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Showing 25 to 36 of 320 entries
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Oral vaccination protects against SARS-CoV-2 in a Syrian hamster challenge model.

The Journal of infectious diseases

Johnson S, Martinez CI, Tedjakusuma SN, Peinovich N, Dora EG, Birch SM, Kajon AE, Werts AD, Tucker SN.
PMID: 34758086
J Infect Dis. 2021 Nov 10; doi: 10.1093/infdis/jiab561. Epub 2021 Nov 10.

Vaccines that are shelf stable and easy to administer are crucial to improve vaccine access and reduce SARS-CoV-2 transmission around the world. Here we demonstrate that an oral, adenovirus-based vaccine candidate protects against SARS-CoV-2 in a Syrian hamster challenge...

Concept Map Assessment Reveals Short-Term Community-Engaged Fieldwork Enhances Sustainability Knowledge.

CBE life sciences education

Pruett JL, Weigel EG.
PMID: 32870087
CBE Life Sci Educ. 2020 Sep;19(3):ar38. doi: 10.1187/cbe.20-02-0031.

Today's rapidly changing world calls for sustainability-minded scientists who are prepared to solve complex, interconnected problems. Service learning is a pedagogical approach that allows students to engage with the needs of the community by integrating academic work with complex...

Care Managers and Role Ambiguity: The Challenges of Supporting the Mental Health Needs of Patients with Chronic Conditions.

Computer supported cooperative work : CSCW : an international journal

Lattie EG, Burgess E, Mohr DC, Reddy M.
PMID: 34149187
Comput Support Coop Work. 2021 Feb;30(1):1-34. doi: 10.1007/s10606-020-09391-z. Epub 2021 Jan 18.

As U.S. healthcare organizations transition to value-based healthcare, they are increasingly focusing on supporting patients who have difficulties managing chronic care, including mental health, through the growing role of care managers (CMs). CMs communicate with patients, provide access to...

Identifying and correcting spatial bias in opportunistic citizen science data for wild ungulates in Norway.

Ecology and evolution

Cretois B, Simmonds EG, Linnell JDC, van Moorter B, Rolandsen CM, Solberg EJ, Strand O, Gundersen V, Roer O, Rød JK.
PMID: 34765170
Ecol Evol. 2021 Oct 05;11(21):15191-15204. doi: 10.1002/ece3.8200. eCollection 2021 Nov.

Many publications make use of opportunistic data, such as citizen science observation data, to infer large-scale properties of species' distributions. However, the few publications that use opportunistic citizen science data to study animal ecology at a habitat level do...

Influenza-Like Illness Among Personnel Responding to U.S. Quarantine of Cruise Ship Passengers Exposed to SARS-CoV-2.

Journal of occupational and environmental medicine

Harvey RR, Nett RJ, McNamara K, McClung RP, Pieracci EG, Mayer O, Labar KA, Xu K, Facey J, Honein MA.
PMID: 34310544
J Occup Environ Med. 2022 Jan 01;64(1):58-63. doi: 10.1097/JOM.0000000000002335.

OBJECTIVES: Before community transmission of COVID-19 was recognized in the United States, cruise ship passengers with high risk for exposure to SARS-CoV-2 were repatriated and quarantined. We describe cases of influenza-like illness (ILI) among responders.METHODS: We reviewed situation reports...

Bayesian Network Analysis reveals resilience of the jellyfish Aurelia aurita to an Irish Sea regime shift.

Scientific reports

Mitchell EG, Wallace MI, Smith VA, Wiesenthal AA, Brierley AS.
PMID: 33580138
Sci Rep. 2021 Feb 12;11(1):3707. doi: 10.1038/s41598-021-82825-w.

Robust time-series of direct observations of jellyfish abundance are not available for many ecosystems, leaving it difficult to determine changes in jellyfish abundance, the possible causes (e.g. climate change) or the consequences (e.g. trophic cascades). We sought an indirect...

A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer.

Cancer discovery

Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM.
PMID: 33608386
Cancer Discov. 2021 Jul;11(7):1754-1773. doi: 10.1158/2159-8290.CD-20-1325. Epub 2021 Feb 19.

Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis is a multistep process, but the importance and specific roles of many of these genes during tumor initiation, growth, and progression remain unknown. Here we use...

Donation after circulatory death donors in lung transplantation.

Journal of thoracic disease

Egan TM, Haithcock BE, Lobo J, Mody G, Love RB, Requard JJ, Espey J, Ali MH.
PMID: 34992833
J Thorac Dis. 2021 Nov;13(11):6536-6549. doi: 10.21037/jtd-2021-13.

Transplantation of any organ into a recipient requires a donor. Lung transplant has a long history of an inadequate number of suitable donors to meet demand, leading to deaths on the waiting list annually since national data was collected,...

A review of pruritus in pregnancy.

Obstetric medicine

Rudder M, Lefkowitz EG, Ruhama T, Firoz E.
PMID: 34880932
Obstet Med. 2021 Dec;14(4):204-210. doi: 10.1177/1753495X20985366. Epub 2021 Jan 21.

Pruritus is a common dermatologic complaint during pregnancy. Pruritus is reported by 23-38% of women during pregnancy, and 2% report severe pruritus. In addition to interfering with sleep and reducing overall quality of life during pregnancy, pruritus may be...

Role of Immune and Autoimmune Dysfunction in Schizophrenia.

Handbook of behavioral neuroscience

Severance EG, Yolken RH.
PMID: 33456427
Handb Behav Neurosci. 2016;23:501-516. doi: 10.1016/B978-0-12-800981-9.00029-8. Epub 2015 Nov 10.

In this chapter, we review data in support of the concept that immune system dysregulation is the most plausible explanation that reconciles gene by environmental interactions in schizophrenia. Early investigations of this topic demonstrated aspects of aberrant activation of...

The Menstrual Cycle Modulates Whole-Brain Turbulent Dynamics.

Frontiers in neuroscience

De Filippi E, Uribe C, Avila-Varela DS, Martínez-Molina N, Gashaj V, Pritschet L, Santander T, Jacobs EG, Kringelbach ML, Sanz Perl Y, Deco G, Escrichs A.
PMID: 34955718
Front Neurosci. 2021 Dec 09;15:753820. doi: 10.3389/fnins.2021.753820. eCollection 2021.

Brain dynamics have recently been shown to be modulated by rhythmic changes in female sex hormone concentrations across an entire menstrual cycle. However, many questions remain regarding the specific differences in information processing across spacetime between the two main...

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep.

JCI insight

Ferguson CM, Godinho BM, Alterman JF, Coles AH, Hassler M, Echeverria D, Gilbert JW, Knox EG, Caiazzi J, Haraszti RA, King RM, Taghian T, Puri A, Moser RP, Gounis MJ, Aronin N, Gray-Edwards H, Khvorova A.
PMID: 34935646
JCI Insight. 2021 Dec 22;6(24). doi: 10.1172/jci.insight.152203.

siRNAs comprise a class of drugs that can be programmed to silence any target gene. Chemical engineering efforts resulted in development of divalent siRNAs (di-siRNAs), which support robust and long-term efficacy in rodent and nonhuman primate brains upon direct...

Showing 25 to 36 of 320 entries