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Showing 25 to 36 of 221 entries
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Assessment of operating room team members' ability to identify other team members in the operating room, a quality improvement exercise.

Irish journal of medical science

Scott E, Lindow SW, Duffy CC.
PMID: 33550487
Ir J Med Sci. 2021 Feb 07; doi: 10.1007/s11845-021-02521-6. Epub 2021 Feb 07.

No abstract available.

Errata.

The bone & joint journal

You D, Sepehri A, Kooner S, Krzyzaniak H, Johal H, Duffy P, Schneider P, Powell J.
PMID: 32862692
Bone Joint J. 2020 Sep;102(9):1268. doi: 10.1302/0301-620X.102B9.BJJ-2020-00011.

No abstract available.

Elucidation of the Host Bronchial Lymph Node miRNA Transcriptome Response to Bovine Respiratory Syncytial Virus.

Frontiers in genetics

Johnston D, Earley B, McCabe MS, Kim J, Taylor JF, Lemon K, McMenamy M, Duffy C, Cosby SL, Waters SM.
PMID: 33968129
Front Genet. 2021 Apr 22;12:633125. doi: 10.3389/fgene.2021.633125. eCollection 2021.

Bovine respiratory disease (BRD) causes substantial morbidity and mortality, affecting cattle of all ages. One of the main causes of BRD is an initial inflammatory response to bovine respiratory syncytial virus (BRSV). MicroRNAs are novel and emerging non-coding small...

An actuatable soft reservoir modulates host foreign body response.

Science robotics

Dolan EB, Varela CE, Mendez K, Whyte W, Levey RE, Robinson ST, Maye E, O'Dwyer J, Beatty R, Rothman A, Fan Y, Hochstein J, Rothenbucher SE, Wylie R, Starr JR, Monaghan M, Dockery P, Duffy GP, Roche ET.
PMID: 33137787
Sci Robot. 2019 Aug 28;4(33). doi: 10.1126/scirobotics.aax7043.

The performance of indwelling medical devices that depend on an interface with soft tissue is plagued by complex, unpredictable foreign body responses. Such devices-including breast implants, biosensors, and drug delivery devices-are often subject to a collection of biological host...

Repeated hippocampal seizures lead to brain-wide reorganization of circuits and seizure propagation pathways.

Neuron

Choy M, Dadgar-Kiani E, Cron GO, Duffy BA, Schmid F, Edelman BJ, Asaad M, Chan RW, Vahdat S, Lee JH.
PMID: 34706219
Neuron. 2021 Oct 23; doi: 10.1016/j.neuron.2021.10.010. Epub 2021 Oct 23.

Repeated seizure activity can lead to long-term changes in seizure dynamics and behavior. However, resulting changes in brain-wide dynamics remain poorly understood. This is due partly to technical challenges in precise seizure control and in vivo whole-brain mapping of...

The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model.

Tissue engineering. Part C, Methods

Beatty R, Lu CE, Marzi J, Levey RE, Carvajal Berrio D, Lattanzi G, Wylie R, O'Connor R, Wallace E, Ghersi G, Salamone M, Dolan EB, Layland SL, Schenke-Layland K, Duffy GP.
PMID: 34541880
Tissue Eng Part C Methods. 2021 Oct;27(10):515-528. doi: 10.1089/ten.TEC.2021.0163.

Advancements in type 1 diabetes mellitus treatments have vastly improved in recent years. The move toward a bioartificial pancreas and other fully implantable systems could help restore patient's glycemic control. However, the long-term success of implantable medical devices is...

Small Non-coding RNA Expression Following Respiratory Syncytial Virus or Measles Virus Infection of Neuronal Cells.

Frontiers in microbiology

Bakre AA, Duffy C, Abdullah H, Cosby SL, Tripp RA.
PMID: 34539595
Front Microbiol. 2021 Sep 03;12:671852. doi: 10.3389/fmicb.2021.671852. eCollection 2021.

Respiratory syncytial virus (RSV) or measles virus (MeV) infection modifies host responses through small non-coding RNA (sncRNA) expression. We show that RSV or MeV infection of neuronal cells induces sncRNAs including various microRNAs and transfer RNA fragments (tRFs). We...

Assessing red blood cell deformability from microscopy images using deep learning.

Lab on a chip

Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H.
PMID: 34874395
Lab Chip. 2021 Dec 21;22(1):26-39. doi: 10.1039/d1lc01006a.

Red blood cells (RBCs) must be highly deformable to transit through the microvasculature to deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural aging, or storage in blood bags can impede the proper function of...

SARS-CoV-2 seroassay performance and optimization in a population with high background reactivity in Mali.

The Journal of infectious diseases

Woodford J, Sagara I, Dicko A, Zeguime A, Doucoure M, Kwan J, Zaidi I, Doritchamou J, Snow-Smith M, Alani N, Renn J, Kosik I, Holly J, Yewdell J, Esposito D, Sadtler K, Duffy P.
PMID: 34612499
J Infect Dis. 2021 Oct 06; doi: 10.1093/infdis/jiab498. Epub 2021 Oct 06.

BACKGROUND: False positivity may hinder the utility of SARS-CoV-2 serological tests in sub-Saharan Africa.METHODS: From 312 Malian samples collected prior to 2020, we measured antibodies to the commonly tested SARS-CoV-2 antigens and four other betacoronaviruses by ELISA. In a...

Recent advances in immune-based approaches for the treatment of esophagogastric cancer.

Expert opinion on emerging drugs

Weadick CS, Duffy AG, Kelly RJ.
PMID: 34937483
Expert Opin Emerg Drugs. 2021 Dec 23; doi: 10.1080/14728214.2021.2020757. Epub 2021 Dec 23.

INTRODUCTION: The year 2021 will be remembered as a transformational year in the management of both esophageal and gastric cancers. Decades of failed clinical trials had seen limited therapeutic advances beyond refinement of the traditional combined modality approach. Targeted...

Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior.

Neurobiology of stress

Borodovitsyna O, Duffy BC, Pickering AE, Chandler DJ.
PMID: 33344735
Neurobiol Stress. 2020 Dec 05;13:100284. doi: 10.1016/j.ynstr.2020.100284. eCollection 2020 Nov.

The locus coeruleus (LC) is a critical node in the stress response, and its activation has been shown to promote hypervigilance and anxiety-like behavior. This noradrenergic nucleus has historically been considered homogeneous with highly divergent neurons that operate en...

SARS-CoV-2 seroassay optimization and performance in a population with high background reactivity in Mali.

medRxiv : the preprint server for health sciences

Sagara I, Woodford J, Dicko A, Zeguime A, Doucoure M, Kwan J, Zaidi I, Doritchamou J, Snow-Smith M, Alani N, Renn J, Kosik I, Holly J, Yewdell J, Esposito D, Sadtler K, Duffy P.
PMID: 33758883
medRxiv. 2021 Mar 12; doi: 10.1101/2021.03.08.21252784.

Serological tests are an indispensable tool to understand the epidemiology of the SARS-CoV-2 pandemic, particularly in areas where molecular diagnostics are limited. Poor assay performance may hinder the utility of these tests, including high rates of false-positivity previously reported...

Showing 25 to 36 of 221 entries