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Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study.

Oncotarget

Soave A, Chun FK, Hillebrand T, Rink M, Weisbach L, Steinbach B, Fisch M, Pantel K, Schwarzenbach H.
PMID: 28915599
Oncotarget. 2017 May 07;8(34):56398-56407. doi: 10.18632/oncotarget.17657. eCollection 2017 Aug 22.

The aim of the present study was to establish a rapid profiling method using multiplex ligation-dependent probe amplification (MLPA) and characterize copy number variations (CNV) in circulating, cell-free DNA (cfDNA) in 85 urothelial carcinoma of the bladder (UCB) patients...

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Soave A, Chun FK, Hillebrand T, et al. Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study. Oncotarget. 2017;8(34):56398-56407doi: 10.18632/oncotarget.17657.
Soave, A., Chun, F. K., Hillebrand, T., Rink, M., Weisbach, L., Steinbach, B., Fisch, M., Pantel, K., & Schwarzenbach, H. (2017). Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study. Oncotarget, 8(34), 56398-56407. https://doi.org/10.18632/oncotarget.17657
Soave, Armin, et al. "Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study." Oncotarget vol. 8,34 (2017): 56398-56407. doi: https://doi.org/10.18632/oncotarget.17657
Soave A, Chun FK, Hillebrand T, Rink M, Weisbach L, Steinbach B, Fisch M, Pantel K, Schwarzenbach H. Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study. Oncotarget. 2017 May 07;8(34):56398-56407. doi: 10.18632/oncotarget.17657. eCollection 2017 Aug 22. PMID: 28915599; PMCID: PMC5593570.
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BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.

Journal of cellular biochemistry

Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW.
PMID: 30417424
J Cell Biochem. 2018 Nov 11; doi: 10.1002/jcb.28005. Epub 2018 Nov 11.

Inhibitors of the bromodomain and extraterminal domain family (BETi) offer a new approach to treat hematological malignancies, with leukemias containing mixed lineage leukemia rearrangements being especially sensitive due to a reliance on the regulation of transcription elongation. We explored...

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Zhang S, Zhao Y, Heaster TM, et al. BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML. J Cell Biochem. 2018;doi: 10.1002/jcb.28005.
Zhang, S., Zhao, Y., Heaster, T. M., Fischer, M. A., Stengel, K. R., Zhou, X., Ramsey, H., Zhou, M. M., Savona, M. R., Skala, M. C., & Hiebert, S. W. (2018). BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML. Journal of cellular biochemistry, . https://doi.org/10.1002/jcb.28005
Zhang, Susu, et al. "BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML." Journal of cellular biochemistry vol. (2018). doi: https://doi.org/10.1002/jcb.28005
Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML. J Cell Biochem. 2018 Nov 11; doi: 10.1002/jcb.28005. Epub 2018 Nov 11. PMID: 30417424; PMCID: PMC6513713.
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Polychlorinated Biphenyl (PCB)-Degrading Potential of Microbes Present in a Cryoconite of Jamtalferner Glacier.

Frontiers in microbiology

Weiland-Bräuer N, Fischer MA, Schramm KW, Schmitz RA.
PMID: 28663747
Front Microbiol. 2017 Jun 15;8:1105. doi: 10.3389/fmicb.2017.01105. eCollection 2017.

Aiming to comprehensively survey the potential pollution of an alpine cryoconite (Jamtalferner glacier, Austria), and its bacterial community structure along with its biodegrading potential, first chemical analyses of persistent organic pollutants, explicitly polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs)...

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Weiland-Bräuer N, Fischer MA, Schramm KW, et al. Polychlorinated Biphenyl (PCB)-Degrading Potential of Microbes Present in a Cryoconite of Jamtalferner Glacier. Front Microbiol. 2017;8:1105doi: 10.3389/fmicb.2017.01105.
Weiland-Bräuer, N., Fischer, M. A., Schramm, K. W., & Schmitz, R. A. (2017). Polychlorinated Biphenyl (PCB)-Degrading Potential of Microbes Present in a Cryoconite of Jamtalferner Glacier. Frontiers in microbiology, 81105. https://doi.org/10.3389/fmicb.2017.01105
Weiland-Bräuer, Nancy, et al. "Polychlorinated Biphenyl (PCB)-Degrading Potential of Microbes Present in a Cryoconite of Jamtalferner Glacier." Frontiers in microbiology vol. 8 (2017): 1105. doi: https://doi.org/10.3389/fmicb.2017.01105
Weiland-Bräuer N, Fischer MA, Schramm KW, Schmitz RA. Polychlorinated Biphenyl (PCB)-Degrading Potential of Microbes Present in a Cryoconite of Jamtalferner Glacier. Front Microbiol. 2017 Jun 15;8:1105. doi: 10.3389/fmicb.2017.01105. eCollection 2017. PMID: 28663747; PMCID: PMC5471330.
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A Fast Approach to Automatic Detection of Brain Lesions.

Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop)

Koley S, Chakraborty C, Mainero C, Fischl B, Aganj I.
PMID: 29082383
Brainlesion. 2016;10154:52-61. doi: 10.1007/978-3-319-55524-9_6. Epub 2017 Apr 12.

Template matching is a popular approach to computer-aided detection of brain lesions from magnetic resonance (MR) images. The outcomes are often sufficient for localizing lesions and assisting clinicians in diagnosis. However, processing large MR volumes with three-dimensional (3D) templates...

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Koley S, Chakraborty C, Mainero C, et al. A Fast Approach to Automatic Detection of Brain Lesions. Brainlesion. 2017;10154:52-61doi: 10.1007/978-3-319-55524-9_6.
Koley, S., Chakraborty, C., Mainero, C., Fischl, B., & Aganj, I. (2016). A Fast Approach to Automatic Detection of Brain Lesions. Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop), 1015452-61. https://doi.org/10.1007/978-3-319-55524-9_6
Koley, Subhranil, et al. "A Fast Approach to Automatic Detection of Brain Lesions." Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop) vol. 10154 (2016): 52-61. doi: https://doi.org/10.1007/978-3-319-55524-9_6
Koley S, Chakraborty C, Mainero C, Fischl B, Aganj I. A Fast Approach to Automatic Detection of Brain Lesions. Brainlesion. 2016;10154:52-61. doi: 10.1007/978-3-319-55524-9_6. Epub 2017 Apr 12. PMID: 29082383; PMCID: PMC5654618.
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A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data.

Pragmatic and observational research

Kern DM, Barron JJ, Wu B, Ganetsky A, Willey VJ, Quimbo RA, Fisch MJ, Singer J, Nguyen A, Mamtani R.
PMID: 28894396
Pragmat Obs Res. 2017 Aug 26;8:149-155. doi: 10.2147/POR.S140579. eCollection 2017.

BACKGROUND: Data from a Cancer Care Quality Program are directly integrated with administrative claims data to provide a level of clinical detail not available in claims-based studies, and referred to as the HealthCore Integrated Research Environment (HIRE)-Oncology data. This...

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Kern DM, Barron JJ, Wu B, et al. A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data. Pragmat Obs Res. 2017;8:149-155doi: 10.2147/POR.S140579.
Kern, D. M., Barron, J. J., Wu, B., Ganetsky, A., Willey, V. J., Quimbo, R. A., Fisch, M. J., Singer, J., Nguyen, A., & Mamtani, R. (2017). A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data. Pragmatic and observational research, 8149-155. https://doi.org/10.2147/POR.S140579
Kern, David M, et al. "A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data." Pragmatic and observational research vol. 8 (2017): 149-155. doi: https://doi.org/10.2147/POR.S140579
Kern DM, Barron JJ, Wu B, Ganetsky A, Willey VJ, Quimbo RA, Fisch MJ, Singer J, Nguyen A, Mamtani R. A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data. Pragmat Obs Res. 2017 Aug 26;8:149-155. doi: 10.2147/POR.S140579. eCollection 2017. PMID: 28894396; PMCID: PMC5584892.
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Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography.

Biomedical optics express

Wang H, Magnain C, Sakadžić S, Fischl B, Boas DA.
PMID: 29296492
Biomed Opt Express. 2017 Nov 14;8(12):5617-5636. doi: 10.1364/BOE.8.005617. eCollection 2017 Dec 01.

Quantification of tissue optical properties with optical coherence tomography (OCT) has proven to be useful in evaluating structural characteristics and pathological changes. Previous studies primarily used an exponential model to analyze low numerical aperture (NA) OCT measurements and obtain...

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Wang H, Magnain C, Sakadžić S, et al. Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography. Biomed Opt Express. 2017;8(12):5617-5636doi: 10.1364/BOE.8.005617.
Wang, H., Magnain, C., Sakadžić, S., Fischl, B., & Boas, D. A. (2017). Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography. Biomedical optics express, 8(12), 5617-5636. https://doi.org/10.1364/BOE.8.005617
Wang, Hui, et al. "Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography." Biomedical optics express vol. 8,12 (2017): 5617-5636. doi: https://doi.org/10.1364/BOE.8.005617
Wang H, Magnain C, Sakadžić S, Fischl B, Boas DA. Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography. Biomed Opt Express. 2017 Nov 14;8(12):5617-5636. doi: 10.1364/BOE.8.005617. eCollection 2017 Dec 01. PMID: 29296492; PMCID: PMC5745107.
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Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial.

Cancer management and research

Rich T, Zhao F, Cruciani RA, Cella D, Manola J, Fisch MJ.
PMID: 28203105
Cancer Manag Res. 2017 Jan 31;9:1-10. doi: 10.2147/CMAR.S115835. eCollection 2017.

CONTEXT: The biology of fatigue and depression in cancer patients is poorly understood. Hypotheses regarding cytokines and growth factors related to sickness behavior and disruption of circadian signaling have been proposed.OBJECTIVES: We prospectively examined proinflammatory cytokines (e.g., sickness behavior...

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Rich T, Zhao F, Cruciani RA, et al. Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial. Cancer Manag Res. 2017;9:1-10doi: 10.2147/CMAR.S115835.
Rich, T., Zhao, F., Cruciani, R. A., Cella, D., Manola, J., & Fisch, M. J. (2017). Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial. Cancer management and research, 91-10. https://doi.org/10.2147/CMAR.S115835
Rich, Tyvin, et al. "Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial." Cancer management and research vol. 9 (2017): 1-10. doi: https://doi.org/10.2147/CMAR.S115835
Rich T, Zhao F, Cruciani RA, Cella D, Manola J, Fisch MJ. Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial. Cancer Manag Res. 2017 Jan 31;9:1-10. doi: 10.2147/CMAR.S115835. eCollection 2017. PMID: 28203105; PMCID: PMC5295802.
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Nasal IgE in subjects with allergic and non-allergic rhinitis.

The World Allergy Organization journal

Eckrich J, Hinkel J, Fischl A, Herrmann E, Holtappels G, Bachert C, Zielen S.
PMID: 32612737
World Allergy Organ J. 2020 Jun 23;13(6):100129. doi: 10.1016/j.waojou.2020.100129. eCollection 2020 Jun.

PURPOSE: The prevalence of "ocal allergic rhinitis" within individuals suffering from perennial rhinitis remains uncertain, and patients usually are diagnosed with non-allergic rhinitis. The aim of this study was to evaluate the prevalence of a potential "local allergic rhinitis"...

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Eckrich J, Hinkel J, Fischl A, et al. Nasal IgE in subjects with allergic and non-allergic rhinitis. World Allergy Organ J. 2020;13(6):100129doi: 10.1016/j.waojou.2020.100129.
Eckrich, J., Hinkel, J., Fischl, A., Herrmann, E., Holtappels, G., Bachert, C., & Zielen, S. (2020). Nasal IgE in subjects with allergic and non-allergic rhinitis. The World Allergy Organization journal, 13(6), 100129. https://doi.org/10.1016/j.waojou.2020.100129
Eckrich, Jonas, et al. "Nasal IgE in subjects with allergic and non-allergic rhinitis." The World Allergy Organization journal vol. 13,6 (2020): 100129. doi: https://doi.org/10.1016/j.waojou.2020.100129
Eckrich J, Hinkel J, Fischl A, Herrmann E, Holtappels G, Bachert C, Zielen S. Nasal IgE in subjects with allergic and non-allergic rhinitis. World Allergy Organ J. 2020 Jun 23;13(6):100129. doi: 10.1016/j.waojou.2020.100129. eCollection 2020 Jun. PMID: 32612737; PMCID: PMC7322186.
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Immediate Effects of Ammonia Shock on Transcription and Composition of a Biogas Reactor Microbiome.

Frontiers in microbiology

Fischer MA, Ulbricht A, Neulinger SC, Refai S, Waßmann K, Künzel S, Schmitz RA.
PMID: 31555248
Front Microbiol. 2019 Sep 06;10:2064. doi: 10.3389/fmicb.2019.02064. eCollection 2019.

The biotechnological process of biogas production from organic material is carried out by a diverse microbial community under anaerobic conditions. However, the complex and sensitive microbial network present in anaerobic degradation of organic material can be disturbed by increased...

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Fischer MA, Ulbricht A, Neulinger SC, et al. Immediate Effects of Ammonia Shock on Transcription and Composition of a Biogas Reactor Microbiome. Front Microbiol. 2019;10:2064doi: 10.3389/fmicb.2019.02064.
Fischer, M. A., Ulbricht, A., Neulinger, S. C., Refai, S., Waßmann, K., Künzel, S., & Schmitz, R. A. (2019). Immediate Effects of Ammonia Shock on Transcription and Composition of a Biogas Reactor Microbiome. Frontiers in microbiology, 102064. https://doi.org/10.3389/fmicb.2019.02064
Fischer, Martin A, et al. "Immediate Effects of Ammonia Shock on Transcription and Composition of a Biogas Reactor Microbiome." Frontiers in microbiology vol. 10 (2019): 2064. doi: https://doi.org/10.3389/fmicb.2019.02064
Fischer MA, Ulbricht A, Neulinger SC, Refai S, Waßmann K, Künzel S, Schmitz RA. Immediate Effects of Ammonia Shock on Transcription and Composition of a Biogas Reactor Microbiome. Front Microbiol. 2019 Sep 06;10:2064. doi: 10.3389/fmicb.2019.02064. eCollection 2019. PMID: 31555248; PMCID: PMC6742706.
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Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology.

JACC. CardioOncology

Alvarez-Cardona JA, Zhang KW, Mitchell JD, Zaha VG, Fisch MJ, Lenihan DJ.
PMID: 34396295
JACC CardioOncol. 2020 Dec 15;2(5):791-794. doi: 10.1016/j.jaccao.2020.08.014. eCollection 2020 Dec.

No abstract available.

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Alvarez-Cardona JA, Zhang KW, Mitchell JD, et al. Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology. JACC CardioOncol. 2020;2(5):791-794doi: 10.1016/j.jaccao.2020.08.014.
Alvarez-Cardona, J. A., Zhang, K. W., Mitchell, J. D., Zaha, V. G., Fisch, M. J., & Lenihan, D. J. (2020). Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology. JACC. CardioOncology, 2(5), 791-794. https://doi.org/10.1016/j.jaccao.2020.08.014
Alvarez-Cardona, Jose A, et al. "Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology." JACC. CardioOncology vol. 2,5 (2020): 791-794. doi: https://doi.org/10.1016/j.jaccao.2020.08.014
Alvarez-Cardona JA, Zhang KW, Mitchell JD, Zaha VG, Fisch MJ, Lenihan DJ. Cardiac Biomarkers During Cancer Therapy: Practical Applications for Cardio-Oncology. JACC CardioOncol. 2020 Dec 15;2(5):791-794. doi: 10.1016/j.jaccao.2020.08.014. eCollection 2020 Dec. PMID: 34396295; PMCID: PMC8352269.
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Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.

International journal of molecular sciences

Ibrahim HS, Abdelsalam M, Zeyn Y, Zessin M, Mustafa AM, Fischer MA, Zeyen P, Sun P, Bülbül EF, Vecchio A, Erdmann F, Schmidt M, Robaa D, Barinka C, Romier C, Schutkowski M, Krämer OH, Sippl W.
PMID: 35008795
Int J Mol Sci. 2021 Dec 29;23(1). doi: 10.3390/ijms23010369.

Class I histone deacetylases (HDACs) are key regulators of cell proliferation and they are frequently dysregulated in cancer cells. We report here the synthesis of a novel series of class-I selective HDAC inhibitors (HDACi) containing a 2-aminobenzamide moiety as...

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Ibrahim HS, Abdelsalam M, Zeyn Y, et al. Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity. Int J Mol Sci. 2021;23(1)doi: 10.3390/ijms23010369.
Ibrahim, H. S., Abdelsalam, M., Zeyn, Y., Zessin, M., Mustafa, A. M., Fischer, M. A., Zeyen, P., Sun, P., Bülbül, E. F., Vecchio, A., Erdmann, F., Schmidt, M., Robaa, D., Barinka, C., Romier, C., Schutkowski, M., Krämer, O. H., & Sippl, W. (2021). Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity. International journal of molecular sciences, 23(1), . https://doi.org/10.3390/ijms23010369
Ibrahim, Hany S, et al. "Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity." International journal of molecular sciences vol. 23,1 (2021). doi: https://doi.org/10.3390/ijms23010369
Ibrahim HS, Abdelsalam M, Zeyn Y, Zessin M, Mustafa AM, Fischer MA, Zeyen P, Sun P, Bülbül EF, Vecchio A, Erdmann F, Schmidt M, Robaa D, Barinka C, Romier C, Schutkowski M, Krämer OH, Sippl W. Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity. Int J Mol Sci. 2021 Dec 29;23(1). doi: 10.3390/ijms23010369. PMID: 35008795.
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Stopping Gestational Diabetes in American Indian and Alaska Native Girls: Nutrition as a Key Component to Gestational Diabetes Risk Reduction.

Current developments in nutrition

Stotz SA, Charron-Prochownik D, Terry MA, Marshall G, Fischl AR, Moore KR.
PMID: 34222764
Curr Dev Nutr. 2020 May 06;5:13-21. doi: 10.1093/cdn/nzaa081. eCollection 2021 Jun.

BACKGROUND: American Indian and Alaska Native (AI/AN) women have a higher risk of gestational diabetes mellitus (GDM) and subsequent diagnosis of diabetes than do non-Hispanic White women. Healthy eating is key to weight management both prior to pregnancy and...

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Stotz SA, Charron-Prochownik D, Terry MA, et al. Stopping Gestational Diabetes in American Indian and Alaska Native Girls: Nutrition as a Key Component to Gestational Diabetes Risk Reduction. Curr Dev Nutr. 2020;5:13-21doi: 10.1093/cdn/nzaa081.
Stotz, S. A., Charron-Prochownik, D., Terry, M. A., Marshall, G., Fischl, A. R., Moore, K. R. (2021). Stopping Gestational Diabetes in American Indian and Alaska Native Girls: Nutrition as a Key Component to Gestational Diabetes Risk Reduction. Current developments in nutrition, 513-21. https://doi.org/10.1093/cdn/nzaa081
Stotz, Sarah A, et al. "Stopping Gestational Diabetes in American Indian and Alaska Native Girls: Nutrition as a Key Component to Gestational Diabetes Risk Reduction." Current developments in nutrition vol. 5 (2021): 13-21. doi: https://doi.org/10.1093/cdn/nzaa081
Stotz SA, Charron-Prochownik D, Terry MA, Marshall G, Fischl AR, Moore KR. Stopping Gestational Diabetes in American Indian and Alaska Native Girls: Nutrition as a Key Component to Gestational Diabetes Risk Reduction. Curr Dev Nutr. 2020 May 06;5:13-21. doi: 10.1093/cdn/nzaa081. eCollection 2021 Jun. PMID: 34222764; PMCID: PMC8242493.
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