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Showing 25 to 36 of 167 entries
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Incidental cardiac findings on somatostatin receptor PET/CT: What do they indicate and are they of clinical relevance?.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Bobbio E, Dudás A, Bergström A, Esposito D, Angerås O, Taha A, van Essen M, Björkenstam M, Karason K, Bollano E, Bergh N, Polte CL.
PMID: 33502695
J Nucl Cardiol. 2021 Jan 27; doi: 10.1007/s12350-021-02526-9. Epub 2021 Jan 27.

We present the case of a 47-year-old man with a history of recurrent episodes of frontal headache, fever, and chest discomfort as well as longstanding, difficult to treat arterial hypertension. Clinical work-up revealed the unexpected finding of an underlying...

Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination.

Nature communications

Sharma VP, Tang B, Wang Y, Duran CL, Karagiannis GS, Xue EA, Entenberg D, Borriello L, Coste A, Eddy RJ, Kim G, Ye X, Jones JG, Grunblatt E, Agi N, Roy S, Bandyopadhyaya G, Adler E, Surve CR, Esposito D, Goswami S, Segall JE, Guo W, Condeelis JS, Wakefield LM, Oktay MH.
PMID: 34911937
Nat Commun. 2021 Dec 15;12(1):7300. doi: 10.1038/s41467-021-27308-2.

Cancer stem cells (CSCs) play an important role during metastasis, but the dynamic behavior and induction mechanisms of CSCs are not well understood. Here, we employ high-resolution intravital microscopy using a CSC biosensor to directly observe CSCs in live...

Editorial: Cosmeceuticals From Medicinal Plants.

Frontiers in pharmacology

Lall N, Mahomoodally MF, Esposito D, Steenkamp V, Zengin G, Steyn A, Oosthuizen CB.
PMID: 32848760
Front Pharmacol. 2020 Jul 29;11:1149. doi: 10.3389/fphar.2020.01149. eCollection 2020.

No abstract available.

Associations among locus coeruleus catecholamines, tau pathology, and memory in aging.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Ciampa CJ, Parent JH, Harrison TM, Fain RM, Betts MJ, Maass A, Winer JR, Baker SL, Janabi M, Furman DJ, D'Esposito M, Jagust WJ, Berry AS.
PMID: 35034099
Neuropsychopharmacology. 2022 Jan 15; doi: 10.1038/s41386-022-01269-6. Epub 2022 Jan 15.

The locus coeruleus (LC) is the brain's major source of the neuromodulator norepinephrine, and is also profoundly vulnerable to the development of Alzheimer's disease (AD)-related tau pathology. Norepinephrine plays a role in neuroprotective functions that may reduce AD progression,...

A betacoronavirus multiplex microsphere immunoassay detects early SARS-CoV-2 seroconversion and antibody cross reactions.

Research square

Laing E, Sterling S, Richard S, Epsi N, Phogat S, Samuels E, Yan L, Moreno N, Coles C, Drew M, Mehalko J, English C, Merritt S, Mende K, Chung K, Clifton G, Munster V, de Wit E, Tribble D, Agan B, Esposito D, Lanteri C, Mitre E, Burgess T, Broder C.
PMID: 33269345
Res Sq. 2020 Nov 24; doi: 10.21203/rs.3.rs-105768/v1.

Sensitive and specific SARS-CoV-2 antibody assays remain critical for community and hospital-based SARS-CoV-2 surveillance. Here, we developed and applied a multiplex microsphere-based immunoassay (MMIA) for COVD-19 antibody studies that incorporates spike protein trimers of SARS-CoV-2, SARS-CoV-1, MERS-CoV, and the...

Epicardial Adipose Tissue and IL-13 Response to Myocardial Injury Drives Left Ventricular Remodeling After ST Elevation Myocardial Infarction.

Frontiers in physiology

Parisi V, Cabaro S, D'Esposito V, Petraglia L, Conte M, Campana P, Gerundo G, Abitabile M, Tuccillo A, Accadia M, Comentale G, Pilato E, Sansone M, Leosco D, Formisano P.
PMID: 33178043
Front Physiol. 2020 Oct 15;11:575181. doi: 10.3389/fphys.2020.575181. eCollection 2020.

INTRODUCTION: Left ventricular (LV) remodeling after ST-segment elevation myocardial infarction (STEMI) is explained only in part by the infarct size, and the inter-patient variability may be ascribed to different inflammatory response to myocardial injury. Epicardial adipose tissue (EAT) is...

SARS-CoV-2 seroassay performance and optimization in a population with high background reactivity in Mali.

The Journal of infectious diseases

Woodford J, Sagara I, Dicko A, Zeguime A, Doucoure M, Kwan J, Zaidi I, Doritchamou J, Snow-Smith M, Alani N, Renn J, Kosik I, Holly J, Yewdell J, Esposito D, Sadtler K, Duffy P.
PMID: 34612499
J Infect Dis. 2021 Oct 06; doi: 10.1093/infdis/jiab498. Epub 2021 Oct 06.

BACKGROUND: False positivity may hinder the utility of SARS-CoV-2 serological tests in sub-Saharan Africa.METHODS: From 312 Malian samples collected prior to 2020, we measured antibodies to the commonly tested SARS-CoV-2 antigens and four other betacoronaviruses by ELISA. In a...

c-Src and EGFR Inhibition in Molecular Cancer Therapy: What Else Can We Improve?.

Cancers

Belli S, Esposito D, Servetto A, Pesapane A, Formisano L, Bianco R.
PMID: 32517369
Cancers (Basel). 2020 Jun 07;12(6). doi: 10.3390/cancers12061489.

The proto-oncogene c-Src is a non-receptor tyrosine kinase playing a key role in many cellular pathways, including cell survival, migration and proliferation. c-Src de-regulation has been observed in several cancer types, making it an appealing target for drug discovery...

Reading and writing difficultiesin third and sixth-grade students: a cross-sectional survey.

Minerva pediatrica

Operto FF, Esposito D, Nicoletti C, La Corte M, Del Duca R, Viggiano A, Pastorino GM, Aiello S, Malianni M, Coppola G.
PMID: 32508072
Minerva Pediatr. 2020 Jun 05; doi: 10.23736/S0026-4946.20.05619-4. Epub 2020 Jun 05.

BACKGROUND: In southern Italy and, specifically, in the region of Campania, many surveys show that the average of students with reading difficulties is much higher than in northern Italy and abroad. On the other hand, specific learning disorders (SLDs)...

SARS-CoV-2 seroassay optimization and performance in a population with high background reactivity in Mali.

medRxiv : the preprint server for health sciences

Sagara I, Woodford J, Dicko A, Zeguime A, Doucoure M, Kwan J, Zaidi I, Doritchamou J, Snow-Smith M, Alani N, Renn J, Kosik I, Holly J, Yewdell J, Esposito D, Sadtler K, Duffy P.
PMID: 33758883
medRxiv. 2021 Mar 12; doi: 10.1101/2021.03.08.21252784.

Serological tests are an indispensable tool to understand the epidemiology of the SARS-CoV-2 pandemic, particularly in areas where molecular diagnostics are limited. Poor assay performance may hinder the utility of these tests, including high rates of false-positivity previously reported...

Adipocyte-derived extracellular vesicles promote breast cancer cell malignancy through HIF-1α activity.

Cancer letters

La Camera G, Gelsomino L, Malivindi R, Barone I, Panza S, De Rose D, Giordano F, D'Esposito V, Formisano P, Bonofiglio D, Andò S, Giordano C, Catalano S.
PMID: 34425186
Cancer Lett. 2021 Aug 21;521:155-168. doi: 10.1016/j.canlet.2021.08.021. Epub 2021 Aug 21.

Extracellular vesicles (EVs) are emerging key protagonists in intercellular communication between adipocytes and breast cancer (BC) cells. Here, we described a new mechanism by which EVs released by mature adipocytes promoted breast cancer cell malignancy "in vitro" and "in...

SARS-CoV-2 Seroprevalence and Drug Use in Trauma Patients from Six Sites in the United States.

medRxiv : the preprint server for health sciences

Ngo TB, Karkanitsa M, Adusei KM, Graham LA, Ricotta EE, Darrah JR, Blomberg RD, Spathies J, Pauly KJ, Klumpp-Thomas C, Travers J, Mehalko J, Drew M, Hall MD, Memoli MJ, Esposito D, Kozar RA, Griggs C, Cunningham KW, Schulman CI, Crandall M, Neavyn M, Dorfman JD, Lai JT, Whitehill JM, Babu KM, Mohr NM, Van Heukelom J, Fell JC, Rooke W, Kalish H, Thomas FD, Sadtler K.
PMID: 34401892
medRxiv. 2021 Aug 11; doi: 10.1101/2021.08.10.21261849.

In comparison to the general patient population, trauma patients show higher level detections of bloodborne infectious diseases, such as Hepatitis and Human Immunodeficiency Virus. In comparison to bloodborne pathogens, the prevalence of respiratory infections such as SARS-CoV-2 and how...

Showing 25 to 36 of 167 entries