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Showing 25 to 36 of 232 entries
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Atmospheric forcing of rapid marine-terminating glacier retreat in the Canadian Arctic Archipelago.

Science advances

Cook AJ, Copland L, Noël BPY, Stokes CR, Bentley MJ, Sharp MJ, Bingham RG, van den Broeke MR.
PMID: 30891498
Sci Adv. 2019 Mar 13;5(3):eaau8507. doi: 10.1126/sciadv.aau8507. eCollection 2019 Mar.

The Canadian Arctic Archipelago contains >300 glaciers that terminate in the ocean, but little is known about changes in their frontal positions in response to recent changes in the ocean-climate system. Here, we examine changes in glacier frontal positions...

Characterization of the reference wave in a compact digital holographic camera.

Applied optics

Park IS, Middleton RJC, Coggrave CR, Ruiz PD, Coupland JM.
PMID: 29328151
Appl Opt. 2018 Jan 01;57(1):A235-A241. doi: 10.1364/AO.57.00A235.

A hologram is a recording of the interference between an unknown object wave and a coherent reference wave. Providing the object and reference waves are sufficiently separated in some region of space and the reference beam is known, a...

Evaluation of patient-reported outcome protocol content and reporting in UK cancer clinical trials: the EPiC study qualitative protocol.

BMJ open

Retzer A, Keeley T, Ahmed K, Armes J, Brown JM, Calman L, Copland C, Efficace F, Gavin A, Glaser A, Greenfield DM, Lanceley A, Taylor RM, Velikova G, Brundage M, Mercieca-Bebber R, King MT, Calvert M, Kyte D.
PMID: 29431123
BMJ Open. 2018 Feb 03;8(2):e017282. doi: 10.1136/bmjopen-2017-017282.

INTRODUCTION: Patient-reported outcomes (PROs) are increasingly included within cancer clinical trials. If appropriately collected, analysed and transparently reported, these data might provide invaluable evidence to inform patient care. However, there is mounting indication that the design and reporting of...

Women in Vision UK strive for gender equality in ophthalmology and vision sciences.

Therapeutic advances in ophthalmology

Khan H, Coupland SE, Moosajee M.
PMID: 29998223
Ther Adv Ophthalmol. 2018 Apr 26;10:2515841418774434. doi: 10.1177/2515841418774434. eCollection 2018.

No abstract available.

Substrates of speech treatment-induced neuroplasticity in adults and children with motor speech disorders: A systematic scoping review of neuroimaging evidence.

International journal of speech-language pathology

Whelan BM, Theodoros D, Mcmahon KL, Copland D, Aldridge D, Campbell J.
PMID: 34030526
Int J Speech Lang Pathol. 2021 Dec;23(6):579-592. doi: 10.1080/17549507.2021.1908425. Epub 2021 May 24.

No abstract available.

Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species.

Evolutionary bioinformatics online

Griswold CK.
PMID: 31723319
Evol Bioinform Online. 2019 Nov 05;15:1176934319883612. doi: 10.1177/1176934319883612. eCollection 2019.

In polymerase chain reaction (PCR)-based DNA sequencing studies, there is the possibility that mutations at the binding sites of primers result in no primer binding and therefore no amplification. In this article, we call such mutations PCR dropouts and...

A Systematic Review of Methods used to Conduct Decentralised Clinical Trials.

British journal of clinical pharmacology

Rogers A, De Paoli G, Subbarayan S, Copland R, Harwood K, Coyle J, Mitchell L, MacDonald TM, Mackenzie IS.
PMID: 34961991
Br J Clin Pharmacol. 2021 Dec 27; doi: 10.1111/bcp.15205. Epub 2021 Dec 27.

AIMS: To evaluate, using quantitative and qualitative approaches, published data on the design and conduct of decentralised clinical trials (DCTs).METHODS: We searched MEDLINE, EMBASE, CENTRAL, PsycINFO, ProQuest Dissertations and Theses, ClinicalTrials.gov, OpenGrey, and Google Scholar for publications reporting, discussing,...

Diagnostic uncertainty following orbital injury from a grease gun.

Orbit (Amsterdam, Netherlands)

Jawad M, Yamini K, Sultan Z, Coupland S, Hsuan J, McCormick A.
PMID: 34753381
Orbit. 2021 Nov 09;1-5. doi: 10.1080/01676830.2021.1992790. Epub 2021 Nov 09.

Orbital trauma involving high-pressure grease guns is rare and can cause significant morbidity due to retained intraorbital grease. Grease can appear similar to intraorbital air on cross-sectional imaging, and clinicians should have a high index of suspicion for retained...

XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma.

Gene therapy

Visuvanathan S, Baker AN, Lagali PS, Coupland SG, Miller G, Hauswirth WW, Tsilfidis C.
PMID: 34363035
Gene Ther. 2021 Aug 06; doi: 10.1038/s41434-021-00281-7. Epub 2021 Aug 06.

Glaucoma is a prevalent neurodegenerative disease that is characterized by progressive visual field loss. It is the leading cause of irreversible blindness in the world. The main risk factor for glaucoma is elevated intraocular pressure that results in the...

Unraveling the role of MADS transcription factor complexes in apple tree dormancy.

The New phytologist

da Silveira Falavigna V, Severing E, Lai X, Estevan J, Farrera I, Hugouvieux V, Revers LF, Zubieta C, Coupland G, Costes E, Andrés F, Thangasamy JR.
PMID: 34480759
New Phytol. 2021 Dec;232(5):2071-2088. doi: 10.1111/nph.17710. Epub 2021 Sep 23.

A group of MADS transcription factors (TFs) are believed to control temperature-mediated bud dormancy. These TFs, called DORMANCY-ASSOCIATED MADS-BOX (DAM), are encoded by genes similar to SHORT VEGETATIVE PHASE (SVP) from Arabidopsis. MADS proteins form transcriptional complexes whose combinatory...

Identifying symptoms associated with diagnosis of pancreatic exocrine and neuroendocrine neoplasms: a nested case-control study of the UK primary care population.

The British journal of general practice : the journal of the Royal College of General Practitioners

Liao W, Clift AK, Patone M, Coupland C, González-Izquierdo A, Pereira SP, Hippisley-Cox J.
PMID: 34544691
Br J Gen Pract. 2021 Oct 28;71(712):e836-e845. doi: 10.3399/BJGP.2021.0153. Print 2021 Nov.

BACKGROUND: Pancreatic cancer has the worst survival rate among all cancers. Almost 70% of patients in the UK were diagnosed at Stage IV.AIM: This study aimed to investigate the symptoms associated with the diagnoses of pancreatic ductal adenocarcinoma (PDAC)...

EPA and DHA containing phospholipids have contrasting effects on membrane structure.

Journal of lipid research

Sherratt SCR, Juliano RA, Copland C, Bhatt DL, Libby P, Mason RP.
PMID: 34400132
J Lipid Res. 2021;62:100106. doi: 10.1016/j.jlr.2021.100106. Epub 2021 Aug 13.

Omega-3 FAs EPA and DHA influence membrane fluidity, lipid rafts, and signal transduction. A clinical trial, Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial, demonstrated that high-dose EPA (4 g/d icosapent ethyl) reduced composite cardiovascular events in statin-treated high-risk...

Showing 25 to 36 of 232 entries