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Showing 217 to 226 of 226 entries
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Herpesvirus DNA polymerase: Structures, functions, and mechanisms.

The Enzymes

Coen DM, Lawler JL, Abraham J.
PMID: 34861935
Enzymes. 2021;50:133-178. doi: 10.1016/bs.enz.2021.09.003. Epub 2021 Nov 02.

Herpesviruses comprise a family of DNA viruses that cause a variety of human and veterinary diseases. During productive infection, mammalian, avian, and reptilian herpesviruses replicate their genomes using a set of conserved viral proteins that include a two subunit...

Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system.

ACS chemical neuroscience

Lebois EP, Bridges TM, Lewis LM, Dawson ES, Kane AS, Xiang Z, Jadhav SB, Yin H, Kennedy JP, Meiler J, Niswender CM, Jones CK, Conn PJ, Weaver CD, Lindsley CW.
PMID: 21961051
ACS Chem Neurosci. 2010;1(2):104-121. doi: 10.1021/cn900003h.

Cholinergic transmission in the forebrain is mediated primarily by five subtypes of muscarinic acetylcholine receptors (mAChRs), termed M(1)-M(5). Of the mAChR subtypes, M(1) is among the most heavily expressed in regions that are critical for learning and memory, and...

Pregnant Smokers' Intention to Switch From Cigarettes to E-Cigarettes: A Reasoned Action Approach.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Dobbs PD, Branscum P, Cohn AM, Tackett AP, Comiford AL.
PMID: 34452825
Womens Health Issues. 2021 Nov-Dec;31(6):540-549. doi: 10.1016/j.whi.2021.07.005. Epub 2021 Aug 25.

INTRODUCTION: This study used the reasoned action approach (RAA) to examine 1) factors associated with pregnant smokers' intention to switch from cigarettes to e-cigarettes and 2) the influence that intention to switch had on future expectations to resume cigarette...

Corrigendum to "Correlates of e-cigarette use among adults initiating smoking cessation treatment" [Drug Alcohol Depend. 224 (2021) 108724].

Drug and alcohol dependence

Boozary LK, Frank-Pearce SG, Alexander AC, Waring JJC, Ehlke SJ, Businelle MS, Cohn AM, Kendzor DE.
PMID: 34583106
Drug Alcohol Depend. 2021 Nov 01;228:109035. doi: 10.1016/j.drugalcdep.2021.109035. Epub 2021 Sep 25.

No abstract available.

Internalizing problems are associated with initiation and past 30-Day use of flavored tobacco products.

Addictive behaviors

Ganz O, Cohn AM, Goodwin RD, Giovenco DP, Wackowski OA, Talbot EM, Delnevo CD.
PMID: 34763300
Addict Behav. 2022 Feb;125:107162. doi: 10.1016/j.addbeh.2021.107162. Epub 2021 Oct 26.

OBJECTIVE: Tobacco use remains disproportionately common among adults with internalizing problems. The rising prevalence of flavored tobacco use among this population may be a contributing factor. Using data from Wave 4 of the Population Assessment of Tobacco and Health...

Simulation-Based Training Improves Fellows' Competence in Brain Death Discussion and Declaration.

The neurologist

Chen PM, Trando A, LaBuzetta JN.
PMID: 34842565
Neurologist. 2021 Nov 26;27(1):6-10. doi: 10.1097/NRL.0000000000000354.

BACKGROUND: Despite well-defined American Academy of Neurology guidelines for death by whole brain criteria (brain death), there is marked variability in national practice, which some have attributed to lack of formal education. Further, communication with surrogates and families about...

Finding MyVOICE: A Mixed-Methods Examination of Health Outcomes of Young Adults with Chronic Illness Transitioning from Pediatric to Adult Health Care.

Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners

Wright S, Conn BM, Shahinian M, Keyllian C, Tanaka D, Iverson E.
PMID: 34325977
J Pediatr Health Care. 2021 Nov-Dec;35(6):610-620. doi: 10.1016/j.pedhc.2021.06.002. Epub 2021 Jul 27.

INTRODUCTION: This study examines health use outcomes of young adults with chronic illness following participation in a transition program and identifies variables that impact outcomes.METHOD: A sample of 119 ethnically diverse, low-income young adults (mean age = 21.8 years)...

Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses.

Cell

Cui C, Wang J, Fagerberg E, Chen PM, Connolly KA, Damo M, Cheung JF, Mao T, Askari AS, Chen S, Fitzgerald B, Foster GG, Eisenbarth SC, Zhao H, Craft J, Joshi NS.
PMID: 34852236
Cell. 2021 Dec 09;184(25):6101-6118.e13. doi: 10.1016/j.cell.2021.11.007. Epub 2021 Nov 30.

CD4 T follicular helper (TFH) cells support B cells, which are critical for germinal center (GC) formation, but the importance of TFH-B cell interactions in cancer is unclear. We found enrichment of TFH cell transcriptional signature correlates with GC...

Predictors of nonsentinel nodal involvement to aid intraoperative decision making in breast cancer patients with positive sentinel lymph nodes.

ISRN oncology

Tan EY, Ho B, Chen JJ, Ho PW, Teo C, Earnest A, Chan PM.
PMID: 22091423
ISRN Oncol. 2011;2011:539503. doi: 10.5402/2011/539503. Epub 2011 Aug 16.

Background. Up to 60% of patients with a positive sentinel lymph node (SLN) have no additional nodal involvement and do not benefit from completion axillary lymph node dissection (ALND). We aim to identify factors predicting for non-SLN involvement and...

Comparison of Anticoagulation Regimens Following Stent Placement for Nonthrombotic Lower Extremity Venous Disease.

Journal of vascular and interventional radiology : JVIR

Arendt VA, Mabud TS, Kuo WT, Jeon GS, An X, Cohn DM, Fu JX, Hofmann LV.
PMID: 34478851
J Vasc Interv Radiol. 2021 Nov;32(11):1584-1590. doi: 10.1016/j.jvir.2021.08.016. Epub 2021 Aug 31.

PURPOSE: To determine whether subtherapeutic anticoagulation regimens are noninferior to therapeutic anticoagulation regimens following stent placement for nonthrombotic lower extremity venous disease.MATERIALS AND METHODS: Fifty-one consecutive patients (88% women; mean age, 44 years) who underwent stent placement for nonthrombotic...

Showing 217 to 226 of 226 entries