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Showing 13 to 24 of 94 entries
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Department Chairs Weigh In: Environmental Health Education Is More Essential Than Ever.

American journal of public health

Turpin BJ, Baccarelli A, Dockery DW, Dolinoy DC, Levy JI, Liu Y, Perry MJ, Remais JV, Wills-Karp M.
PMID: 34936417
Am J Public Health. 2022 Jan;112(1):75-76. doi: 10.2105/AJPH.2021.306613.

No abstract available.

Whole genome sequencing and in vitro splice assays reveal genetic causes for inherited retinal diseases.

NPJ genomic medicine

Fadaie Z, Whelan L, Ben-Yosef T, Dockery A, Corradi Z, Gilissen C, Haer-Wigman L, Corominas J, Astuti GDN, de Rooij L, van den Born LI, Klaver CCW, Hoyng CB, Wynne N, Duignan ES, Kenna PF, Cremers FPM, Farrar GJ, Roosing S.
PMID: 34795310
NPJ Genom Med. 2021 Nov 18;6(1):97. doi: 10.1038/s41525-021-00261-1.

Inherited retinal diseases (IRDs) are a major cause of visual impairment. These clinically heterogeneous disorders are caused by pathogenic variants in more than 270 genes. As 30-40% of cases remain genetically unexplained following conventional genetic testing, we aimed to...

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population.

Aging cell

Riaz M, Huq A, Ryan J, Orchard SG, Tiller J, Lockery J, Woods RL, Wolfe R, Renton AE, Goate AM, Sebra R, Schadt E, Brodtmann A, Shah RC, Storey E, Murray AM, McNeil JJ, Lacaze P.
PMID: 34041846
Aging Cell. 2021 Jun;20(6):e13384. doi: 10.1111/acel.13384. Epub 2021 May 26.

Few studies have measured the effect of genetic factors on dementia and cognitive decline in healthy older individuals followed prospectively. We studied cumulative incidence of dementia and cognitive decline, stratified by APOE genotypes and polygenic risk score (PRS) tertiles,...

Mortality Benefits and Control Costs of Improving Air Quality in Mexico City: The Case of Heavy Duty Diesel Vehicles.

Risk analysis : an official publication of the Society for Risk Analysis

Evans JS, Rojas-Bracho L, Hammitt JK, Dockery DW.
PMID: 33368456
Risk Anal. 2021 Apr;41(4):661-677. doi: 10.1111/risa.13655. Epub 2020 Dec 24.

Diesel vehicles are significant contributors to air pollution in Mexico City. We estimate the costs and mortality benefits of retrofitting heavy-duty vehicles with particulate filters and oxidation catalysts. The feasibility and cost-effectiveness of controls differ by vehicle model-year and...

Effect of Aspirin on Activities of Daily Living Disability in Community-Dwelling Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences

Woods RL, Espinoza S, Thao LTP, Ernst ME, Ryan J, Wolfe R, Shah RC, Ward SA, Storey E, Nelson MR, Reid CM, Lockery JE, Orchard SG, Trevaks RE, Fitzgerald SM, Stocks NP, Williamson JD, McNeil JJ, Murray AM, Newman AB.
PMID: 33367621
J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):2007-2014. doi: 10.1093/gerona/glaa316.

BACKGROUND: Cerebrovascular events, dementia, and cancer can contribute to physical disability with activities of daily living (ADL). It is unclear whether low-dose aspirin reduces this burden in aging populations. In a secondary analysis, we now examine aspirin's effects on...

Nanoparticle Delivery in Prostate Tumors Implanted in Mice Facilitated by Either Local or Whole-Body Heating.

Fluids (Basel, Switzerland)

Gu Q, Dockery L, Daniel MC, Bieberich CJ, Ma R, Zhu L.
PMID: 34651038
Fluids (Basel). 2021 Aug;6(8). doi: 10.3390/fluids6080272.

This work discusses in vivo experiments that were performed to evaluate whether local or whole-body heating to 40 °C reduced interstitial fluid pressures (IFPs) and enhanced nanoparticle delivery to subcutaneous PC3 human prostate cancer xenograft tumors in mice. After...

Journal of medical genetics

Fadaie Z, Whelan L, Dockery A, Li CHZ, van den Born LI, Hoyng CB, Gilissen C, Corominas J, Rowlands C, Megaw R, Lampe AK, Cremers FPM, Farrar GJ, Ellingford JM, Kenna PF, Roosing S.
PMID: 33910932
J Med Genet. 2021 Apr 28; doi: 10.1136/jmedgenet-2020-107626. Epub 2021 Apr 28.

BACKGROUND: Inherited retinal diseases (IRDs) can be caused by variants in >270 genes. The Bardet-Biedl syndrome 1 (METHODS: Whole genome sequencing was performed for three unrelated monoallelic RESULTS: Clinical assessments of probands showed that all individuals displayed non-syndromic RP...

State of Constant Readiness: Lessons Learned From the Military.

Nurse leader

Sikes DL, Dockery JM, Fields A, Batcheller J, Opton L.
PMID: 34493932
Nurse Lead. 2021 Sep 03; doi: 10.1016/j.mnl.2021.08.004. Epub 2021 Sep 03.

The purpose of this article is to compare and discuss the preparation of civilian and military nurses in meeting the demands of the COVID-19 pandemic. The military nursing system exemplifies a program of ongoing training and evaluations to prepare...

An actuatable soft reservoir modulates host foreign body response.

Science robotics

Dolan EB, Varela CE, Mendez K, Whyte W, Levey RE, Robinson ST, Maye E, O'Dwyer J, Beatty R, Rothman A, Fan Y, Hochstein J, Rothenbucher SE, Wylie R, Starr JR, Monaghan M, Dockery P, Duffy GP, Roche ET.
PMID: 33137787
Sci Robot. 2019 Aug 28;4(33). doi: 10.1126/scirobotics.aax7043.

The performance of indwelling medical devices that depend on an interface with soft tissue is plagued by complex, unpredictable foreign body responses. Such devices-including breast implants, biosensors, and drug delivery devices-are often subject to a collection of biological host...

Correction: Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammation.

The Journal of biological chemistry

Rowley SM, Kuriakose T, Dockery LM, Tran-Nguyen T, Gingerich AD, Wei L, Watford WT.
PMID: 32471852
J Biol Chem. 2020 May 29;295(22):7812. doi: 10.1074/jbc.AAC120.014105.

No abstract available.

Role of exposure databases in epidemiology.

Archives of environmental health

Matanoski G, Selevan SG, Akland G, Bornschein RL, Dockery D, Edmonds L, Greife A, Mehlman M, Shaw GM, Elliott E.
PMID: 1485807
Arch Environ Health. 1992 Nov-Dec;47(6):439-46. doi: 10.1080/00039896.1992.9938385.

At present, exposure databases record data primarily for regulatory purposes; they have not focused on serving the needs of epidemiologists or public health. However, the modification of exposure databases could facilitate their use in epidemiology. Characteristics necessary to enhance...

Strong beaming of microwave surface waves with complementary split-ring-resonator arrays.

Scientific reports

Young E, Dockrey JA, Hibbins AP, Sambles JR, Lawrence CR.
PMID: 30108267
Sci Rep. 2018 Aug 14;8(1):12102. doi: 10.1038/s41598-018-30555-x.

A thin copper sheet, populated by an array of complementary split ring resonators, presents strong surface wave beaming in orthogonal directions at two distinct frequencies. This simple array is significantly thinner than existing single frequency beaming surfaces. The observed...

Showing 13 to 24 of 94 entries