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Showing 25 to 36 of 265 entries
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Clinical and pathological factors predictive of response to neoadjuvant chemotherapy in breast cancer: A single center experience.

Oncology letters

Del Prete S, Caraglia M, Luce A, Montella L, Galizia G, Sperlongano P, Cennamo G, Lieto E, Capasso E, Fiorentino O, Aliberti M, Auricchio A, Iodice P, Addeo R.
PMID: 31516598
Oncol Lett. 2019 Oct;18(4):3873-3879. doi: 10.3892/ol.2019.10729. Epub 2019 Aug 07.

Neoadjuvant chemotherapy (NAC) of breast cancer (BC) improves outcomes, especially in patients with locally advanced and inflammatory cancer. Further insight into clinic-pathological factors influencing outcomes is essential to define the optimal therapeutic strategy for each category of patients and...

Infrared Spectroscopy of Polybenzimidazole in the Dry and Hydrate Forms: A Combined Experimental and Computational Study.

ACS omega

Musto P, La Manna P, Moon JD, Galizia M, Freeman BD.
PMID: 31459258
ACS Omega. 2018 Sep 21;3(9):11592-11607. doi: 10.1021/acsomega.8b01699. eCollection 2018 Sep 30.

In the present article, the infrared spectrum of polybenzimidazole (PBI) in the dry and hydrate forms has been studied both experimentally and theoretically to improve the interpretation of its complex features, especially in the ν(NH)/ν(OH) range, which is extensively...

What is the best pharmacotherapeutic strategy for HER-2 positive breast cancer?.

Expert opinion on pharmacotherapy

Giannone G, Milani A, Geuna E, Galizia D, Biello F, Montemurro F.
PMID: 30396301
Expert Opin Pharmacother. 2019 Jan;20(1):5-9. doi: 10.1080/14656566.2018.1543406. Epub 2018 Nov 06.

No abstract available.

Transition-metal-free one-pot synthesis of alkynyl selenides from terminal alkynes under aerobic and sustainable conditions.

Beilstein journal of organic chemistry

Heredia AA, Peñéñory AB.
PMID: 28684972
Beilstein J Org Chem. 2017 May 16;13:910-918. doi: 10.3762/bjoc.13.92. eCollection 2017.

Alkynyl selenides were synthesized by a straightforward one-pot and three-step methodology, without the need of diselenides as starting reagents, under an oxygen atmosphere and using PEG 200 as the solvent. This procedure involves the in situ generation of dialkyl...

Differential effect of flavonoids on glycosaminoglycan content and distribution in skin fibroblasts of patients with type I osteogenesis imperfecta.

Molecular medicine reports

Galicka A, Nazaruk J, Bruczko M.
PMID: 21472276
Mol Med Rep. 2010 May-Jun;3(3):537-41. doi: 10.3892/mmr_00000294.

We recently reported that, in osteogenesis imperfecta (OI) type I with diminished type I collagen biosynthesis, flavonoids such as apigenin 7-O-glucuronide, apigenin 7-O-methylglucuronide and pectolinarin normalized the level of collagen type I without affecting total protein synthesis. In addition...

Heavy Drinking in College Students Is Associated with Accelerated Gray Matter Volumetric Decline over a 2 Year Period.

Frontiers in behavioral neuroscience

Meda SA, Dager AD, Hawkins KA, Tennen H, Raskin S, Wood RM, Austad CS, Fallahi CR, Pearlson GD.
PMID: 29033801
Front Behav Neurosci. 2017 Sep 29;11:176. doi: 10.3389/fnbeh.2017.00176. eCollection 2017.

No abstract available.

Regioselective Photocycloaddition of Saccharin Anion to π-Systems: Continuous-Flow Synthesis of Benzosultams.

The Journal of organic chemistry

Figueroa FN, Heredia AA, Peñéñory AB, Sampedro D, Argüello JE, Oksdath-Mansilla G.
PMID: 30827103
J Org Chem. 2019 Apr 05;84(7):3871-3880. doi: 10.1021/acs.joc.8b02984. Epub 2019 Mar 13.

Saccharin is a versatile scaffold to build up different heterocycles with relevance in asymmetric catalysis, agricultural chemistry, medicinal chemistry, and so forth. Here, we report a photochemical strategy to obtain seven-membered ring benzosultams in one step, using saccharin anion...

Variation among populations in the immune protein composition of mother's milk reflects subsistence pattern.

Evolution, medicine, and public health

Klein LD, Huang J, Quinn EA, Martin MA, Breakey AA, Gurven M, Kaplan H, Valeggia C, Jasienska G, Scelza B, Lebrilla CB, Hinde K.
PMID: 30430010
Evol Med Public Health. 2018 Oct 13;2018(1):230-245. doi: 10.1093/emph/eoy031. eCollection 2018.

LAY SUMMARY: Adaptive immune proteins in mothers' milk are more variable than innate immune proteins across populations and subsistence strategies. These results suggest that the immune defenses in milk are shaped by a mother's environment throughout her life.BACKGROUND AND...

Imaging and modification of the tumor vascular barrier for improvement in magnetic nanoparticle uptake and hyperthermia treatment efficacy.

Proceedings of SPIE--the International Society for Optical Engineering

Hoopes PJ, Petryk AA, Tate JA, Savellano MS, Strawbridge RR, Giustini AJ, Stan RV, Gimi B, Garwood M.
PMID: 25285190
Proc SPIE Int Soc Opt Eng. 2013 Feb 26;8584. doi: 10.1117/12.2008689.

The predicted success of nanoparticle based cancer therapy is due in part to the presence of the inherent leakiness of the tumor vascular barrier, the so called enhanced permeability and retention (EPR) effect. Although the EPR effect is present...

Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.

Alzheimer's & dementia (New York, N. Y.)

Severino M, Sivasaravanaparan M, Olesen LØ, von Linstow CU, Metaxas A, Bouzinova EV, Khan AM, Lambertsen KL, Babcock AA, Gramsbergen JB, Wiborg O, Finsen B.
PMID: 29955664
Alzheimers Dement (N Y). 2018 May 24;4:215-223. doi: 10.1016/j.trci.2018.04.005. eCollection 2018.

INTRODUCTION: Treatment with selective serotonin reuptake inhibitors has been suggested to mitigate amyloid-β (Aβ) pathology in Alzheimer's disease, in addition to an antidepressant mechanism of action.METHODS: We investigated whether chronic treatment with paroxetine, a selective serotonin reuptake inhibitor, mitigates...

'Green', rammed earth check dams: A proposal to restore gullies under low rainfall erosivity and runoff conditions.

The Science of the total environment

Galicia S, Navarro-Hevia J, Martínez-Rodríguez A, Mongil-Manso J, Santibáñez J.
PMID: 31051365
Sci Total Environ. 2019 Aug 01;676:584-594. doi: 10.1016/j.scitotenv.2019.04.189. Epub 2019 Apr 17.

Gully restoration check dams are usually made with construction materials and have a permanent impact on the landscape. Although earthen dams have not been used to restore gullies, they have been used around the world for water reservoirs and...

Where Do Our Graduates Go? A Tool Kit for Tracking Career Outcomes of Biomedical PhD Students and Postdoctoral Scholars.

CBE life sciences education

Silva EA, Mejía AB, Watkins ES.
PMID: 31702952
CBE Life Sci Educ. 2019 Dec;18(4):le3. doi: 10.1187/cbe.19-08-0150.

No abstract available.

Showing 25 to 36 of 265 entries