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Showing 421 to 430 of 430 entries
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VolterraNet: A Higher Order Convolutional Network With Group Equivariance for Homogeneous Manifolds.

IEEE transactions on pattern analysis and machine intelligence

Banerjee M, Chakraborty R, Bouza J, Vemuri BC.
PMID: 33147684
IEEE Trans Pattern Anal Mach Intell. 2022 Feb;44(2):823-833. doi: 10.1109/TPAMI.2020.3035130. Epub 2022 Jan 07.

Convolutional neural networks have been highly successful in image-based learning tasks due to their translation equivariance property. Recent work has generalized the traditional convolutional layer of a convolutional neural network to non-euclidean spaces and shown group equivariance of the...

Chronic unilateral arm lymphedema correlates with increased intima-media thickness in the brachial artery.

VASA. Zeitschrift fur Gefasskrankheiten

Klüsch V, Boyle EC, Rustum S, Franz M, Park-Simon TW, Haverich A, Bara C.
PMID: 34872377
Vasa. 2022 Jan;51(1):19-23. doi: 10.1024/0301-1526/a000982. Epub 2021 Dec 07.

No abstract available.

Multi-country clinical outcomes of a new nondiffractive presbyopia-correcting intraocular lens.

Journal of cataract and refractive surgery

Bala C, Poyales F, Guarro M, Mesa RR, Mearza A, Varma DK, Jasti S, Lemp-Hull J.
PMID: 34288635
J Cataract Refract Surg. 2021 Jun 11; doi: 10.1097/j.jcrs.0000000000000712. Epub 2021 Jun 11.

PURPOSE: To evaluate the effectiveness and safety of a novel presbyopia-correcting intraocular lens (IOL) with a nondiffractive design, DFT015, compared with an aspheric monofocal IOL, SN60WF.SETTING: Nineteen investigational sites in four countries: Australia, Canada, Spain, and the United Kingdom.DESIGN:...

Evaluation of in vitro/in vivo correlations for three fentanyl transdermal delivery systems using in vitro skin permeation testing and human pharmacokinetic studies under the influence of transient heat application.

Journal of controlled release : official journal of the Controlled Release Society

Shin SH, Yu M, Hammell DC, Ghosh P, Raney SG, Hassan HE, Stinchcomb AL.
PMID: 34838928
J Control Release. 2021 Nov 25; doi: 10.1016/j.jconrel.2021.11.030. Epub 2021 Nov 25.

The value of developing an in vitro/in vivo correlation (IVIVC) is substantial in biopharmaceutical drug development because once the model is developed and validated, an in vitro method may be used to efficiently assess and predict drug product performance...

Integrative Analysis of Gene-Specific DNA Methylation and Untargeted Metabolomics Data from the ELEMENT Cohort.

Epigenetics insights

Goodrich JM, Hector EC, Tang L, LaBarre JL, Dolinoy DC, Mercado-Garcia A, Cantoral A, Song PX, Téllez-Rojo MM, Peterson KE.
PMID: 33354655
Epigenet Insights. 2020 Dec 10;13:2516865720977888. doi: 10.1177/2516865720977888. eCollection 2020.

Epigenetic modifications, such as DNA methylation, influence gene expression and cardiometabolic phenotypes that are manifest in developmental periods in later life, including adolescence. Untargeted metabolomics analysis provide a comprehensive snapshot of physiological processes and metabolism and have been related...

Transcatheter Aortic Valve Replacement With Self-Expandable Supra-Annular Valves for Degenerated Surgical Bioprostheses: Insights From Transcatheter Valve Therapy Registry.

Journal of the American Heart Association

Dallan LAP, Forrest JK, Reardon MJ, Szeto WY, George I, Kodali S, Kleiman NS, Yakubov SJ, Grubb KJ, Liu F, Baeza C, Attizzani GF.
PMID: 34514840
J Am Heart Assoc. 2021 Sep 21;10(18):e021871. doi: 10.1161/JAHA.121.021871. Epub 2021 Sep 13.

Background Transcatheter aortic valve replacement with supra-annular transcatheter heart valves has been adopted in patients with degenerated surgical aortic valves. The next generation self-expanding Evolut PRO valve has not been evaluated in patients with surgical valve failure. Methods and...

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.

European urology

Darst BF, Hughley R, Pfennig A, Hazra U, Fan C, Wan P, Sheng X, Xia L, Andrews C, Chen F, Berndt SI, Kote-Jarai Z, Govindasami K, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Huff CD, Strom SS, Isaacs WB, Park JY, Zheng W, Ostrander EA, Walsh PC, Carpten J, Sellers TA, Yamoah K, Murphy AB, Sanderson M, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas C, Kittles RA, Xu J, Stern MC, Chokkalingam AP, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Kibel AS, Klein EA, Goodman PJ, Stanford JL, Drake BF, Hu JJ, Clark PE, Blanchet P, Casey G, Hennis AJM, Lubwama A, Thompson IM, Leach RJ, Gundell SM, Pooler L, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Brureau L, Blot WJ, Biritwum R, Tay E, Truelove A, Niwa S, Tettey Y, Varma R, McKean-Cowdin R, Torres M, Jalloh M, Magueye Gueye S, Niang L, Ogunbiyi O, Oladimeji Idowu M, Popoola O, Adebiyi AO, Aisuodionoe-Shadrach OI, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Yeboah ED, Mensah JE, Anthony Adjei A, Diop H, Cook MB, Chanock SJ, Watya S, Eeles RA, Chiang CWK, Lachance J, Rebbeck TR, Conti DV, Haiman CA.
PMID: 35031163
Eur Urol. 2022 Jan 11; doi: 10.1016/j.eururo.2021.12.023. Epub 2022 Jan 11.

A rare African ancestry-specific germline deletion variant in HOXB13 (X285K, rs77179853) was recently reported in Martinican men with early-onset prostate cancer. Given the role of HOXB13 germline variation in prostate cancer, we investigated the association between HOXB13 X285K and...

MVnet: automated time-resolved tracking of the mitral valve plane in CMR long-axis cine images with residual neural networks: a multi-center, multi-vendor study.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

Gonzales RA, Seemann F, Lamy J, Mojibian H, Atar D, Erlinge D, Steding-Ehrenborg K, Arheden H, Hu C, Onofrey JA, Peters DC, Heiberg E.
PMID: 34857009
J Cardiovasc Magn Reson. 2021 Dec 02;23(1):137. doi: 10.1186/s12968-021-00824-2.

BACKGROUND: Mitral annular plane systolic excursion (MAPSE) and left ventricular (LV) early diastolic velocity (e') are key metrics of systolic and diastolic function, but not often measured by cardiovascular magnetic resonance (CMR). Its derivation is possible with manual, precise...

Evaluation of in vitro/in vivo correlations for three fentanyl transdermal delivery systems using in vitro skin permeation testing and human pharmacokinetic studies under the influence of transient heat application.

Journal of controlled release : official journal of the Controlled Release Society

Shin SH, Yu M, Hammell DC, Ghosh P, Raney SG, Hassan HE, Stinchcomb AL.
PMID: 34838928
J Control Release. 2021 Nov 25;342:134-147. doi: 10.1016/j.jconrel.2021.11.030. Epub 2021 Nov 25.

The value of developing an in vitro/in vivo correlation (IVIVC) is substantial in biopharmaceutical drug development because once the model is developed and validated, an in vitro method may be used to efficiently assess and predict drug product performance...

Maturation and application of phenome-wide association studies.

Trends in genetics : TIG

Liu S, Crawford DC.
PMID: 34991903
Trends Genet. 2022 Jan 03; doi: 10.1016/j.tig.2021.12.002. Epub 2022 Jan 03.

In the past 10 years since its introduction, phenome-wide association studies (PheWAS) have uncovered novel genotype-phenotype relationships. Along the way, PheWAS have evolved in many aspects as a study design with the expanded availability of large data repositories with...

Showing 421 to 430 of 430 entries