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Low Tenofovir Plasma Exposure in HIV Oral Pre-exposure Prophylaxis Recipients with Gastrointestinal Disorders.

Antimicrobial agents and chemotherapy

Calcagno A, Dal Conte I, Cattaneo D, Testi R, Mistrangelo M, Gervasoni C, de Nicolò A, Bonora S, D'Avolio A, Di Perri G.
PMID: 33106270
Antimicrob Agents Chemother. 2020 Oct 26; doi: 10.1128/AAC.01902-20. Epub 2020 Oct 26.

Four pre-exposure prophylaxis (PrEP) users with gastro-intestinal disorders (sleeve gastrectomy, terminal ileitis, celiac disease or chronic diarrhea) and receiving oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) were included. Despite a self-reported high adherence, trough plasma tenofovir concentrations (after a supervised intake)...

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Calcagno A, Dal Conte I, Cattaneo D, et al. Low Tenofovir Plasma Exposure in HIV Oral Pre-exposure Prophylaxis Recipients with Gastrointestinal Disorders. Antimicrob Agents Chemother. 2020;doi: 10.1128/AAC.01902-20.
Calcagno, A., Dal Conte, I., Cattaneo, D., Testi, R., Mistrangelo, M., Gervasoni, C., de Nicolò, A., Bonora, S., D'Avolio, A., & Di Perri, G. (2020). Low Tenofovir Plasma Exposure in HIV Oral Pre-exposure Prophylaxis Recipients with Gastrointestinal Disorders. Antimicrobial agents and chemotherapy, . https://doi.org/10.1128/AAC.01902-20
Calcagno, Andrea, et al. "Low Tenofovir Plasma Exposure in HIV Oral Pre-exposure Prophylaxis Recipients with Gastrointestinal Disorders." Antimicrobial agents and chemotherapy vol. (2020). doi: https://doi.org/10.1128/AAC.01902-20
Calcagno A, Dal Conte I, Cattaneo D, Testi R, Mistrangelo M, Gervasoni C, de Nicolò A, Bonora S, D'Avolio A, Di Perri G. Low Tenofovir Plasma Exposure in HIV Oral Pre-exposure Prophylaxis Recipients with Gastrointestinal Disorders. Antimicrob Agents Chemother. 2020 Oct 26; doi: 10.1128/AAC.01902-20. Epub 2020 Oct 26. PMID: 33106270; PMCID: PMC7927807.
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Serology for .

Life (Basel, Switzerland)

Stroffolini G, Segala FV, Lupia T, Faraoni S, Rossi L, Tomassone L, Zanet S, De Rosa FG, Di Perri G, Calcagno A.
PMID: 34947841
Life (Basel). 2021 Nov 27;11(12). doi: 10.3390/life11121310.

Ticks are hematophagous parasites that can transmit a variety of human pathogens, and their life cycle is dependent on several climatic factors for development and survival. We conducted a study in Piedmont and Aosta Valley, Italy, between 2009 and...

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Stroffolini G, Segala FV, Lupia T, et al. Serology for . Life (Basel). 2021;11(12)doi: 10.3390/life11121310.
Stroffolini, G., Segala, F. V., Lupia, T., Faraoni, S., Rossi, L., Tomassone, L., Zanet, S., De Rosa, F. G., Di Perri, G., & Calcagno, A. (2021). Serology for . Life (Basel, Switzerland), 11(12), . https://doi.org/10.3390/life11121310
Stroffolini, Giacomo, et al. "Serology for ." Life (Basel, Switzerland) vol. 11,12 (2021). doi: https://doi.org/10.3390/life11121310
Stroffolini G, Segala FV, Lupia T, Faraoni S, Rossi L, Tomassone L, Zanet S, De Rosa FG, Di Perri G, Calcagno A. Serology for . Life (Basel). 2021 Nov 27;11(12). doi: 10.3390/life11121310. PMID: 34947841.
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Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers.

Vaccines

Trunfio M, Verga F, Ghisetti V, Burdino E, Emanuele T, Bonora S, Di Perri G, Calcagno A.
PMID: 34960123
Vaccines (Basel). 2021 Nov 23;9(12). doi: 10.3390/vaccines9121377.

We evaluated the clinical protection of BNT162b2 mRNA vaccine in healthcare workers (HCWs) and how COVID-19 manifestations and contagiousness change as the time since first dose increases. A matched (1:2 ratio) parallel cohort study was performed. During the first...

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Trunfio M, Verga F, Ghisetti V, et al. Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers. Vaccines (Basel). 2021;9(12)doi: 10.3390/vaccines9121377.
Trunfio, M., Verga, F., Ghisetti, V., Burdino, E., Emanuele, T., Bonora, S., Di Perri, G., & Calcagno, A. (2021). Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers. Vaccines, 9(12), . https://doi.org/10.3390/vaccines9121377
Trunfio, Mattia, et al. "Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers." Vaccines vol. 9,12 (2021). doi: https://doi.org/10.3390/vaccines9121377
Trunfio M, Verga F, Ghisetti V, Burdino E, Emanuele T, Bonora S, Di Perri G, Calcagno A. Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers. Vaccines (Basel). 2021 Nov 23;9(12). doi: 10.3390/vaccines9121377. PMID: 34960123; PMCID: PMC8705309.
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Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV.

AIDS and behavior

Trunfio M, De Francesco D, Vai D, Medina C, Milesi M, Domini S, Alcantarini C, Imperiale D, Bonora S, Di Perri G, Calcagno A.
PMID: 34982319
AIDS Behav. 2022 Jan 04; doi: 10.1007/s10461-021-03563-8. Epub 2022 Jan 04.

Aging and increased cardiovascular risk are major drivers for HIV-associated neurocognitive disorders (HAND), for which accurate screenings are lacking. Mini-Addenbrooke's Cognitive Examination (MACE) reliably detects vascular and neurodegenerative cognitive decline among HIV-negative patients. We evaluated MACE diagnostic accuracy in...

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Trunfio M, De Francesco D, Vai D, et al. Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV. AIDS Behav. 2022;doi: 10.1007/s10461-021-03563-8.
Trunfio, M., De Francesco, D., Vai, D., Medina, C., Milesi, M., Domini, S., Alcantarini, C., Imperiale, D., Bonora, S., Di Perri, G., & Calcagno, A. (2022). Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV. AIDS and behavior, . https://doi.org/10.1007/s10461-021-03563-8
Trunfio, Mattia, et al. "Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV." AIDS and behavior vol. (2022). doi: https://doi.org/10.1007/s10461-021-03563-8
Trunfio M, De Francesco D, Vai D, Medina C, Milesi M, Domini S, Alcantarini C, Imperiale D, Bonora S, Di Perri G, Calcagno A. Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV. AIDS Behav. 2022 Jan 04; doi: 10.1007/s10461-021-03563-8. Epub 2022 Jan 04. PMID: 34982319.
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Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy.

Journal of the International AIDS Society

Cozzi-Lepri A, Lo Caputo S, Maggiolo F, Antinori A, Ammassari A, Marchetti G, Mastroianni C, Gori A, Di Perri G, Angarano G, Carbone A, Monforte Ad.
PMID: 25397519
J Int AIDS Soc. 2014 Nov 02;17(4):19775. doi: 10.7448/IAS.17.4.19775. eCollection 2014.

INTRODUCTION: Emtricitabine/rilpivirine/tenofovir (EVP) is a fixed-dose combination of antiretrovirals (ARV) approved by the European Medicines Agency in November 2011 and introduced in Italy in February 2013. It is a once-a-day single tablet and is licensed in Europe for use...

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Cozzi-Lepri A, Lo Caputo S, Maggiolo F, et al. Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy. J Int AIDS Soc. 2014;17(4):19775doi: 10.7448/IAS.17.4.19775.
Cozzi-Lepri, A., Lo Caputo, S., Maggiolo, F., Antinori, A., Ammassari, A., Marchetti, G., Mastroianni, C., Gori, A., Di Perri, G., Angarano, G., Carbone, A., Monforte, A. d. (2014). Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy. Journal of the International AIDS Society, 17(4), 19775. https://doi.org/10.7448/IAS.17.4.19775
Cozzi-Lepri, Alessandro, et al. "Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy." Journal of the International AIDS Society vol. 17,4 (2014): 19775. doi: https://doi.org/10.7448/IAS.17.4.19775
Cozzi-Lepri A, Lo Caputo S, Maggiolo F, Antinori A, Ammassari A, Marchetti G, Mastroianni C, Gori A, Di Perri G, Angarano G, Carbone A, Monforte Ad. Determinants of use of the fixed dose combination emtricitabine/rilpivirine/tenofovir (Eviplera) in HIV-infected persons receiving care in Italy. J Int AIDS Soc. 2014 Nov 02;17(4):19775. doi: 10.7448/IAS.17.4.19775. eCollection 2014. PMID: 25397519; PMCID: PMC4225399.
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Erratum to: Cortical reorganization in an astronaut's brain after long-duration spaceflight.

Brain structure & function

Demertzi A, Van Ombergen A, Tomilovskaya E, Jeurissen B, Pechenkova E, Di Perri C, Litvinova L, Amico E, Rumshiskaya A, Rukavishnikov I, Sijbers J, Sinitsyn V, Kozlovskaya IB, Sunaert S, Parizel PM, Van de Heyning PH, Laureys S, Wuyts FL.
PMID: 27084748
Brain Struct Funct. 2016 Jun;221(5):2877. doi: 10.1007/s00429-016-1209-x.

No abstract available.

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Demertzi A, Van Ombergen A, Tomilovskaya E, et al. Erratum to: Cortical reorganization in an astronaut's brain after long-duration spaceflight. Brain Struct Funct. 2016;221(5):2877doi: 10.1007/s00429-016-1209-x.
Demertzi, A., Van Ombergen, A., Tomilovskaya, E., Jeurissen, B., Pechenkova, E., Di Perri, C., Litvinova, L., Amico, E., Rumshiskaya, A., Rukavishnikov, I., Sijbers, J., Sinitsyn, V., Kozlovskaya, I. B., Sunaert, S., Parizel, P. M., Van de Heyning, P. H., Laureys, S., & Wuyts, F. L. (2016). Erratum to: Cortical reorganization in an astronaut's brain after long-duration spaceflight. Brain structure & function, 221(5), 2877. https://doi.org/10.1007/s00429-016-1209-x
Demertzi, Athena, et al. "Erratum to: Cortical reorganization in an astronaut's brain after long-duration spaceflight." Brain structure & function vol. 221,5 (2016): 2877. doi: https://doi.org/10.1007/s00429-016-1209-x
Demertzi A, Van Ombergen A, Tomilovskaya E, Jeurissen B, Pechenkova E, Di Perri C, Litvinova L, Amico E, Rumshiskaya A, Rukavishnikov I, Sijbers J, Sinitsyn V, Kozlovskaya IB, Sunaert S, Parizel PM, Van de Heyning PH, Laureys S, Wuyts FL. Erratum to: Cortical reorganization in an astronaut's brain after long-duration spaceflight. Brain Struct Funct. 2016 Jun;221(5):2877. doi: 10.1007/s00429-016-1209-x. PMID: 27084748; PMCID: PMC4969885.
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Cerebrospinal fluid biomarkers in patients with plasma HIV RNA below 20 copies/mL.

Journal of the International AIDS Society

Calcagno A, Atzori C, Romito A, Ecclesia S, Imperiale D, Audagnotto S, Alberione MC, Trentalange A, Di Perri G, Bonora S.
PMID: 25397465
J Int AIDS Soc. 2014 Nov 02;17(4):19719. doi: 10.7448/IAS.17.4.19719. eCollection 2014.

INTRODUCTION: Low level HIV-1 CSF replication (CsfLLV) is often found even in patients with controlled plasma viraemia. The clinical consequences of such finding are uncertain; however, both symptomatic neurological disturbances and neurocognitive disorders may arise in the context of...

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Calcagno A, Atzori C, Romito A, et al. Cerebrospinal fluid biomarkers in patients with plasma HIV RNA below 20 copies/mL. J Int AIDS Soc. 2014;17(4):19719doi: 10.7448/IAS.17.4.19719.
Calcagno, A., Atzori, C., Romito, A., Ecclesia, S., Imperiale, D., Audagnotto, S., Alberione, M. C., Trentalange, A., Di Perri, G., & Bonora, S. (2014). Cerebrospinal fluid biomarkers in patients with plasma HIV RNA below 20 copies/mL. Journal of the International AIDS Society, 17(4), 19719. https://doi.org/10.7448/IAS.17.4.19719
Calcagno, Andrea, et al. "Cerebrospinal fluid biomarkers in patients with plasma HIV RNA below 20 copies/mL." Journal of the International AIDS Society vol. 17,4 (2014): 19719. doi: https://doi.org/10.7448/IAS.17.4.19719
Calcagno A, Atzori C, Romito A, Ecclesia S, Imperiale D, Audagnotto S, Alberione MC, Trentalange A, Di Perri G, Bonora S. Cerebrospinal fluid biomarkers in patients with plasma HIV RNA below 20 copies/mL. J Int AIDS Soc. 2014 Nov 02;17(4):19719. doi: 10.7448/IAS.17.4.19719. eCollection 2014. PMID: 25397465; PMCID: PMC4225354.
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Carbapenemase-Producing .

Microorganisms

Pagani N, Corcione S, Lupia T, Scabini S, Filippini C, Angilletta R, Shbaklo N, Mornese Pinna S, Romagnoli R, Biancone L, Cavallo R, Di Perri G, Solidoro P, Boffini M, De Rosa FG.
PMID: 34835398
Microorganisms. 2021 Oct 31;9(11). doi: 10.3390/microorganisms9112272.

Carbapenemase-KPC producing

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Pagani N, Corcione S, Lupia T, et al. Carbapenemase-Producing . Microorganisms. 2021;9(11)doi: 10.3390/microorganisms9112272.
Pagani, N., Corcione, S., Lupia, T., Scabini, S., Filippini, C., Angilletta, R., Shbaklo, N., Mornese Pinna, S., Romagnoli, R., Biancone, L., Cavallo, R., Di Perri, G., Solidoro, P., Boffini, M., & De Rosa, F. G. (2021). Carbapenemase-Producing . Microorganisms, 9(11), . https://doi.org/10.3390/microorganisms9112272
Pagani, Nicole, et al. "Carbapenemase-Producing ." Microorganisms vol. 9,11 (2021). doi: https://doi.org/10.3390/microorganisms9112272
Pagani N, Corcione S, Lupia T, Scabini S, Filippini C, Angilletta R, Shbaklo N, Mornese Pinna S, Romagnoli R, Biancone L, Cavallo R, Di Perri G, Solidoro P, Boffini M, De Rosa FG. Carbapenemase-Producing . Microorganisms. 2021 Oct 31;9(11). doi: 10.3390/microorganisms9112272. PMID: 34835398; PMCID: PMC8626028.
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[Surviving the suicide of a loved one: impact and postvention.].

Recenti progressi in medicina

Pontiggia M, Di Pierro R, Madeddu F, Calati R.
PMID: 34782808
Recenti Prog Med. 2021 Nov;112(11):728-741. doi: 10.1701/3696.36851.

Suicide is a public health problem having important consequences also for people who survive to the suicide of a loved one - the suicide loss survivors. Since suicide bereavement can have a lasting and significant psychosocial impact on the...

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Pontiggia M, Di Pierro R, Madeddu F, et al. Sopravvivere al suicidio di una persona cara: impatto e interventi di supporto per i sopravvissuti (postvention). [Surviving the suicide of a loved one: impact and postvention.]. Recenti Prog Med. 2021;112(11):728-741doi: 10.1701/3696.36851.
Pontiggia, M., Di Pierro, R., Madeddu, F., & Calati, R. (2021). Sopravvivere al suicidio di una persona cara: impatto e interventi di supporto per i sopravvissuti (postvention). [Surviving the suicide of a loved one: impact and postvention.]. Recenti progressi in medicina, 112(11), 728-741. https://doi.org/10.1701/3696.36851
Pontiggia, Martina, et al. "Sopravvivere al suicidio di una persona cara: impatto e interventi di supporto per i sopravvissuti (postvention)." [Surviving the suicide of a loved one: impact and postvention.]. Recenti progressi in medicina vol. 112,11 (2021): 728-741. doi: https://doi.org/10.1701/3696.36851
Pontiggia M, Di Pierro R, Madeddu F, Calati R. Sopravvivere al suicidio di una persona cara: impatto e interventi di supporto per i sopravvissuti (postvention). [Surviving the suicide of a loved one: impact and postvention.]. Recenti Prog Med. 2021 Nov;112(11):728-741. doi: 10.1701/3696.36851. Italian. PMID: 34782808.
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Alzheimer Dementia in People Living With HIV.

Neurology. Clinical practice

Calcagno A, Celani L, Trunfio M, Orofino G, Imperiale D, Atzori C, Arena V, d'Ettorre G, Guaraldi G, Gisslen M, Di Perri G.
PMID: 34840876
Neurol Clin Pract. 2021 Oct;11(5):e627-e633. doi: 10.1212/CPJ.0000000000001060.

OBJECTIVE: Given the aging of people living with HIV (PLWH) and the high prevalence of HIV-associated neurocognitive disorders, we aimed at describing the clinical, instrumental, and CSF features of PLWH diagnosed with Alzheimer dementia (AD).METHODS: The databases of 3...

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Calcagno A, Celani L, Trunfio M, et al. Alzheimer Dementia in People Living With HIV. Neurol Clin Pract. 2021;11(5):e627-e633doi: 10.1212/CPJ.0000000000001060.
Calcagno, A., Celani, L., Trunfio, M., Orofino, G., Imperiale, D., Atzori, C., Arena, V., d'Ettorre, G., Guaraldi, G., Gisslen, M., & Di Perri, G. (2021). Alzheimer Dementia in People Living With HIV. Neurology. Clinical practice, 11(5), e627-e633. https://doi.org/10.1212/CPJ.0000000000001060
Calcagno, Andrea, et al. "Alzheimer Dementia in People Living With HIV." Neurology. Clinical practice vol. 11,5 (2021): e627-e633. doi: https://doi.org/10.1212/CPJ.0000000000001060
Calcagno A, Celani L, Trunfio M, Orofino G, Imperiale D, Atzori C, Arena V, d'Ettorre G, Guaraldi G, Gisslen M, Di Perri G. Alzheimer Dementia in People Living With HIV. Neurol Clin Pract. 2021 Oct;11(5):e627-e633. doi: 10.1212/CPJ.0000000000001060. PMID: 34840876; PMCID: PMC8610525.
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Nonsuicidal self-injury as an affect-regulation strategy and the moderating role of impulsivity.

Child and adolescent mental health

Di Pierro R, Sarno I, Gallucci M, Madeddu F.
PMID: 32878353
Child Adolesc Ment Health. 2014 Nov;19(4):259-264. doi: 10.1111/camh.12063. Epub 2014 Apr 18.

BACKGROUND: Nonsuicidal self-injury (NSSI) is used to cope with negative affect states. We investigated the association between impulsivity and this affect-regulation process.METHOD: Affect states associated with NSSI and impulsivity traits were evaluated in 30 Italian adolescent self-injurers (63.3% female,...

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Di Pierro R, Sarno I, Gallucci M, et al. Nonsuicidal self-injury as an affect-regulation strategy and the moderating role of impulsivity. Child Adolesc Ment Health. 2014;19(4):259-264doi: 10.1111/camh.12063.
Di Pierro, R., Sarno, I., Gallucci, M., & Madeddu, F. (2014). Nonsuicidal self-injury as an affect-regulation strategy and the moderating role of impulsivity. Child and adolescent mental health, 19(4), 259-264. https://doi.org/10.1111/camh.12063
Di Pierro, Rossella, et al. "Nonsuicidal self-injury as an affect-regulation strategy and the moderating role of impulsivity." Child and adolescent mental health vol. 19,4 (2014): 259-264. doi: https://doi.org/10.1111/camh.12063
Di Pierro R, Sarno I, Gallucci M, Madeddu F. Nonsuicidal self-injury as an affect-regulation strategy and the moderating role of impulsivity. Child Adolesc Ment Health. 2014 Nov;19(4):259-264. doi: 10.1111/camh.12063. Epub 2014 Apr 18. PMID: 32878353.
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Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia.

British journal of clinical pharmacology

Corcione S, De Nicolò A, Montrucchio G, Scabini S, Avataneo V, Bonetto C, Mornese Pinna S, Cusato J, Canta F, Urbino R, Di Perri G, Brazzi L, De Rosa FG, D'Avolio A.
PMID: 33990984
Br J Clin Pharmacol. 2021 May 14; doi: 10.1111/bcp.14895. Epub 2021 May 14.

Remdesivir is one of the most encouraging treatments against SARS-CoV-2 infection. After intravenous infusion, RDV is rapidly metabolized (t

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Corcione S, De Nicolò A, Montrucchio G, et al. Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia. Br J Clin Pharmacol. 2021;doi: 10.1111/bcp.14895.
Corcione, S., De Nicolò, A., Montrucchio, G., Scabini, S., Avataneo, V., Bonetto, C., Mornese Pinna, S., Cusato, J., Canta, F., Urbino, R., Di Perri, G., Brazzi, L., De Rosa, F. G., & D'Avolio, A. (2021). Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia. British journal of clinical pharmacology, . https://doi.org/10.1111/bcp.14895
Corcione, Silvia, et al. "Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia." British journal of clinical pharmacology vol. (2021). doi: https://doi.org/10.1111/bcp.14895
Corcione S, De Nicolò A, Montrucchio G, Scabini S, Avataneo V, Bonetto C, Mornese Pinna S, Cusato J, Canta F, Urbino R, Di Perri G, Brazzi L, De Rosa FG, D'Avolio A. Real-life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID-19 pneumonia. Br J Clin Pharmacol. 2021 May 14; doi: 10.1111/bcp.14895. Epub 2021 May 14. PMID: 33990984; PMCID: PMC8239594.
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