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Showing 697 to 704 of 704 entries
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KFP-1, a Novel Calcium-Binding Peptide Isolated from Kefir, Promotes Calcium Influx Through TRPV6 Channels.

Molecular nutrition & food research

Chang GR, Tu MY, Chen YH, Chang KY, Chen CF, Lai JC, Tung YT, Chen HL, Fan HC, Chen CM.
PMID: 34477300
Mol Nutr Food Res. 2021 Nov;65(22):e2100182. doi: 10.1002/mnfr.202100182. Epub 2021 Oct 19.

INTRODUCTION: Kefir is an acidic and alcoholic fermented milk product with multiple health-promoting benefits. A previous study demonstrated that kefir enhanced calcium absorption in intestinal Caco-2 cells. In this study, kefir-fermented peptide-1 (KFP-1) is isolated from the kefir peptide...

Comparison of Anticoagulation Regimens Following Stent Placement for Nonthrombotic Lower Extremity Venous Disease.

Journal of vascular and interventional radiology : JVIR

Arendt VA, Mabud TS, Kuo WT, Jeon GS, An X, Cohn DM, Fu JX, Hofmann LV.
PMID: 34478851
J Vasc Interv Radiol. 2021 Nov;32(11):1584-1590. doi: 10.1016/j.jvir.2021.08.016. Epub 2021 Aug 31.

PURPOSE: To determine whether subtherapeutic anticoagulation regimens are noninferior to therapeutic anticoagulation regimens following stent placement for nonthrombotic lower extremity venous disease.MATERIALS AND METHODS: Fifty-one consecutive patients (88% women; mean age, 44 years) who underwent stent placement for nonthrombotic...

Predictive Role of Prior Radiotherapy and Immunotherapy-Related Adverse Effects in Advanced NSCLC Patients Receiving Anti-PD-1/L1 Therapy.

Journal of clinical medicine

Lim JU, Kim SH, Kang HS, Kim SK, Kim JS, Kim JW, Kim SJ, Yeo CD, Choi CM.
PMID: 34442015
J Clin Med. 2021 Aug 21;10(16). doi: 10.3390/jcm10163719.

The present study evaluated the impact of prior radiotherapy (RT) on patients with advanced non-small cell lung cancer (NSCLC) receiving therapy with immune checkpoint inhibitors (ICIs) and further assessed the prognostic factors in patients receiving both RT and ICI....

Malignancy in giant cell tumor of bone in the extremities.

Journal of bone oncology

Liu W, Chan CM, Gong L, Bui MM, Han G, Letson GD, Yang Y, Niu X.
PMID: 33251099
J Bone Oncol. 2020 Nov 05;26:100334. doi: 10.1016/j.jbo.2020.100334. eCollection 2021 Feb.

BACKGROUND: Malignancy in giant cell tumor of bone (GCTB) is a rare tumor with relevant literature being sparse. In primary malignant GCTB, distinct areas of benign GCTB are juxtaposed with high-grade sarcoma, while in secondary malignant GCTB sarcoma occurs...

Improving Algorithm for the Alignment of Consecutive, Whole-Slide, Immunohistochemical Section Images.

Journal of pathology informatics

Liang CW, Chang RF, Fang PW, Chen CM.
PMID: 34476109
J Pathol Inform. 2021 Aug 03;12:29. doi: 10.4103/jpi.jpi_106_20. eCollection 2021.

BACKGROUND: Accurate and precise alignment of histopathology tissue sections is a key step for the interpretation of the proteome topology and cell level three-dimensional (3D) reconstruction of diseased tissues. However, the realization of an automated and robust method for...

OPTICAL COHERENCE TOMOGRAPHY FEATURES OF POLYPOIDAL LESION CLOSURE IN POLYPOIDAL CHOROIDAL VASCULOPATHY TREATED WITH AFLIBERCEPT.

Retina (Philadelphia, Pa.)

Tan ACS, Jordan-Yu JM, Vyas CH, Gan ATL, Teo KYC, Chan CM, Mathur R, Wong TY, Chakravarthy U, Cheung GCM.
PMID: 34412103
Retina. 2022 Jan 01;42(1):114-122. doi: 10.1097/IAE.0000000000003285.

PURPOSE: To evaluate whether optical coherence tomography (OCT) can determine polypoidal lesion (PL) perfusion in polypoidal choroidal vasculopathy eyes after 12 months of aflibercept monotherapy. Polypoidal lesion perfusion status, assessed by indocyanine green angiography, is an important anatomical outcome...

GPR120 Inhibits Colitis Through Regulation of CD4.

Gastroenterology

Yang W, Liu H, Xu L, Yu T, Zhao X, Yao S, Zhao Q, Barnes S, Cohn SM, Dann SM, Zhang H, Zuo X, Li Y, Cong Y.
PMID: 34536451
Gastroenterology. 2022 Jan;162(1):150-165. doi: 10.1053/j.gastro.2021.09.018. Epub 2021 Sep 16.

BACKGROUND & AIMS: G protein-coupled receptor (GPR) 120 has been implicated in regulating metabolic syndromes with anti-inflammatory function. However, the role of GPR120 in intestinal inflammation is unknown. Here, we investigated whether and how GPR120 regulates CD4METHODS: Dextran sodium...

How can we improve clinical research in clinical practice with better research outcome?.

Woo KT, Wong KS, Lee EJ, Chan CM.
UIID-AD: 2922
2011;40:499-506.

This paper explains some of the difficulties doctors face when taking up a career in research. It describes the efforts by the government and the Ministry of Health (MOH) to nurture the Clinician Scientist Programme. The nature of research...

Showing 697 to 704 of 704 entries