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Showing 13 to 24 of 625 entries
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Genetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary Syndrome.

Frontiers in endocrinology

Huang-Doran I, Franks S.
PMID: 27375552
Front Endocrinol (Lausanne). 2016 Jun 07;7:53. doi: 10.3389/fendo.2016.00053. eCollection 2016.

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women and a leading cause of female infertility worldwide. Defined clinically by the presence of hyperandrogenemia and oligomenorrhoea, PCOS represents a state of hormonal dysregulation, disrupted ovarian follicle dynamics,...

Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.

Nature communications

Hayes MG, Urbanek M, Ehrmann DA, Armstrong LL, Lee JY, Sisk R, Karaderi T, Barber TM, McCarthy MI, Franks S, Lindgren CM, Welt CK, Diamanti-Kandarakis E, Panidis D, Goodarzi MO, Azziz R, Zhang Y, James RG, Olivier M, Kissebah AH, Stener-Victorin E, Legro RS, Dunaif A.
PMID: 26867975
Nat Commun. 2016 Feb 12;7:10762. doi: 10.1038/ncomms10762.

No abstract available.

The surface variational principle applied to an acoustic cavity.

The Journal of the Acoustical Society of America

Franco F, Cunefare KA.
PMID: 11425122
J Acoust Soc Am. 2001 Jun;109(6):2797-804. doi: 10.1121/1.1369107.

This paper presents the development and application of the Surface Variational Principle (SVP) for the evaluation of axisymmetric interior acoustic domains. The interior form of the SVP is first developed in the same manner as the existing exterior form....

Chemical and mass spectrometric sequence studies of a peptide from the variable part of normal immunoglobulin lambda-chains.

FEBS letters

Franek F, Keil B, Thomas DW, Lederer E.
PMID: 11946341
FEBS Lett. 1969 Mar;2(5):309-312. doi: 10.1016/0014-5793(69)80050-5.

No abstract available.

Development of soluble glasses for biomedical use Part I: in vitro solubility measurement.

Journal of materials science. Materials in medicine

Franks K, Abrahams I, Knowles JC.
PMID: 15348084
J Mater Sci Mater Med. 2000 Oct;11(10):609-14. doi: 10.1023/a:1008949527695.

In this study soluble glasses have been developed for biomedical applications containing P2O5 as a network former and CaO and Na2O as modifiers. This study shows that as expected, the glasses have an inverse exponential relationship between solubility and...

Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor gamma with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development.

PPAR research

Mansour MM, Goyal HO, Braden TD, Dennis JC, Schwartz DD, Judd RL, Bartol FF, Coleman ES, Morrison EE.
PMID: 18769493
PPAR Res. 2008;2008:651419. doi: 10.1155/2008/651419.

Exposure to the estrogen receptor alpha (ERalpha) ligand diethylstilbesterol (DES) between neonatal days 2 to 12 induces penile adipogenesis and adult infertility in rats. The objective of this study was to investigate the in vivo interaction between DES-activated ERalpha...

Chemically synthesized zinc finger molecules as nano-addressable probes for double-stranded DNAs.

Journal of nanobiotechnology

von Nickisch-Rosenegk M, Ehrentreich-Forster E, Strehlow R, Christmann A, Bier FF.
PMID: 15985184
J Nanobiotechnology. 2005 Jun 29;3:5. doi: 10.1186/1477-3155-3-5.

Our experiments describe an alternative method of dsDNA recognition using zinc finger (ZF) molecules which bind DNA specifically and with high affinity. Our aim was to develop zinc finger probes which are able to bind to dsDNA molecules at...

Localization of NADPH-protochlorophyllide reductase in plastids of barley at different greening stages.

Photosynthesis research

Barthélemy X, Bouvier G, Radunz A, Docquier S, Schmid GH, Franck F.
PMID: 16228444
Photosynth Res. 2000;64(1):63-76. doi: 10.1023/A:1026576319029.

The localization of protochorophyllide (Pchlide) and of NADPH-protochlorophyllide oxidoreductase (POR, EC 1.6.99.1) within (etio)chloroplasts has been investigated at selected stages of greening of barley seedlings. Pchlide pigment and POR protein contents were evaluated in different plastid membrane fractions by...

Work site, physician's office, or medical university clinic: the effect of setting on success in a multidisciplinary weight-loss program.

Eating behaviors

Hoke CN, Franks S.
PMID: 15001023
Eat Behav. 2002;3(1):93-100. doi: 10.1016/s1471-0153(01)00053-8.

The effect of treatment setting on success in a 16-week multidisciplinary cognitive-behavioral weight-management program was examined. Twenty-seven women and six men with an average initial weight of 198.13 lb (+/-39.10) participated in the program at a medical university (MU),...

Primary sclerosing cholangitis: High-dose ursodeoxycholic acid is associated with risk of colonic neoplasia in patients with PSC and ulcerative colitis.

Nature reviews. Gastroenterology & hepatology

Franks I.
PMID: 21725347
Nat Rev Gastroenterol Hepatol. 2011 Jul 04;8(7):361. doi: 10.1038/nrgastro.2011.99.

No abstract available.

Current developments in the molecular genetics of the polycystic ovary syndrome.

Trends in endocrinology and metabolism: TEM

Franks S, Gharani N, Waterworth D, Batty S, White D, Williamson R, McCarthy M.
PMID: 18406240
Trends Endocrinol Metab. 1998 Feb;9(2):51-4. doi: 10.1016/s1043-2760(98)00018-6.

Polycystic ovary syndrome (PCOS) is most likely a complex trait with an oligogenic basis. In this article, we present evidence from molecular genetic studies for involvement of the steroid synthesis gene CYP11a (coding for P450 cholesterol side-chain cleavage) in...

Treatment of chronic obstructive pulmonary disease and its comorbidities.

Proceedings of the American Thoracic Society

Luppi F, Franco F, Beghé B, Fabbri LM.
PMID: 19017740
Proc Am Thorac Soc. 2008 Dec 01;5(8):848-56. doi: 10.1513/pats.200809-101TH.

While chronic obstructive pulmonary disease (COPD) is still characterized and diagnosed by lung function measurements, there is increasing evidence that the chronic diseases that frequently develop with COPD in response to the common risk factors (smoking, aging, obesity) may...

Showing 13 to 24 of 625 entries