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Kinship Reconsidered: Research on a Neglected Topic.

Journal of marriage and the family

Furstenberg FF.
PMID: 34334811
J Marriage Fam. 2020 Feb;82(1):364-382. doi: 10.1111/jomf.12628. Epub 2020 Jan 05.

No abstract available.

Intraurethral Energy Harvesting from Urine Flow as an Approach to Power Urologic Implants.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Benke E, Stoinski RT, Preis A, Reitelshofer S, Martin S, Franke J.
PMID: 34892764
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:7215-7218. doi: 10.1109/EMBC46164.2021.9630116.

Active urologic implants, such as bladder stimulators or artificial sphincters, are a widely-used approach for therapy of urinary incontinence. At present these devices are powered by primary batteries or conventional wireless power transferring techniques. As these methods are associated...

Cell-type specialization is encoded by specific chromatin topologies.

Nature

Winick-Ng W, Kukalev A, Harabula I, Zea-Redondo L, Szabó D, Meijer M, Serebreni L, Zhang Y, Bianco S, Chiariello AM, Irastorza-Azcarate I, Thieme CJ, Sparks TM, Carvalho S, Fiorillo L, Musella F, Irani E, Triglia ET, Kolodziejczyk AA, Abentung A, Apostolova G, Paul EJ, Franke V, Kempfer R, Akalin A, Teichmann SA, Dechant G, Ungless MA, Nicodemi M, Welch L, Castelo-Branco G, Pombo A.
PMID: 34789882
Nature. 2021 Nov;599(7886):684-691. doi: 10.1038/s41586-021-04081-2. Epub 2021 Nov 17.

The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function

Influence of reduction quality on functional outcome and quality of life in the surgical treatment of tibial plateau fractures: A retrospective cohort study.

Orthopaedics & traumatology, surgery & research : OTSR

Beisemann N, Vetter SY, Keil H, Swartman B, Schnetzke M, Franke J, Grützner PA, Privalov M.
PMID: 33836282
Orthop Traumatol Surg Res. 2021 Apr 06;102922. doi: 10.1016/j.otsr.2021.102922. Epub 2021 Apr 06.

BACKGROUND: Despite a substantial improvement in the operative treatment of tibial plateau fractures, the surgical procedure remains controversial and is generally challenging, as patients may develop postoperative arthritis and functional impairment of the knee joint.HYPOTHESIS: In the surgical treatment...

High-throughput identification of conditional MHCI ligands and scaled-up production of conditional MHCI complexes.

Protein science : a publication of the Protein Society

Darwish M, Wichner S, Li J, Chang JC, Tam C, Franke Y, Li H, Chan P, Blanchette C.
PMID: 33840137
Protein Sci. 2021 Jun;30(6):1169-1183. doi: 10.1002/pro.4082. Epub 2021 Apr 26.

Despite the need to monitor the impact of Cancer Immunotherapy (CI)/Immuno-Oncology (IO) therapeutics on neoantigen-specific T-cell responses, very few clinical programs incorporate this aspect of immune monitoring due to the challenges in high-throughput (HTP) generation of Major Histocompatibility Complex...

Senior Entrepreneurship: The Unrevealed Driver for Social Innovation.

Frontiers in sociology

Stypińska J, Franke A, Myrczik J.
PMID: 33869354
Front Sociol. 2019 Apr 24;4:30. doi: 10.3389/fsoc.2019.00030. eCollection 2019.

From a political and economic perspective, senior entrepreneurship seems to be the response to the demographic consequences of the aging workforce in Europe. Several policies and strategies by the European Union (EU) and the Organization for Economic Co-operation and...

Genomic Profiling of Premenopausal HR+ and HER2- Metastatic Breast Cancer by Circulating Tumor DNA and Association of Genetic Alterations With Therapeutic Response to Endocrine Therapy and Ribociclib.

JCO precision oncology

Bardia A, Su F, Solovieff N, Im SA, Sohn J, Lee KS, Campos-Gomez S, Jung KH, Colleoni M, Vázquez RV, Franke F, Hurvitz S, Harbeck N, Chow L, Taran T, Rodriguez Lorenc K, Babbar N, Tripathy D, Lu YS.
PMID: 34504990
JCO Precis Oncol. 2021 Sep 01;5. doi: 10.1200/PO.20.00445. eCollection 2021.

PURPOSE: This analysis evaluated the genomic landscape of premenopausal patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative advanced breast cancer and the association of genetic alterations with response to ribociclib in the phase III MONALEESA-7 trial.METHODS:...

Ten years of enhancing neuro-imaging genetics through meta-analysis: An overview from the ENIGMA Genetics Working Group.

Human brain mapping

Medland SE, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Thomopoulos SI, Stein JL, Franke B, Martin NG, Thompson PM.
PMID: 33300665
Hum Brain Mapp. 2020 Dec 10; doi: 10.1002/hbm.25311. Epub 2020 Dec 10.

Here we review the motivation for creating the enhancing neuroimaging genetics through meta-analysis (ENIGMA) Consortium and the genetic analyses undertaken by the consortium so far. We discuss the methodological challenges, findings, and future directions of the genetics working group....

G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment.

Journal for immunotherapy of cancer

Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K.
PMID: 34049929
J Immunother Cancer. 2021 May;9(5). doi: 10.1136/jitc-2020-002259.

BACKGROUND: Current immunotherapy for patients with high-risk neuroblastoma involves the therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority of neuroblastoma tumors. Opsonized tumor cells are killed through antibody-dependent cellular cytotoxicity (ADCC), a process mediated by...

Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution.

Lab on a chip

Link A, McGrath JS, Zaimagaoglu M, Franke T.
PMID: 34889927
Lab Chip. 2021 Dec 21;22(1):193-200. doi: 10.1039/d1lc00880c.

We demonstrate the use of an acoustic device to actively encapsulate single red blood cells into individual droplets in a T-junction. We compare the active encapsulation with the passive encapsulation depending on the number of loaded cells as well...

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling.

Stem cells translational medicine

Manstein F, Ullmann K, Kropp C, Halloin C, Triebert W, Franke A, Farr CM, Sahabian A, Haase A, Breitkreuz Y, Peitz M, Brüstle O, Kalies S, Martin U, Olmer R, Zweigerdt R.
PMID: 33660952
Stem Cells Transl Med. 2021 Jul;10(7):1063-1080. doi: 10.1002/sctm.20-0453. Epub 2021 Mar 04.

To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC-specific hurdles toward their mass production. Perfused suspension culture...

Phantom epistasis between unlinked loci.

Nature

Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, Visscher PM.
PMID: 34381229
Nature. 2021 Aug;596(7871):E1-E3. doi: 10.1038/s41586-021-03765-z. Epub 2021 Aug 11.

No abstract available.

Showing 1069 to 1080 of 1080 entries