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Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion.

Genes & development

Wu CT, Hilgendorf KI, Bevacqua RJ, Hang Y, Demeter J, Kim SK, Jackson PK.
PMID: 34385262
Genes Dev. 2021 Sep 01;35(17):1243-1255. doi: 10.1101/gad.348261.121. Epub 2021 Aug 12.

Multiple G protein-coupled receptors (GPCRs) are expressed in pancreatic islet cells, but the majority have unknown functions. We observed specific GPCRs localized to primary cilia, a prominent signaling organelle, in pancreatic α and β cells. Loss of cilia disrupts...

Cite
Wu CT, Hilgendorf KI, Bevacqua RJ, et al. Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion. Genes Dev. 2021;35(17):1243-1255doi: 10.1101/gad.348261.121.
Wu, C. T., Hilgendorf, K. I., Bevacqua, R. J., Hang, Y., Demeter, J., Kim, S. K., & Jackson, P. K. (2021). Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion. Genes & development, 35(17), 1243-1255. https://doi.org/10.1101/gad.348261.121
Wu, Chien-Ting, et al. "Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion." Genes & development vol. 35,17 (2021): 1243-1255. doi: https://doi.org/10.1101/gad.348261.121
Wu CT, Hilgendorf KI, Bevacqua RJ, Hang Y, Demeter J, Kim SK, Jackson PK. Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion. Genes Dev. 2021 Sep 01;35(17):1243-1255. doi: 10.1101/gad.348261.121. Epub 2021 Aug 12. PMID: 34385262; PMCID: PMC8415323.
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Showing 145 to 145 of 145 entries