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Showing 2677 to 2685 of 2685 entries
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Real-World Effectiveness Of Remdesivir In Adults Hospitalized With Covid-19: A Retrospective, Multicenter Comparative Effectiveness Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Garibaldi BT, Wang K, Robinson ML, Betz J, Alexander GC, Andersen KM, Joseph CS, Mehta HB, Korwek K, Sands KE, Fisher AM, Bollinger RC, Xu Y.
PMID: 34910128
Clin Infect Dis. 2021 Dec 15; doi: 10.1093/cid/ciab1035. Epub 2021 Dec 15.

BACKGROUND: There is an urgent need to understand the real-world effectiveness of remdesivir in the treatment of SARS-CoV-2.METHODS: This was a retrospective comparative effectiveness study. Individuals hospitalized in a large private healthcare network in the US from February 23,...

Tandem Therapeutic Plasma Exchange Reduces Continuous Renal Replacement Therapy Downtime.

Blood purification

Foglia MJ, Pelletier JH, Bayir H, Fleck A, Konyk L, McSteen C, Fisher D, Fuhrman DY.
PMID: 34515068
Blood Purif. 2021 Sep 01;1-8. doi: 10.1159/000518348. Epub 2021 Sep 01.

INTRODUCTION: Continuous renal replacement therapy (CRRT) has become a primary treatment of severe acute kidney injury in children admitted to the intensive care unit. CRRT "downtime" (when the circuit is not active) can represent a significant portion of the...

Payload Delivery: Engineering Immune Cells to Disrupt the Tumour Microenvironment.

Cancers

Fowler D, Nattress C, Navarrete AS, Barisa M, Fisher J.
PMID: 34885108
Cancers (Basel). 2021 Nov 29;13(23). doi: 10.3390/cancers13236000.

Although chimeric antigen receptor (CAR) T cells have shown impressive clinical success against haematological malignancies such as B cell lymphoma and acute lymphoblastic leukaemia, their efficacy against non-haematological solid malignancies has been largely disappointing. Solid tumours pose many additional...

Polymorphism of dimethylaminoborane N(CH.

Acta crystallographica Section B, Structural science, crystal engineering and materials

Bodach A, Bernert T, Fischer M, Ley MB, Weidenthaler C.
PMID: 33843738
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2021 Apr 01;77:299-306. doi: 10.1107/S2052520621001979. Epub 2021 Mar 26.

Dehydrocoupling of the adduct of dimethylamine and borane, NH(CH

Innate immune regulates cutaneous sensory IL-13 receptor alpha 2 to promote atopic dermatitis.

Brain, behavior, and immunity

Xiao S, Lu Z, Steinhoff M, Li Y, Buhl T, Fischer M, Chen W, Cheng W, Zhu R, Yan X, Yang H, Liu Y, Dou Y, Wang W, Wang J, Meng J.
PMID: 34391816
Brain Behav Immun. 2021 Nov;98:28-39. doi: 10.1016/j.bbi.2021.08.211. Epub 2021 Aug 13.

The clinical significance and regulators of IL-13Rα2 in itch and atopic dermatitis (AD) remain unclear. To identify disease-driven regulatory circuits of IL-13Rα2, transcriptomic/pathological analysis was performed in skin from patients with AD, psoriasis, healthy subjects, and murine AD model....

Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.

Toxicology in vitro : an international journal published in association with BIBRA

Escher SE, Aguayo-Orozco A, Benfenati E, Bitsch A, Braunbeck T, Brotzmann K, Bois F, van der Burg B, Castel J, Exner T, Gadaleta D, Gardner I, Goldmann D, Hatley O, Golbamaki N, Graepel R, Jennings P, Limonciel A, Long A, Maclennan R, Mombelli E, Norinder U, Jain S, Capinha LS, Taboureau OT, Tolosa L, Vrijenhoek NG, van Vugt-Lussenburg BMA, Walker P, van de Water B, Wehr M, White A, Zdrazil B, Fisher C.
PMID: 34757180
Toxicol In Vitro. 2022 Mar;79:105269. doi: 10.1016/j.tiv.2021.105269. Epub 2021 Oct 29.

Read-across approaches often remain inconclusive as they do not provide sufficient evidence on a common mode of action across the category members. This read-across case study on thirteen, structurally similar, branched aliphatic carboxylic acids investigates the concept of using...

Computer Science, Biology and Biomedical Informatics academy: Outcomes from 5 years of Immersing High-school Students into Informatics Research.

Becich MJ, King AJ, Fisher AM, Boone DN.
UIID-AD: 4383
2017; doi: 10.4103/2153-3539.201110.

The University of Pittsburgh's Department of Biomedical Informatics and Division of Pathology Informatics created a Science, Technology, Engineering, and Mathematics (STEM) pipeline in 2011 dedicated to providing cutting-edge informatics research and career preparatory experiences to a diverse group of...

Building a pipeline of training for behavioral diabetes researchers and clinicians: a call for national dialogue.

de Groot M, Fisher L.
UIID-AD: 2695
2011;11:503-10. doi: 10.1007/s11892-011-0231-x.

In the context of a diabetes epidemic and health care workforce crisis in the United States, a national dialogue is needed to identify the pathways and mechanisms for training a cohort of behavioral diabetes researchers and clinicians. Over the...

Differences in STEM doctoral publication by ethnicity, gender and academic field at a large public research university.

Smith A, Mendoza-Denton R, Patt C, Fisher A, Eppig A, Young I, Richards MA.
UIID-AD: 4388
2017; doi: 10.1371/journal.pone.0174296.

Two independent surveys of PhD students in STEM fields at the University of California, Berkeley, indicate that underrepresented minorities (URMs) publish at significantly lower rates than non-URM males, placing the former at a significant disadvantage as they compete for...

Showing 2677 to 2685 of 2685 entries