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The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity.

International journal of biological macromolecules

Abu-Hussien M, Viswanathan GK, Simhaev L, Paul A, Engel H, Gazit E, Segal D.
PMID: 34998884
Int J Biol Macromol. 2022 Jan 05; doi: 10.1016/j.ijbiomac.2021.12.192. Epub 2022 Jan 05.

Human γD-crystallin protein is abundant in the lens and is essential for preserving lens transparency. With age the protein may lose its native structure resulting in the formation of cataract. We recently reported an aggregative peptide,

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Abu-Hussien M, Viswanathan GK, Simhaev L, et al. The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity. Int J Biol Macromol. 2022;doi: 10.1016/j.ijbiomac.2021.12.192.
Abu-Hussien, M., Viswanathan, G. K., Simhaev, L., Paul, A., Engel, H., Gazit, E., & Segal, D. (2022). The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity. International journal of biological macromolecules, . https://doi.org/10.1016/j.ijbiomac.2021.12.192
Abu-Hussien, Malak, et al. "The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity." International journal of biological macromolecules vol. (2022). doi: https://doi.org/10.1016/j.ijbiomac.2021.12.192
Abu-Hussien M, Viswanathan GK, Simhaev L, Paul A, Engel H, Gazit E, Segal D. The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity. Int J Biol Macromol. 2022 Jan 05; doi: 10.1016/j.ijbiomac.2021.12.192. Epub 2022 Jan 05. PMID: 34998884.
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Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy.

Journal of inflammation research

Engel T, Smith J, Alves M.
PMID: 34305404
J Inflamm Res. 2021 Jul 18;14:3367-3392. doi: 10.2147/JIR.S287740. eCollection 2021.

Treatment of epilepsy remains a clinical challenge, with >30% of patients not responding to current antiseizure drugs (ASDs). Moreover, currently available ASDs are merely symptomatic without altering significantly the progression of the disease. Inflammation is increasingly recognized as playing...

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Engel T, Smith J, Alves M. Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy. J Inflamm Res. 2021;14:3367-3392doi: 10.2147/JIR.S287740.
Engel, T., Smith, J., & Alves, M. (2021). Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy. Journal of inflammation research, 143367-3392. https://doi.org/10.2147/JIR.S287740
Engel, Tobias, et al. "Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy." Journal of inflammation research vol. 14 (2021): 3367-3392. doi: https://doi.org/10.2147/JIR.S287740
Engel T, Smith J, Alves M. Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy. J Inflamm Res. 2021 Jul 18;14:3367-3392. doi: 10.2147/JIR.S287740. eCollection 2021. PMID: 34305404; PMCID: PMC8298823.
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Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis.

Proceedings of the National Academy of Sciences of the United States of America

Bufe A, García Del Arco A, Hennecke M, de Jaime-Soguero A, Ostermaier M, Lin YC, Ciprianidis A, Hattemer J, Engel U, Beli P, Bastians H, Acebrón SP.
PMID: 34417301
Proc Natl Acad Sci U S A. 2021 Aug 24;118(34). doi: 10.1073/pnas.2108145118.

Canonical Wnt signaling plays critical roles in development and tissue renewal by regulating β-catenin target genes. Recent evidence showed that β-catenin-independent Wnt signaling is also required for faithful execution of mitosis. However, the targets and specific functions of mitotic...

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Bufe A, García Del Arco A, Hennecke M, et al. Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis. Proc Natl Acad Sci U S A. 2021;118(34)doi: 10.1073/pnas.2108145118.
Bufe, A., García Del Arco, A., Hennecke, M., de Jaime-Soguero, A., Ostermaier, M., Lin, Y. C., Ciprianidis, A., Hattemer, J., Engel, U., Beli, P., Bastians, H., & Acebrón, S. P. (2021). Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis. Proceedings of the National Academy of Sciences of the United States of America, 118(34), . https://doi.org/10.1073/pnas.2108145118
Bufe, Anja, et al. "Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis." Proceedings of the National Academy of Sciences of the United States of America vol. 118,34 (2021). doi: https://doi.org/10.1073/pnas.2108145118
Bufe A, García Del Arco A, Hennecke M, de Jaime-Soguero A, Ostermaier M, Lin YC, Ciprianidis A, Hattemer J, Engel U, Beli P, Bastians H, Acebrón SP. Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34). doi: 10.1073/pnas.2108145118. PMID: 34417301; PMCID: PMC8403935.
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Gamow-Teller Strength in ^{48}Ca and ^{78}Ni with the Charge-Exchange Subtracted Second Random-Phase Approximation.

Physical review letters

Gambacurta D, Grasso M, Engel J.
PMID: 33274967
Phys Rev Lett. 2020 Nov 20;125(21):212501. doi: 10.1103/PhysRevLett.125.212501.

We develop a fully self-consistent subtracted second random-phase approximation for charge-exchange processes with Skyrme energy-density functionals. As a first application, we study Gamow-Teller excitations in the doubly magic nucleus ^{48}Ca, the lightest double-β emitter that could be used in...

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Gambacurta D, Grasso M, Engel J. Gamow-Teller Strength in ^{48}Ca and ^{78}Ni with the Charge-Exchange Subtracted Second Random-Phase Approximation. Phys Rev Lett. 2020;125(21):212501doi: 10.1103/PhysRevLett.125.212501.
Gambacurta, D., Grasso, M., & Engel, J. (2020). Gamow-Teller Strength in ^{48}Ca and ^{78}Ni with the Charge-Exchange Subtracted Second Random-Phase Approximation. Physical review letters, 125(21), 212501. https://doi.org/10.1103/PhysRevLett.125.212501
Gambacurta, D, et al. "Gamow-Teller Strength in ^{48}Ca and ^{78}Ni with the Charge-Exchange Subtracted Second Random-Phase Approximation." Physical review letters vol. 125,21 (2020): 212501. doi: https://doi.org/10.1103/PhysRevLett.125.212501
Gambacurta D, Grasso M, Engel J. Gamow-Teller Strength in ^{48}Ca and ^{78}Ni with the Charge-Exchange Subtracted Second Random-Phase Approximation. Phys Rev Lett. 2020 Nov 20;125(21):212501. doi: 10.1103/PhysRevLett.125.212501. PMID: 33274967.
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A conspicuous reduced plasma creatinine: the first presenting sign of Waldenstrom macroglobulinemia.

Clinical chemistry and laboratory medicine

Potze W, Vos MJ, Engel H, Doornebal J.
PMID: 34480845
Clin Chem Lab Med. 2021 Sep 06;60(1):e21-e24. doi: 10.1515/cclm-2021-0742. Print 2022 Jan 26.

No abstract available.

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Potze W, Vos MJ, Engel H, et al. A conspicuous reduced plasma creatinine: the first presenting sign of Waldenstrom macroglobulinemia. Clin Chem Lab Med. 2021;60(1):e21-e24doi: 10.1515/cclm-2021-0742.
Potze, W., Vos, M. J., Engel, H., & Doornebal, J. (2022). A conspicuous reduced plasma creatinine: the first presenting sign of Waldenstrom macroglobulinemia. Clinical chemistry and laboratory medicine, 60(1), e21-e24. https://doi.org/10.1515/cclm-2021-0742
Potze, Wilma, et al. "A conspicuous reduced plasma creatinine: the first presenting sign of Waldenstrom macroglobulinemia." Clinical chemistry and laboratory medicine vol. 60,1 (2022): e21-e24. doi: https://doi.org/10.1515/cclm-2021-0742
Potze W, Vos MJ, Engel H, Doornebal J. A conspicuous reduced plasma creatinine: the first presenting sign of Waldenstrom macroglobulinemia. Clin Chem Lab Med. 2021 Sep 06;60(1):e21-e24. doi: 10.1515/cclm-2021-0742. Print 2022 Jan 26. PMID: 34480845.
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Editorial: Scanning Probe Microscopies and Related Methods in Biology.

Frontiers in molecular biosciences

Engel A, Alsteens D, Müller DJ.
PMID: 33869289
Front Mol Biosci. 2021 Mar 29;8:657939. doi: 10.3389/fmolb.2021.657939. eCollection 2021.

No abstract available.

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Engel A, Alsteens D, Müller DJ. Editorial: Scanning Probe Microscopies and Related Methods in Biology. Front Mol Biosci. 2021;8:657939doi: 10.3389/fmolb.2021.657939.
Engel, A., Alsteens, D., & Müller, D. J. (2021). Editorial: Scanning Probe Microscopies and Related Methods in Biology. Frontiers in molecular biosciences, 8657939. https://doi.org/10.3389/fmolb.2021.657939
Engel, Andreas, et al. "Editorial: Scanning Probe Microscopies and Related Methods in Biology." Frontiers in molecular biosciences vol. 8 (2021): 657939. doi: https://doi.org/10.3389/fmolb.2021.657939
Engel A, Alsteens D, Müller DJ. Editorial: Scanning Probe Microscopies and Related Methods in Biology. Front Mol Biosci. 2021 Mar 29;8:657939. doi: 10.3389/fmolb.2021.657939. eCollection 2021. PMID: 33869289; PMCID: PMC8044836.
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Effect of Remote Cardiac Monitoring System Design on Response Time to Critical Arrhythmias.

Simulation in healthcare : journal of the Society for Simulation in Healthcare

Segall N, Joines JA, Baldwin RD, Bresch D, Coggins LG, Janzen S, Engel JR, Wright MC.
PMID: 34506366
Simul Healthc. 2021 Sep 09; doi: 10.1097/SIH.0000000000000610. Epub 2021 Sep 09.

INTRODUCTION: In many hospitals across the country, electrocardiograms of multiple at-risk patients are monitored remotely by telemetry monitor watchers in a central location. However, there is limited evidence regarding best practices for designing these cardiac monitoring systems to ensure...

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Segall N, Joines JA, Baldwin RD, et al. Effect of Remote Cardiac Monitoring System Design on Response Time to Critical Arrhythmias. Simul Healthc. 2021;doi: 10.1097/SIH.0000000000000610.
Segall, N., Joines, J. A., Baldwin, R. D., Bresch, D., Coggins, L. G., Janzen, S., Engel, J. R., & Wright, M. C. (2021). Effect of Remote Cardiac Monitoring System Design on Response Time to Critical Arrhythmias. Simulation in healthcare : journal of the Society for Simulation in Healthcare, . https://doi.org/10.1097/SIH.0000000000000610
Segall, Noa, et al. "Effect of Remote Cardiac Monitoring System Design on Response Time to Critical Arrhythmias." Simulation in healthcare : journal of the Society for Simulation in Healthcare vol. (2021). doi: https://doi.org/10.1097/SIH.0000000000000610
Segall N, Joines JA, Baldwin RD, Bresch D, Coggins LG, Janzen S, Engel JR, Wright MC. Effect of Remote Cardiac Monitoring System Design on Response Time to Critical Arrhythmias. Simul Healthc. 2021 Sep 09; doi: 10.1097/SIH.0000000000000610. Epub 2021 Sep 09. PMID: 34506366.
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Psychological and pharmacological interventions for depression in patients with coronary artery disease.

The Cochrane database of systematic reviews

Tully PJ, Ang SY, Lee EJ, Bendig E, Bauereiß N, Bengel J, Baumeister H.
PMID: 34910821
Cochrane Database Syst Rev. 2021 Dec 15;12:CD008012. doi: 10.1002/14651858.CD008012.pub4.

BACKGROUND: Depression occurs frequently in individuals with coronary artery disease (CAD) and is associated with a poor prognosis.OBJECTIVES: To determine the effects of psychological and pharmacological interventions for depression in CAD patients with comorbid depression.SEARCH METHODS: We searched the...

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Tully PJ, Ang SY, Lee EJ, et al. Psychological and pharmacological interventions for depression in patients with coronary artery disease. Cochrane Database Syst Rev. 2021;12:CD008012doi: 10.1002/14651858.CD008012.pub4.
Tully, P. J., Ang, S. Y., Lee, E. J., Bendig, E., Bauereiß, N., Bengel, J., & Baumeister, H. (2021). Psychological and pharmacological interventions for depression in patients with coronary artery disease. The Cochrane database of systematic reviews, 12CD008012. https://doi.org/10.1002/14651858.CD008012.pub4
Tully, Phillip J, et al. "Psychological and pharmacological interventions for depression in patients with coronary artery disease." The Cochrane database of systematic reviews vol. 12 (2021): CD008012. doi: https://doi.org/10.1002/14651858.CD008012.pub4
Tully PJ, Ang SY, Lee EJ, Bendig E, Bauereiß N, Bengel J, Baumeister H. Psychological and pharmacological interventions for depression in patients with coronary artery disease. Cochrane Database Syst Rev. 2021 Dec 15;12:CD008012. doi: 10.1002/14651858.CD008012.pub4. PMID: 34910821; PMCID: PMC8673695.
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Macromolecular Ligand Engineering for Programmable Nanoprism Assembly.

Journal of the American Chemical Society

Liu Y, Klement M, Wang Y, Zhong Y, Zhu B, Chen J, Engel M, Ye X.
PMID: 34549954
J Am Chem Soc. 2021 Oct 06;143(39):16163-16172. doi: 10.1021/jacs.1c07281. Epub 2021 Sep 22.

Ligands play a central role for the energetics and kinetics of nanocrystal assembly. Yet, the precise and simultaneous manipulation of ligands to dictate assembly outcome has proven difficult. Here, we present macromolecular ligand-engineering strategies to control, characterize, and model...

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Liu Y, Klement M, Wang Y, et al. Macromolecular Ligand Engineering for Programmable Nanoprism Assembly. J Am Chem Soc. 2021;143(39):16163-16172doi: 10.1021/jacs.1c07281.
Liu, Y., Klement, M., Wang, Y., Zhong, Y., Zhu, B., Chen, J., Engel, M., & Ye, X. (2021). Macromolecular Ligand Engineering for Programmable Nanoprism Assembly. Journal of the American Chemical Society, 143(39), 16163-16172. https://doi.org/10.1021/jacs.1c07281
Liu, Yang, et al. "Macromolecular Ligand Engineering for Programmable Nanoprism Assembly." Journal of the American Chemical Society vol. 143,39 (2021): 16163-16172. doi: https://doi.org/10.1021/jacs.1c07281
Liu Y, Klement M, Wang Y, Zhong Y, Zhu B, Chen J, Engel M, Ye X. Macromolecular Ligand Engineering for Programmable Nanoprism Assembly. J Am Chem Soc. 2021 Oct 06;143(39):16163-16172. doi: 10.1021/jacs.1c07281. Epub 2021 Sep 22. PMID: 34549954.
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Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.

Journal of hepatology

Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD.
PMID: 34453962
J Hepatol. 2021 Dec;75(6):1420-1433. doi: 10.1016/j.jhep.2021.08.011. Epub 2021 Aug 25.

BACKGROUND & AIMS: Therapeutic targeting of injuries that require transient restoration of proteins by mRNA delivery is an attractive approach that, until recently, has remained poorly explored. In this study, we examined the therapeutic utility of mRNA delivery for...

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Yang T, Poenisch M, Khanal R, et al. Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. J Hepatol. 2021;75(6):1420-1433doi: 10.1016/j.jhep.2021.08.011.
Yang, T., Poenisch, M., Khanal, R., Hu, Q., Dai, Z., Li, R., Song, G., Yuan, Q., Yao, Q., Shen, X., Taubert, R., Engel, B., Jaeckel, E., Vogel, A., Falk, C. S., Schambach, A., Gerovska, D., Araúzo-Bravo, M. J., Vondran, F. W. R., Cantz, T., Horscroft, N., Balakrishnan, A., Chevessier, F., Ott, M., & Sharma, A. D. (2021). Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. Journal of hepatology, 75(6), 1420-1433. https://doi.org/10.1016/j.jhep.2021.08.011
Yang, Taihua, et al. "Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model." Journal of hepatology vol. 75,6 (2021): 1420-1433. doi: https://doi.org/10.1016/j.jhep.2021.08.011
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD. Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. J Hepatol. 2021 Dec;75(6):1420-1433. doi: 10.1016/j.jhep.2021.08.011. Epub 2021 Aug 25. PMID: 34453962.
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A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis.

Journal of the Korean Association of Oral and Maxillofacial Surgeons

Ristow O, Hürtgen L, Moratin J, Smielowski M, Freudlsperger C, Engel M, Hoffmann J, Rückschloß T.
PMID: 33911042
J Korean Assoc Oral Maxillofac Surg. 2021 Apr 30;47(2):99-111. doi: 10.5125/jkaoms.2021.47.2.99.

OBJECTIVES: It is unclear whether the extent of intraoral mucosa defects in patients with medication-related osteonecrosis of the jaw indicates disease severity. Therefore, this study investigated whether mucosal lesions correlate with the true extent of osseous defects in stage...

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Ristow O, Hürtgen L, Moratin J, et al. A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis. J Korean Assoc Oral Maxillofac Surg. 2021;47(2):99-111doi: 10.5125/jkaoms.2021.47.2.99.
Ristow, O., Hürtgen, L., Moratin, J., Smielowski, M., Freudlsperger, C., Engel, M., Hoffmann, J., & Rückschloß, T. (2021). A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 47(2), 99-111. https://doi.org/10.5125/jkaoms.2021.47.2.99
Ristow, Oliver, et al. "A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis." Journal of the Korean Association of Oral and Maxillofacial Surgeons vol. 47,2 (2021): 99-111. doi: https://doi.org/10.5125/jkaoms.2021.47.2.99
Ristow O, Hürtgen L, Moratin J, Smielowski M, Freudlsperger C, Engel M, Hoffmann J, Rückschloß T. A critical assessment of the medication-related osteonecrosis of the jaw classification in stage I patients: a retrospective analysis. J Korean Assoc Oral Maxillofac Surg. 2021 Apr 30;47(2):99-111. doi: 10.5125/jkaoms.2021.47.2.99. PMID: 33911042; PMCID: PMC8084747.
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Promoting adolescent health through integrated human papillomavirus vaccination programs: The experience of Togo.

Vaccine

Engel D, Afeli ADJ, Morgan C, Zeck W, Ross DA, Vyankandondera J, Bloem P, Adjeoda KR.
PMID: 34844819
Vaccine. 2021 Nov 26; doi: 10.1016/j.vaccine.2021.11.021. Epub 2021 Nov 26.

The introduction of the Human papillomavirus (HPV) vaccine has shown potential to not only prevent cervical cancer but also drive adolescents' access to other health care services, even in low-income countries. Few studies have been conducted to date to...

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Engel D, Afeli ADJ, Morgan C, et al. Promoting adolescent health through integrated human papillomavirus vaccination programs: The experience of Togo. Vaccine. 2021;doi: 10.1016/j.vaccine.2021.11.021.
Engel, D., Afeli, A. D. J., Morgan, C., Zeck, W., Ross, D. A., Vyankandondera, J., Bloem, P., & Adjeoda, K. R. (2021). Promoting adolescent health through integrated human papillomavirus vaccination programs: The experience of Togo. Vaccine, . https://doi.org/10.1016/j.vaccine.2021.11.021
Engel, Danielle, et al. "Promoting adolescent health through integrated human papillomavirus vaccination programs: The experience of Togo." Vaccine vol. (2021). doi: https://doi.org/10.1016/j.vaccine.2021.11.021
Engel D, Afeli ADJ, Morgan C, Zeck W, Ross DA, Vyankandondera J, Bloem P, Adjeoda KR. Promoting adolescent health through integrated human papillomavirus vaccination programs: The experience of Togo. Vaccine. 2021 Nov 26; doi: 10.1016/j.vaccine.2021.11.021. Epub 2021 Nov 26. PMID: 34844819.
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Showing 1417 to 1428 of 1433 entries