wildl Dis. 2021 Nov 19; doi: 10.7589/JWD-D-21-00022. Epub 2021 Nov 19.

The range of gray wolves (Canis lupus) in the contiguous United States is expanding. Research and monitoring to support population recovery and management often involves capture via foothold traps. A population-level epidemiologic assessment of the effect of trap injuries...

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O'Brien DJ, Beyer DE, Largent E, et al. FOOT INJURIES IN MICHIGAN, USA, GRAY WOLVES (CANIS LUPUS), 1992-2014. J Wildl Dis. 2021;doi: 10.7589/JWD-D-21-00022.
O'Brien, D. J., Beyer, D. E., Largent, E., Melotti, J. R., Ott-Conn, C. N., Lonsway, D. H., Cooley, T. M., Atkinson, R., Clayson, M., & Straka, K. A. (2021). FOOT INJURIES IN MICHIGAN, USA, GRAY WOLVES (CANIS LUPUS), 1992-2014. Journal of wildlife diseases, . https://doi.org/10.7589/JWD-D-21-00022
O'Brien, Daniel J, et al. "FOOT INJURIES IN MICHIGAN, USA, GRAY WOLVES (CANIS LUPUS), 1992-2014." Journal of wildlife diseases vol. (2021). doi: https://doi.org/10.7589/JWD-D-21-00022
O'Brien DJ, Beyer DE, Largent E, Melotti JR, Ott-Conn CN, Lonsway DH, Cooley TM, Atkinson R, Clayson M, Straka KA. FOOT INJURIES IN MICHIGAN, USA, GRAY WOLVES (CANIS LUPUS), 1992-2014. J Wildl Dis. 2021 Nov 19; doi: 10.7589/JWD-D-21-00022. Epub 2021 Nov 19. PMID: 34797913.
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Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme.

ChemMedChem

Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA.
PMID: 33686743
ChemMedChem. 2021 Jun 07;16(11):1775-1787. doi: 10.1002/cmdc.202100111. Epub 2021 Mar 31.

Insulin-degrading enzyme (IDE) is a human mononuclear Zn

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Adamek RN, Suire CN, Stokes RW, et al. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem. 2021;16(11):1775-1787doi: 10.1002/cmdc.202100111.
Adamek, R. N., Suire, C. N., Stokes, R. W., Brizuela, M. K., Cohen, S. M., & Leissring, M. A. (2021). Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem, 16(11), 1775-1787. https://doi.org/10.1002/cmdc.202100111
Adamek, Rebecca N, et al. "Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme." ChemMedChem vol. 16,11 (2021): 1775-1787. doi: https://doi.org/10.1002/cmdc.202100111
Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem. 2021 Jun 07;16(11):1775-1787. doi: 10.1002/cmdc.202100111. Epub 2021 Mar 31. PMID: 33686743; PMCID: PMC8627785.
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Controlling high blood pressure.

The American journal of nursing

Giblin E.
PMID: 247897
Am J Nurs. 1978 May;78(5):824. doi: 10.1097/00000446-197805000-00013.

No abstract available.

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Giblin E. Controlling high blood pressure. Am J Nurs. 1978;78(5):824doi: 10.1097/00000446-197805000-00013.
Giblin, E. (1978). Controlling high blood pressure. The American journal of nursing, 78(5), 824. https://doi.org/10.1097/00000446-197805000-00013
Giblin, E. "Controlling high blood pressure." The American journal of nursing vol. 78,5 (1978): 824. doi: https://doi.org/10.1097/00000446-197805000-00013
Giblin E. Controlling high blood pressure. Am J Nurs. 1978 May;78(5):824. doi: 10.1097/00000446-197805000-00013. PMID: 247897.
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Support for distracted driving laws: An analysis of adolescent drivers from the Traffic Safety Culture Index from 2011 to 2017.

Transportation research. Part F, Traffic psychology and behaviour

Pope CN, Nwosu A, Rudisill TM, Zhu M.
PMID: 34616221
Transp Res Part F Traffic Psychol Behav. 2021 Apr;78:424-432. doi: 10.1016/j.trf.2021.02.022. Epub 2021 Mar 26.

INTRODUCTION: Adolescent drivers are often the focus of traffic safety legislation as they are at increased risk for crash-related injury and death. However, the degree to which adolescents support distracted driving laws and factors contributing to their support are...

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Pope CN, Nwosu A, Rudisill TM, et al. Support for distracted driving laws: An analysis of adolescent drivers from the Traffic Safety Culture Index from 2011 to 2017. Transp Res Part F Traffic Psychol Behav. 2021;78:424-432doi: 10.1016/j.trf.2021.02.022.
Pope, C. N., Nwosu, A., Rudisill, T. M., & Zhu, M. (2021). Support for distracted driving laws: An analysis of adolescent drivers from the Traffic Safety Culture Index from 2011 to 2017. Transportation research. Part F, Traffic psychology and behaviour, 78424-432. https://doi.org/10.1016/j.trf.2021.02.022
Pope, Caitlin N, et al. "Support for distracted driving laws: An analysis of adolescent drivers from the Traffic Safety Culture Index from 2011 to 2017." Transportation research. Part F, Traffic psychology and behaviour vol. 78 (2021): 424-432. doi: https://doi.org/10.1016/j.trf.2021.02.022
Pope CN, Nwosu A, Rudisill TM, Zhu M. Support for distracted driving laws: An analysis of adolescent drivers from the Traffic Safety Culture Index from 2011 to 2017. Transp Res Part F Traffic Psychol Behav. 2021 Apr;78:424-432. doi: 10.1016/j.trf.2021.02.022. Epub 2021 Mar 26. PMID: 34616221; PMCID: PMC8489580.
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Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors.

Molecular therapy. Methods & clinical development

Werle AK, Powers TW, Zobel JF, Wappelhorst CN, Jarrold MF, Lyktey NA, Sloan CDK, Wolf AJ, Adams-Hall S, Baldus P, Runnels HA.
PMID: 34703846
Mol Ther Methods Clin Dev. 2021 Sep 01;23:254-262. doi: 10.1016/j.omtm.2021.08.009. eCollection 2021 Dec 10.

Adeno-associated virus (AAV) vectors, which contain a DNA transgene packaged into a protein capsid, have shown tremendous therapeutic potential in recent years. An inherent characteristic of the manufacturing process is production of empty capsids that lack the transgene and...

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Werle AK, Powers TW, Zobel JF, et al. Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors. Mol Ther Methods Clin Dev. 2021;23:254-262doi: 10.1016/j.omtm.2021.08.009.
Werle, A. K., Powers, T. W., Zobel, J. F., Wappelhorst, C. N., Jarrold, M. F., Lyktey, N. A., Sloan, C. D. K., Wolf, A. J., Adams-Hall, S., Baldus, P., & Runnels, H. A. (2021). Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors. Molecular therapy. Methods & clinical development, 23254-262. https://doi.org/10.1016/j.omtm.2021.08.009
Werle, Amanda K, et al. "Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors." Molecular therapy. Methods & clinical development vol. 23 (2021): 254-262. doi: https://doi.org/10.1016/j.omtm.2021.08.009
Werle AK, Powers TW, Zobel JF, Wappelhorst CN, Jarrold MF, Lyktey NA, Sloan CDK, Wolf AJ, Adams-Hall S, Baldus P, Runnels HA. Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors. Mol Ther Methods Clin Dev. 2021 Sep 01;23:254-262. doi: 10.1016/j.omtm.2021.08.009. eCollection 2021 Dec 10. PMID: 34703846; PMCID: PMC8505359.
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Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme.

ChemMedChem

Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA.
PMID: 33686743
ChemMedChem. 2021 Jun 07;16(11):1775-1787. doi: 10.1002/cmdc.202100111. Epub 2021 Mar 31.

Insulin-degrading enzyme (IDE) is a human mononuclear Zn

Cite
Adamek RN, Suire CN, Stokes RW, et al. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem. 2021;16(11):1775-1787doi: 10.1002/cmdc.202100111.
Adamek, R. N., Suire, C. N., Stokes, R. W., Brizuela, M. K., Cohen, S. M., & Leissring, M. A. (2021). Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem, 16(11), 1775-1787. https://doi.org/10.1002/cmdc.202100111
Adamek, Rebecca N, et al. "Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme." ChemMedChem vol. 16,11 (2021): 1775-1787. doi: https://doi.org/10.1002/cmdc.202100111
Adamek RN, Suire CN, Stokes RW, Brizuela MK, Cohen SM, Leissring MA. Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme. ChemMedChem. 2021 Jun 07;16(11):1775-1787. doi: 10.1002/cmdc.202100111. Epub 2021 Mar 31. PMID: 33686743; PMCID: PMC8627785.
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Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs.

Journal of animal science

Cadaret CN, Posont RJ, Swanson RM, Beard JK, Gibbs RL, Barnes TL, Marks-Nelson ES, Petersen JL, Yates DT.
PMID: 34865027
J Anim Sci. 2021 Dec 05; doi: 10.1093/jas/skab358. Epub 2021 Dec 05.

In humans and animals, intrauterine growth restriction (IUGR) results from fetal programming responses to poor intrauterine conditions. Chronic fetal hypoxemia elevates circulating catecholamines, which reduces skeletal muscle β2 adrenoceptor content and contributes to growth and metabolic pathologies in IUGR-born...

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Cadaret CN, Posont RJ, Swanson RM, et al. Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs. J Anim Sci. 2021;doi: 10.1093/jas/skab358.
Cadaret, C. N., Posont, R. J., Swanson, R. M., Beard, J. K., Gibbs, R. L., Barnes, T. L., Marks-Nelson, E. S., Petersen, J. L., & Yates, D. T. (2021). Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs. Journal of animal science, . https://doi.org/10.1093/jas/skab358
Cadaret, Caitlin N, et al. "Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs." Journal of animal science vol. (2021). doi: https://doi.org/10.1093/jas/skab358
Cadaret CN, Posont RJ, Swanson RM, Beard JK, Gibbs RL, Barnes TL, Marks-Nelson ES, Petersen JL, Yates DT. Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs. J Anim Sci. 2021 Dec 05; doi: 10.1093/jas/skab358. Epub 2021 Dec 05. PMID: 34865027.
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Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice.

The Journal of physiology

Chelette BM, Loeven AM, Gatlin DN, Landi Conde DR, Huffstetler CM, Qi M, Fadool DA.
PMID: 34807463
J Physiol. 2021 Nov 22; doi: 10.1113/JP282112. Epub 2021 Nov 22.

Excess nutrition causes loss of olfactory sensory neurons (OSNs) and reduces odour discrimination and odour perception in mice. To separate diet-induced obesity from the consumption of dietary fat, we designed pair-feeding experiments whereby mice were maintained on isocaloric diets...

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Chelette BM, Loeven AM, Gatlin DN, et al. Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice. J Physiol. 2021;doi: 10.1113/JP282112.
Chelette, B. M., Loeven, A. M., Gatlin, D. N., Landi Conde, D. R., Huffstetler, C. M., Qi, M., & Fadool, D. A. (2021). Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice. The Journal of physiology, . https://doi.org/10.1113/JP282112
Chelette, Brandon M, et al. "Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice." The Journal of physiology vol. (2021). doi: https://doi.org/10.1113/JP282112
Chelette BM, Loeven AM, Gatlin DN, Landi Conde DR, Huffstetler CM, Qi M, Fadool DA. Consumption of dietary fat causes loss of olfactory sensory neurons and associated circuitry that is not mitigated by voluntary exercise in mice. J Physiol. 2021 Nov 22; doi: 10.1113/JP282112. Epub 2021 Nov 22. PMID: 34807463.
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The role of endomyocardial biopsy in suspected myocarditis in the contemporary era: a 10-year National Transplant Centre experience.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology

Murphy L, McGuckin M, Giblin G, Keogh A, McGovern B, Fabre A, O'Neill J, Mahon N, Joyce E.
PMID: 34224863
Cardiovasc Pathol. 2021 Sep-Oct;54:107366. doi: 10.1016/j.carpath.2021.107366. Epub 2021 Jul 02.

BACKGROUND: Diagnostic endomyocardial biopsy (EMB) in patients with suspected myocarditis helps to direct therapy and guide prognosis. This study aimed to investigate the correlation between the 2007 clinical guideline indications for EMB and the presence of a diagnostic biopsy...

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Murphy L, McGuckin M, Giblin G, et al. The role of endomyocardial biopsy in suspected myocarditis in the contemporary era: a 10-year National Transplant Centre experience. Cardiovasc Pathol. 2021;54:107366doi: 10.1016/j.carpath.2021.107366.
Murphy, L., McGuckin, M., Giblin, G., Keogh, A., McGovern, B., Fabre, A., O'Neill, J., Mahon, N., & Joyce, E. (2021). The role of endomyocardial biopsy in suspected myocarditis in the contemporary era: a 10-year National Transplant Centre experience. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 54107366. https://doi.org/10.1016/j.carpath.2021.107366
Murphy, Laura, et al. "The role of endomyocardial biopsy in suspected myocarditis in the contemporary era: a 10-year National Transplant Centre experience." Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology vol. 54 (2021): 107366. doi: https://doi.org/10.1016/j.carpath.2021.107366
Murphy L, McGuckin M, Giblin G, Keogh A, McGovern B, Fabre A, O'Neill J, Mahon N, Joyce E. The role of endomyocardial biopsy in suspected myocarditis in the contemporary era: a 10-year National Transplant Centre experience. Cardiovasc Pathol. 2021 Sep-Oct;54:107366. doi: 10.1016/j.carpath.2021.107366. Epub 2021 Jul 02. PMID: 34224863.
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