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Showing 349 to 351 of 351 entries
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Gender-based differences in physician payments within the fee-for-service system in Ontario: a retrospective, cross-sectional study.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

Merali Z, Malhotra AK, Balas M, Lorello GR, Flexman A, Kiran T, Witiw CD.
PMID: 34663601
CMAJ. 2021 Oct 18;193(41):E1584-E1591. doi: 10.1503/cmaj.210437.

BACKGROUND: Differences in physician income by gender have been described in numerous jurisdictions, but few studies have looked at a Canadian cohort with adjustment for confounders. In this study, we aimed to understand differences in fee-for-service payments to men...

Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo.

Molecular therapy : the journal of the American Society of Gene Therapy

Aday S, Hazan-Halevy I, Chamorro-Jorganes A, Anwar M, Goldsmith M, Beazley-Long N, Sahoo S, Dogra N, Sweaad W, Catapano F, Ozaki-Tan S, Angelini GD, Madeddu P, Benest AV, Peer D, Emanueli C.
PMID: 33744469
Mol Ther. 2021 Jul 07;29(7):2239-2252. doi: 10.1016/j.ymthe.2021.03.015. Epub 2021 Mar 18.

MicroRNAs (miRNAs) regulate gene expression by post-transcriptional inhibition of target genes. Proangiogenic small extracellular vesicles (sEVs; popularly identified with the name "exosomes") with a composite cargo of miRNAs are secreted by cultured stem cells and present in human biological...

Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes.

Current opinion in structural biology

Malagrinò F, Diop A, Pagano L, Nardella C, Toto A, Gianni S.
PMID: 34902817
Curr Opin Struct Biol. 2021 Dec 10;72:153-160. doi: 10.1016/j.sbi.2021.11.004. Epub 2021 Dec 10.

Intrinsically disordered proteins (IDPs) can be generally described as a class of proteins that lack a well-defined ordered structure in isolation at physiological conditions. Upon binding to their physiological ligands, IDPs typically undergo a disorder-to-order transition, which may or...

Showing 349 to 351 of 351 entries