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Showing 9985 to 9996 of 25070 entries
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Atomically Dispersed High-Density Al-N.

Advanced materials (Deerfield Beach, Fla.)

Yang Q, Peng H, Zhang Q, Qian X, Chen X, Tang X, Dai S, Zhao J, Jiang K, Yang Q, Sun J, Zhang L, Zhang N, Gao H, Lu Z, Chen L.
PMID: 34536029
Adv Mater. 2021 Nov;33(45):e2103186. doi: 10.1002/adma.202103186. Epub 2021 Sep 18.

Highly active catalysts that can directly utilize renewable energy (e.g., solar energy) are desirable for CO

Amino Acid Reduction Can Help to Improve the Identification of Antimicrobial Peptides and Their Functional Activities.

Frontiers in genetics

Dong GF, Zheng L, Huang SH, Gao J, Zuo YC.
PMID: 33959153
Front Genet. 2021 Apr 20;12:669328. doi: 10.3389/fgene.2021.669328. eCollection 2021.

Antimicrobial peptides (AMPs) are considered as potential substitutes of antibiotics in the field of new anti-infective drug design. There have been several machine learning algorithms and web servers in identifying AMPs and their functional activities. However, there is still...

RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery.

Journal of controlled release : official journal of the Controlled Release Society

Ding Y, Lv B, Zheng J, Lu C, Liu J, Lei Y, Yang M, Wang Y, Li Z, Yang Y, Gong W, Han J, Gao C.
PMID: 34933051
J Control Release. 2021 Dec 18; doi: 10.1016/j.jconrel.2021.12.018. Epub 2021 Dec 18.

Hyper-inflammation associated with cytokine storm syndrome causes high mortality in patients with COVID-19. Glucocorticoids, such as methylprednisolone sodium succinate (MPSS), effectively inhibit this inflammatory response. However, frequent and chronic administration of glucocorticoids at high doses leads to hormone dependence...

Improved anticancer activity of betulinic acid on breast cancer through a grafted copolymer-based micelles system.

Drug delivery

Qi X, Gao C, Yin C, Fan J, Wu X, Guo C.
PMID: 34565273
Drug Deliv. 2021 Dec;28(1):1962-1971. doi: 10.1080/10717544.2021.1979125.

Betulinic acid (3β-Hydroxy-20(29)-lupaene-28-oic acid, BA) has excellent anti-cancer activity but poor solubility and low bioavailability. To improve the antitumor activity of BA, a polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (PVCL-PVA-PEG) graft copolymer (Soluplus) encapsulated BA micelle (Soluplus-BA) was fabricated. The Soluplus-BA...

Hydroplastic Micromolding of 2D Sheets.

Advanced materials (Deerfield Beach, Fla.)

Guo F, Wang Y, Jiang Y, Li Z, Xu Z, Zhao X, Guo T, Jiang W, Gao C.
PMID: 33988260
Adv Mater. 2021 Jun;33(25):e2008116. doi: 10.1002/adma.202008116. Epub 2021 May 14.

Processing 2D sheets into desired structures with high precision is of great importance for fabrication and application of their assemblies. Solution processing of 2D sheets from dilute dispersions is a commonly used method but offers limited control over feature...

Core-Symptom-Defined Cortical Gyrification Differences in Autism Spectrum Disorder.

Frontiers in psychiatry

Ning M, Li C, Gao L, Fan J.
PMID: 33959045
Front Psychiatry. 2021 Apr 20;12:619367. doi: 10.3389/fpsyt.2021.619367. eCollection 2021.

Autism spectrum disorder (ASD) is a heterogeneous disease that is characterized by abnormalities in social communication and interaction as well as repetitive behaviors and restricted interests. Structural brain imaging has identified significant cortical folding alterations in ASD; however, relatively...

Enantioselective γ-Addition-Driven Cascade of β,γ-Unsaturated Ketones by Ion-Pair Catalysis: Access to Chiral 1,3-Dioxolochroman Scaffolds.

Organic letters

Wang X, Zhou L, Zhang H, Ren X, Gao G, Wang T.
PMID: 34932357
Org Lett. 2021 Dec 21; doi: 10.1021/acs.orglett.1c03567. Epub 2021 Dec 21.

A highly enantioselective γ-addition-driven cascade of β,γ-unsaturated carbonyl compounds by bifunctional ion-pair catalysis has been developed. With this protocol, a range of functionalized chiral 1,3-dioxolochroman derivatives were prepared in high yields with superior stereoselectivities (>99%

Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes.

Journal of translational genetics and genomics

Moore A, Machiela MJ, Machado M, Wang SS, Kane E, Slager SL, Zhou W, Carrington M, Lan Q, Milne RL, Birmann BM, Adami HO, Albanes D, Arslan AA, Becker N, Benavente Y, Bisanzi S, Boffetta P, Bracci PM, Brennan P, Brooks-Wilson AR, Canzian F, Caporaso N, Clavel J, Cocco P, Conde L, Cox DG, Cozen W, Curtin K, De Vivo I, de Sanjose S, Foretova L, Gapstur SM, Ghesquières H, Giles GG, Glenn M, Glimelius B, Gao C, Habermann TM, Hjalgrim H, Jackson RD, Liebow M, Link BK, Maynadie M, McKay J, Melbye M, Miligi L, Molina TJ, Monnereau A, Nieters A, North KE, Offit K, Patel AV, Piro S, Ravichandran V, Riboli E, Salles G, Severson RK, Skibola CF, Smedby KE, Southey MC, Spinelli JJ, Staines A, Stewart C, Teras LR, Tinker LF, Travis RC, Vajdic CM, Vermeulen RCH, Vijai J, Weiderpass E, Weinstein S, Doo NW, Zhang Y, Zheng T, Chanock SJ, Rothman N, Cerhan JR, Dean M, Camp NJ, Yeager M, Berndt SI.
PMID: 34622145
J Transl Genet Genom. 2021;5:200-217. doi: 10.20517/jtgg.2021.08. Epub 2021 Jun 17.

AIM: Recessive genetic variation is thought to play a role in non-Hodgkin lymphoma (NHL) etiology. Runs of homozygosity (ROH), defined based on long, continuous segments of homozygous SNPs, can be used to estimate both measured and unmeasured recessive genetic...

Association Between Metabolic Syndrome and Peripheral Arterial Disease in Elderly Patients with Type 2 Diabetes.

Diabetes, metabolic syndrome and obesity : targets and therapy

Gao L, Zhao W, Liu Q, Qin M.
PMID: 34934333
Diabetes Metab Syndr Obes. 2021 Dec 14;14:4783-4789. doi: 10.2147/DMSO.S343441. eCollection 2021.

BACKGROUND: Peripheral artery disease (PAD) is a manifestation of atherosclerotic cardiovascular disease (ASCVD) and significantly increases the risk of myocardial infarction and stroke. As most patients with PAD are asymptomatic, this condition is largely neglected in clinical practice. Type...

A novel method of subxiphoid video-assisted thoracic surgery for thymectomy.

Annals of translational medicine

Gao L, Lu J, Shen Z, Chen H, Kang M.
PMID: 34532476
Ann Transl Med. 2021 Aug;9(16):1339. doi: 10.21037/atm-21-4070.

BACKGROUND: With advances in thoracoscopic surgical instruments and techniques, subxiphoid video-assisted thoracic surgery (S-VATS) has become the main approach for anterior mediastinal tumor resection under thoracoscopy. However, the drawbacks of S-VATS, including it being a relatively unfixed surgical procedure,...

Vascular characteristics and expression of hypoxia genes in Tibetan pigs' hearts.

Veterinary medicine and science

Yang Y, Gao C, Yang T, Sha Y, Cai Y, Wang X, Yang Q, Liu C, Wang B, Zhao S.
PMID: 34561963
Vet Med Sci. 2021 Sep 25; doi: 10.1002/vms3.639. Epub 2021 Sep 25.

BACKGROUND: Tibetan pigs have exhibited unique characteristics from low-altitudes pigs and adapted well to the Qinghai-Tibet Plateau.OBJECTIVES: The current study was undertaken to investigate the hypoxic adaptation of heart in Tibetan pigs.METHODS: The hearts of Tibetan pigs and Landrace...

Integrative Analysis of the Gut Microbiota and Metabolome for .

Journal of agricultural and food chemistry

Wan C, Wu K, Lu X, Fang F, Li Y, Zhao Y, Li S, Gao J.
PMID: 34889098
J Agric Food Chem. 2021 Dec 22;69(50):15414-15424. doi: 10.1021/acs.jafc.1c04259. Epub 2021 Dec 10.

This study aimed to find the best

Showing 9985 to 9996 of 25070 entries