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Showing 181 to 191 of 191 entries
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Antithrombotic Therapy for Stroke Prevention in Patients With Ischemic Stroke With Aspirin Treatment Failure.

Stroke

Lusk JB, Xu H, Peterson ED, Bhatt DL, Fonarow GC, Smith EE, Matsouaka R, Schwamm LH, Xian Y.
PMID: 34702067
Stroke. 2021 Dec;52(12):e777-e781. doi: 10.1161/STROKEAHA.121.034622. Epub 2021 Oct 27.

BACKGROUND AND PURPOSE: Many older patients presenting with acute ischemic stroke were already taking aspirin before admission. However, the management strategy for patients with aspirin treatment failure has not been fully established.METHODS: We used data from the American Heart...

Non-Pharmaceutical Interventions and COVID-19 Burden in the United States.

medRxiv : the preprint server for health sciences

Ahlers MJ, Aralis HJ, Tang WL, Sussman JB, Fonarow GC, Ziaeian B.
PMID: 34611668
medRxiv. 2021 Sep 28; doi: 10.1101/2021.09.26.21264142.

BACKGROUND: Non-pharmaceutical interventions (NPIs) are mitigation strategies used to reduce the spread of transmissible diseases. The relative effectiveness of specific NPIs remains uncertain.METHODS: We used state-level Coronavirus disease 2019 (COVID-19) case and mortality data between January 19, 2020 and...

Is the affordable care act medicaid expansion associated with receipt of heart failure guideline-directed medical therapy by race and ethnicity?.

American heart journal

Breathett KK, Xu H, Sweitzer NK, Calhoun E, Matsouaka RA, Yancy CW, Fonarow GC, DeVore AD, Bhatt DL, Peterson PN.
PMID: 34813771
Am Heart J. 2022 Feb;244:135-148. doi: 10.1016/j.ahj.2021.11.011. Epub 2021 Nov 20.

BACKGROUND: Uninsurance is a known contributor to racial/ethnic health inequities. Insurance is often needed for prescriptions and follow-up appointments. Therefore, we determined whether the Affordable Care Act(ACA) Medicaid Expansion was associated with increased receipt of guideline-directed medical treatment(GDMT) at...

Cost-effectiveness of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab in patients with a history of myocardial infarction in Sweden.

European heart journal. Quality of care & clinical outcomes

Landmesser U, Lindgren P, Hagström E, van Hout B, Villa G, Pemberton-Ross P, Arellano J, Svensson ME, Sibartie M, Fonarow GC.
PMID: 33063111
Eur Heart J Qual Care Clin Outcomes. 2022 Jan 05;8(1):31-38. doi: 10.1093/ehjqcco/qcaa072.

AIMS: To assess the cost-effectiveness of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab added to standard-of-care lipid-lowering treatment [maximum tolerated dose (MTD) of statin and ezetimibe] in Swedish patients with a history of myocardial infarction (MI).METHODS AND RESULTS:...

Cost and Value in Contemporary Heart Failure Clinical Guidance Documents.

JACC. Heart failure

Ostrominski JW, Hirji S, Bhatt AS, Butler J, Fiuzat M, Fonarow GC, Heidenreich PA, Januzzi JL, Lam CSP, Maddox TM, O'Connor CM, Vaduganathan M.
PMID: 34969491
JACC Heart Fail. 2022 Jan;10(1):1-11. doi: 10.1016/j.jchf.2021.08.002. Epub 2021 Nov 10.

OBJECTIVES: This study sought to evaluate the frequency and nature of cost/value statements in contemporary heart failure (HF) clinical guidance documents (CGDs).BACKGROUND: In an era of rising health care costs and expanding therapeutic options, there is an increasing need...

Identifying Treatments for Stage C2 Heart Failure.

JAMA cardiology

Yancy CW, Hernandez AF, Fonarow GC.
PMID: 34643645
JAMA Cardiol. 2022 Jan 01;7(1):34-35. doi: 10.1001/jamacardio.2021.4024.

No abstract available.

Diuretic Changes, Health Care Resource Utilization, and Clinical Outcomes for Heart Failure With Reduced Ejection Fraction: From the Change the Management of Patients With Heart Failure Registry.

Circulation. Heart failure

Khan MS, Greene SJ, Hellkamp AS, DeVore AD, Shen X, Albert NM, Patterson JH, Spertus JA, Thomas LE, Williams FB, Hernandez AF, Fonarow GC, Butler J.
PMID: 34674536
Circ Heart Fail. 2021 Nov;14(11):e008351. doi: 10.1161/CIRCHEARTFAILURE.121.008351. Epub 2021 Oct 22.

BACKGROUND: Diuretics are a mainstay therapy for the symptomatic treatment of heart failure. However, in contemporary US outpatient practice, the degree to which diuretic dosing changes over time and the associations with clinical outcomes and health care resource utilization...

Making heart failure count.

European journal of heart failure

Ziaeian B, Fonarow GC.
PMID: 33713517
Eur J Heart Fail. 2021 Jun;23(6):917-918. doi: 10.1002/ejhf.2148. Epub 2021 Mar 18.

No abstract available.

Projected Clinical Benefits of Implementation of SGLT-2 Inhibitors among Medicare Beneficiaries Hospitalized for Heart Failure.

Journal of cardiac failure

Vaduganathan M, Greene SJ, Zhang S, Solomon N, Chiswell K, DeVore AD, Butler J, Heidenreich PA, Huang JC, Kittleson MM, Maddox KEJ, McDermott JJ, Owens AT, Peterson PN, Solomon SD, Vardeny O, Yancy CW, Fonarow GC.
PMID: 34785402
J Card Fail. 2021 Nov 13; doi: 10.1016/j.cardfail.2021.11.010. Epub 2021 Nov 13.

BACKGROUND: The sodium-glucose cotransporter-2 (SGLT-2) inhibitors form the latest pillar in the management of heart failure with reduced ejection fraction (HFrEF) and appear effective across a range of patient profiles. There is increasing interest around initiation of SGLT-2 inhibitor...

A Brief Overview of Recurrent Pericarditis Management and the Potential of Rilonacept as a New Therapeutic Option.

American journal of cardiovascular drugs : drugs, devices, and other interventions

Gupta M, Kaul S, Velazquez GR, Bandyopadhyay D, Fonarow GC, Klein A, Ghosh RK.
PMID: 34008144
Am J Cardiovasc Drugs. 2022 Jan;22(1):27-33. doi: 10.1007/s40256-021-00481-x. Epub 2021 May 19.

Recurrent pericarditis affects 15-30% of patients after acute pericarditis. A large number of the patients with recurrent pericarditis can become corticosteroid dependent, leading to disease chronicity and drug dependence, with additional morbidity from long-term steroid use. Recent randomized trials...

Potential Implications of Expanded US Food and Drug Administration Labeling for Sacubitril/Valsartan in the US.

JAMA cardiology

Vaduganathan M, Claggett BL, Greene SJ, Aggarwal R, Bhatt AS, McMurray JJV, Fonarow GC, Solomon SD.
PMID: 34524394
JAMA Cardiol. 2021 Sep 15; doi: 10.1001/jamacardio.2021.3651. Epub 2021 Sep 15.

IMPORTANCE: The US Food and Drug Administration (FDA) expanded labeling for sacubitril/valsartan for use in individuals with chronic heart failure (HF) with left ventricular ejection fraction (LVEF) lower than normal. The population-level implications of implementation of sacubitril/valsartan at higher...

Showing 181 to 191 of 191 entries