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Showing 13 to 24 of 249 entries
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Oxacalixarenes and oxacyclophanes containing 1,8-naphthyridines: a new class of molecular tweezers with concave-surface functionality.

Chemical communications (Cambridge, England)

Katz JL, Geller BJ, Foster PD.
PMID: 17325794
Chem Commun (Camb). 2007 Mar 14;(10):1026-8. doi: 10.1039/b615336d. Epub 2007 Feb 02.

The first examples of oxacalix[4]arenes and [1(4)]oxacyclophanes bearing 1,8-naphthyridine units are reported, and these systems function as molecular tweezers containing inner-cavity hydrogen bond acceptors.

The regulation of human P450c17 activity: relationship to premature adrenarche, insulin resistance and the polycystic ovary syndrome.

Trends in endocrinology and metabolism: TEM

Auchus RJ, Geller DH, Lee TC, Miller WL.
PMID: 18406239
Trends Endocrinol Metab. 1998 Feb;9(2):47-50. doi: 10.1016/s1043-2760(98)00016-2.

The polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and insulin resistance, but the connection between these two features has been unclear. Androgen synthesis is regulated in part by the ratio of the 17alpha-hydroxylase and 17,20 lyase activities of...

The changing presentation of choledochal cyst disease: an incidental diagnosis.

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery

Dhupar R, Gulack B, Geller DA, Marsh JW, Gamblin TC.
PMID: 19841688
HPB Surg. 2009;2009:103739. doi: 10.1155/2009/103739. Epub 2009 Oct 19.

BACKGROUND: Choledochal cysts are uncommon biliary lesions. Due to the evolution of imaging and laparoscopic surgery, we sought to describe our last 3 years experience with the presentation and management of choledochal cysts in adults.METHODS: A retrospective review of...

Cross-Regulation Between Wnt and NF-κB Signaling Pathways.

Forum on immunopathological diseases and therapeutics

Du Q, Geller DA.
PMID: 21686046
For Immunopathol Dis Therap. 2010;1(3):155-181. doi: 10.1615/ForumImmunDisTher.v1.i3.

Cross-regulation between the Wnt and nuclear factor (NF)-κB signaling pathways has emerged as an important area for the regulation of a diverse array of genes and pathways active in chronic inflammation, immunity, development, and tumorigenesis. The ligands, kinases, transcription...

A binary star fraction of 76 per cent and unusual orbit parameters for the blue stragglers of NGC 188.

Nature

Mathieu RD, Geller AM.
PMID: 20033042
Nature. 2009 Dec 24;462(7276):1032-5. doi: 10.1038/nature08568.

Blue straggler stars lie on or near the main sequences of star clusters (all members of which formed around the same time), but typically are more luminous than the turn-off stars and therefore long ago should have evolved off...

State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).

International journal of pediatric endocrinology

Geller DH, Pacaud D, Gordon CM, Misra M.
PMID: 21899727
Int J Pediatr Endocrinol. 2011 Aug 26;2011:9. doi: 10.1186/1687-9856-2011-9.

PCOS, a heterogeneous disorder characterized by cystic ovarian morphology, androgen excess, and/or irregular periods, emerges during or shortly after puberty. Peri- and post-pubertal obesity, insulin resistance and consequent hyperinsulinemia are highly prevalent co-morbidities of PCOS and promote an ongoing...

β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells.

Sarcoma

Piperdi S, Austin-Page L, Geller D, Ahluwalia M, Gorlick S, Gill J, Park A, Zhang W, Li N, Chung SH, Gorlick R.
PMID: 23125530
Sarcoma. 2012;2012:164803. doi: 10.1155/2012/164803. Epub 2012 Oct 18.

Although osteosarcoma is the most common primary malignant bone tumor in children and adolescents, its cell of origin and the genetic alterations are unclear. Previous studies have shown that serially introducing hTERT, SV40 large TAg, and H-Ras transforms human...

High-purity thermoacoustic isotope enrichment.

The Journal of the Acoustical Society of America

Swift GW, Geller DA, Backhaus SN.
PMID: 25096099
J Acoust Soc Am. 2014 Aug;136(2):638-48. doi: 10.1121/1.4887437.

In a tube many wavelengths long, thermoacoustic separation of a gas mixture can produce very high purities. A flexible wall allows a spatially continuous supply of acoustic power into such a long tube. Coiling the tube and immersing it...

Homology of assessment of visual function in human and animal models.

Environmental toxicology and pharmacology

Geller AM.
PMID: 21783516
Environ Toxicol Pharmacol. 2005 May;19(3):485-90. doi: 10.1016/j.etap.2004.12.011.

To connect animal models with human neurobehavioral evaluations, it is necessary to understand the level of homology present between tests administered across species. This paper identifies four different levels of homology of assessment based on identity of measurement, function,...

Transcatheter arterial chemoembolization is a feasible palliative locoregional therapy for breast cancer liver metastases.

International journal of surgical oncology

Cho SW, Kitisin K, Buck D, Steel J, Brufsky A, Gillespie R, Tsung A, Marsh JW, Geller DA, Gamblin TC.
PMID: 22312487
Int J Surg Oncol. 2010;2010:251621. doi: 10.1155/2010/251621. Epub 2010 Oct 28.

Background. Liver metastases are common in advanced breast cancer. We sought to evaluate the role of transcatheter arterial chemoembolization (TACE) in breast cancer patients with hepatic metastases. Methods. A retrospective review of ten patients with breast cancer who were...

Open-Wedge Valgus High Tibial Osteotomy Technique With Inverted L-Shaped Configuration.

Arthroscopy techniques

Monllau JC, Erquicia JI, Ibañez F, Ibañez M, Gelber PE, Masferrer-Pino A, Pelfort X.
PMID: 29349013
Arthrosc Tech. 2017 Nov 13;6(6):e2161-e2167. doi: 10.1016/j.eats.2017.08.009. eCollection 2017 Dec.

High tibial osteotomy (HTO) is a useful alternative in the treatment of symptomatic varus malalignment. However, among its drawbacks is the tendency to decrease patellar height and increase the posterior tibial slope. The increased tibial slope increases anterior cruciate...

Reconstruction of the Medial Patellofemoral Ligament.

Arthroscopy techniques

Monllau JC, Erquicia JI, Ibañez M, Gelber PE, Ibañez F, Masferrer-Pino A, Pelfort X.
PMID: 29354460
Arthrosc Tech. 2017 Sep 04;6(5):e1471-e1476. doi: 10.1016/j.eats.2017.06.039. eCollection 2017 Oct.

Patellar instability has been shown to be associated with different major factors. However, studies have demonstrated that soft tissue reconstructions are adequate enough to reestablish patellar constraint. In recent years, the medial patellofemoral ligament has been recognized as the...

Showing 13 to 24 of 249 entries