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Showing 2233 to 2241 of 2241 entries
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Case Report: A case of encephalopathy presenting the lentiform fork sign on MRI in a diabetic dialysis patient - diabetic uremic syndrome or metformin-related encephalopathy?.

F1000Research

Ishizaki Y, Nishizono R, Kikuchi M, Inagaki H, Sato Y, Fujimoto S.
PMID: 34868569
F1000Res. 2020 Aug 11;9:969. doi: 10.12688/f1000research.25597.1. eCollection 2020.

Basal ganglia lesions showing an expansile high signal intensity on T2-weighted MRI are termed the lentiform fork sign. This specific finding is mainly observed in diabetic patients with uremic encephalopathy with metabolic acidosis, although there are also reports in...

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

NPJ breast cancer

El Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Yang W, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S.
PMID: 34853355
NPJ Breast Cancer. 2021 Dec 01;7(1):150. doi: 10.1038/s41523-021-00346-1.

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed death-ligand 1 (PD-L1). These patients...

Age-dependent effects on radiation-induced carcinogenesis in the rat thyroid.

Scientific reports

Matsuu-Matsuyama M, Shichijo K, Matsuda K, Fujimoto N, Kondo H, Miura S, Kurashige T, Nagayama Y, Nakashima M.
PMID: 34580369
Sci Rep. 2021 Sep 27;11(1):19096. doi: 10.1038/s41598-021-98481-z.

Childhood radiation exposure is a known thyroid cancer risk factor. This study evaluated the effects of age on radiation-induced thyroid carcinogenesis in rats irradiated with 8 Gy X-rays. We analyzed cell proliferation, cell death, DNA damage response, and autophagy-related...

Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.

Journal of autoimmunity

Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
PMID: 34896887
J Autoimmun. 2021 Dec 09;126:102774. doi: 10.1016/j.jaut.2021.102774. Epub 2021 Dec 09.

Intracellular proteins are often targeted by autoantibodies in autoimmune diseases; however, the mechanism through which intracellular molecules are targeted remains unknown. We previously found that several intracellular misfolded proteins are transported to the cell surface by HLA class II...

Gene therapy with SOCS1 induces potent preclinical antitumor activities in oral squamous cell carcinoma.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

Nakatani K, Serada S, Fujimoto M, Obata K, Ohkawara T, Sasabe E, Yamamoto T, Naka T.
PMID: 34878693
J Oral Pathol Med. 2021 Dec 08; doi: 10.1111/jop.13268. Epub 2021 Dec 08.

BACKGROUND: Constitutive activation of STAT3 promotes oncogenesis and growth of oral squamous cell carcinoma (OSCC). We investigated the mechanism of action of suppressor of cytokine signaling-1 (SOCS1), an endogenous inhibitor of JAK, as gene therapy for OSCC.METHODS: Antitumor effect...

Visualization of hypermetabolism in the ventral visual pathway by FDG-PET in the Charles Bonnet syndrome.

Clinical neurology and neurosurgery

Sasaki H, Fujimoto Y, Ima H, Kageyama Y.
PMID: 34329811
Clin Neurol Neurosurg. 2021 Sep;208:106832. doi: 10.1016/j.clineuro.2021.106832. Epub 2021 Jul 21.

A 74-year-old man presented with complex visual hallucinations with a left inferior quadrantanopia. The characteristics of the visual hallucinations met the criteria for the Charles Bonnet syndrome. Brain magnetic resonance imaging (MRI) revealed a right occipital falx meningioma. Fusion...

Faggot cells in acute myeloid leukemia with t(7;11)(p15;p15) and NUP98-HOXA9 fusion.

Annals of hematology

Yanagisawa H, Mizuta S, Kawabata H, Fujimoto S, Sakai T, Iwao-Kawanami H, Kawanami T, Yamada K, Fukushima T, Kyoda K, Masaki Y.
PMID: 32514625
Ann Hematol. 2021 Aug;100(8):2121-2123. doi: 10.1007/s00277-020-04122-2. Epub 2020 Jun 08.

No abstract available.

Prevalence and predictors of direct discharge home following hospitalization of patients with serious adverse events managed by the rapid response system in Japan: a multicenter, retrospective, observational study.

Acute medicine & surgery

Hongo T, Naito H, Fujiwara T, Naito T, Homma Y, Fujimoto Y, Takaya M, Yamamori Y, Nakada TA, Nojima T, Nakao A, Fujitani S.
PMID: 34430036
Acute Med Surg. 2021 Aug 16;8(1):e690. doi: 10.1002/ams2.690. eCollection 2021.

AIM: The rapid response system (RRS) is an in-hospital medical safety system. To date, not much is known about patient disposition after RRS activation, especially discharge home. This study aimed to investigate the prevalence, characteristics, and outcomes of patients...

Basal cell carcinoma on the ventral site of the finger with an intronic deletion of SUFU gene.

Journal of the European Academy of Dermatology and Venereology : JEADV

Takata M, Komori T, Ishida Y, Fujimoto M, Ogawa S, Kabashima K.
PMID: 34553799
J Eur Acad Dermatol Venereol. 2022 Feb;36(2):e128-e130. doi: 10.1111/jdv.17694. Epub 2021 Sep 30.

No abstract available.

Showing 2233 to 2241 of 2241 entries