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Bioinformatic analysis and antiviral effect of Periplaneta americana defensins.

Virus research

Li Y, Cai J, Du C, Lin Y, Li S, Ma A, Qin Y.
PMID: 34785275
Virus Res. 2021 Nov 13;308:198627. doi: 10.1016/j.virusres.2021.198627. Epub 2021 Nov 13.

Due to the lack of an adaptive immune system, insects rely on innate immune mechanisms to fight against pathogenic infections. Two major innate immune pathways, Toll and IMD, orchestrate anti-pathogen responses by regulating the expression of antimicrobial peptide (AMP)...

Spectrum Sensing Method Based on Information Geometry and Deep Neural Network.

Entropy (Basel, Switzerland)

Du K, Wan P, Wang Y, Ai X, Chen H.
PMID: 33285869
Entropy (Basel). 2020 Jan 12;22(1). doi: 10.3390/e22010094.

Due to the scarcity of radio spectrum resources and the growing demand, the use of spectrum sensing technology to improve the utilization of spectrum resources has become a hot research topic. In order to improve the utilization of spectrum...

Explore the potential molecular mechanism of polycystic ovarian syndrome by protein-protein interaction network analysis.

Taiwanese journal of obstetrics & gynecology

Chen Q, Zheng B, Du S, Lin Y.
PMID: 34507653
Taiwan J Obstet Gynecol. 2021 Sep;60(5):807-815. doi: 10.1016/j.tjog.2021.07.005.

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders prevailing in reproductive age women, present in 3-15% population of women worldwide. Although there are many studies on PCOS, its underlying mechanism remains to be determined. The...

Circular Ribonucleic Acid circFTO Promotes Angiogenesis and Impairs Blood-Retinal Barrier .

Frontiers in molecular biosciences

Guo J, Xiao F, Ren W, Zhu Y, Du Q, Li Q, Li X.
PMID: 34422901
Front Mol Biosci. 2021 Aug 04;8:685466. doi: 10.3389/fmolb.2021.685466. eCollection 2021.

No abstract available.

Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact.

Geriatric nursing (New York, N.Y.)

Li Q, Zhang Q, Zhang S, Du M, Wang X, Hu S, Li L.
PMID: 34911018
Geriatr Nurs. 2021 Dec 12;43:175-181. doi: 10.1016/j.gerinurse.2021.11.019. Epub 2021 Dec 12.

This study aimed to evaluate the effects of frailty and social contact on cognitive decline among Chinese older patients with Alzheimer's disease (AD), and examine the mediating role of social contact between frailty and cognitive decline. A total of...

Multiomics Differences in Lung Squamous Cell Carcinoma Patients with High Radiosensitivity Index Compared with Those with Low Radiosensitivity Index.

Disease markers

Du Y, Yuan S, Zhuang X, Zhang Q, Qiao T.
PMID: 34504628
Dis Markers. 2021 Aug 30;2021:3766659. doi: 10.1155/2021/3766659. eCollection 2021.

OBJECTIVES: Radiosensitivity Index (RSI) can predict intrinsic radiotherapy sensitivity. We analyzed multiomics characteristics in lung squamous cell carcinoma between high and low RSI groups, which may help understand the underlying molecular mechanism of radiosensitivity and guide optional treatment for...

Immunosuppressive effect of Columbianadin on maturation, migration, allogenic T cell stimulation and phagocytosis capacity of TNF-α induced dendritic cells.

Journal of ethnopharmacology

Chen S, Bai Y, Wang Y, Liang C, Du K, Wang S, Li J, Chang YX.
PMID: 34919989
J Ethnopharmacol. 2021 Dec 14;285:114918. doi: 10.1016/j.jep.2021.114918. Epub 2021 Dec 14.

ETHNOPHARMACOLOGICAL RELEVANCE: Angelicae pubescentis radix (APR) has a long history in the treatment of rheumatoid arthritis (RA) in China. It has the effects of dispelling wind to eliminate dampness, removing arthralgia and stopping pain in the Chinese Pharmacopeia, but...

Circulating Tumor Cells (CTCs): A Unique Model of Cancer Metastases and Non-invasive Biomarkers of Therapeutic Response.

Frontiers in genetics

Liu J, Lian J, Chen Y, Zhao X, Du C, Xu Y, Hu H, Rao H, Hong X.
PMID: 34512735
Front Genet. 2021 Aug 25;12:734595. doi: 10.3389/fgene.2021.734595. eCollection 2021.

Late-stage cancer metastasis remains incurable in the clinic and is the major cause death in patients. Circulating tumor cells (CTCs) are thought to be metastatic precursors shed from the primary tumor or metastatic deposits and circulate in the blood....

Computational framework for generating large panoramic super-resolution images from localization microscopy.

Biomedical optics express

Du Y, Wang C, Zhang C, Guo L, Chen Y, Yan M, Feng Q, Shang M, Kuang W, Wang Z, Huang ZL.
PMID: 34513223
Biomed Opt Express. 2021 Jul 12;12(8):4759-4778. doi: 10.1364/BOE.433489. eCollection 2021 Aug 01.

Combining super-resolution localization microscopy with pathology creates new opportunities for biomedical researches. This combination requires a suitable image mosaic method for generating a panoramic image from many overlapping super-resolution images. However, current image mosaic methods are not suitable for...

Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes.

Stem cells international

Liu B, Wang D, Xiong T, Liu Y, Jing X, Du J, She Q.
PMID: 33897781
Stem Cells Int. 2021 Apr 09;2021:8859071. doi: 10.1155/2021/8859071. eCollection 2021.

BACKGROUND: The role of Notch signaling pathway in the differentiation of epicardial progenitor cells (EPCs) into adipocytes is unclear. The objective is to investigate the effects of Notch signaling on the differentiation of EPCs into adipocytes.METHODS: Frozen sections of...

Cost-effectiveness of prophylactic hysterectomy in first-degree female relatives with Lynch syndrome of patients diagnosed with colorectal cancer in the United States: a microsimulation study.

Cancer medicine

Alblas M, Peterse EFP, Du M, Zauber AG, Steyerberg EW, van Leeuwen N, Lansdorp-Vogelaar I.
PMID: 34510779
Cancer Med. 2021 Oct;10(19):6835-6844. doi: 10.1002/cam4.4080. Epub 2021 Sep 12.

BACKGROUND: To evaluate the cost-effectiveness of prophylactic hysterectomy (PH) in women with Lynch syndrome (LS).METHODS: We developed a microsimulation model incorporating the natural history for the development of hyperplasia with and without atypia into endometrial cancer (EC) based on...

Transanal Drainage Tube Use for Preventing Anastomotic Leakage After Laparoscopic Low Anterior Resection in Patients With Rectal Cancer: A Randomized Clinical Trial.

JAMA surgery

Zhao S, Zhang L, Gao F, Wu M, Zheng J, Bai L, Li F, Liu B, Pan Z, Liu J, Du K, Zhou X, Li C, Zhang A, Pu Z, Li Y, Feng B, Tong W.
PMID: 34613330
JAMA Surg. 2021 Dec 01;156(12):1151-1158. doi: 10.1001/jamasurg.2021.4568.

IMPORTANCE: Preventing anastomotic leakage (AL) is crucial for colorectal surgery. Some studies have suggested a positive role of transanal drainage tubes (TDTs) in AL prevention after low anterior resection, but this finding is controversial.OBJECTIVE: To assess the effect of...

Showing 3457 to 3468 of 22463 entries