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Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R.
PMID: 34569707
Alzheimers Dement. 2021 Sep 27; doi: 10.1002/alz.12465. Epub 2021 Sep 27.

INTRODUCTION: Tumor necrosis factor (TNF) inhibitors are widely used to treat rheumatoid arthritis (RA) and their potential to retard Alzheimer's disease (AD) progression has been reported. However, their long-term effects on the dementia/AD risk remain unknown.METHODS: A propensity scored...

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Zheng C, Fillmore NR, Ramos-Cejudo J, et al. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2021;doi: 10.1002/alz.12465.
Zheng, C., Fillmore, N. R., Ramos-Cejudo, J., Brophy, M., Osorio, R., Gurney, M. E., Qiu, W. Q., Au, R., Perry, G., Dubreuil, M., Chen, S. G., Qi, X., Davis, P. B., Do, N., & Xu, R. (2021). Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12465
Zheng, Chunlei, et al. "Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12465
Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2021 Sep 27; doi: 10.1002/alz.12465. Epub 2021 Sep 27. PMID: 34569707.
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Evaluating the impact of age on immune checkpoint therapy biomarkers.

Cell reports

Erbe R, Wang Z, Wu S, Xiu J, Zaidi N, La J, Tuck D, Fillmore N, Giraldo NA, Topper M, Baylin S, Lippman M, Isaacs C, Basho R, Serebriiskii I, Lenz HJ, Astsaturov I, Marshall J, Taverna J, Lee J, Jaffee EM, Roussos Torres ET, Weeraratna A, Easwaran H, Fertig EJ.
PMID: 34433020
Cell Rep. 2021 Aug 24;36(8):109599. doi: 10.1016/j.celrep.2021.109599.

Both tumors and aging alter the immune landscape of tissues. These interactions may play an important role in tumor progression among elderly patients and may suggest considerations for patient care. We leverage large-scale genomic and clinical databases to perform...

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Erbe R, Wang Z, Wu S, et al. Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell Rep. 2021;36(8):109599doi: 10.1016/j.celrep.2021.109599.
Erbe, R., Wang, Z., Wu, S., Xiu, J., Zaidi, N., La, J., Tuck, D., Fillmore, N., Giraldo, N. A., Topper, M., Baylin, S., Lippman, M., Isaacs, C., Basho, R., Serebriiskii, I., Lenz, H. J., Astsaturov, I., Marshall, J., Taverna, J., Lee, J., Jaffee, E. M., Roussos Torres, E. T., Weeraratna, A., Easwaran, H., & Fertig, E. J. (2021). Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell reports, 36(8), 109599. https://doi.org/10.1016/j.celrep.2021.109599
Erbe, Rossin, et al. "Evaluating the impact of age on immune checkpoint therapy biomarkers." Cell reports vol. 36,8 (2021): 109599. doi: https://doi.org/10.1016/j.celrep.2021.109599
Erbe R, Wang Z, Wu S, Xiu J, Zaidi N, La J, Tuck D, Fillmore N, Giraldo NA, Topper M, Baylin S, Lippman M, Isaacs C, Basho R, Serebriiskii I, Lenz HJ, Astsaturov I, Marshall J, Taverna J, Lee J, Jaffee EM, Roussos Torres ET, Weeraratna A, Easwaran H, Fertig EJ. Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell Rep. 2021 Aug 24;36(8):109599. doi: 10.1016/j.celrep.2021.109599. PMID: 34433020.
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Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins.

Oncotarget

Shi T, Quek SI, Gao Y, Nicora CD, Nie S, Fillmore TL, Liu T, Rodland KD, Smith RD, Leach RJ, Thompson IM, Vitello EA, Ellis WJ, Liu AY, Qian WJ.
PMID: 29254211
Oncotarget. 2017 Oct 09;8(60):101887-101898. doi: 10.18632/oncotarget.21710. eCollection 2017 Nov 24.

Biomarkers for effective early diagnosis and prognosis of prostate cancer are still lacking. Multiplexed assays for cancer-associated proteins could be useful for identifying biomarkers for cancer detection and stratification. Herein, we report the development of sensitive targeted mass spectrometry...

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Shi T, Quek SI, Gao Y, et al. Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins. Oncotarget. 2017;8(60):101887-101898doi: 10.18632/oncotarget.21710.
Shi, T., Quek, S. I., Gao, Y., Nicora, C. D., Nie, S., Fillmore, T. L., Liu, T., Rodland, K. D., Smith, R. D., Leach, R. J., Thompson, I. M., Vitello, E. A., Ellis, W. J., Liu, A. Y., & Qian, W. J. (2017). Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins. Oncotarget, 8(60), 101887-101898. https://doi.org/10.18632/oncotarget.21710
Shi, Tujin, et al. "Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins." Oncotarget vol. 8,60 (2017): 101887-101898. doi: https://doi.org/10.18632/oncotarget.21710
Shi T, Quek SI, Gao Y, Nicora CD, Nie S, Fillmore TL, Liu T, Rodland KD, Smith RD, Leach RJ, Thompson IM, Vitello EA, Ellis WJ, Liu AY, Qian WJ. Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins. Oncotarget. 2017 Oct 09;8(60):101887-101898. doi: 10.18632/oncotarget.21710. eCollection 2017 Nov 24. PMID: 29254211; PMCID: PMC5731921.
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Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria.

AMB Express

Yang E, Fan L, Yan J, Jiang Y, Doucette C, Fillmore S, Walker B.
PMID: 29368243
AMB Express. 2018 Jan 24;8(1):10. doi: 10.1186/s13568-018-0536-0.

There has been continued interest in bacteriocins research from an applied perspective as bacteriocins have potential to be used as natural preservative. Four bacteriocinogenic lactic acid bacteria (LAB) strains of Lactobacillus curvatus (Arla-10), Enterococcus faecium (JFR-1), Lactobacillus paracasei subsp....

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Yang E, Fan L, Yan J, et al. Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria. AMB Express. 2018;8(1):10doi: 10.1186/s13568-018-0536-0.
Yang, E., Fan, L., Yan, J., Jiang, Y., Doucette, C., Fillmore, S., & Walker, B. (2018). Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria. AMB Express, 8(1), 10. https://doi.org/10.1186/s13568-018-0536-0
Yang, En, et al. "Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria." AMB Express vol. 8,1 (2018): 10. doi: https://doi.org/10.1186/s13568-018-0536-0
Yang E, Fan L, Yan J, Jiang Y, Doucette C, Fillmore S, Walker B. Influence of culture media, pH and temperature on growth and bacteriocin production of bacteriocinogenic lactic acid bacteria. AMB Express. 2018 Jan 24;8(1):10. doi: 10.1186/s13568-018-0536-0. PMID: 29368243; PMCID: PMC5783981.
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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance.

Cancer cell

Joshi SK, Nechiporuk T, Bottomly D, Piehowski PD, Reisz JA, Pittsenbarger J, Kaempf A, Gosline SJC, Wang YT, Hansen JR, Gritsenko MA, Hutchinson C, Weitz KK, Moon J, Cendali F, Fillmore TL, Tsai CF, Schepmoes AA, Shi T, Arshad OA, McDermott JE, Babur O, Watanabe-Smith K, Demir E, D'Alessandro A, Liu T, Tognon CE, Tyner JW, McWeeney SK, Rodland KD, Druker BJ, Traer E.
PMID: 34171263
Cancer Cell. 2021 Jul 12;39(7):999-1014.e8. doi: 10.1016/j.ccell.2021.06.003. Epub 2021 Jun 24.

Our study details the stepwise evolution of gilteritinib resistance in FLT3-mutated acute myeloid leukemia (AML). Early resistance is mediated by the bone marrow microenvironment, which protects residual leukemia cells. Over time, leukemia cells evolve intrinsic mechanisms of resistance, or...

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Joshi SK, Nechiporuk T, Bottomly D, et al. The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance. Cancer Cell. 2021;39(7):999-1014.e8doi: 10.1016/j.ccell.2021.06.003.
Joshi, S. K., Nechiporuk, T., Bottomly, D., Piehowski, P. D., Reisz, J. A., Pittsenbarger, J., Kaempf, A., Gosline, S. J. C., Wang, Y. T., Hansen, J. R., Gritsenko, M. A., Hutchinson, C., Weitz, K. K., Moon, J., Cendali, F., Fillmore, T. L., Tsai, C. F., Schepmoes, A. A., Shi, T., Arshad, O. A., McDermott, J. E., Babur, O., Watanabe-Smith, K., Demir, E., D'Alessandro, A., Liu, T., Tognon, C. E., Tyner, J. W., McWeeney, S. K., Rodland, K. D., Druker, B. J., & Traer, E. (2021). The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance. Cancer cell, 39(7), 999-1014.e8. https://doi.org/10.1016/j.ccell.2021.06.003
Joshi, Sunil K, et al. "The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance." Cancer cell vol. 39,7 (2021): 999-1014.e8. doi: https://doi.org/10.1016/j.ccell.2021.06.003
Joshi SK, Nechiporuk T, Bottomly D, Piehowski PD, Reisz JA, Pittsenbarger J, Kaempf A, Gosline SJC, Wang YT, Hansen JR, Gritsenko MA, Hutchinson C, Weitz KK, Moon J, Cendali F, Fillmore TL, Tsai CF, Schepmoes AA, Shi T, Arshad OA, McDermott JE, Babur O, Watanabe-Smith K, Demir E, D'Alessandro A, Liu T, Tognon CE, Tyner JW, McWeeney SK, Rodland KD, Druker BJ, Traer E. The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance. Cancer Cell. 2021 Jul 12;39(7):999-1014.e8. doi: 10.1016/j.ccell.2021.06.003. Epub 2021 Jun 24. PMID: 34171263.
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The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database.

Patterns (New York, N.Y.)

Elbers DC, Fillmore NR, Sung FC, Ganas SS, Prokhorenkov A, Meyer C, Hall RB, Ajjarapu SJ, Chen DC, Meng F, Grossman RL, Brophy MT, Do NV.
PMID: 33205130
Patterns (N Y). 2020 Aug 17;1(6):100083. doi: 10.1016/j.patter.2020.100083. eCollection 2020 Sep 11.

The Veterans Affairs Precision Oncology Data Repository (VA-PODR) is a large, nationwide repository of de-identified data on patients diagnosed with cancer at the Department of Veterans Affairs (VA). Data include longitudinal clinical data from the VA's nationwide electronic health...

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Elbers DC, Fillmore NR, Sung FC, et al. The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database. Patterns (N Y). 2020;1(6):100083doi: 10.1016/j.patter.2020.100083.
Elbers, D. C., Fillmore, N. R., Sung, F. C., Ganas, S. S., Prokhorenkov, A., Meyer, C., Hall, R. B., Ajjarapu, S. J., Chen, D. C., Meng, F., Grossman, R. L., Brophy, M. T., & Do, N. V. (2020). The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database. Patterns (New York, N.Y.), 1(6), 100083. https://doi.org/10.1016/j.patter.2020.100083
Elbers, Danne C, et al. "The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database." Patterns (New York, N.Y.) vol. 1,6 (2020): 100083. doi: https://doi.org/10.1016/j.patter.2020.100083
Elbers DC, Fillmore NR, Sung FC, Ganas SS, Prokhorenkov A, Meyer C, Hall RB, Ajjarapu SJ, Chen DC, Meng F, Grossman RL, Brophy MT, Do NV. The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database. Patterns (N Y). 2020 Aug 17;1(6):100083. doi: 10.1016/j.patter.2020.100083. eCollection 2020 Sep 11. PMID: 33205130; PMCID: PMC7660389.
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UK Healthcare Workers' Experiences of Major System Change in Elective Surgery During the COVID-19 Pandemic: Reflections on Rapid Service Adaptation.

International journal of health policy and management

Singleton G, Dowrick A, Manby L, Fillmore H, Syverson A, Lewis-Jackson S, Uddin I, Sumray K, Bautista-González E, Johnson G, Vindrola-Padros C.
PMID: 34523860
Int J Health Policy Manag. 2021 Sep 01; doi: 10.34172/ijhpm.2021.101. Epub 2021 Sep 01.

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic disrupted the delivery of elective surgery in the United Kingdom. The majority of planned surgery was cancelled or postponed in March 2020 for the duration of the first wave of the pandemic....

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Singleton G, Dowrick A, Manby L, et al. UK Healthcare Workers' Experiences of Major System Change in Elective Surgery During the COVID-19 Pandemic: Reflections on Rapid Service Adaptation. Int J Health Policy Manag. 2021;doi: 10.34172/ijhpm.2021.101.
Singleton, G., Dowrick, A., Manby, L., Fillmore, H., Syverson, A., Lewis-Jackson, S., Uddin, I., Sumray, K., Bautista-González, E., Johnson, G., & Vindrola-Padros, C. (2021). UK Healthcare Workers' Experiences of Major System Change in Elective Surgery During the COVID-19 Pandemic: Reflections on Rapid Service Adaptation. International journal of health policy and management, . https://doi.org/10.34172/ijhpm.2021.101
Singleton, Georgina, et al. "UK Healthcare Workers' Experiences of Major System Change in Elective Surgery During the COVID-19 Pandemic: Reflections on Rapid Service Adaptation." International journal of health policy and management vol. (2021). doi: https://doi.org/10.34172/ijhpm.2021.101
Singleton G, Dowrick A, Manby L, Fillmore H, Syverson A, Lewis-Jackson S, Uddin I, Sumray K, Bautista-González E, Johnson G, Vindrola-Padros C. UK Healthcare Workers' Experiences of Major System Change in Elective Surgery During the COVID-19 Pandemic: Reflections on Rapid Service Adaptation. Int J Health Policy Manag. 2021 Sep 01; doi: 10.34172/ijhpm.2021.101. Epub 2021 Sep 01. PMID: 34523860.
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Evaluating the impact of age on immune checkpoint therapy biomarkers.

Cell reports

Erbe R, Wang Z, Wu S, Xiu J, Zaidi N, La J, Tuck D, Fillmore N, Giraldo NA, Topper M, Baylin S, Lippman M, Isaacs C, Basho R, Serebriiskii I, Lenz HJ, Astsaturov I, Marshall J, Taverna J, Lee J, Jaffee EM, Roussos Torres ET, Weeraratna A, Easwaran H, Fertig EJ.
PMID: 34433020
Cell Rep. 2021 Aug 24;36(8):109599. doi: 10.1016/j.celrep.2021.109599.

Both tumors and aging alter the immune landscape of tissues. These interactions may play an important role in tumor progression among elderly patients and may suggest considerations for patient care. We leverage large-scale genomic and clinical databases to perform...

Cite
Erbe R, Wang Z, Wu S, et al. Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell Rep. 2021;36(8):109599doi: 10.1016/j.celrep.2021.109599.
Erbe, R., Wang, Z., Wu, S., Xiu, J., Zaidi, N., La, J., Tuck, D., Fillmore, N., Giraldo, N. A., Topper, M., Baylin, S., Lippman, M., Isaacs, C., Basho, R., Serebriiskii, I., Lenz, H. J., Astsaturov, I., Marshall, J., Taverna, J., Lee, J., Jaffee, E. M., Roussos Torres, E. T., Weeraratna, A., Easwaran, H., & Fertig, E. J. (2021). Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell reports, 36(8), 109599. https://doi.org/10.1016/j.celrep.2021.109599
Erbe, Rossin, et al. "Evaluating the impact of age on immune checkpoint therapy biomarkers." Cell reports vol. 36,8 (2021): 109599. doi: https://doi.org/10.1016/j.celrep.2021.109599
Erbe R, Wang Z, Wu S, Xiu J, Zaidi N, La J, Tuck D, Fillmore N, Giraldo NA, Topper M, Baylin S, Lippman M, Isaacs C, Basho R, Serebriiskii I, Lenz HJ, Astsaturov I, Marshall J, Taverna J, Lee J, Jaffee EM, Roussos Torres ET, Weeraratna A, Easwaran H, Fertig EJ. Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell Rep. 2021 Aug 24;36(8):109599. doi: 10.1016/j.celrep.2021.109599. PMID: 34433020.
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Showing 73 to 80 of 80 entries