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Showing 25 to 36 of 167 entries
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Early Initiation of Tocilizumab in Clinically Isolated Aortitis.

Cureus

Huang IJ, Pugh T, Liew J.
PMID: 31249756
Cureus. 2019 Apr 16;11(4):e4479. doi: 10.7759/cureus.4479.

Clinically isolated aortitis can arise from infectious or inflammatory etiologies. Glucocorticoids are the first-line therapy for inflammatory causes of aortitis such as large-vessel vasculitis. However, prolonged steroids use is associated with numerous side effects. We present a case of...

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.

Cell reports

Sheppard K, Gardin J, Sabnis GS, Peer A, Darrell M, Deats S, Geuther B, Lutz CM, Kumar V.
PMID: 35021077
Cell Rep. 2022 Jan 11;38(2):110231. doi: 10.1016/j.celrep.2021.110231.

Gait and posture are often perturbed in many neurological, neuromuscular, and neuropsychiatric conditions. Rodents provide a tractable model for elucidating disease mechanisms and interventions. Here, we develop a neural-network-based assay that adopts the commonly used open field apparatus for...

Approaching a New Normal: Lessons Learned Transitioning Family Education Programming to a Virtual Environment.

Health promotion practice

Corvin J, Nabours B, Bularca S, Haile A.
PMID: 34538109
Health Promot Pract. 2021 Sep 18;15248399211034814. doi: 10.1177/15248399211034814. Epub 2021 Sep 18.

The COVID-19 pandemic is highlighting deep-rooted health inequities. While the virus itself does not discriminate, gaps in access to services and disparities in health outcomes are prevalent. Concerns over worsening mental health outcomes and increases in family violence exist....

Developing Global Health Diplomacy-related Skills Using a COVID-19-like Epidemic Simulation as a Learning Strategy.

The American journal of tropical medicine and hygiene

Reina Ortiz M, Sharma V, Casanova J, Corvin J, Hoare I.
PMID: 33970889
Am J Trop Med Hyg. 2021 May 10; doi: 10.4269/ajtmh.21-0155. Epub 2021 May 10.

Public health and global health practitioners need to develop global health diplomacy (GHD) skills to efficiently work within complex global health scenarios, such as the current coronavirus disease (COVID-19) pandemic. Problem-based learning was used as a framework to create...

Carbonyl-Directed Aliphatic Fluorination: A Special Type of Hydrogen Atom Transfer Beats Out Norrish II.

Journal of the American Chemical Society

Ghorbani F, Harry SA, Capilato JN, Pitts CR, Joram J, Peters GN, Tovar JD, Smajlagic I, Siegler MA, Dudding T, Lectka T.
PMID: 32786786
J Am Chem Soc. 2020 Aug 26;142(34):14710-14724. doi: 10.1021/jacs.0c07004. Epub 2020 Aug 13.

Recently, our group reported that enone and ketone functional groups, upon photoexcitation, can direct site-selective sp

Computer-Based Stratified Primary Care for Musculoskeletal Consultations Compared With Usual Care: Study Protocol for the STarT MSK Cluster Randomized Controlled Trial.

JMIR research protocols

Hill J, Garvin S, Chen Y, Cooper V, Wathall S, Bartlam B, Saunders B, Lewis M, Protheroe J, Chudyk A, Birkinshaw H, Dunn KM, Jowett S, Oppong R, Hay E, van der Windt D, Mallen C, Foster NE.
PMID: 32442141
JMIR Res Protoc. 2020 Jul 05;9(7):e17939. doi: 10.2196/17939.

BACKGROUND: Musculoskeletal (MSK) pain is a major cause of pain and disability. We previously developed a prognostic tool (Start Back Tool) with demonstrated effectiveness in guiding primary care low back pain management by supporting decision making using matched treatments....

Erratum: Author Correction: Human-machine partnership with artificial intelligence for chest radiograph diagnosis.

NPJ digital medicine

Patel BN, Rosenberg L, Willcox G, Baltaxe D, Lyons M, Irvin J, Rajpurkar P, Amrhein T, Gupta R, Halabi S, Langlotz C, Lo E, Mammarappallil J, Mariano AJ, Riley G, Seekins J, Shen L, Zucker E, Lungren MP.
PMID: 31840097
NPJ Digit Med. 2019 Dec 10;2:129. doi: 10.1038/s41746-019-0198-6. eCollection 2019.

[This corrects the article DOI: 10.1038/s41746-019-0189-7.].

The Value of Voltage Histogram Analysis Derived Right Atrial Scar Burden in the Prediction of Left Atrial Scar Burden.

Cardiology research and practice

Herczeg S, Galvin J, Keaney JJ, Keelan E, Byrne R, Howard C, Geller L, Szeplaki G.
PMID: 32855820
Cardiol Res Pract. 2020 Aug 13;2020:3981684. doi: 10.1155/2020/3981684. eCollection 2020.

INTRODUCTION: Growing evidence suggests that fibrotic changes can be observed in atrial fibrillation (AF) in both atria. Quantification of the scar burden during electroanatomical mapping might have important therapeutic and prognostic consequences. However, as the current invasive treatment of...

PENet-a scalable deep-learning model for automated diagnosis of pulmonary embolism using volumetric CT imaging.

NPJ digital medicine

Huang SC, Kothari T, Banerjee I, Chute C, Ball RL, Borus N, Huang A, Patel BN, Rajpurkar P, Irvin J, Dunnmon J, Bledsoe J, Shpanskaya K, Dhaliwal A, Zamanian R, Ng AY, Lungren MP.
PMID: 32352039
NPJ Digit Med. 2020 Apr 24;3:61. doi: 10.1038/s41746-020-0266-y. eCollection 2020.

Pulmonary embolism (PE) is a life-threatening clinical problem and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Prompt diagnosis and immediate treatment are critical to avoid high morbidity and mortality rates, yet PE remains among the...

A broad-spectrum cloning vector that exists as both an integrated element and a free plasmid in Chlamydia trachomatis.

PloS one

Garvin L, Vande Voorde R, Dickinson M, Carrell S, Hybiske K, Rockey D.
PMID: 34914750
PLoS One. 2021 Dec 16;16(12):e0261088. doi: 10.1371/journal.pone.0261088. eCollection 2021.

Plasmid transformation of chlamydiae has created new opportunities to investigate host-microbe interactions during chlamydial infections; however, there are still limitations. Plasmid transformation requires a replicon derived from the native Chlamydia plasmid, and these transformations are species-specific. We explored the...

Morphogenesis of the human preimplantation embryo: bringing mechanics to the clinics.

Seminars in cell & developmental biology

Firmin J, Maître JL.
PMID: 34253437
Semin Cell Dev Biol. 2021 Dec;120:22-31. doi: 10.1016/j.semcdb.2021.07.005. Epub 2021 Jul 10.

During preimplantation development, the human embryo forms the blastocyst, the structure enabling uterine implantation. The blastocyst consists of an epithelial envelope, the trophectoderm, encompassing a fluid-filled lumen, the blastocoel, and a cluster of pluripotent stem cells, the inner cell...

Classification of Left Atrial Diseased Tissue Burden Determined by Automated Voltage Analysis Predicts Outcomes after Ablation for Atrial Fibrillation.

Disease markers

Herczeg S, Keaney JJ, Keelan E, Howard C, Walsh K, Geller L, Szeplaki G, Galvin J.
PMID: 34257744
Dis Markers. 2021 Jun 22;2021:5511267. doi: 10.1155/2021/5511267. eCollection 2021.

BACKGROUND: The burden and persistence of atrial fibrillation (AF) have been associated with the presence and extent of left atrial (LA) fibrosis. Recent reports have implicated an association between the extent of LA fibrosis and the outcome of pulmonary...

Showing 25 to 36 of 167 entries