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Showing 865 to 876 of 876 entries
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Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial.

EClinicalMedicine

Chan EW, Lao KSJ, Lam L, Tsui SH, Lui CT, Wong CP, Graham CA, Cheng CH, Chung TS, Lam HF, Ting SM, Knott JC, Taylor DM, Kong DCM, Leung LP, Wong ICK.
PMID: 33681744
EClinicalMedicine. 2021 Feb 11;32:100751. doi: 10.1016/j.eclinm.2021.100751. eCollection 2021 Feb.

BACKGROUND: The safety and effectiveness of intramuscular olanzapine or haloperidol compared to midazolam as the initial pharmacological treatment for acute agitation in emergency departments (EDs) has not been evaluated.METHODS: A pragmatic, randomised, double-blind, active-controlled trial was conducted from December...

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Chan EW, Lao KSJ, Lam L, et al. Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial. EClinicalMedicine. 2021;32:100751doi: 10.1016/j.eclinm.2021.100751.
Chan, E. W., Lao, K. S. J., Lam, L., Tsui, S. H., Lui, C. T., Wong, C. P., Graham, C. A., Cheng, C. H., Chung, T. S., Lam, H. F., Ting, S. M., Knott, J. C., Taylor, D. M., Kong, D. C. M., Leung, L. P., & Wong, I. C. K. (2021). Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial. EClinicalMedicine, 32100751. https://doi.org/10.1016/j.eclinm.2021.100751
Chan, Esther W, et al. "Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial." EClinicalMedicine vol. 32 (2021): 100751. doi: https://doi.org/10.1016/j.eclinm.2021.100751
Chan EW, Lao KSJ, Lam L, Tsui SH, Lui CT, Wong CP, Graham CA, Cheng CH, Chung TS, Lam HF, Ting SM, Knott JC, Taylor DM, Kong DCM, Leung LP, Wong ICK. Intramuscular midazolam, olanzapine, or haloperidol for the management of acute agitation: A multi-centre, double-blind, randomised clinical trial. EClinicalMedicine. 2021 Feb 11;32:100751. doi: 10.1016/j.eclinm.2021.100751. eCollection 2021 Feb. PMID: 33681744; PMCID: PMC7910711.
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Circulating Cell-Free Mitochondrial DNA in Cerebrospinal Fluid as a Biomarker for Mitochondrial Diseases.

Clinical chemistry

Trifunov S, Paredes-Fuentes AJ, Badosa C, Codina A, Montoya J, Ruiz-Pesini E, Jou C, Garrabou G, Grau-Junyent JM, Yubero D, Montero R, Muchart J, Ortigoza-Escobar JD, O'Callaghan MM, Nascimento A, Català A, Garcia-Cazorla À, Jimenez-Mallebrera C, Artuch R.
PMID: 34352085
Clin Chem. 2021 Aug 05;67(8):1113-1121. doi: 10.1093/clinchem/hvab091.

BACKGROUND: Mitochondrial diseases (MD) are genetic metabolic disorders that impair normal mitochondrial structure or function. The aim of this study was to investigate the status of circulating cell-free mitochondrial DNA (ccfmtDNA) in cerebrospinal fluid (CSF), together with other biomarkers...

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Trifunov S, Paredes-Fuentes AJ, Badosa C, et al. Circulating Cell-Free Mitochondrial DNA in Cerebrospinal Fluid as a Biomarker for Mitochondrial Diseases. Clin Chem. 2021;67(8):1113-1121doi: 10.1093/clinchem/hvab091.
Trifunov, S., Paredes-Fuentes, A. J., Badosa, C., Codina, A., Montoya, J., Ruiz-Pesini, E., Jou, C., Garrabou, G., Grau-Junyent, J. M., Yubero, D., Montero, R., Muchart, J., Ortigoza-Escobar, J. D., O'Callaghan, M. M., Nascimento, A., Català, A., Garcia-Cazorla, �. �., Jimenez-Mallebrera, C., & Artuch, R. (2021). Circulating Cell-Free Mitochondrial DNA in Cerebrospinal Fluid as a Biomarker for Mitochondrial Diseases. Clinical chemistry, 67(8), 1113-1121. https://doi.org/10.1093/clinchem/hvab091
Trifunov, Selena, et al. "Circulating Cell-Free Mitochondrial DNA in Cerebrospinal Fluid as a Biomarker for Mitochondrial Diseases." Clinical chemistry vol. 67,8 (2021): 1113-1121. doi: https://doi.org/10.1093/clinchem/hvab091
Trifunov S, Paredes-Fuentes AJ, Badosa C, Codina A, Montoya J, Ruiz-Pesini E, Jou C, Garrabou G, Grau-Junyent JM, Yubero D, Montero R, Muchart J, Ortigoza-Escobar JD, O'Callaghan MM, Nascimento A, Català A, Garcia-Cazorla À, Jimenez-Mallebrera C, Artuch R. Circulating Cell-Free Mitochondrial DNA in Cerebrospinal Fluid as a Biomarker for Mitochondrial Diseases. Clin Chem. 2021 Aug 05;67(8):1113-1121. doi: 10.1093/clinchem/hvab091. PMID: 34352085.
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Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age.

Age and ageing

Olde Rikkert MGM, Melis RJF, Cohen AA, Geeske Peeters GMEE.
PMID: 35018409
Age Ageing. 2022 Jan 10; doi: 10.1093/ageing/afab267. Epub 2022 Jan 10.

Clinical reasoning and research in modern geriatrics often prioritises the disease concept. This is understandable as it has brought impressive advances in medicine (e.g. antibiotics, vaccines, successful cancer treatment and many effective surgeries). However, so far the disease framework...

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Olde Rikkert MGM, Melis RJF, Cohen AA, et al. Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age. Age Ageing. 2022;doi: 10.1093/ageing/afab267.
Olde Rikkert, M. G. M., Melis, R. J. F., Cohen, A. A., & Geeske Peeters, G. M. E. E. (2022). Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age. Age and ageing, . https://doi.org/10.1093/ageing/afab267
Olde Rikkert, Marcel G M, et al. "Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age." Age and ageing vol. (2022). doi: https://doi.org/10.1093/ageing/afab267
Olde Rikkert MGM, Melis RJF, Cohen AA, Geeske Peeters GMEE. Age and Ageing journal 50th anniversary commentary seriesWhy illness is more important than disease in old age. Age Ageing. 2022 Jan 10; doi: 10.1093/ageing/afab267. Epub 2022 Jan 10. PMID: 35018409.
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Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants.

Pediatric pulmonology

Szabó H, Baraldi E, Colin AA.
PMID: 34964564
Pediatr Pulmonol. 2021 Dec 29; doi: 10.1002/ppul.25808. Epub 2021 Dec 29.

This paper is the second in a two-part State-of-the-Art series that reviews the latest relevant clinical trials investigating the short-term and long-term effects of corticosteroids in the prevention and treatment of bronchopulmonary dysplasia (BPD). Inhaled postnatal corticosteroids demonstrate low...

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Szabó H, Baraldi E, Colin AA. Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants. Pediatr Pulmonol. 2021;doi: 10.1002/ppul.25808.
Szabó, H., Baraldi, E., & Colin, A. A. (2021). Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants. Pediatric pulmonology, . https://doi.org/10.1002/ppul.25808
Szabó, Hajnalka, et al. "Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants." Pediatric pulmonology vol. (2021). doi: https://doi.org/10.1002/ppul.25808
Szabó H, Baraldi E, Colin AA. Corticosteroids in the prevention and treatment of infants with bronchopulmonary dysplasia: Part II. Inhaled corticosteroids alone or in combination with surfactants. Pediatr Pulmonol. 2021 Dec 29; doi: 10.1002/ppul.25808. Epub 2021 Dec 29. PMID: 34964564.
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Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes.

Neuroepidemiology

Wijeratne T, Kuan WS, Kelly AM, Chu KH, Kinnear FB, Keijzers G, Body R, Karamercan MA, Klim S, Kamona S, Graham CA, Roberts T, Horner D, Laribi S.
PMID: 35021181
Neuroepidemiology. 2022 Jan 12;1-9. doi: 10.1159/000520548. Epub 2022 Jan 12.

BACKGROUND AND AIM: Migraine headache is commonly diagnosed in emergency departments (ED). There is relatively little real-world information about the epidemiology, investigation, management, adherence to therapeutic guidelines and disposition of patients treated in ED with a final diagnosis of...

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Wijeratne T, Kuan WS, Kelly AM, et al. Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes. Neuroepidemiology. 2022;1-9doi: 10.1159/000520548.
Wijeratne, T., Kuan, W. S., Kelly, A. M., Chu, K. H., Kinnear, F. B., Keijzers, G., Body, R., Karamercan, M. A., Klim, S., Kamona, S., Graham, C. A., Roberts, T., Horner, D., Laribi, S. (2022). Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes. Neuroepidemiology, 1-9. https://doi.org/10.1159/000520548
Wijeratne, Tissa, et al. "Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes." Neuroepidemiology vol. (2022): 1-9. doi: https://doi.org/10.1159/000520548
Wijeratne T, Kuan WS, Kelly AM, Chu KH, Kinnear FB, Keijzers G, Body R, Karamercan MA, Klim S, Kamona S, Graham CA, Roberts T, Horner D, Laribi S. Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes. Neuroepidemiology. 2022 Jan 12;1-9. doi: 10.1159/000520548. Epub 2022 Jan 12. PMID: 35021181.
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Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue.

Cancers

Terreri S, Mancinelli S, Ferro M, Vitale MC, Perdonà S, Castaldo L, Gigantino V, Mercadante V, De Cecio R, Aquino G, Montella M, Angelini C, Del Prete E, Aprile M, Ciaramella A, Liguori GL, Costa V, Calin GA, La Civita E, Terracciano D, Febbraio F, Cimmino A.
PMID: 33567603
Cancers (Basel). 2021 Feb 08;13(4). doi: 10.3390/cancers13040681.

Non-coding RNA transcripts originating from Ultraconserved Regions (UCRs) have tissue-specific expression and play relevant roles in the pathophysiology of multiple cancer types. Among them, we recently identified and characterized the ultra-conserved-transcript-8+ (uc.8+), whose levels correlate with grading and staging...

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Terreri S, Mancinelli S, Ferro M, et al. Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue. Cancers (Basel). 2021;13(4)doi: 10.3390/cancers13040681.
Terreri, S., Mancinelli, S., Ferro, M., Vitale, M. C., Perdonà, S., Castaldo, L., Gigantino, V., Mercadante, V., De Cecio, R., Aquino, G., Montella, M., Angelini, C., Del Prete, E., Aprile, M., Ciaramella, A., Liguori, G. L., Costa, V., Calin, G. A., La Civita, E., Terracciano, D., Febbraio, F., & Cimmino, A. (2021). Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue. Cancers, 13(4), . https://doi.org/10.3390/cancers13040681
Terreri, Sara, et al. "Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue." Cancers vol. 13,4 (2021). doi: https://doi.org/10.3390/cancers13040681
Terreri S, Mancinelli S, Ferro M, Vitale MC, Perdonà S, Castaldo L, Gigantino V, Mercadante V, De Cecio R, Aquino G, Montella M, Angelini C, Del Prete E, Aprile M, Ciaramella A, Liguori GL, Costa V, Calin GA, La Civita E, Terracciano D, Febbraio F, Cimmino A. Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue. Cancers (Basel). 2021 Feb 08;13(4). doi: 10.3390/cancers13040681. PMID: 33567603; PMCID: PMC7914980.
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Low levels of .

iScience

Girona-Alarcon M, Argüello G, Esteve-Sole A, Bobillo-Perez S, Paolo-Burgos X, Bonet-Carne E, Mensa-Vilaró A, Codina A, Hernández-Garcia M, Jou C, Alsina L, Jordan I.
PMID: 34904133
iScience. 2021 Dec 09;103595. doi: 10.1016/j.isci.2021.103595. Epub 2021 Dec 09.

It is unclear why COVID-19 ranges from asymptomatic to severe. When SARS-CoV-2 is detected, interferon (IFN) response is activated. When it is insufficient or delayed, it might lead to overproduction of cytokines and severe COVID-19. The aim was to...

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Girona-Alarcon M, Argüello G, Esteve-Sole A, et al. Low levels of . iScience. 2021;103595doi: 10.1016/j.isci.2021.103595.
Girona-Alarcon, M., Argüello, G., Esteve-Sole, A., Bobillo-Perez, S., Paolo-Burgos, X., Bonet-Carne, E., Mensa-Vilaró, A., Codina, A., Hernández-Garcia, M., Jou, C., Alsina, L., & Jordan, I. (2021). Low levels of . iScience, 103595. https://doi.org/10.1016/j.isci.2021.103595
Girona-Alarcon, Mònica, et al. "Low levels of ." iScience vol. (2021): 103595. doi: https://doi.org/10.1016/j.isci.2021.103595
Girona-Alarcon M, Argüello G, Esteve-Sole A, Bobillo-Perez S, Paolo-Burgos X, Bonet-Carne E, Mensa-Vilaró A, Codina A, Hernández-Garcia M, Jou C, Alsina L, Jordan I. Low levels of . iScience. 2021 Dec 09;103595. doi: 10.1016/j.isci.2021.103595. Epub 2021 Dec 09. PMID: 34904133; PMCID: PMC8654705.
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Independent evaluation of 12 artificial intelligence solutions for the detection of tuberculosis.

Scientific reports

Codlin AJ, Dao TP, Vo LNQ, Forse RJ, Van Truong V, Dang HM, Nguyen LH, Nguyen HB, Nguyen NV, Sidney-Annerstedt K, Squire B, Lönnroth K, Caws M.
PMID: 34903808
Sci Rep. 2021 Dec 13;11(1):23895. doi: 10.1038/s41598-021-03265-0.

There have been few independent evaluations of computer-aided detection (CAD) software for tuberculosis (TB) screening, despite the rapidly expanding array of available CAD solutions. We developed a test library of chest X-ray (CXR) images which was blindly re-read by...

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Codlin AJ, Dao TP, Vo LNQ, et al. Independent evaluation of 12 artificial intelligence solutions for the detection of tuberculosis. Sci Rep. 2021;11(1):23895doi: 10.1038/s41598-021-03265-0.
Codlin, A. J., Dao, T. P., Vo, L. N. Q., Forse, R. J., Van Truong, V., Dang, H. M., Nguyen, L. H., Nguyen, H. B., Nguyen, N. V., Sidney-Annerstedt, K., Squire, B., Lönnroth, K., & Caws, M. (2021). Independent evaluation of 12 artificial intelligence solutions for the detection of tuberculosis. Scientific reports, 11(1), 23895. https://doi.org/10.1038/s41598-021-03265-0
Codlin, Andrew J, et al. "Independent evaluation of 12 artificial intelligence solutions for the detection of tuberculosis." Scientific reports vol. 11,1 (2021): 23895. doi: https://doi.org/10.1038/s41598-021-03265-0
Codlin AJ, Dao TP, Vo LNQ, Forse RJ, Van Truong V, Dang HM, Nguyen LH, Nguyen HB, Nguyen NV, Sidney-Annerstedt K, Squire B, Lönnroth K, Caws M. Independent evaluation of 12 artificial intelligence solutions for the detection of tuberculosis. Sci Rep. 2021 Dec 13;11(1):23895. doi: 10.1038/s41598-021-03265-0. PMID: 34903808; PMCID: PMC8668935.
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Housing Repair and Crime-Investment at a Small Scale for a Potential Big Impact.

JAMA network open

Tillyer MS, Walter RJ, Acolin A.
PMID: 34287635
JAMA Netw Open. 2021 Jul 01;4(7):e2117624. doi: 10.1001/jamanetworkopen.2021.17624.

No abstract available.

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Tillyer MS, Walter RJ, Acolin A. Housing Repair and Crime-Investment at a Small Scale for a Potential Big Impact. JAMA Netw Open. 2021;4(7):e2117624doi: 10.1001/jamanetworkopen.2021.17624.
Tillyer, M. S., Walter, R. J., & Acolin, A. (2021). Housing Repair and Crime-Investment at a Small Scale for a Potential Big Impact. JAMA network open, 4(7), e2117624. https://doi.org/10.1001/jamanetworkopen.2021.17624
Tillyer, Marie Skubak, et al. "Housing Repair and Crime-Investment at a Small Scale for a Potential Big Impact." JAMA network open vol. 4,7 (2021): e2117624. doi: https://doi.org/10.1001/jamanetworkopen.2021.17624
Tillyer MS, Walter RJ, Acolin A. Housing Repair and Crime-Investment at a Small Scale for a Potential Big Impact. JAMA Netw Open. 2021 Jul 01;4(7):e2117624. doi: 10.1001/jamanetworkopen.2021.17624. PMID: 34287635.
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Comparing Small Area Fair Market Rents With Other Rental Measures Across Diverse Housing Markets.

Cityscape (Washington, D.C.)

Hess C, Walter RJ, Acolin A, Chasins S.
PMID: 33889226
Cityscape. 2019;21(3):159-186.

Small Area Fair Market Rents (SAFMRs) are calculated at the 40th percentile of the U.S. postal ZIP Code instead of the metropolitan area in an effort to capture localized rents to expand choice for voucher holders to access housing...

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Hess C, Walter RJ, Acolin A, et al. Comparing Small Area Fair Market Rents With Other Rental Measures Across Diverse Housing Markets. Cityscape. 2019;21(3):159-186
Hess, C., Walter, R. J., Acolin, A., & Chasins, S. (2019). Comparing Small Area Fair Market Rents With Other Rental Measures Across Diverse Housing Markets. Cityscape (Washington, D.C.), 21(3), 159-186.
Hess, Christian, et al. "Comparing Small Area Fair Market Rents With Other Rental Measures Across Diverse Housing Markets." Cityscape (Washington, D.C.) vol. 21,3 (2019): 159-186.
Hess C, Walter RJ, Acolin A, Chasins S. Comparing Small Area Fair Market Rents With Other Rental Measures Across Diverse Housing Markets. Cityscape. 2019;21(3):159-186. PMID: 33889226; PMCID: PMC8059671.
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Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials.

Neuroscience and biobehavioral reviews

Bisdounis L, Saunders KEA, Farley HJ, Lee CK, McGowan NM, Espie CA, Kyle SD.
PMID: 34871635
Neurosci Biobehav Rev. 2021 Dec 03; doi: 10.1016/j.neubiorev.2021.12.002. Epub 2021 Dec 03.

Sleep and circadian disruptions are prominent symptoms of bipolar disorder (BD) and potential targets for adjunctive interventions. The aim of this review was to appraise the effectiveness of psychological and behavioural interventions in BD that target sleep and circadian...

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Bisdounis L, Saunders KEA, Farley HJ, et al. Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials. Neurosci Biobehav Rev. 2021;doi: 10.1016/j.neubiorev.2021.12.002.
Bisdounis, L., Saunders, K. E. A., Farley, H. J., Lee, C. K., McGowan, N. M., Espie, C. A., & Kyle, S. D. (2021). Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials. Neuroscience and biobehavioral reviews, . https://doi.org/10.1016/j.neubiorev.2021.12.002
Bisdounis, Lampros, et al. "Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials." Neuroscience and biobehavioral reviews vol. (2021). doi: https://doi.org/10.1016/j.neubiorev.2021.12.002
Bisdounis L, Saunders KEA, Farley HJ, Lee CK, McGowan NM, Espie CA, Kyle SD. Psychological and behavioural interventions in bipolar disorder that target sleep and circadian rhythms: a systematic review of randomised controlled trials. Neurosci Biobehav Rev. 2021 Dec 03; doi: 10.1016/j.neubiorev.2021.12.002. Epub 2021 Dec 03. PMID: 34871635.
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Serotonin system genes contribute to the susceptibility to obesity in Black adolescents.

Obesity science & practice

Meng Y, Groth SW, Hodgkinson CA, Mariani TJ.
PMID: 34401202
Obes Sci Pract. 2021 Mar 27;7(4):441-449. doi: 10.1002/osp4.511. eCollection 2021 Aug.

OBJECTIVE: The importance of the central and peripheral serotonin systems in regulating energy balance and obesity development has been highlighted in animal models. Yet, the role of both serotonin systems has not been systematically assessed in humans. The purpose...

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Meng Y, Groth SW, Hodgkinson CA, et al. Serotonin system genes contribute to the susceptibility to obesity in Black adolescents. Obes Sci Pract. 2021;7(4):441-449doi: 10.1002/osp4.511.
Meng, Y., Groth, S. W., Hodgkinson, C. A., & Mariani, T. J. (2021). Serotonin system genes contribute to the susceptibility to obesity in Black adolescents. Obesity science & practice, 7(4), 441-449. https://doi.org/10.1002/osp4.511
Meng, Ying, et al. "Serotonin system genes contribute to the susceptibility to obesity in Black adolescents." Obesity science & practice vol. 7,4 (2021): 441-449. doi: https://doi.org/10.1002/osp4.511
Meng Y, Groth SW, Hodgkinson CA, Mariani TJ. Serotonin system genes contribute to the susceptibility to obesity in Black adolescents. Obes Sci Pract. 2021 Mar 27;7(4):441-449. doi: 10.1002/osp4.511. eCollection 2021 Aug. PMID: 34401202; PMCID: PMC8346375.
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