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Showing 4021 to 4030 of 4030 entries
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Preparation of Oxysterols by C-H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst.

Molecules (Basel, Switzerland)

Fujii Y, Yoritate M, Makino K, Igawa K, Takeda D, Doiuchi D, Tomooka K, Uchida T, Hirai G.
PMID: 35011456
Molecules. 2021 Dec 30;27(1). doi: 10.3390/molecules27010225.

Seven mono- and dihydroxycholesterols were prepared by direct C-H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh

Targeted amplicon sequencing for primary tumors and matched lymph node metastases in patients with extrahepatic cholangiocarcinoma.

HPB : the official journal of the International Hepato Pancreato Biliary Association

Yamada T, Nakanishi Y, Hayashi H, Tanishima S, Mori R, Fujii K, Okamura K, Tsuchikawa T, Nakamura T, Noji T, Asano T, Matsui A, Tanaka K, Watanabe Y, Kurashima Y, Ebihara Y, Murakami S, Shichinohe T, Mitsuhashi T, Hirano S.
PMID: 34903468
HPB (Oxford). 2021 Nov 25; doi: 10.1016/j.hpb.2021.11.008. Epub 2021 Nov 25.

BACKGROUND: Lymph node metastasis (LNM) is one of the most adverse prognostic factors in extrahepatic cholangiocarcinoma (EHCC) cases. As next-generation sequencing technology has become more widely available, the genomic profile of biliary tract carcinoma has been clarified. However, whether...

Enrichment of plasmid pool from .

STAR protocols

Isogawa A, Fuchs RP, Fujii S.
PMID: 33786464
STAR Protoc. 2021 Mar 20;2(2):100399. doi: 10.1016/j.xpro.2021.100399. eCollection 2021 Jun 18.

Translesion synthesis (TLS) is an event to cope with DNA damages. During TLS, the responsible TLS polymerase frequently elicits untargeted mutagenesis as potentially a source of genetic diversity. Identifying such untargeted mutations

Albuminuria predicts worsening renal function after transcatheter aortic valve replacement.

Journal of cardiology

Tobe A, Tanaka A, Tokuda Y, Fujii T, Furusawa K, Ishii H, Usui A, Murohara T.
PMID: 34903422
J Cardiol. 2021 Dec 10; doi: 10.1016/j.jjcc.2021.11.014. Epub 2021 Dec 10.

BACKGROUND: The impact of albuminuria on worsening renal function (WRF) and clinical outcomes after transcatheter aortic valve replacement (TAVR) is unknown.METHODS: Overall, 142 patients who underwent TAVR for severe aortic stenosis were divided into two groups based on the...

Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer.

Journal of oncology

Baba Y, Fujii M, Tokumaru Y, Kato Y.
PMID: 22545054
J Oncol. 2012;2012:986725. doi: 10.1155/2012/986725. Epub 2012 Mar 26.

Although EGFR is expressed at high levels in head and neck squamous cell carcinomas (HNSCCs) and mutations are extremely rare, monotherapy with EGFR inhibitors has shown limited success. The PI3kinase/Akt pathway is responsible for cellular survival, and inhibition of...

Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting.

Human pathology

Lam AK, Bourke MJ, Chen R, Fiocca R, Fujishima F, Fujii S, Jansen M, Kumarasinghe P, Langer R, Law S, Meijer SL, Muldoon C, Novelli M, Shi C, Tang L, Nagtegaal ID.
PMID: 33992659
Hum Pathol. 2021 Aug;114:54-65. doi: 10.1016/j.humpath.2021.05.003. Epub 2021 May 13.

BACKGROUND AND OBJECTIVES: A standardized data set for esophageal carcinoma pathology reporting was developed based on the approach of the International Collaboration on Cancer Reporting (ICCR) for the purpose of improving cancer patient outcomes and international benchmarking in cancer...

Analysis of Repeated Measurements of Serum Carotenoid Levels and All-Cause and Cause-Specific Mortality in Japan.

JAMA network open

Fujii R, Tsuboi Y, Maeda K, Ishihara Y, Suzuki K.
PMID: 34115126
JAMA Netw Open. 2021 Jun 01;4(6):e2113369. doi: 10.1001/jamanetworkopen.2021.13369.

IMPORTANCE: The associations of levels of diverse serum carotenoids ascertained via repeated measurements with all-cause, cancer, and cardiovascular disease (CVD) mortality risk have not been considered in previous prospective studies.OBJECTIVE: To investigate the association between repeated measurement of serum...

Clinical study of modulated electro-hyperthermia for advanced metastatic breast cancer.

Molecular and clinical oncology

Nagata T, Kanamori M, Sekine S, Arai M, Moriyama M, Fujii T.
PMID: 33796292
Mol Clin Oncol. 2021 May;14(5):103. doi: 10.3892/mco.2021.2265. Epub 2021 Mar 17.

Modulated electro-hyperthermia (mEHT) is a new treatment modality developed to overcome the problems associated with traditional hyperthermia; mEHT uses a precise impedance-matched system and modulated radiofrequency current flow to malignant tumors. It selects the malignant cells based on their...

Risk Factors for Failure of Endoscopic Management of Stone-related Ureteral Strictures.

Urology journal

Sugino T, Taguchi K, Hamamoto S, Okada T, Isogai M, Tanaka Y, Unno R, Fujii Y, Hamakawa T, Ando R, Okada A, Yasui T.
PMID: 34431077
Urol J. 2021 Aug 25;6697. doi: 10.22037/uj.v18i.6697. Epub 2021 Aug 25.

PURPOSE: To investigate factors determining the outcomes of endoscopic management for stone-related ureteral stricture.MATERIALS AND METHODS: Data of patients who underwent endoscopic surgery for ureteral stricture due to stones from January 2016 to April 2020 were retrospectively analyzed. We...

Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner.

The Journal of nutritional biochemistry

Tanaka E, Mitani T, Nakashima M, Yonemoto E, Fujii H, Ashida H.
PMID: 34748921
J Nutr Biochem. 2022 Feb;100:108898. doi: 10.1016/j.jnutbio.2021.108898. Epub 2021 Nov 05.

The adipocytes play an important role in driving the obese-state-white adipose tissue (WAT) stores the excess energy as fat, wherein brown adipose tissue (BAT) is responsible for energy expenditure via the thermoregulatory function of uncoupling protein 1 (UCP1)-the imbalance...

Showing 4021 to 4030 of 4030 entries