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Showing 37 to 48 of 237 entries
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Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.

The Journal of clinical investigation

Godsel LM, Roth-Carter QR, Koetsier JL, Tsoi LC, Huffine AL, Broussard JA, Fitz GN, Lloyd SM, Kweon J, Burks HE, Hegazy M, Amagai S, Harms PW, Xing X, Kirma J, Johnson JL, Urciuoli G, Doglio LT, Swindell WR, Awatramani R, Sprecher E, Bao X, Cohen-Barak E, Missero C, Gudjonsson JE, Green KJ.
PMID: 34905516
J Clin Invest. 2021 Dec 14; doi: 10.1172/JCI144363. Epub 2021 Dec 14.

Desmoglein 1 (Dsg1) is a cadherin restricted to stratified tissues of terrestrial vertebrates, which serve as essential physical and immune barriers. Dsg1 loss-of-function mutations in humans result in skin lesions, multiple allergies, and isolated patient keratinocytes exhibit increased pro-allergic...

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Godsel LM, Roth-Carter QR, Koetsier JL, et al. Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor. J Clin Invest. 2021;doi: 10.1172/JCI144363.
Godsel, L. M., Roth-Carter, Q. R., Koetsier, J. L., Tsoi, L. C., Huffine, A. L., Broussard, J. A., Fitz, G. N., Lloyd, S. M., Kweon, J., Burks, H. E., Hegazy, M., Amagai, S., Harms, P. W., Xing, X., Kirma, J., Johnson, J. L., Urciuoli, G., Doglio, L. T., Swindell, W. R., Awatramani, R., Sprecher, E., Bao, X., Cohen-Barak, E., Missero, C., Gudjonsson, J. E., & Green, K. J. (2021). Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor. The Journal of clinical investigation, . https://doi.org/10.1172/JCI144363
Godsel, Lisa M, et al. "Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor." The Journal of clinical investigation vol. (2021). doi: https://doi.org/10.1172/JCI144363
Godsel LM, Roth-Carter QR, Koetsier JL, Tsoi LC, Huffine AL, Broussard JA, Fitz GN, Lloyd SM, Kweon J, Burks HE, Hegazy M, Amagai S, Harms PW, Xing X, Kirma J, Johnson JL, Urciuoli G, Doglio LT, Swindell WR, Awatramani R, Sprecher E, Bao X, Cohen-Barak E, Missero C, Gudjonsson JE, Green KJ. Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor. J Clin Invest. 2021 Dec 14; doi: 10.1172/JCI144363. Epub 2021 Dec 14. PMID: 34905516.
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Back to the Medicinal Chemistry Future.

Journal of medicinal chemistry

Giustiniano M, Gruber CW, Kent CN, Trippier PC.
PMID: 34719927
J Med Chem. 2021 Nov 11;64(21):15515-15518. doi: 10.1021/acs.jmedchem.1c01788. Epub 2021 Nov 01.

No abstract available.

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Giustiniano M, Gruber CW, Kent CN, et al. Back to the Medicinal Chemistry Future. J Med Chem. 2021;64(21):15515-15518doi: 10.1021/acs.jmedchem.1c01788.
Giustiniano, M., Gruber, C. W., Kent, C. N., & Trippier, P. C. (2021). Back to the Medicinal Chemistry Future. Journal of medicinal chemistry, 64(21), 15515-15518. https://doi.org/10.1021/acs.jmedchem.1c01788
Giustiniano, Mariateresa, et al. "Back to the Medicinal Chemistry Future." Journal of medicinal chemistry vol. 64,21 (2021): 15515-15518. doi: https://doi.org/10.1021/acs.jmedchem.1c01788
Giustiniano M, Gruber CW, Kent CN, Trippier PC. Back to the Medicinal Chemistry Future. J Med Chem. 2021 Nov 11;64(21):15515-15518. doi: 10.1021/acs.jmedchem.1c01788. Epub 2021 Nov 01. PMID: 34719927.
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Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies.

The Journal of nutrition

Pinart M, Jeran S, Boeing H, Stelmach-Mardas M, Standl M, Schulz H, Harris C, von Berg A, Herberth G, Koletzko S, Linseisen J, Breuninger TA, Nöthlings U, Barbaresko J, Benda S, Lachat C, Yang C, Gasparini P, Robino A, Rojo-Martínez G, Castaño L, Guillaume M, Donneau AF, Hoge A, Gillain N, Avraam D, Burton PR, Bouwman J, Pischon T, Nimptsch K.
PMID: 33847346
J Nutr. 2021 Aug 07;151(8):2317-2329. doi: 10.1093/jn/nxab077.

BACKGROUND: Associations between increased dietary fat and decreased carbohydrate intake with circulating HDL and non-HDL cholesterol have not been conclusively determined.OBJECTIVE: We assessed these relations in 8 European observational human studies participating in the European Nutritional Phenotype Assessment and...

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Pinart M, Jeran S, Boeing H, et al. Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies. J Nutr. 2021;151(8):2317-2329doi: 10.1093/jn/nxab077.
Pinart, M., Jeran, S., Boeing, H., Stelmach-Mardas, M., Standl, M., Schulz, H., Harris, C., von Berg, A., Herberth, G., Koletzko, S., Linseisen, J., Breuninger, T. A., Nöthlings, U., Barbaresko, J., Benda, S., Lachat, C., Yang, C., Gasparini, P., Robino, A., Rojo-Martínez, G., Castaño, L., Guillaume, M., Donneau, A. F., Hoge, A., Gillain, N., Avraam, D., Burton, P. R., Bouwman, J., Pischon, T., & Nimptsch, K. (2021). Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies. The Journal of nutrition, 151(8), 2317-2329. https://doi.org/10.1093/jn/nxab077
Pinart, Mariona, et al. "Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies." The Journal of nutrition vol. 151,8 (2021): 2317-2329. doi: https://doi.org/10.1093/jn/nxab077
Pinart M, Jeran S, Boeing H, Stelmach-Mardas M, Standl M, Schulz H, Harris C, von Berg A, Herberth G, Koletzko S, Linseisen J, Breuninger TA, Nöthlings U, Barbaresko J, Benda S, Lachat C, Yang C, Gasparini P, Robino A, Rojo-Martínez G, Castaño L, Guillaume M, Donneau AF, Hoge A, Gillain N, Avraam D, Burton PR, Bouwman J, Pischon T, Nimptsch K. Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies. J Nutr. 2021 Aug 07;151(8):2317-2329. doi: 10.1093/jn/nxab077. PMID: 33847346.
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Assistive devices caregivers use and find helpful to manage problem behaviors of dementia.

Gerontechnology : international journal on the fundamental aspects of technology to serve the ageing society

Gitlin LN, Winter L, Dennis MP.
PMID: 25429254
Gerontechnology. 2010;9(3):408-414. doi: 10.4017/gt.2010.09.03.006.00.

PURPOSE: Use of assistive devices in caring for individuals with dementia has not been systematically examined, particularly as it concerns managing behavioral symptoms. We tested a nonpharmacologic intervention to manage behaviors that involved instructing families in effective communication techniques,...

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Gitlin LN, Winter L, Dennis MP. Assistive devices caregivers use and find helpful to manage problem behaviors of dementia. Gerontechnology. 2010;9(3):408-414doi: 10.4017/gt.2010.09.03.006.00.
Gitlin, L. N., Winter, L., & Dennis, M. P. (2010). Assistive devices caregivers use and find helpful to manage problem behaviors of dementia. Gerontechnology : international journal on the fundamental aspects of technology to serve the ageing society, 9(3), 408-414. https://doi.org/10.4017/gt.2010.09.03.006.00
Gitlin, Laura N, et al. "Assistive devices caregivers use and find helpful to manage problem behaviors of dementia." Gerontechnology : international journal on the fundamental aspects of technology to serve the ageing society vol. 9,3 (2010): 408-414. doi: https://doi.org/10.4017/gt.2010.09.03.006.00
Gitlin LN, Winter L, Dennis MP. Assistive devices caregivers use and find helpful to manage problem behaviors of dementia. Gerontechnology. 2010;9(3):408-414. doi: 10.4017/gt.2010.09.03.006.00. PMID: 25429254; PMCID: PMC4241973.
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Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in sheep.

Translational animal science

Cadaret CN, Merrick EM, Barnes TL, Beede KA, Posont RJ, Petersen JL, Yates DT.
PMID: 30627702
Transl Anim Sci. 2018 Sep;2:S14-S18. doi: 10.1093/tas/txy047. Epub 2018 Sep 27.

No abstract available.

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Cadaret CN, Merrick EM, Barnes TL, et al. Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in sheep. Transl Anim Sci. 2018;2:S14-S18doi: 10.1093/tas/txy047.
Cadaret, C. N., Merrick, E. M., Barnes, T. L., Beede, K. A., Posont, R. J., Petersen, J. L., & Yates, D. T. (2018). Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in sheep. Translational animal science, 2S14-S18. https://doi.org/10.1093/tas/txy047
Cadaret, Caitlin N, et al. "Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in sheep." Translational animal science vol. 2 (2018): S14-S18. doi: https://doi.org/10.1093/tas/txy047
Cadaret CN, Merrick EM, Barnes TL, Beede KA, Posont RJ, Petersen JL, Yates DT. Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in sheep. Transl Anim Sci. 2018 Sep;2:S14-S18. doi: 10.1093/tas/txy047. Epub 2018 Sep 27. PMID: 30627702; PMCID: PMC6310366.
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Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid.

Translational animal science

Barnes TL, Beede KA, Merrick EM, Cadaret CN, Cupp AS, Yates DT.
PMID: 30627703
Transl Anim Sci. 2018 Sep;2:S27-S30. doi: 10.1093/tas/txy050. Epub 2018 Sep 27.

No abstract available.

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Barnes TL, Beede KA, Merrick EM, et al. Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid. Transl Anim Sci. 2018;2:S27-S30doi: 10.1093/tas/txy050.
Barnes, T. L., Beede, K. A., Merrick, E. M., Cadaret, C. N., Cupp, A. S., & Yates, D. T. (2018). Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid. Translational animal science, 2S27-S30. https://doi.org/10.1093/tas/txy050
Barnes, Taylor L, et al. "Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid." Translational animal science vol. 2 (2018): S27-S30. doi: https://doi.org/10.1093/tas/txy050
Barnes TL, Beede KA, Merrick EM, Cadaret CN, Cupp AS, Yates DT. Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid. Transl Anim Sci. 2018 Sep;2:S27-S30. doi: 10.1093/tas/txy050. Epub 2018 Sep 27. PMID: 30627703; PMCID: PMC6310365.
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Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia.

Journal of pain research

Kotecha M, Cheshire WP, Finnigan H, Giblin K, Naik H, Palmer J, Tate S, Zakrzewska JM.
PMID: 32669869
J Pain Res. 2020 Jul 01;13:1601-1609. doi: 10.2147/JPR.S247182. eCollection 2020.

PURPOSE: Vixotrigine (BIIB074) is a voltage- and use-dependent sodium channel blocker. These studies will evaluate the efficacy and safety of vixotrigine in treating pain experienced by patients with trigeminal neuralgia (TN) using enriched enrollment randomized withdrawal trial designs.PATIENTS AND...

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Kotecha M, Cheshire WP, Finnigan H, et al. Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia. J Pain Res. 2020;13:1601-1609doi: 10.2147/JPR.S247182.
Kotecha, M., Cheshire, W. P., Finnigan, H., Giblin, K., Naik, H., Palmer, J., Tate, S., & Zakrzewska, J. M. (2020). Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia. Journal of pain research, 131601-1609. https://doi.org/10.2147/JPR.S247182
Kotecha, Mona, et al. "Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia." Journal of pain research vol. 13 (2020): 1601-1609. doi: https://doi.org/10.2147/JPR.S247182
Kotecha M, Cheshire WP, Finnigan H, Giblin K, Naik H, Palmer J, Tate S, Zakrzewska JM. Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia. J Pain Res. 2020 Jul 01;13:1601-1609. doi: 10.2147/JPR.S247182. eCollection 2020. PMID: 32669869; PMCID: PMC7335847.
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Comprehensive home-based care coordination for vulnerable elders with dementia: Maximizing Independence at Home-Plus-Study protocol.

International journal of care coordination

Samus QM, Davis K, Willink A, Black BS, Reuland M, Leoutsakos J, Roth DL, Wolff J, Gitlin LN, Lyketsos CG, Johnston D.
PMID: 29607051
Int J Care Coord. 2017 Dec;20(4):123-134. doi: 10.1177/2053434517744071. Epub 2017 Dec 14.

INTRODUCTION: Despite availability of effective care strategies for dementia, most health care systems are not yet organized or equipped to provide comprehensive family-centered dementia care management. Maximizing Independence at Home-Plus is a promising new model of dementia care coordination...

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Samus QM, Davis K, Willink A, et al. Comprehensive home-based care coordination for vulnerable elders with dementia: Maximizing Independence at Home-Plus-Study protocol. Int J Care Coord. 2017;20(4):123-134doi: 10.1177/2053434517744071.
Samus, Q. M., Davis, K., Willink, A., Black, B. S., Reuland, M., Leoutsakos, J., Roth, D. L., Wolff, J., Gitlin, L. N., Lyketsos, C. G., & Johnston, D. (2017). Comprehensive home-based care coordination for vulnerable elders with dementia: Maximizing Independence at Home-Plus-Study protocol. International journal of care coordination, 20(4), 123-134. https://doi.org/10.1177/2053434517744071
Samus, Quincy M, et al. "Comprehensive home-based care coordination for vulnerable elders with dementia: Maximizing Independence at Home-Plus-Study protocol." International journal of care coordination vol. 20,4 (2017): 123-134. doi: https://doi.org/10.1177/2053434517744071
Samus QM, Davis K, Willink A, Black BS, Reuland M, Leoutsakos J, Roth DL, Wolff J, Gitlin LN, Lyketsos CG, Johnston D. Comprehensive home-based care coordination for vulnerable elders with dementia: Maximizing Independence at Home-Plus-Study protocol. Int J Care Coord. 2017 Dec;20(4):123-134. doi: 10.1177/2053434517744071. Epub 2017 Dec 14. PMID: 29607051; PMCID: PMC5870897.
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Development of an Enhanced Total Ion Current Chromatogram Algorithm to Improve Untargeted Peak Detection.

Analytical chemistry

Cain CN, Schöneich S, Synovec RE.
PMID: 32664728
Anal Chem. 2020 Aug 18;92(16):11365-11373. doi: 10.1021/acs.analchem.0c02136. Epub 2020 Jul 29.

Accurate analyte peak detection from the background noise is a fundamental step in data analysis. Often, this is initially performed on the total ion current chromatogram (TIC), which is the summed signal from all mass spectral channels. Despite the...

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Cain CN, Schöneich S, Synovec RE. Development of an Enhanced Total Ion Current Chromatogram Algorithm to Improve Untargeted Peak Detection. Anal Chem. 2020;92(16):11365-11373doi: 10.1021/acs.analchem.0c02136.
Cain, C. N., Schöneich, S., & Synovec, R. E. (2020). Development of an Enhanced Total Ion Current Chromatogram Algorithm to Improve Untargeted Peak Detection. Analytical chemistry, 92(16), 11365-11373. https://doi.org/10.1021/acs.analchem.0c02136
Cain, Caitlin N, et al. "Development of an Enhanced Total Ion Current Chromatogram Algorithm to Improve Untargeted Peak Detection." Analytical chemistry vol. 92,16 (2020): 11365-11373. doi: https://doi.org/10.1021/acs.analchem.0c02136
Cain CN, Schöneich S, Synovec RE. Development of an Enhanced Total Ion Current Chromatogram Algorithm to Improve Untargeted Peak Detection. Anal Chem. 2020 Aug 18;92(16):11365-11373. doi: 10.1021/acs.analchem.0c02136. Epub 2020 Jul 29. PMID: 32664728.
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Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review.

Ocular oncology and pathology

Balzer BWR, Cherepanoff S, Joshua AM, Giblin M, Conway RM, Anazodo AC.
PMID: 31768361
Ocul Oncol Pathol. 2019 Oct;5(6):387-395. doi: 10.1159/000497813. Epub 2019 Apr 10.

BACKGROUND: Conjunctival melanoma is rare in adults and rarer in children. We systematically reviewed the presentation, diagnostic and management strategies as well as outcomes for conjunctival melanoma in children and adolescents.METHODS: The following databases were searched: Medline, Embase, Web...

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Balzer BWR, Cherepanoff S, Joshua AM, et al. Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review. Ocul Oncol Pathol. 2019;5(6):387-395doi: 10.1159/000497813.
Balzer, B. W. R., Cherepanoff, S., Joshua, A. M., Giblin, M., Conway, R. M., & Anazodo, A. C. (2019). Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review. Ocular oncology and pathology, 5(6), 387-395. https://doi.org/10.1159/000497813
Balzer, Ben W R, et al. "Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review." Ocular oncology and pathology vol. 5,6 (2019): 387-395. doi: https://doi.org/10.1159/000497813
Balzer BWR, Cherepanoff S, Joshua AM, Giblin M, Conway RM, Anazodo AC. Conjunctival Melanoma in Childhood and Adolescence: A Systematic Review. Ocul Oncol Pathol. 2019 Oct;5(6):387-395. doi: 10.1159/000497813. Epub 2019 Apr 10. PMID: 31768361; PMCID: PMC6873081.
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Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age.

Translational animal science

Posont RJ, Cadaret CN, Beede KA, Beard JK, Swanson RM, Gibbs RL, Petersen JL, Yates DT.
PMID: 31867569
Transl Anim Sci. 2019 Dec;3:1673-1677. doi: 10.1093/tas/txz055. Epub 2019 Dec 16.

No abstract available.

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Posont RJ, Cadaret CN, Beede KA, et al. Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age. Transl Anim Sci. 2019;3:1673-1677doi: 10.1093/tas/txz055.
Posont, R. J., Cadaret, C. N., Beede, K. A., Beard, J. K., Swanson, R. M., Gibbs, R. L., Petersen, J. L., & Yates, D. T. (2019). Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age. Translational animal science, 31673-1677. https://doi.org/10.1093/tas/txz055
Posont, Robert J, et al. "Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age." Translational animal science vol. 3 (2019): 1673-1677. doi: https://doi.org/10.1093/tas/txz055
Posont RJ, Cadaret CN, Beede KA, Beard JK, Swanson RM, Gibbs RL, Petersen JL, Yates DT. Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age. Transl Anim Sci. 2019 Dec;3:1673-1677. doi: 10.1093/tas/txz055. Epub 2019 Dec 16. PMID: 31867569; PMCID: PMC6912171.
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Preliminary Outcomes of a Computerized CBT/MET Intervention for Depressed Cannabis Users in Psychiatry Care.

Cannabis (Research Society on Marijuana)

Glasner S, Kay-Lambkin F, Budney AJ, Gitlin M, Kagan B, Chokron-Garneau H, Ang A, Venegas A.
PMID: 31840135
Cannabis. 2018;1(2):36-47. doi: 10.26828/cannabis.2018.02.004. Epub 2018 Jul 07.

Although depression is common among cannabis users, there is a paucity of targeted interventions addressing depression and cannabis use disorders concurrently. In the present pilot study, we examine the feasibility, acceptability, and preliminary outcomes of a computer-assisted intervention combining...

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Glasner S, Kay-Lambkin F, Budney AJ, et al. Preliminary Outcomes of a Computerized CBT/MET Intervention for Depressed Cannabis Users in Psychiatry Care. Cannabis. 2018;1(2):36-47doi: 10.26828/cannabis.2018.02.004.
Glasner, S., Kay-Lambkin, F., Budney, A. J., Gitlin, M., Kagan, B., Chokron-Garneau, H., Ang, A., & Venegas, A. (2018). Preliminary Outcomes of a Computerized CBT/MET Intervention for Depressed Cannabis Users in Psychiatry Care. Cannabis (Research Society on Marijuana), 1(2), 36-47. https://doi.org/10.26828/cannabis.2018.02.004
Glasner, Suzette, et al. "Preliminary Outcomes of a Computerized CBT/MET Intervention for Depressed Cannabis Users in Psychiatry Care." Cannabis (Research Society on Marijuana) vol. 1,2 (2018): 36-47. doi: https://doi.org/10.26828/cannabis.2018.02.004
Glasner S, Kay-Lambkin F, Budney AJ, Gitlin M, Kagan B, Chokron-Garneau H, Ang A, Venegas A. Preliminary Outcomes of a Computerized CBT/MET Intervention for Depressed Cannabis Users in Psychiatry Care. Cannabis. 2018;1(2):36-47. doi: 10.26828/cannabis.2018.02.004. Epub 2018 Jul 07. PMID: 31840135; PMCID: PMC6910653.
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