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Showing 601 to 612 of 623 entries
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Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature.

International journal of nanomedicine

Yap KM, Sekar M, Fuloria S, Wu YS, Gan SH, Mat Rani NNI, Subramaniyan V, Kokare C, Lum PT, Begum MY, Mani S, Meenakshi DU, Sathasivam KV, Fuloria NK.
PMID: 34880614
Int J Nanomedicine. 2021 Dec 02;16:7891-7941. doi: 10.2147/IJN.S328135. eCollection 2021.

Despite recent advances in the diagnosis and treatment of breast cancer (BC), it remains a global health issue affecting millions of women annually. Poor prognosis in BC patients is often linked to drug resistance as well as the lack...

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Yap KM, Sekar M, Fuloria S, et al. Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature. Int J Nanomedicine. 2021;16:7891-7941doi: 10.2147/IJN.S328135.
Yap, K. M., Sekar, M., Fuloria, S., Wu, Y. S., Gan, S. H., Mat Rani, N. N. I., Subramaniyan, V., Kokare, C., Lum, P. T., Begum, M. Y., Mani, S., Meenakshi, D. U., Sathasivam, K. V., & Fuloria, N. K. (2021). Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature. International journal of nanomedicine, 167891-7941. https://doi.org/10.2147/IJN.S328135
Yap, Kah Min, et al. "Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature." International journal of nanomedicine vol. 16 (2021): 7891-7941. doi: https://doi.org/10.2147/IJN.S328135
Yap KM, Sekar M, Fuloria S, Wu YS, Gan SH, Mat Rani NNI, Subramaniyan V, Kokare C, Lum PT, Begum MY, Mani S, Meenakshi DU, Sathasivam KV, Fuloria NK. Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature. Int J Nanomedicine. 2021 Dec 02;16:7891-7941. doi: 10.2147/IJN.S328135. eCollection 2021. PMID: 34880614; PMCID: PMC8648329.
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A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns.

Diabetes, metabolic syndrome and obesity : targets and therapy

Zhou JH, Yu K, Ding H, Zhu ZH, Han LH, Zhang T.
PMID: 34234485
Diabetes Metab Syndr Obes. 2021 Jun 28;14:2879-2882. doi: 10.2147/DMSO.S290647. eCollection 2021.

OBJECTIVE: This study aimed to explore the impact of gestational diabetes mellitus (GDM) on the results of newborn hearing screening.METHODS: A total of 666 pregnant women who gave birth in the Obstetric Department of Sunshine Ronghe Hospital from August...

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Zhou JH, Yu K, Ding H, et al. A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns. Diabetes Metab Syndr Obes. 2021;14:2879-2882doi: 10.2147/DMSO.S290647.
Zhou, J. H., Yu, K., Ding, H., Zhu, Z. H., Han, L. H., & Zhang, T. (2021). A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns. Diabetes, metabolic syndrome and obesity : targets and therapy, 142879-2882. https://doi.org/10.2147/DMSO.S290647
Zhou, Jun-Hong, et al. "A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns." Diabetes, metabolic syndrome and obesity : targets and therapy vol. 14 (2021): 2879-2882. doi: https://doi.org/10.2147/DMSO.S290647
Zhou JH, Yu K, Ding H, Zhu ZH, Han LH, Zhang T. A Clinical Study on Gestational Diabetes Mellitus and the Hearing of Newborns. Diabetes Metab Syndr Obes. 2021 Jun 28;14:2879-2882. doi: 10.2147/DMSO.S290647. eCollection 2021. PMID: 34234485; PMCID: PMC8254026.
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Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy.

Scientific reports

Liang Y, Li Z, Yuan H, Wang L, Gao LH.
PMID: 33627737
Sci Rep. 2021 Feb 24;11(1):4449. doi: 10.1038/s41598-021-83931-5.

Glioblastoma is the most common primary brain cancer and it is nearly impossible to remove the entire tumor with surgery or a single drug. EGFRvIII is the most frequent genetic change associated with glioblastoma, so EGFRvIII-based targeting therapies provide...

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Liang Y, Li Z, Yuan H, et al. Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy. Sci Rep. 2021;11(1):4449doi: 10.1038/s41598-021-83931-5.
Liang, Y., Li, Z., Yuan, H., Wang, L., & Gao, L. H. (2021). Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy. Scientific reports, 11(1), 4449. https://doi.org/10.1038/s41598-021-83931-5
Liang, Yuchao, et al. "Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy." Scientific reports vol. 11,1 (2021): 4449. doi: https://doi.org/10.1038/s41598-021-83931-5
Liang Y, Li Z, Yuan H, Wang L, Gao LH. Poly(p-phenylenevinylene) nanoparticles modified with antiEGFRvIII for specific glioblastoma therapy. Sci Rep. 2021 Feb 24;11(1):4449. doi: 10.1038/s41598-021-83931-5. PMID: 33627737; PMCID: PMC7904835.
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Mental state of demoralisation across diverse clinical settings: A systematic review, meta-analysis and proposal for its use as a 'specifier' in mental illness.

The Australian and New Zealand journal of psychiatry

Gan LL, Gong S, Kissane DW.
PMID: 34879712
Aust N Z J Psychiatry. 2021 Dec 08;48674211060746. doi: 10.1177/00048674211060746. Epub 2021 Dec 08.

OBJECTIVE: Demoralisation is a state of poor coping characterised by low morale, hopelessness, subjective incompetence, and loss of meaning and purpose in life. While studied extensively in oncology and palliative care, there has been recent exploration in broader medical...

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Gan LL, Gong S, Kissane DW. Mental state of demoralisation across diverse clinical settings: A systematic review, meta-analysis and proposal for its use as a 'specifier' in mental illness. Aust N Z J Psychiatry. 2021;48674211060746doi: 10.1177/00048674211060746.
Gan, L. L., Gong, S., & Kissane, D. W. (2021). Mental state of demoralisation across diverse clinical settings: A systematic review, meta-analysis and proposal for its use as a 'specifier' in mental illness. The Australian and New Zealand journal of psychiatry, 48674211060746. https://doi.org/10.1177/00048674211060746
Gan, Lucy L, et al. "Mental state of demoralisation across diverse clinical settings: A systematic review, meta-analysis and proposal for its use as a 'specifier' in mental illness." The Australian and New Zealand journal of psychiatry vol. (2021): 48674211060746. doi: https://doi.org/10.1177/00048674211060746
Gan LL, Gong S, Kissane DW. Mental state of demoralisation across diverse clinical settings: A systematic review, meta-analysis and proposal for its use as a 'specifier' in mental illness. Aust N Z J Psychiatry. 2021 Dec 08;48674211060746. doi: 10.1177/00048674211060746. Epub 2021 Dec 08. PMID: 34879712.
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Aptamer-based biosensors and application in tumor theranostics.

Cancer science

Mo T, Liu X, Luo Y, Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P, Chen X.
PMID: 34747552
Cancer Sci. 2022 Jan;113(1):7-16. doi: 10.1111/cas.15194. Epub 2021 Nov 16.

An aptamer is a short oligonucleotide chain that can specifically recognize targeting analytes. Due to its high specificity, low cost, and good biocompatibility, aptamers as the targeting elements of biosensors have been applied widely in non-invasive tumor imaging and...

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Mo T, Liu X, Luo Y, et al. Aptamer-based biosensors and application in tumor theranostics. Cancer Sci. 2021;113(1):7-16doi: 10.1111/cas.15194.
Mo, T., Liu, X., Luo, Y., Zhong, L., Zhang, Z., Li, T., Gan, L., Liu, X., Li, L., Wang, H., Sun, X., Fan, D., Qian, Z., Wu, P., & Chen, X. (2022). Aptamer-based biosensors and application in tumor theranostics. Cancer science, 113(1), 7-16. https://doi.org/10.1111/cas.15194
Mo, Tong, et al. "Aptamer-based biosensors and application in tumor theranostics." Cancer science vol. 113,1 (2022): 7-16. doi: https://doi.org/10.1111/cas.15194
Mo T, Liu X, Luo Y, Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P, Chen X. Aptamer-based biosensors and application in tumor theranostics. Cancer Sci. 2022 Jan;113(1):7-16. doi: 10.1111/cas.15194. Epub 2021 Nov 16. PMID: 34747552.
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Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway.

Bioorganic chemistry

Li S, Gan L, Tian YJ, Tian Y, Fan RZ, Huang D, Yuan FY, Zhang X, Lin Y, Zhu QF, Tang GH, Yan XL, Yin S.
PMID: 34375196
Bioorg Chem. 2021 Sep;114:105222. doi: 10.1016/j.bioorg.2021.105222. Epub 2021 Jul 28.

Seven new diterpenoids, eupholenes A-G (1-7), including two presegetanes (1 and 2), four jatrophanes (3-6), and one paraliane (7), along with 19 known analogues (8-26) were obtained by anti-liver fibrosis bioassay-guided isolation of Euphorbia sieboldiana. Their structures were elucidated...

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Li S, Gan L, Tian YJ, et al. Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway. Bioorg Chem. 2021;114:105222doi: 10.1016/j.bioorg.2021.105222.
Li, S., Gan, L., Tian, Y. J., Tian, Y., Fan, R. Z., Huang, D., Yuan, F. Y., Zhang, X., Lin, Y., Zhu, Q. F., Tang, G. H., Yan, X. L., & Yin, S. (2021). Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway. Bioorganic chemistry, 114105222. https://doi.org/10.1016/j.bioorg.2021.105222
Li, Shen, et al. "Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway." Bioorganic chemistry vol. 114 (2021): 105222. doi: https://doi.org/10.1016/j.bioorg.2021.105222
Li S, Gan L, Tian YJ, Tian Y, Fan RZ, Huang D, Yuan FY, Zhang X, Lin Y, Zhu QF, Tang GH, Yan XL, Yin S. Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway. Bioorg Chem. 2021 Sep;114:105222. doi: 10.1016/j.bioorg.2021.105222. Epub 2021 Jul 28. PMID: 34375196.
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Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats.

Journal of Alzheimer's disease reports

Gan L, Wan X, Ma D, Yang FC, Zhu J, Rogers RS, Wheatley JL, Koch LG, Britton SL, Thyfault JP, Geiger PC, Stanford JA.
PMID: 34368631
J Alzheimers Dis Rep. 2021 Jun 08;5(1):469-475. doi: 10.3233/ADR-200289. eCollection 2021.

BACKGROUND: Aerobic capacity is associated with metabolic, cardiovascular, and neurological health. Low-capacity runner (LCR) rats display low aerobic capacity, metabolic dysfuction, and spatial memory deficits. A heat treatment (HT) can improve metabolic dysfunction in LCR peripheral organs after high...

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Gan L, Wan X, Ma D, et al. Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats. J Alzheimers Dis Rep. 2021;5(1):469-475doi: 10.3233/ADR-200289.
Gan, L., Wan, X., Ma, D., Yang, F. C., Zhu, J., Rogers, R. S., Wheatley, J. L., Koch, L. G., Britton, S. L., Thyfault, J. P., Geiger, P. C., & Stanford, J. A. (2021). Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats. Journal of Alzheimer's disease reports, 5(1), 469-475. https://doi.org/10.3233/ADR-200289
Gan, Li, et al. "Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats." Journal of Alzheimer's disease reports vol. 5,1 (2021): 469-475. doi: https://doi.org/10.3233/ADR-200289
Gan L, Wan X, Ma D, Yang FC, Zhu J, Rogers RS, Wheatley JL, Koch LG, Britton SL, Thyfault JP, Geiger PC, Stanford JA. Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats. J Alzheimers Dis Rep. 2021 Jun 08;5(1):469-475. doi: 10.3233/ADR-200289. eCollection 2021. PMID: 34368631; PMCID: PMC8293662.
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New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia.

Current opinion in neurobiology

Amin S, Carling G, Gan L.
PMID: 34826653
Curr Opin Neurobiol. 2021 Nov 23;72:131-139. doi: 10.1016/j.conb.2021.10.001. Epub 2021 Nov 23.

Frontotemporal dementia (FTD) is the second most common form of dementia. It affects the frontal and temporal lobes of the brain and has a highly heterogeneous clinical representation with patients presenting with a wide range of behavioral, language, and...

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Amin S, Carling G, Gan L. New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia. Curr Opin Neurobiol. 2021;72:131-139doi: 10.1016/j.conb.2021.10.001.
Amin, S., Carling, G., & Gan, L. (2021). New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia. Current opinion in neurobiology, 72131-139. https://doi.org/10.1016/j.conb.2021.10.001
Amin, Sadaf, et al. "New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia." Current opinion in neurobiology vol. 72 (2021): 131-139. doi: https://doi.org/10.1016/j.conb.2021.10.001
Amin S, Carling G, Gan L. New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia. Curr Opin Neurobiol. 2021 Nov 23;72:131-139. doi: 10.1016/j.conb.2021.10.001. Epub 2021 Nov 23. PMID: 34826653.
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Developing Proton-Conductive Metal Coordination Polymer as Highly Efficient Electrocatalyst toward Oxygen Reduction.

The journal of physical chemistry letters

Huang X, Gan LY, Wang J, Ali S, He CC, Xu H.
PMID: 34528786
J Phys Chem Lett. 2021 Sep 30;12(38):9197-9204. doi: 10.1021/acs.jpclett.1c02665. Epub 2021 Sep 16.

Developing earth-abundant transition metal (TM)-based electrocatalysts toward oxygen reduction reaction (ORR) is significant in overcoming the high cost of fuel cells. Herein, using an as-synthesized proton-conductive coordination polymer (termed TM-DHBQ) as a template, we investigate the ORR performance of...

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Huang X, Gan LY, Wang J, et al. Developing Proton-Conductive Metal Coordination Polymer as Highly Efficient Electrocatalyst toward Oxygen Reduction. J Phys Chem Lett. 2021;12(38):9197-9204doi: 10.1021/acs.jpclett.1c02665.
Huang, X., Gan, L. Y., Wang, J., Ali, S., He, C. C., & Xu, H. (2021). Developing Proton-Conductive Metal Coordination Polymer as Highly Efficient Electrocatalyst toward Oxygen Reduction. The journal of physical chemistry letters, 12(38), 9197-9204. https://doi.org/10.1021/acs.jpclett.1c02665
Huang, Xiang, et al. "Developing Proton-Conductive Metal Coordination Polymer as Highly Efficient Electrocatalyst toward Oxygen Reduction." The journal of physical chemistry letters vol. 12,38 (2021): 9197-9204. doi: https://doi.org/10.1021/acs.jpclett.1c02665
Huang X, Gan LY, Wang J, Ali S, He CC, Xu H. Developing Proton-Conductive Metal Coordination Polymer as Highly Efficient Electrocatalyst toward Oxygen Reduction. J Phys Chem Lett. 2021 Sep 30;12(38):9197-9204. doi: 10.1021/acs.jpclett.1c02665. Epub 2021 Sep 16. PMID: 34528786.
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Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery.

Biosensors & bioelectronics

Gan L, Loke FWL, Cheong WC, Ng JSH, Tan NC, Zhu Z.
PMID: 33979719
Biosens Bioelectron. 2021 Apr 30;186:113283. doi: 10.1016/j.bios.2021.113283. Epub 2021 Apr 30.

We reported a proof-of-concept study of developing an electrochemical biosensor for prolonged continuous monitoring free flap failure caused by vascular occlusion after reconstructive surgery. Ferrocene (Fc)-containing Chitosan-cografted-Branched Polyethylenimine redox conjugates (CHIT-Fc-co-BPEI-Fc) were used as pH-tuneable matrix to attach the...

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Gan L, Loke FWL, Cheong WC, et al. Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery. Biosens Bioelectron. 2021;186:113283doi: 10.1016/j.bios.2021.113283.
Gan, L., Loke, F. W. L., Cheong, W. C., Ng, J. S. H., Tan, N. C., & Zhu, Z. (2021). Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery. Biosensors & bioelectronics, 186113283. https://doi.org/10.1016/j.bios.2021.113283
Gan, Lu, et al. "Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery." Biosensors & bioelectronics vol. 186 (2021): 113283. doi: https://doi.org/10.1016/j.bios.2021.113283
Gan L, Loke FWL, Cheong WC, Ng JSH, Tan NC, Zhu Z. Design and development of ferrocene-containing chitosan-cografted-branched polyethylenimine redox conjugates for monitoring free flap failure after reconstructive surgery. Biosens Bioelectron. 2021 Apr 30;186:113283. doi: 10.1016/j.bios.2021.113283. Epub 2021 Apr 30. PMID: 33979719.
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Drug-Drug Interactions of Newly Approved Direct-Acting Antiviral Agents in Patients with Hepatitis C.

International journal of general medicine

Gao LH, Nie QH, Zhao XT.
PMID: 33536776
Int J Gen Med. 2021 Jan 28;14:289-301. doi: 10.2147/IJGM.S283910. eCollection 2021.

Hepatitis C is a major health problem worldwide, frequently resulting in cirrhosis and increasing the risk of hepatocellular carcinoma significantly. In recent years, the advent of direct-acting antivirals (DAAs) has dramatically improved the therapeutic outcomes in hepatitis C patients....

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Gao LH, Nie QH, Zhao XT. Drug-Drug Interactions of Newly Approved Direct-Acting Antiviral Agents in Patients with Hepatitis C. Int J Gen Med. 2021;14:289-301doi: 10.2147/IJGM.S283910.
Gao, L. H., Nie, Q. H., & Zhao, X. T. (2021). Drug-Drug Interactions of Newly Approved Direct-Acting Antiviral Agents in Patients with Hepatitis C. International journal of general medicine, 14289-301. https://doi.org/10.2147/IJGM.S283910
Gao, Lu-Hua, et al. "Drug-Drug Interactions of Newly Approved Direct-Acting Antiviral Agents in Patients with Hepatitis C." International journal of general medicine vol. 14 (2021): 289-301. doi: https://doi.org/10.2147/IJGM.S283910
Gao LH, Nie QH, Zhao XT. Drug-Drug Interactions of Newly Approved Direct-Acting Antiviral Agents in Patients with Hepatitis C. Int J Gen Med. 2021 Jan 28;14:289-301. doi: 10.2147/IJGM.S283910. eCollection 2021. PMID: 33536776; PMCID: PMC7850569.
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Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Li HL, Wang CP, Zhang Y, Du JX, Han LH, Yang HY.
PMID: 34859371
Clin Transl Oncol. 2021 Dec 03; doi: 10.1007/s12094-021-02736-0. Epub 2021 Dec 03.

PURPOSE: Breast cancer (BC) is one of the most common malignant tumors for women. The role and potential mechanisms of long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) were explored in BC cell migration and invasion.METHODS: PVT1, miR-148a-3p...

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Li HL, Wang CP, Zhang Y, et al. Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer. Clin Transl Oncol. 2021;doi: 10.1007/s12094-021-02736-0.
Li, H. L., Wang, C. P., Zhang, Y., Du, J. X., Han, L. H., & Yang, H. Y. (2021). Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, . https://doi.org/10.1007/s12094-021-02736-0
Li, H L, et al. "Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer." Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico vol. (2021). doi: https://doi.org/10.1007/s12094-021-02736-0
Li HL, Wang CP, Zhang Y, Du JX, Han LH, Yang HY. Long non-coding RNA PVT1 facilitates cell migration and invasion by regulating miR-148a-3p and ROCK1 in breast cancer. Clin Transl Oncol. 2021 Dec 03; doi: 10.1007/s12094-021-02736-0. Epub 2021 Dec 03. PMID: 34859371.
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Showing 601 to 612 of 623 entries