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Showing 25 to 36 of 191 entries
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Transforming the Paradigm for Lipid Lowering.

JAMA cardiology

Navar AM, Fonarow GC.
PMID: 34550298
JAMA Cardiol. 2021 Dec 01;6(12):1414. doi: 10.1001/jamacardio.2021.3517.

No abstract available.

Frequency, Characteristics, and Outcomes of Endovascular Thrombectomy in Patients With Stroke Beyond 6 Hours of Onset in US Clinical Practice.

Stroke

Zachrison KS, Schwamm LH, Xu H, Matsouaka R, Shah S, Smith EE, Xian Y, Fonarow GC, Saver J.
PMID: 34470490
Stroke. 2021 Dec;52(12):3805-3814. doi: 10.1161/STROKEAHA.121.034069. Epub 2021 Sep 02.

BACKGROUND AND PURPOSE: In 2018, 2 randomized controlled trials showed the benefit of endovascular thrombectomy (EVT) in acute ischemic stroke patients treated 6 to 24 hours from last known well using imaging-guided selection. However, little is known about outcomes...

National Trends in Heart Failure Hospitalizations and Readmissions From 2010 to 2017.

JAMA cardiology

Agarwal MA, Fonarow GC, Ziaeian B.
PMID: 33566058
JAMA Cardiol. 2021 Aug 01;6(8):952-956. doi: 10.1001/jamacardio.2020.7472.

IMPORTANCE: Previous studies have described the secular trends of overall heart failure (HF) hospitalizations, but the literature describing the national trends of unique index hospitalizations and readmission visits for the primary management of HF is lacking.OBJECTIVES: To examine contemporary...

Sodium-glucose co-transporter 2 inhibitors as an early, first line therapy in patients with heart failure and reduced ejection fraction.

European journal of heart failure

Tomasoni D, Fonarow GC, Adamo M, Anker SD, Butler J, Coats AJ, Filippatos G, Greene SJ, McDonagh TA, Ponikowski P, Rosano G, Seferovic P, Vaduganathan M, Voors AA, Metra M.
PMID: 34894038
Eur J Heart Fail. 2021 Dec 10; doi: 10.1002/ejhf.2397. Epub 2021 Dec 10.

Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been recently recommended as a foundational therapy for patients with heart failure (HF) and reduced ejection fraction (HFrEF) because of their favourable effects on mortality, clinical events and quality of life. While clinical...

Is the Left Ventricular Ejection Fraction Measurement Still Preeminent?-New Measures to Quantify Subclinical Systolic Dysfunction.

JAMA cardiology

Yancy CW, Fonarow GC.
PMID: 33729426
JAMA Cardiol. 2021 May 01;6(5):521. doi: 10.1001/jamacardio.2021.0143.

No abstract available.

Trends in Utilization and Cost of Low-Density Lipoprotein Cholesterol-Lowering Therapies Among Medicare Beneficiaries: An Analysis From the Medicare Part D Database.

JAMA cardiology

Sumarsono A, Lalani HS, Vaduganathan M, Navar AM, Fonarow GC, Das SR, Pandey A.
PMID: 32902560
JAMA Cardiol. 2021 Jan 01;6(1):92-96. doi: 10.1001/jamacardio.2020.3723.

IMPORTANCE: Low-density lipoprotein cholesterol (LDL-C)-lowering therapies are a cornerstone of prevention in atherosclerotic cardiovascular disease. With the introduction of generic formulations and the release of new therapies, including proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, contemporary Medicare utilization of...

Association of Optimal Implementation of Sodium-Glucose Cotransporter 2 Inhibitor Therapy With Outcome for Patients With Heart Failure.

JAMA cardiology

Bassi NS, Ziaeian B, Yancy CW, Fonarow GC.
PMID: 32374344
JAMA Cardiol. 2020 Aug 01;5(8):948-951. doi: 10.1001/jamacardio.2020.0898.

IMPORTANCE: Sodium-glucose cotransporter 2 inhibitor (SGLT2-i) therapy provided incremental survival benefit to patients with heart failure and reduced ejection fraction (HFrEF) who received guideline-directed medical therapy regardless of type 2 diabetes status in a recent clinical trial. To date,...

Diuretic Changes, Health Care Resource Utilization, and Clinical Outcomes for Heart Failure With Reduced Ejection Fraction: From the Change the Management of Patients With Heart Failure Registry.

Circulation. Heart failure

Khan MS, Greene SJ, Hellkamp AS, DeVore AD, Shen X, Albert NM, Patterson JH, Spertus JA, Thomas LE, Williams FB, Hernandez AF, Fonarow GC, Butler J.
PMID: 34674536
Circ Heart Fail. 2021 Nov;14(11):e008351. doi: 10.1161/CIRCHEARTFAILURE.121.008351. Epub 2021 Oct 22.

BACKGROUND: Diuretics are a mainstay therapy for the symptomatic treatment of heart failure. However, in contemporary US outpatient practice, the degree to which diuretic dosing changes over time and the associations with clinical outcomes and health care resource utilization...

Outcomes of Endovascular Therapy in Patients With Prestroke Mobility Impairment.

Stroke

Beekman R, Sun JL, Alhanti B, Schwamm LH, Smith EE, Bhatt DL, Xian Y, Shah S, Lytle BL, Fonarow GC, Sheth KN.
PMID: 34517771
Stroke. 2021 Nov;52(11):e725-e728. doi: 10.1161/STROKEAHA.121.034464. Epub 2021 Sep 14.

BACKGROUND AND PURPOSE: Patients with prestroke mobility impairment (PSMI) were excluded from endovascular clinical trials. There are limited data regarding safety and outcomes of endovascular thrombectomy in this population. We used a large, national data set (Get With The...

Transforming the Paradigm for Lipid Lowering.

JAMA cardiology

Navar AM, Fonarow GC.
PMID: 34550298
JAMA Cardiol. 2021 Sep 22; doi: 10.1001/jamacardio.2021.3517. Epub 2021 Sep 22.

No abstract available.

Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD.

Stroke and vascular neurology

Shah S, Liang L, Bhandary D, Johansson S, Smith EE, Bhatt DL, Fonarow GC, Khan ND, Peterson E, Bettger JP.
PMID: 33148542
Stroke Vasc Neurol. 2021 Jun;6(2):314-318. doi: 10.1136/svn-2020-000372. Epub 2020 Nov 04.

BACKGROUND: Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack (TIA) and role of ABCDMETHODS: We identified 40 825 Medicare beneficiaries hospitalised from 2011 to 2014 for a TIA to a Get With The Guidelines (GWTG)-Stroke hospital and...

Cost-effectiveness of PCSK9 inhibition with evolocumab in patients with a history of myocardial infarction in Sweden.

European heart journal. Quality of care & clinical outcomes

Landmesser U, Lindgren P, Hagström E, van Hout B, Villa G, Pemberton-Ross P, Arellano J, Svensson ME, Sibartie M, Fonarow GC.
PMID: 33063111
Eur Heart J Qual Care Clin Outcomes. 2020 Oct 16; doi: 10.1093/ehjqcco/qcaa072. Epub 2020 Oct 16.

AIMS: To assess the cost-effectiveness of PCSK9 inhibition with evolocumab added to standard-of-care lipid-lowering treatment (maximum tolerated dose [MTD] of statin and ezetimibe) in Swedish patients with a history of myocardial infarction (MI).METHODS AND RESULTS: Cost-effectiveness was evaluated using...

Showing 25 to 36 of 191 entries