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Showing 13 to 24 of 49 entries
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Observation of resonant enhancement of photoinduced second-harmonic generation in Tm-doped aluminosilicate glass fibers.

Optics letters

Krol DM, Digiovanni DJ, Pleibel W, Stolen RH.
PMID: 19823338
Opt Lett. 1993 Aug 01;18(15):1220-2. doi: 10.1364/ol.18.001220.

We report a 10(3) increase in efficiency of second-harmonic generation in Tm(3+)-doped aluminosilicate glass fibers when the wavelength of the fundamental beam is tuned to the maximum of the (3)H(6) ? (3)F(4) absorption of Tm(3+) at 785 nm. This...

Annular erbium-ion distribution for ruggedized optical fiber amplifiers.

Optics letters

Vengsarkar AM, Digiovanni DJ, Walker KL, Federici JF.
PMID: 19823322
Opt Lett. 1993 Jul 15;18(14):1165. doi: 10.1364/ol.18.001165.

No abstract available.

Predicting and Quantifying Antagonistic Effects of Natural Compounds Given with Chemotherapeutic Agents: Applications for High-Throughput Screening.

Cancers

Hackman GL, Collins M, Lu X, Lodi A, DiGiovanni J, Tiziani S.
PMID: 33322034
Cancers (Basel). 2020 Dec 10;12(12). doi: 10.3390/cancers12123714.

Natural products have been used for centuries to treat various human ailments. In recent decades, multi-drug combinations that utilize natural products to synergistically enhance the therapeutic effects of cancer drugs have been identified and have shown success in improving...

Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.

Molecular therapy : the journal of the American Society of Gene Therapy

Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, Macias E.
PMID: 34450249
Mol Ther. 2021 Aug 25; doi: 10.1016/j.ymthe.2021.08.029. Epub 2021 Aug 25.

Serine/threonine kinase 3 (STK3) is an essential member of the highly conserved Hippo tumor suppressor pathway that regulates Yes-associated protein 1 (YAP1) and TAZ. STK3 and its paralog STK4 initiate a phosphorylation cascade that regulates YAP1/TAZ inhibition and degradation,...

Thyroid nodules in xeroderma pigmentosum patients: a feature of premature aging.

Journal of endocrinological investigation

Kouatcheu SD, Marko J, Tamura D, Khan SG, Lee CR, DiGiovanna JJ, Kraemer KH.
PMID: 33155181
J Endocrinol Invest. 2021 Jul;44(7):1475-1482. doi: 10.1007/s40618-020-01451-x. Epub 2020 Nov 05.

PURPOSE: Xeroderma pigmentosum (XP) is an autosomal recessive disease with defective DNA repair, a markedly increased risk of skin cancer, and premature aging. Reports from North Africa have described thyroid nodules in XP patients, but thyroid nodule prevalence has...

800Gb/s (8x128Gb/s) unrepeatered transmission over 515-km large-area ultra-low-loss fiber using 2nd-order Raman pumping.

Optics express

Zhu B, Borel PI, Geisler T, Jensen R, Leng L, Jiang X, Peckham DW, Lingle RL, Vaidya D, Yan MF, Wisk PW, DiGiovanni DJ.
PMID: 27828467
Opt Express. 2016 Oct 31;24(22):25291-25297. doi: 10.1364/OE.24.025291.

We demonstrate unrepeatered transmission of 8x128Gb/s PDM-QPSK signals over a 515k-m fiber link. This ultra-long distance of 800 Gb/s unrepeatered transmission in a single fiber configuration is achieved by employing enabling techniques such as large-effective-area ultra-low-attenuation fibers, co-propagating and...

Metronidazole-Induced Hepatitis in a Teenager With Xeroderma Pigmentosum and Trichothiodystrophy Overlap.

Pediatrics

Abiona A, Cordeiro N, Fawcett H, Tamura D, Khan SG, DiGiovanna JJ, Lehmann AR, Fassihi H.
PMID: 34593652
Pediatrics. 2021 Oct;148(4). doi: 10.1542/peds.2021-050360. Epub 2021 Sep 30.

A teenage girl had the rare combined phenotype of xeroderma pigmentosum and trichothiodystrophy, resulting from mutations in the XPD (ERCC2) gene involved in nucleotide excision repair (NER). After treatment with antibiotics, including metronidazole for recurrent infections, she showed signs...

Photo-induced SNAP: fabrication, trimming, and tuning of microresonator chains.

Optics express

Sumetsky M, DiGiovanni DJ, Dulashko Y, Liu X, Monberg EM, Taunay TF.
PMID: 22565693
Opt Express. 2012 May 07;20(10):10684-91. doi: 10.1364/OE.20.010684.

We introduce multiple series of uncoupled and coupled surface nanoscale axial photonics (SNAP) microresonators along the 30 micron diameter germanium-doped photosensitive silica optical fiber and demonstrate their permanent trimming and temporary tuning with a CO2 laser and a wire...

All-optical switching and multifrequency generation in a dual-core photonic crystal fiber.

Optics letters

Betlej A, Suntsov S, Makris KG, Jankovic L, Christodoulides DN, Stegeman GI, Fini J, Bise RT, Digiovanni DJ.
PMID: 16642145
Opt Lett. 2006 May 15;31(10):1480-2. doi: 10.1364/ol.31.001480.

We demonstrate all-optical switching at 1550 nm between two weakly coupled cores in a photonic crystal fiber for intensities up to 0.5 TW/cm2. Spectrum analysis at higher intensities reveals that the output was dominated by continuum generation primarily towards...

Optically driven deposition of single-walled carbon-nanotube saturable absorbers on optical fiber end-faces.

Optics express

Nicholson JW, Windeler RS, Digiovanni DJ.
PMID: 19547259
Opt Express. 2007 Jul 23;15(15):9176-83. doi: 10.1364/oe.15.009176.

Optical radiation propagating in a fiber is used to deposit commercially available, single-walled carbon nanotubes on cleaved optical fiber end faces and fiber connectors. Thermophoresis caused by heating due to optical absorption is considered to be a likely candidate...

High-power broadband Yb-free clad-pumped EDFA for L-band DWDM applications.

Optics letters

Zhu B, Law M, Rooney J, Shenk S, Yan MF, DiGiovanni DJ.
PMID: 24365825
Opt Lett. 2014 Jan 01;39(1):72-5. doi: 10.1364/OL.39.000072.

We demonstrated high-power broadband Yb-free clad-pumped erbium-doped fiber amplifier (EDFA) using commercial available low-cost 976 nm multimode diodes. An output power +33 dBm with less than ±1 dB natural gain flatness over a gain bandwidth of 33 nm (1570.3-1603.3...

Neural Network Model of Vestibular Nuclei Reaction to Onset of Vestibular Prosthetic Stimulation.

Frontiers in bioengineering and biotechnology

DiGiovanna J, Nguyen TA, Guinand N, Pérez-Fornos A, Micera S.
PMID: 27148528
Front Bioeng Biotechnol. 2016 Apr 20;4:34. doi: 10.3389/fbioe.2016.00034. eCollection 2016.

The vestibular system incorporates multiple sensory pathways to provide crucial information about head and body motion. Damage to the semicircular canals, the peripheral vestibular organs that sense rotational velocities of the head, can severely degrade the ability to perform...

Showing 13 to 24 of 49 entries