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Showing 3169 to 3180 of 3180 entries
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Peering into the dark (ages) with low-frequency space interferometers: Using the 21-cm signal of neutral hydrogen from the infant universe to probe fundamental (Astro)physics.

Experimental astronomy

Koopmans LVE, Barkana R, Bentum M, Bernardi G, Boonstra AJ, Bowman J, Burns J, Chen X, Datta A, Falcke H, Fialkov A, Gehlot B, Gurvits L, Jelić V, Klein-Wolt M, Lazio J, Meerburg D, Mellema G, Mertens F, Mesinger A, Offringa A, Pritchard J, Semelin B, Subrahmanyan R, Silk J, Trott C, Vedantham H, Verde L, Zaroubi S, Zarka P.
PMID: 34511720
Exp Astron (Dordr). 2021 Sep 03;1-36. doi: 10.1007/s10686-021-09743-7. Epub 2021 Sep 03.

The Dark Ages and Cosmic Dawn are largely unexplored windows on the infant Universe (z ~ 200-10). Observations of the redshifted 21-cm line of neutral hydrogen can provide valuable new insight into fundamental physics and astrophysics during these eras...

Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits.

Frontiers in neuroanatomy

Datta D, Enwright JF, Arion D, Paspalas CD, Morozov YM, Lewis DA, Arnsten AFT.
PMID: 33328902
Front Neuroanat. 2020 Nov 20;14:578483. doi: 10.3389/fnana.2020.578483. eCollection 2020.

cAMP signaling has powerful, negative effects on cognitive functions of the primate dorsolateral prefrontal cortex (dlPFC), opening potassium channels to reduce firing and impair working memory, and increasing tau phosphorylation in aging neurons. This contrasts with cAMP actions in...

Unraveling City-Specific Microbial Signatures and Identifying Sample Origins for the Data From CAMDA 2020 Metagenomic Geolocation Challenge.

Frontiers in genetics

Zhang R, Ellis D, Walker AR, Datta S.
PMID: 34421984
Front Genet. 2021 Aug 05;12:659650. doi: 10.3389/fgene.2021.659650. eCollection 2021.

The composition of microbial communities has been known to be location-specific. Investigating the microbial composition across different cities enables us to unravel city-specific microbial signatures and further predict the origin of unknown samples. As part of the CAMDA 2020...

Microbial diversity and function in crystalline basement beneath the Deccan Traps explored in a 3 km borehole at Koyna, western India.

Environmental microbiology

Sahu RP, Kazy SK, Bose H, Mandal S, Dutta A, Saha A, Roy S, Dutta Gupta S, Mukherjee A, Sar P.
PMID: 34897962
Environ Microbiol. 2021 Dec 13; doi: 10.1111/1462-2920.15867. Epub 2021 Dec 13.

Deep terrestrial subsurface represents a huge repository of global prokaryotic biomass. Given its vastness and importance, microbial life within the deep subsurface continental crust remains under-represented in global studies. We characterize the microbial communities of deep, extreme and oligotrophic...

Effectiveness and feasibility of an evidence-based intraoperative infection control program targeting improved basic measures: a post-implementation prospective case-cohort study.

Journal of clinical anesthesia

Wall RT, Datta S, Dexter F, Ghyasi N, Robinson ADM, Persons D, Boling KA, McCloud CA, Krisanda EK, Gordon BM, Koff MD, Yeager MP, Brown J, Wong CA, Loftus RW.
PMID: 34929497
J Clin Anesth. 2021 Dec 17;77:110632. doi: 10.1016/j.jclinane.2021.110632. Epub 2021 Dec 17.

STUDY OBJECTIVE: A randomized controlled study demonstrated that an optimized intraoperative infection control program targeting basic preventive measures can reduce Staphylococcus aureus transmission and surgical site infections. In this study we address potential limitations of operating room heterogeneity of...

Interleukin-1 signaling in solid organ malignancies.

Biochimica et biophysica acta. Reviews on cancer

Dosch AR, Singh S, Nagathihalli NS, Datta J, Merchant NB.
PMID: 34923027
Biochim Biophys Acta Rev Cancer. 2021 Dec 16;1877(1):188670. doi: 10.1016/j.bbcan.2021.188670. Epub 2021 Dec 16.

As inflammation plays a critical role in the development and progression of cancer, therapeutic targeting of cytokine pathways involved in both tumorigenesis and dictating response to clinical treatments are of significant interest. Recent evidence has highlighted the importance of...

The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK.

Journal of cell science

Saha S, Zhang Y, Wilson B, Abounader R, Dutta A.
PMID: 34746949
J Cell Sci. 2021 Dec 15;134(24). doi: 10.1242/jcs.259306. Epub 2021 Dec 20.

Long noncoding RNAs (lncRNAs) are long RNA transcripts that do not code for proteins and have been shown to play a major role in cellular processes through diverse mechanisms. DRAIC, a lncRNA that is downregulated in castration-resistant advanced prostate...

Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.

Frontiers in aging neuroscience

Sevinc G, Rusche J, Wong B, Datta T, Kaufman R, Gutz SE, Schneider M, Todorova N, Gaser C, Thomalla G, Rentz D, Dickerson BD, Lazar SW.
PMID: 34512305
Front Aging Neurosci. 2021 Aug 27;13:702796. doi: 10.3389/fnagi.2021.702796. eCollection 2021.

Maintaining optimal cognitive functioning throughout the lifespan is a public health priority. Evaluation of cognitive outcomes following interventions to promote and preserve brain structure and function in older adults, and associated neural mechanisms, are therefore of critical importance. In...

Current Status of the Instructional Cues Provided by Notochordal Cells in Novel Disc Repair Strategies.

International journal of molecular sciences

Matta A, Erwin WM.
PMID: 35008853
Int J Mol Sci. 2021 Dec 31;23(1). doi: 10.3390/ijms23010427.

Numerous publications over the past 22 years, beginning with a seminal paper by Aguiar et al., have demonstrated the ability of notochordal cell-secreted factors to confer anabolic effects upon intervertebral disc (IVD) cells. Since this seminal paper, other scientific...

Hardware Design for Autonomous Bayesian Networks.

Frontiers in computational neuroscience

Faria R, Kaiser J, Camsari KY, Datta S.
PMID: 33762919
Front Comput Neurosci. 2021 Mar 08;15:584797. doi: 10.3389/fncom.2021.584797. eCollection 2021.

Directed acyclic graphs or Bayesian networks that are popular in many AI-related sectors for probabilistic inference and causal reasoning can be mapped to probabilistic circuits built out of probabilistic bits (p-bits), analogous to binary stochastic neurons of stochastic artificial...

A General Class of Signed Rank Tests for Clustered Data when the Cluster Size is Potentially Informative.

Journal of nonparametric statistics

Datta S, Nevalainen J, Oja H.
PMID: 23074359
J Nonparametr Stat. 2012 Sep 01;24(3):797-808. doi: 10.1080/10485252.2012.672647. Epub 2012 May 01.

Rank based tests are alternatives to likelihood based tests popularized by their relative robustness and underlying elegant mathematical theory. There has been a serge in research activities in this area in recent years since a number of researchers are...

Social-cognitive career theory predictors of STEM career interests and goal persistence in minority college students with disabilities: A path analysis.

Dutta A, Kang HJ, Kaya C, Benton SF, Sharp SE, Chan F, Cardoso EDS, Kundu M.
UIID-AD: 3630
2015;159-167. doi: 10.3233/JVR-150765.

OBJECTIVE: To test the Social-Cognitive Career Theory (SCCT) as a STEM career interests and goal persistence model for minority college students with disabilities. METHODS: A quantitative descriptive research design using path analysis. Participants included 115 minority college students with...

Showing 3169 to 3180 of 3180 entries