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Showing 25 to 36 of 158 entries
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Coactivation pattern analysis reveals altered salience network dynamics in children with autism spectrum disorder.

Network neuroscience (Cambridge, Mass.)

Marshall E, Nomi JS, Dirks B, Romero C, Kupis L, Chang C, Uddin LQ.
PMID: 33409437
Netw Neurosci. 2020 Dec 01;4(4):1219-1234. doi: 10.1162/netn_a_00163. eCollection 2020.

Brain connectivity studies of autism spectrum disorder (ASD) have historically relied on static measures of functional connectivity. Recent work has focused on identifying transient configurations of brain activity, yet several open questions remain regarding the nature of specific brain...

Differentiating movement styles in professional tennis: A machine learning and hierarchical clustering approach.

European journal of sport science

Giles B, Peeling P, Kovalchik S, Reid M.
PMID: 34781856
Eur J Sport Sci. 2021 Dec 30;1-10. doi: 10.1080/17461391.2021.2006800. Epub 2021 Dec 30.

PURPOSE: Recent explorations of tennis-specific movements have developed contemporary methods for identifying and classifying changes of direction (COD) during match-play. The aim of this research was to employ these new analysis techniques to objectively explore individual nuance and style...

Evaluating Treatment Tolerability Using the Toxicity Index With Patient-Reported Outcomes Data.

Journal of pain and symptom management

Langlais B, Mazza GL, Thanarajasingam G, Rogak LJ, Ginos B, Heon N, Scher HI, Schwab G, Ganz PA, Basch E, Dueck AC.
PMID: 34371138
J Pain Symptom Manage. 2021 Aug 08; doi: 10.1016/j.jpainsymman.2021.07.031. Epub 2021 Aug 08.

CONTEXT: Summarizing longitudinal symptomatic adverse events during clinical trials is necessary for understanding treatment tolerability. The Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) provides insight for capturing treatment tolerability within trials. Tolerability summary measures,...

IMAGE-DRIVEN BIOPHYSICAL TUMOR GROWTH MODEL CALIBRATION.

SIAM journal on scientific computing : a publication of the Society for Industrial and Applied Mathematics

Scheufele K, Subramanian S, Mang A, Biros G, Mehl M.
PMID: 33071533
SIAM J Sci Comput. 2020;42(3):B549-B580. doi: 10.1137/19M1275280. Epub 2020 May 06.

We present a novel formulation for the calibration of a biophysical tumor growth model from a single-time snapshot, multiparametric magnetic resonance imaging (MRI) scan of a glioblastoma patient. Tumor growth models are typically nonlinear parabolic partial differential equations (PDEs)....

Advances in the use of electrospun nanofibrous polymeric matrix for dermal healing at the donor site after the split-thickness skin graft excision: a prospective, randomized, controlled, open-label, multicenter study.

Journal of burn care & research : official publication of the American Burn Association

Haik J, Ullman Y, Gur E, Ad-El D, Egozi D, Kruchevsky D, Zissman S, Biros E, Nir RR, Kornhaber R, Cleary M, Harats M.
PMID: 34751384
J Burn Care Res. 2021 Nov 09; doi: 10.1093/jbcr/irab216. Epub 2021 Nov 09.

Dressings used to manage donor site wounds have up to 40% of patients experiencing complications that may cause suboptimal scarring. We evaluated the efficacy and safety of a portable electrospun nanofibrous matrix that provides contactless management of donor site...

Validated biomarker assays confirm ARID1A loss is confounded with MMR deficiency, CD8 TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.

The Journal of pathology

Heinze K, Nazeran TM, Lee S, Krämer P, Cairns ES, Chiu DS, Leung SCY, Kang EY, Meagher NS, Kennedy CJ, Boros J, Kommoss F, Vollert HW, Heitze F, du Bois A, Harter P, Grube M, Kraemer B, Staebler A, Kommoss FKF, Heublein S, Sinn HP, Singh N, Laslavic A, Elishaev E, Olawaiye A, Moysich K, Modugno F, Sharma R, Brand AH, Harnett PR, DeFazio A, Fortner RT, Lubinski J, Lener M, Tołoczko-Grabarek A, Cybulski C, Gronwald H, Gronwald J, Coulson P, El-Bahrawy MA, Jones ME, Schoemaker MJ, Swerdlow AJ, Gorringe KL, Campbell I, Cook L, Gayther SA, Carney ME, Shvetsov YB, Hernandez BY, Wilkens LR, Goodman MT, Mateoiu C, Linder A, Sundfeldt K, Kelemen LE, Gentry-Maharaj A, Widschwendter M, Menon U, Bolton KL, Alsop J, Shah M, Jimenez-Linan M, Pharoah PDP, Brenton JD, Cushing-Haugen KL, Harris HR, Doherty JA, Gilks B, Ghatage P, Huntsman DG, Nelson GS, Tinker AV, Lee CH, Goode EL, Nelson BH, Ramus SJ, Kommoss S, Talhouk A, Köbel M, Anglesio MS.
PMID: 34897700
J Pathol. 2021 Dec 13; doi: 10.1002/path.5849. Epub 2021 Dec 13.

ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumour suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory reports on its relationship to outcome, immune response,...

l-lactate kinetics after abdominal aortic surgery and intestinal ischemia - An observational cohort study.

International journal of surgery (London, England)

Novotny T, Staffa R, Tomandl J, Krivka T, Slaby O, Kubicek L, Biros E, Tomandlova M, Vlachovsky R, Sponiar J, Radova L, Konieczna A.
PMID: 34999001
Int J Surg. 2022 Jan 05;106220. doi: 10.1016/j.ijsu.2021.106220. Epub 2022 Jan 05.

BACKGROUND: Postoperative intestinal ischemia is a severe complication in abdominal aortic surgery. Early diagnosis is needed for adequate and timely treatment. We studied the postoperative kinetics of l-lactate in vascular patients to assess its value as a marker for...

Mini-TrpRS is essential for IFNγ-induced monocyte-derived giant cell formation.

Cytokine

Biros E, Vangaveti V, Moran CS.
PMID: 33721618
Cytokine. 2021 Jun;142:155486. doi: 10.1016/j.cyto.2021.155486. Epub 2021 Mar 12.

Truncated tryptophanyl-tRNA synthetase (mini-TrpRS), like any other aminoacyl-tRNA synthetases, canonically functions as a protein synthesis enzyme. Here we provide evidence for an additional signaling role of mini-TrpRS in the formation of monocyte-derived multinuclear giant cells (MGCs). Interferon-gamma (IFNγ) readily...

Role of inflammatory cytokines in genesis and treatment of atherosclerosis.

Trends in cardiovascular medicine

Biros E, Reznik JE, Moran CS.
PMID: 33571665
Trends Cardiovasc Med. 2021 Feb 08; doi: 10.1016/j.tcm.2021.02.001. Epub 2021 Feb 08.

Atherosclerosis demonstrates an increased rate of vascular smooth muscle cells (VSMC) plasticity characterized by switching from the differentiated contractile phenotype to a de-differentiated synthetic state. In healthy blood vessels, phenotypic switching represents a fundamental property of VSMC in maintaining...

Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway.

Cell reports

Torosyan R, Huang S, Bommi PV, Tiwari R, An SY, Schonfeld M, Rajendran G, Kavanaugh MA, Gibbs B, Truax AD, Bohney S, Calcutt MW, Kerr EW, Leonardi R, Gao P, Chandel NS, Kapitsinou PP.
PMID: 34407414
Cell Rep. 2021 Aug 17;36(7):109547. doi: 10.1016/j.celrep.2021.109547.

Prolonged cellular hypoxia leads to energetic failure and death. However, sublethal hypoxia can trigger an adaptive response called hypoxic preconditioning. While prolyl-hydroxylase (PHD) enzymes and hypoxia-inducible factors (HIFs) have been identified as key elements of oxygen-sensing machinery, the mechanisms...

What really matters?: Educating academicians.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

Biros H.
PMID: 10230971
Acad Emerg Med. 1999 Apr;6(4):253-4. doi: 10.1111/j.1553-2712.1999.tb00382.x.

No abstract available.

The Center Problem for the Lotka Reactions with Generalized Mass-Action Kinetics.

Qualitative theory of dynamical systems

Boros B, Hofbauer J, Müller S, Regensburger G.
PMID: 30636938
Qual Theory Dyn Syst. 2018;17(2):403-410. doi: 10.1007/s12346-017-0243-2. Epub 2017 Jun 13.

Chemical reaction networks with generalized mass-action kinetics lead to power-law dynamical systems. As a simple example, we consider the Lotka reactions and the resulting planar ODE. We characterize the parameters (positive coefficients and real exponents) for which the unique...

Showing 25 to 36 of 158 entries