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Showing 25 to 36 of 218 entries
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Hydrogel-Based Slow Release of a Receptor-Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS-CoV-2.

Advanced materials (Deerfield Beach, Fla.)

Gale EC, Powell AE, Roth GA, Meany EL, Yan J, Ou BS, Grosskopf AK, Adamska J, Picece VCTM, d'Aquino AI, Pulendran B, Kim PS, Appel EA.
PMID: 34651342
Adv Mater. 2021 Oct 14;e2104362. doi: 10.1002/adma.202104362. Epub 2021 Oct 14.

The development of effective vaccines that can be rapidly manufactured and distributed worldwide is necessary to mitigate the devastating health and economic impacts of pandemics like COVID-19. The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein, which mediates host...

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Gale EC, Powell AE, Roth GA, et al. Hydrogel-Based Slow Release of a Receptor-Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS-CoV-2. Adv Mater. 2021;e2104362doi: 10.1002/adma.202104362.
Gale, E. C., Powell, A. E., Roth, G. A., Meany, E. L., Yan, J., Ou, B. S., Grosskopf, A. K., Adamska, J., Picece, V. C. T. M., d'Aquino, A. I., Pulendran, B., Kim, P. S., & Appel, E. A. (2021). Hydrogel-Based Slow Release of a Receptor-Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS-CoV-2. Advanced materials (Deerfield Beach, Fla.), e2104362. https://doi.org/10.1002/adma.202104362
Gale, Emily C, et al. "Hydrogel-Based Slow Release of a Receptor-Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS-CoV-2." Advanced materials (Deerfield Beach, Fla.) vol. (2021): e2104362. doi: https://doi.org/10.1002/adma.202104362
Gale EC, Powell AE, Roth GA, Meany EL, Yan J, Ou BS, Grosskopf AK, Adamska J, Picece VCTM, d'Aquino AI, Pulendran B, Kim PS, Appel EA. Hydrogel-Based Slow Release of a Receptor-Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS-CoV-2. Adv Mater. 2021 Oct 14;e2104362. doi: 10.1002/adma.202104362. Epub 2021 Oct 14. PMID: 34651342; PMCID: PMC8646307.
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Author response to: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures.

The British journal of surgery

Elliott JA, Kenyon R, Kelliher G, Gillis AE, Tierney S, Ridgway PF.
PMID: 33885729
Br J Surg. 2021 Jul 23;108(7):e250. doi: 10.1093/bjs/znab083.

No abstract available.

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Elliott JA, Kenyon R, Kelliher G, et al. Author response to: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures. Br J Surg. 2021;108(7):e250doi: 10.1093/bjs/znab083.
Elliott, J. A., Kenyon, R., Kelliher, G., Gillis, A. E., Tierney, S., & Ridgway, P. F. (2021). Author response to: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures. The British journal of surgery, 108(7), e250. https://doi.org/10.1093/bjs/znab083
Elliott, J A, et al. "Author response to: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures." The British journal of surgery vol. 108,7 (2021): e250. doi: https://doi.org/10.1093/bjs/znab083
Elliott JA, Kenyon R, Kelliher G, Gillis AE, Tierney S, Ridgway PF. Author response to: Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures. Br J Surg. 2021 Jul 23;108(7):e250. doi: 10.1093/bjs/znab083. PMID: 33885729; PMCID: PMC8083240.
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Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir.

Journal of neuro-oncology

Eltobgy M, Huntoon K, Musgrave N, Shaikhouni A, Hardesty DA, Giglio P, Elder JB.
PMID: 33860429
J Neurooncol. 2021 May;153(1):161-167. doi: 10.1007/s11060-021-03756-0. Epub 2021 Apr 15.

PURPOSE: Leptomeningeal carcinomatosis (LMC) is a form of CNS cancer metastasis with severe morbidity. Intrathecal chemotherapy (ITC) administration through an implanted ventricular catheter reservoir (IVCR) is often utilized. Additionally, a nuclear imaging flow study can be performed prior to...

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Eltobgy M, Huntoon K, Musgrave N, et al. Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir. J Neurooncol. 2021;153(1):161-167doi: 10.1007/s11060-021-03756-0.
Eltobgy, M., Huntoon, K., Musgrave, N., Shaikhouni, A., Hardesty, D. A., Giglio, P., & Elder, J. B. (2021). Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir. Journal of neuro-oncology, 153(1), 161-167. https://doi.org/10.1007/s11060-021-03756-0
Eltobgy, Mostafa, et al. "Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir." Journal of neuro-oncology vol. 153,1 (2021): 161-167. doi: https://doi.org/10.1007/s11060-021-03756-0
Eltobgy M, Huntoon K, Musgrave N, Shaikhouni A, Hardesty DA, Giglio P, Elder JB. Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir. J Neurooncol. 2021 May;153(1):161-167. doi: 10.1007/s11060-021-03756-0. Epub 2021 Apr 15. PMID: 33860429.
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Biopharma dealmaking in 2019.

Nature reviews. Drug discovery

Micklus A, Giglio P.
PMID: 32020070
Nat Rev Drug Discov. 2020 Feb;19(2):87-88. doi: 10.1038/d41573-020-00003-5.

No abstract available.

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Micklus A, Giglio P. Biopharma dealmaking in 2019. Nat Rev Drug Discov. 2020;19(2):87-88doi: 10.1038/d41573-020-00003-5.
Micklus, A., & Giglio, P. (2020). Biopharma dealmaking in 2019. Nature reviews. Drug discovery, 19(2), 87-88. https://doi.org/10.1038/d41573-020-00003-5
Micklus, Amanda, and Giglio, Patricia. "Biopharma dealmaking in 2019." Nature reviews. Drug discovery vol. 19,2 (2020): 87-88. doi: https://doi.org/10.1038/d41573-020-00003-5
Micklus A, Giglio P. Biopharma dealmaking in 2019. Nat Rev Drug Discov. 2020 Feb;19(2):87-88. doi: 10.1038/d41573-020-00003-5. PMID: 32020070.
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Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer.

Light, science & applications

Li HF, Liu XQ, Lyu C, Gorbaciova J, Wen LL, Shan GG, Wyatt PB, Ye HQ, Gillin WP.
PMID: 32194946
Light Sci Appl. 2020 Mar 04;9:32. doi: 10.1038/s41377-020-0266-3. eCollection 2020.

Advanced 1.5-µm emitting materials that can be used to fabricate electrically driven light-emitting devices have the potential for developing cost-effective light sources for integrated silicon photonics. Sensitized erbium (Er

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Li HF, Liu XQ, Lyu C, et al. Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer. Light Sci Appl. 2020;9:32doi: 10.1038/s41377-020-0266-3.
Li, H. F., Liu, X. Q., Lyu, C., Gorbaciova, J., Wen, L. L., Shan, G. G., Wyatt, P. B., Ye, H. Q., & Gillin, W. P. (2020). Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer. Light, science & applications, 932. https://doi.org/10.1038/s41377-020-0266-3
Li, Hong-Fei, et al. "Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer." Light, science & applications vol. 9 (2020): 32. doi: https://doi.org/10.1038/s41377-020-0266-3
Li HF, Liu XQ, Lyu C, Gorbaciova J, Wen LL, Shan GG, Wyatt PB, Ye HQ, Gillin WP. Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer. Light Sci Appl. 2020 Mar 04;9:32. doi: 10.1038/s41377-020-0266-3. eCollection 2020. PMID: 32194946; PMCID: PMC7054420.
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TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial .

Frontiers in physiology

Faienza F, Rizza S, Giglio P, Filomeni G.
PMID: 32411008
Front Physiol. 2020 Apr 29;11:340. doi: 10.3389/fphys.2020.00340. eCollection 2020.

No abstract available.

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Faienza F, Rizza S, Giglio P, et al. TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial . Front Physiol. 2020;11:340doi: 10.3389/fphys.2020.00340.
Faienza, F., Rizza, S., Giglio, P., & Filomeni, G. (2020). TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial . Frontiers in physiology, 11340. https://doi.org/10.3389/fphys.2020.00340
Faienza, Fiorella, et al. "TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial ." Frontiers in physiology vol. 11 (2020): 340. doi: https://doi.org/10.3389/fphys.2020.00340
Faienza F, Rizza S, Giglio P, Filomeni G. TRAP1: A Metabolic Hub Linking Aging Pathophysiology to Mitochondrial . Front Physiol. 2020 Apr 29;11:340. doi: 10.3389/fphys.2020.00340. eCollection 2020. PMID: 32411008; PMCID: PMC7201090.
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Experimental and theoretical progress in pipe flow transition.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Willis AP, Peixinho J, Kerswell RR, Mullin T.
PMID: 18487120
Philos Trans A Math Phys Eng Sci. 2008 Aug 13;366(1876):2671-84. doi: 10.1098/rsta.2008.0063.

There have been many investigations of the stability of Hagen-Poiseuille flow in the 125 years since Osborne Reynolds' famous experiments on the transition to turbulence in a pipe, and yet the pipe problem remains the focus of attention of...

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Willis AP, Peixinho J, Kerswell RR, et al. Experimental and theoretical progress in pipe flow transition. Philos Trans A Math Phys Eng Sci. 2008;366(1876):2671-84doi: 10.1098/rsta.2008.0063.
Willis, A. P., Peixinho, J., Kerswell, R. R., & Mullin, T. (2008). Experimental and theoretical progress in pipe flow transition. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 366(1876), 2671-84. https://doi.org/10.1098/rsta.2008.0063
Willis, A P, et al. "Experimental and theoretical progress in pipe flow transition." Philosophical transactions. Series A, Mathematical, physical, and engineering sciences vol. 366,1876 (2008): 2671-84. doi: https://doi.org/10.1098/rsta.2008.0063
Willis AP, Peixinho J, Kerswell RR, Mullin T. Experimental and theoretical progress in pipe flow transition. Philos Trans A Math Phys Eng Sci. 2008 Aug 13;366(1876):2671-84. doi: 10.1098/rsta.2008.0063. PMID: 18487120.
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Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge.

The Journal of surgical research

Mohanty S, Gillio A, Lindroth H, Ortiz D, Holler E, Azar J, Boustani M, Zarzaur B.
PMID: 34731730
J Surg Res. 2021 Oct 29;270:327-334. doi: 10.1016/j.jss.2021.08.043. Epub 2021 Oct 29.

BACKGROUND: Delirium is among the most common complications following major surgery. Delirium following medical illness is associated with the development of chronic cognitive decline. The objective of this study was to determine the association of postoperative delirium with dementia...

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Mohanty S, Gillio A, Lindroth H, et al. Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge. J Surg Res. 2021;270:327-334doi: 10.1016/j.jss.2021.08.043.
Mohanty, S., Gillio, A., Lindroth, H., Ortiz, D., Holler, E., Azar, J., Boustani, M., & Zarzaur, B. (2021). Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge. The Journal of surgical research, 270327-334. https://doi.org/10.1016/j.jss.2021.08.043
Mohanty, Sanjay, et al. "Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge." The Journal of surgical research vol. 270 (2021): 327-334. doi: https://doi.org/10.1016/j.jss.2021.08.043
Mohanty S, Gillio A, Lindroth H, Ortiz D, Holler E, Azar J, Boustani M, Zarzaur B. Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge. J Surg Res. 2021 Oct 29;270:327-334. doi: 10.1016/j.jss.2021.08.043. Epub 2021 Oct 29. PMID: 34731730.
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Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors: A Delphi study.

European journal of cancer (Oxford, England : 1990)

Da Silva Lopes AM, Colomer-Lahiguera S, Mederos Alfonso N, Aedo-Lopez V, Spurrier-Bernard G, Tolstrup LK, Pappot H, Aspeslagh S, Rogiers A, Neyns B, Haanen JB, Mitchell SA, Addeo A, Michielin O, Eicher M.
PMID: 34536946
Eur J Cancer. 2021 Nov;157:225-237. doi: 10.1016/j.ejca.2021.08.026. Epub 2021 Sep 15.

BACKGROUND: Immune-related adverse events (IrAEs) associated with the use of immune checkpoint inhibitors (ICIs) may not be fully covered by existing measures like the PRO-CTCAE™. Selecting PRO-CTCAE™ items for monitoring symptomatic adverse events is hindered by the heterogeneity and...

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Da Silva Lopes AM, Colomer-Lahiguera S, Mederos Alfonso N, et al. Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors: A Delphi study. Eur J Cancer. 2021;157:225-237doi: 10.1016/j.ejca.2021.08.026.
Da Silva Lopes, A. M., Colomer-Lahiguera, S., Mederos Alfonso, N., Aedo-Lopez, V., Spurrier-Bernard, G., Tolstrup, L. K., Pappot, H., Aspeslagh, S., Rogiers, A., Neyns, B., Haanen, J. B., Mitchell, S. A., Addeo, A., Michielin, O., & Eicher, M. (2021). Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors: A Delphi study. European journal of cancer (Oxford, England : 1990), 157225-237. https://doi.org/10.1016/j.ejca.2021.08.026
Da Silva Lopes, André Manuel, et al. "Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors: A Delphi study." European journal of cancer (Oxford, England : 1990) vol. 157 (2021): 225-237. doi: https://doi.org/10.1016/j.ejca.2021.08.026
Da Silva Lopes AM, Colomer-Lahiguera S, Mederos Alfonso N, Aedo-Lopez V, Spurrier-Bernard G, Tolstrup LK, Pappot H, Aspeslagh S, Rogiers A, Neyns B, Haanen JB, Mitchell SA, Addeo A, Michielin O, Eicher M. Patient-reported outcomes for monitoring symptomatic toxicities in cancer patients treated with immune-checkpoint inhibitors: A Delphi study. Eur J Cancer. 2021 Nov;157:225-237. doi: 10.1016/j.ejca.2021.08.026. Epub 2021 Sep 15. PMID: 34536946.
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The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention.

Obesity (Silver Spring, Md.)

Delahanty LM, Wadden TA, Goodwin PJ, Alfano CM, Thomson CA, Irwin ML, Neuhouser ML, Crane TE, Frank E, Spears PA, Gillis BP, Hershman DL, Paskett ED, Hopkins J, Bernstein V, Stearns V, White J, Hudis C, Winer EP, A Carey L, Partridge AH, Ligibel JA.
PMID: 34932888
Obesity (Silver Spring). 2022 Jan;30(1):28-38. doi: 10.1002/oby.23287.

The Breast Cancer Weight Loss (BWEL) trial is a randomized controlled trial designed to determine whether weight loss after a breast cancer diagnosis can reduce the risk of cancer recurrence in women with overweight or obesity. The BWEL trial...

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Delahanty LM, Wadden TA, Goodwin PJ, et al. The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention. Obesity (Silver Spring). 2022;30(1):28-38doi: 10.1002/oby.23287.
Delahanty, L. M., Wadden, T. A., Goodwin, P. J., Alfano, C. M., Thomson, C. A., Irwin, M. L., Neuhouser, M. L., Crane, T. E., Frank, E., Spears, P. A., Gillis, B. P., Hershman, D. L., Paskett, E. D., Hopkins, J., Bernstein, V., Stearns, V., White, J., Hudis, C., Winer, E. P., A Carey, L., Partridge, A. H., & Ligibel, J. A. (2022). The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention. Obesity (Silver Spring, Md.), 30(1), 28-38. https://doi.org/10.1002/oby.23287
Delahanty, Linda M, et al. "The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention." Obesity (Silver Spring, Md.) vol. 30,1 (2022): 28-38. doi: https://doi.org/10.1002/oby.23287
Delahanty LM, Wadden TA, Goodwin PJ, Alfano CM, Thomson CA, Irwin ML, Neuhouser ML, Crane TE, Frank E, Spears PA, Gillis BP, Hershman DL, Paskett ED, Hopkins J, Bernstein V, Stearns V, White J, Hudis C, Winer EP, A Carey L, Partridge AH, Ligibel JA. The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention. Obesity (Silver Spring). 2022 Jan;30(1):28-38. doi: 10.1002/oby.23287. PMID: 34932888.
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Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity.

ACS central science

Roth GA, Gale EC, Alcántara-Hernández M, Luo W, Axpe E, Verma R, Yin Q, Yu AC, Lopez Hernandez H, Maikawa CL, Smith AAA, Davis MM, Pulendran B, Idoyaga J, Appel EA.
PMID: 33145416
ACS Cent Sci. 2020 Oct 28;6(10):1800-1812. doi: 10.1021/acscentsci.0c00732. Epub 2020 Sep 16.

Vaccines aim to elicit a robust, yet targeted, immune response. Failure of a vaccine to elicit such a response arises in part from inappropriate temporal control over antigen and adjuvant presentation to the immune system. In this work, we...

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Roth GA, Gale EC, Alcántara-Hernández M, et al. Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity. ACS Cent Sci. 2020;6(10):1800-1812doi: 10.1021/acscentsci.0c00732.
Roth, G. A., Gale, E. C., Alcántara-Hernández, M., Luo, W., Axpe, E., Verma, R., Yin, Q., Yu, A. C., Lopez Hernandez, H., Maikawa, C. L., Smith, A. A. A., Davis, M. M., Pulendran, B., Idoyaga, J., & Appel, E. A. (2020). Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity. ACS central science, 6(10), 1800-1812. https://doi.org/10.1021/acscentsci.0c00732
Roth, Gillie A, et al. "Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity." ACS central science vol. 6,10 (2020): 1800-1812. doi: https://doi.org/10.1021/acscentsci.0c00732
Roth GA, Gale EC, Alcántara-Hernández M, Luo W, Axpe E, Verma R, Yin Q, Yu AC, Lopez Hernandez H, Maikawa CL, Smith AAA, Davis MM, Pulendran B, Idoyaga J, Appel EA. Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity. ACS Cent Sci. 2020 Oct 28;6(10):1800-1812. doi: 10.1021/acscentsci.0c00732. Epub 2020 Sep 16. PMID: 33145416; PMCID: PMC7596866.
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Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review.

Open medicine (Warsaw, Poland)

Boni A, Cochetti G, Sidoni A, Bellezza G, Lepri E, Giglio A, Turco M, Vermandois JAR, Zingaro MD, Cirocchi R, Mearini E.
PMID: 31410364
Open Med (Wars). 2019 Jul 31;14:443-455. doi: 10.1515/med-2019-0048. eCollection 2019.

PURPOSE: Angiosarcoma (AS) is an aggressive malignant tumour of endothelial origin, most frequently compelling the skin. The kidney is a rare site of primary occurrence of AS with a quite challenging diagnosis and poor prognosis, mainly due to its...

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Boni A, Cochetti G, Sidoni A, et al. Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review. Open Med (Wars). 2019;14:443-455doi: 10.1515/med-2019-0048.
Boni, A., Cochetti, G., Sidoni, A., Bellezza, G., Lepri, E., Giglio, A., Turco, M., Vermandois, J. A. R., Zingaro, M. D., Cirocchi, R., & Mearini, E. (2019). Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review. Open medicine (Warsaw, Poland), 14443-455. https://doi.org/10.1515/med-2019-0048
Boni, Andrea, et al. "Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review." Open medicine (Warsaw, Poland) vol. 14 (2019): 443-455. doi: https://doi.org/10.1515/med-2019-0048
Boni A, Cochetti G, Sidoni A, Bellezza G, Lepri E, Giglio A, Turco M, Vermandois JAR, Zingaro MD, Cirocchi R, Mearini E. Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review. Open Med (Wars). 2019 Jul 31;14:443-455. doi: 10.1515/med-2019-0048. eCollection 2019. PMID: 31410364; PMCID: PMC6689208.
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