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Bis(1,10-phenanthroline)(thiosulfato)manganese(II) methanol solvate and catena-poly[[diaqua(2,9-dimethyl-1,10-phenanthroline)manganese(II)]-mu-thiosulfato].

Acta crystallographica. Section C, Crystal structure communications

Freire E, Baggio S, Muñoz JC, Baggio R.
PMID: 12154293
Acta Crystallogr C. 2002 Aug;58:m455-8. doi: 10.1107/s0108270102012404. Epub 2002 Jul 31.

The structure of bis(1,10-phenanthroline-kappa(2)N,N')(thiosulfato-kappa(2)O:S)manganese(II) methanol solvate, [Mn(S(2)O(3))(C(12)H(8)N(2))(2)].CH(3)OH, is made up of Mn(2+) centers coordinated to two bidentate phenanthroline (phen) groups and an S,O-chelating thiosulfate anion, forming monomeric entities. The structure of catena-poly[[diaqua(2,9-dimethyl-1,10-phenanthroline-kappa(2)N,N')manganese(II)]-mu-thiosulfato-kappa(2)O:S], [Mn(S(2)O(3))(C(14)H(12)N(2))(H(2)O)(2)](n), is polymeric, consisting of Mn(dmph)(H(2)O)(2) units...

Ecological fitting is the forerunner to diversification in a plant virus with broad host range.

Journal of evolutionary biology

Peláez A, McLeish MJ, Paswan RR, Dubay B, Fraile A, García-Arenal F.
PMID: 32618008
J Evol Biol. 2020 Jul 02; doi: 10.1111/jeb.13672. Epub 2020 Jul 02.

The evolution and diversification of ssRNA plant viruses are often examined under reductionist conditions that ignore potentially much wider biotic interactions. The host range of a plant virus is central to interactions at higher levels that are organized by...

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Nature medicine

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA.
PMID: 30552419
Nat Med. 2019 Jan;25(1):188-189. doi: 10.1038/s41591-018-0315-0.

In the version of this article originally published, data were incorrectly ascribed to monoclonal antibody CIS34 because of a labeling error. The data were generated with monoclonal antibody CIS04. Full details can be found in the correction notice.

PeerJ

Giraldes BW, Macedo TP, Brandão MC, Baeza JA, Freire AS.
PMID: 30202657
PeerJ. 2018 Sep 05;6:e5561. doi: 10.7717/peerj.5561. eCollection 2018.

No abstract available.

Pleiotropic Effects of Resistance-Breaking Mutations on Particle Stability Provide Insight into Life History Evolution of a Plant RNA Virus.

Journal of virology

Bera S, Moreno-Pérez MG, García-Figuera S, Pagán I, Fraile A, Pacios LF, García-Arenal F.
PMID: 28679755
J Virol. 2017 Aug 24;91(18). doi: 10.1128/JVI.00435-17. Print 2017 Sep 15.

In gene-for-gene host-virus interactions, virus evolution to infect and multiply in previously resistant host genotypes, i.e., resistance breaking, is a case of host range expansion, which is predicted to be associated with fitness penalties. Negative effects of resistance-breaking mutations...

Intramolecular hydrogen-bond activation for the addition of nucleophilic imines: 2-hydroxybenzophenone as a chemical auxiliary.

Chemical communications (Cambridge, England)

Choubane H, Garrido-Castro AF, Alvarado C, Martín-Somer A, Guerrero-Corella A, Daaou M, Díaz-Tendero S, Carmen Maestro M, Fraile A, Alemán J.
PMID: 29557452
Chem Commun (Camb). 2018 Mar 29;54(27):3399-3402. doi: 10.1039/C8CC01479E.

The addition of nucleophilic imines, using 2-hydroxybenzophenone as a chemical auxiliary, is presented. An intramolecular six-membered ring via hydrogen bonding that enhances the reactivity and selectivity is the key of this strategy, which is supported by DFT calculations and...

Occurrence of Beet black scorch virus Infecting Sugar Beet in Europe.

Plant disease

González-Vázquez M, Ayala J, García-Arenal F, Fraile A.
PMID: 30764261
Plant Dis. 2009 Jan;93(1):21-24. doi: 10.1094/PDIS-93-1-0021.

In a survey of soilborne viruses infecting sugar beet in central Spain, Beet black scorch virus (BBSV) was detected in field grown sugar beets with symptoms of rhizomania disease. BBSV was found in all analyzed sugar beet producing regions...

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.

ACS medicinal chemistry letters

Lalonde JM, Le-Khac M, Jones DM, Courter JR, Park J, Schön A, Princiotto AM, Wu X, Mascola JR, Freire E, Sodroski J, Madani N, Hendrickson WA, Smith AB.
PMID: 23667716
ACS Med Chem Lett. 2013 Mar 14;4(3):338-343. doi: 10.1021/ml300407y.

The design, synthesis, thermodynamic and crystallographic characterization of a potent, broad spectrum, second-generation HIV-1 entry inhibitor that engages conserved carbonyl hydrogen bonds within gp120 has been achieved. The optimized antagonist exhibits a sub-micromolar binding affinity (110 nM) and inhibits...

Poly[[tetra-μ3-acetato-hexa-μ2-acetato-diaqua-μ2-oxalato-tetrapraseodymium(III)] dihydrate].

Acta crystallographica. Section C, Crystal structure communications

Gutkowski K, Freire E, Baggio R.
PMID: 21368405
Acta Crystallogr C. 2011 Mar;67:m77-80. doi: 10.1107/S0108270111005403. Epub 2011 Feb 18.

The title complex, {[Pr(4)(C(2)H(3)O(2))(10)(C(2)O(4))(H(2)O)(2)]·2H(2)O}(n), was synthesized under hydrothermal conditions from praseodymium acetate and the ionic liquid 1-butyl-3-methylimidazolium chloride via an in situ oxalate-ligand synthesis. The compound is a two-dimensional polymer and in the structure presents tightly bound planes parallel...

A model of genetic guidance for hemoglobinopathy patients and laboratory diagnosis of family members as educational and preventive measures.

Revista brasileira de hematologia e hemoterapia

Ferreira TD, Freire AS, Silveira-Lacerda Ede P, García-Zapata MT.
PMID: 23125541
Rev Bras Hematol Hemoter. 2012;34(5):339-44. doi: 10.5581/1516-8484.20120089.

BACKGROUND: The high frequency of hemoglobinopathies in Brazil constitutes a public health problem and thus educational and preventive measures are necessary to reduce the incidence. Genetic guidance, a modality of genetic counseling, and family screening are measures that can...

Complex magnetic behavior in the novel Kondo lattice compound CeRhSn₃.

Journal of physics. Condensed matter : an Institute of Physics journal

Anand VK, Adroja DT, Hillier AD, Kockelmann W, Fraile A, Strydom AM.
PMID: 21673393
J Phys Condens Matter. 2011 Jul 13;23(27):276001. doi: 10.1088/0953-8984/23/27/276001. Epub 2011 Jun 15.

We report the magnetic and transport properties of a new ternary intermetallic compound, CeRhSn₃, using magnetic susceptibility, magnetization, specific heat, electrical resistivity, muon-spin relaxation (μSR) and neutron diffraction investigations. The dc magnetic susceptibility data reveal two magnetic phase transitions...

A molecular method for the detection of sally lightfoot crab larvae (Grapsus grapsus, Brachyura, Grapsidae) in plankton samples.

Genetics and molecular biology

Ströher PR, Firkowski CR, Freire AS, Pie MR.
PMID: 21931530
Genet Mol Biol. 2011 Jul;34(3):529-31. doi: 10.1590/S1415-47572011005000020. Epub 2011 Jul 01.

The decapod Grapsus grapsus is commonly found on oceanic islands of the Pacific and Atlantic coasts of the Americas. In this study, a simple, quick and reliable method for detecting its larvae in plankton samples is described, which makes...

Showing 25 to 36 of 158 entries