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Showing 13 to 24 of 126 entries
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Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51.

Cell death and differentiation

Manic G, Musella M, Corradi F, Sistigu A, Vitale S, Soliman Abdel Rehim S, Mattiello L, Malacaria E, Galassi C, Signore M, Pallocca M, Scalera S, Goeman F, De Nicola F, Guarracino A, Pennisi R, Antonangeli F, Sperati F, Baiocchi M, Biffoni M, Fanciulli M, Maugeri-Saccà M, Franchitto A, Pichierri P, De Maria R, Vitale I.
PMID: 33531658
Cell Death Differ. 2021 Jul;28(7):2060-2082. doi: 10.1038/s41418-020-00733-4. Epub 2021 Feb 02.

Cancer stem cells (CSCs) are tumor subpopulations driving disease development, progression, relapse and therapy resistance, and their targeting ensures tumor eradication. CSCs display heterogeneous replication stress (RS), but the functionality/relevance of the RS response (RSR) centered on the ATR-CHK1...

Polarimetric imaging microscopy for advanced inspection of vegetal tissues.

Scientific reports

Van Eeckhout A, Garcia-Caurel E, Garnatje T, Escalera JC, Durfort M, Vidal J, Gil JJ, Campos J, Lizana A.
PMID: 33594126
Sci Rep. 2021 Feb 16;11(1):3913. doi: 10.1038/s41598-021-83421-8.

Optical microscopy techniques for plant inspection benefit from the fact that at least one of the multiple properties of light (intensity, phase, wavelength, polarization) may be modified by vegetal tissues. Paradoxically, polarimetric microscopy although being a mature technique in...

Intravenous metoprolol during ongoing STEMI ameliorates markers of ischemic injury: a METOCARD-CNIC trial electrocardiographic study.

Basic research in cardiology

Díaz-Munoz R, Valle-Caballero MJ, Sanchez-Gonzalez J, Pizarro G, García-Rubira JC, Escalera N, Fuster V, Fernández-Jiménez R, Ibanez B.
PMID: 34279726
Basic Res Cardiol. 2021 Jul 19;116(1):45. doi: 10.1007/s00395-021-00884-6.

Besides its protective effect against neutrophil-mediated injury at reperfusion, intravenous (IV) metoprolol was recently shown to reduce the progression of ischemic injury in a pig model of ST-segment elevation myocardial infarction (STEMI). Here, we tested the hypothesis that IV...

Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation: The M&Ms Challenge.

IEEE transactions on medical imaging

Campello VM, Gkontra P, Izquierdo C, Martin-Isla C, Sojoudi A, Full PM, Maier-Hein K, Zhang Y, He Z, Ma J, Parreno M, Albiol A, Kong F, Shadden SC, Acero JC, Sundaresan V, Saber M, Elattar M, Li H, Menze B, Khader F, Haarburger C, Scannell CM, Veta M, Carscadden A, Punithakumar K, Liu X, Tsaftaris SA, Huang X, Yang X, Li L, Zhuang X, Vilades D, Descalzo ML, Guala A, Mura L, Friedrich MG, Garg R, Lebel J, Henriques F, Karakas M, Cavus E, Petersen SE, Escalera S, Segui S, Rodriguez-Palomares JF, Lekadir K.
PMID: 34138702
IEEE Trans Med Imaging. 2021 Dec;40(12):3543-3554. doi: 10.1109/TMI.2021.3090082. Epub 2021 Nov 30.

The emergence of deep learning has considerably advanced the state-of-the-art in cardiac magnetic resonance (CMR) segmentation. Many techniques have been proposed over the last few years, bringing the accuracy of automated segmentation close to human performance. However, these models...

Recovery opioid overdose team (ROOT) pilot program evaluation: A community-wide post-overdose response strategy.

Substance abuse

Dahlem CHG, Scalera M, Anderson G, Tasker M, Ploutz-Snyder R, McCabe SE, Boyd CJ.
PMID: 33284095
Subst Abus. 2021;42(4):423-427. doi: 10.1080/08897077.2020.1847239. Epub 2020 Dec 07.

No abstract available.

Pre-existing Hemagglutinin Stalk Antibodies Correlate with Protection of Lower Respiratory Symptoms in Flu-Infected Transplant Patients.

Cell reports. Medicine

Aydillo T, Escalera A, Strohmeier S, Aslam S, Sanchez-Cespedes J, Ayllon J, Roca-Oporto C, Perez-Romero P, Montejo M, Gavalda J, Munoz P, Lopez-Medrano F, Carratala J, Krammer F, García-Sastre A, Cordero E.
PMID: 33294855
Cell Rep Med. 2020 Nov 03;1(8):100130. doi: 10.1016/j.xcrm.2020.100130. eCollection 2020 Nov 17.

Hemagglutination-inhibitory antibodies are usually highly strain specific with little effect on infection with drifted or shifted strains. The significance of broadly cross-reactive non-HAI anti-influenza antibodies against conserved domains of virus glycoproteins, such as the hemagglutinin (HA) stalk, is of...

Action Recognition Using Single-Pixel Time-of-Flight Detection.

Entropy (Basel, Switzerland)

Ofodile I, Helmi A, Clapés A, Avots E, Peensoo KM, Valdma SM, Valdmann A, Valtna-Lukner H, Omelkov S, Escalera S, Ozcinar C, Anbarjafari G.
PMID: 33267128
Entropy (Basel). 2019 Apr 18;21(4). doi: 10.3390/e21040414.

Action recognition is a challenging task that plays an important role in many robotic systems, which highly depend on visual input feeds. However, due to privacy concerns, it is important to find a method which can recognise actions without...

Observed and Expected Survival in Men and Women After Suffering a STEMI.

Journal of clinical medicine

Pascual I, Hernandez-Vaquero D, Almendarez M, Lorca R, Escalera A, Díaz R, Alperi A, Carnero M, Silva J, Morís C, Avanzas P.
PMID: 32325887
J Clin Med. 2020 Apr 19;9(4). doi: 10.3390/jcm9041174.

INTRODUCTION: Mortality caused by ST elevation myocardial infarction (STEMI) has declined because of greater use of primary percutaneous coronary intervention (PCI). It is unknown if patients >75 have similar survival as peers. We aim to know it stratifying by...

Interrelations of Oxygen Evolution and Iridium Dissolution Mechanisms.

Angewandte Chemie (International ed. in English)

Lončar A, Escalera D, Cherevko S, Hodnik N.
PMID: 34942052
Angew Chem Int Ed Engl. 2021 Dec 23; doi: 10.1002/anie.202114437. Epub 2021 Dec 23.

Widespread utilization of proton exchange membrane (PEM) electrolyzers is currently still uncertain, as it inevitably relies on the use of highly scarce iridium as the only viable catalyst for oxygen evolution reaction (OER), which is known to present the...

Subchondral Bone Length in Knee Osteoarthritis: A Deep Learning-Derived Imaging Measure and Its Association With Radiographic and Clinical Outcomes.

Arthritis & rheumatology (Hoboken, N.J.)

Chang GH, Park LK, Le NA, Jhun RS, Surendran T, Lai J, Seo H, Promchotichai N, Yoon G, Scalera J, Capellini TD, Felson DT, Kolachalama VB.
PMID: 33973737
Arthritis Rheumatol. 2021 Dec;73(12):2240-2248. doi: 10.1002/art.41808. Epub 2021 Oct 29.

OBJECTIVE: To develop a bone shape measure that reflects the extent of cartilage loss and bone flattening in knee osteoarthritis (OA) and test it against estimates of disease severity.METHODS: A fast region-based convolutional neural network was trained to crop...

Rationale and design of the pragmatic clinical trial tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion (REBOOT).

European heart journal. Cardiovascular pharmacotherapy

Rossello X, Raposeiras-Roubin S, Latini R, Dominguez-Rodriguez A, Barrabés JA, Sánchez PL, Anguita M, Fernández-Vázquez F, Pascual-Figal D, De la Torre Hernandez JM, Ferraro S, Vetrano A, Pérez-Rivera JA, Prada-Delgado O, Escalera N, Staszewsky L, Pizarro G, Agüero J, Pocock S, Ottani F, Fuster V, Ibáñez B.
PMID: 34351426
Eur Heart J Cardiovasc Pharmacother. 2021 Aug 05; doi: 10.1093/ehjcvp/pvab060. Epub 2021 Aug 05.

BACKGROUND: There is a lack of evidence regarding the benefits of β-blocker treatment after invasively managed acute myocardial infarction (MI) without reduced left ventricular ejection fraction (LVEF).METHODS AND RESULTS: TREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fraction...

Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice.

Frontiers in pharmacology

Ardaiz N, Gomar C, Vasquez M, Tenesaca S, Fernandez-Sendin M, Di Trani CA, Belsué V, Escalada J, Werner U, Tennagels N, Berraondo P.
PMID: 33679386
Front Pharmacol. 2021 Feb 19;11:591293. doi: 10.3389/fphar.2020.591293. eCollection 2020.

No abstract available.

Showing 13 to 24 of 126 entries