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Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2.

Journal of molecular biology

Meissner ME, Willkomm NA, Lucas J, Arndt WG, Aitken SF, Julik EJ, Baliga S, Mansky LM.
PMID: 34774569
J Mol Biol. 2021 Nov 10;434(2):167355. doi: 10.1016/j.jmb.2021.167355. Epub 2021 Nov 10.

Human immunodeficiency virus (HIV) mutagenesis is driven by a variety of internal and external sources, including the host APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypetide-like 3; A3) family of mutagenesis factors, which catalyze G-to-A transition mutations during virus...

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Meissner ME, Willkomm NA, Lucas J, et al. Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2. J Mol Biol. 2021;434(2):167355doi: 10.1016/j.jmb.2021.167355.
Meissner, M. E., Willkomm, N. A., Lucas, J., Arndt, W. G., Aitken, S. F., Julik, E. J., Baliga, S., & Mansky, L. M. (2021). Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2. Journal of molecular biology, 434(2), 167355. https://doi.org/10.1016/j.jmb.2021.167355
Meissner, Morgan E, et al. "Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2." Journal of molecular biology vol. 434,2 (2021): 167355. doi: https://doi.org/10.1016/j.jmb.2021.167355
Meissner ME, Willkomm NA, Lucas J, Arndt WG, Aitken SF, Julik EJ, Baliga S, Mansky LM. Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2. J Mol Biol. 2021 Nov 10;434(2):167355. doi: 10.1016/j.jmb.2021.167355. Epub 2021 Nov 10. PMID: 34774569.
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Medial Column Support in Pilon Fractures Using Percutaneous Intramedullary Large Fragment Fixation.

Journal of orthopaedic trauma

Goodnough LH, Tigchelaar SS, Van Rysselberghe NL, DeBaun MR, Gardner MJ, Hecht GG, Lucas JF.
PMID: 33675625
J Orthop Trauma. 2021 Dec 01;35(12):e502-e506. doi: 10.1097/BOT.0000000000002073.

SUMMARY: Pilon fractures are complex injuries to the tibial plafond requiring stable fixation in the setting of effective soft tissue management, particularly in high-energy injuries, open fractures, or in geriatric individuals. Medial column support of the distal tibial metaphysis...

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Goodnough LH, Tigchelaar SS, Van Rysselberghe NL, et al. Medial Column Support in Pilon Fractures Using Percutaneous Intramedullary Large Fragment Fixation. J Orthop Trauma. 2021;35(12):e502-e506doi: 10.1097/BOT.0000000000002073.
Goodnough, L. H., Tigchelaar, S. S., Van Rysselberghe, N. L., DeBaun, M. R., Gardner, M. J., Hecht, G. G., & Lucas, J. F. (2021). Medial Column Support in Pilon Fractures Using Percutaneous Intramedullary Large Fragment Fixation. Journal of orthopaedic trauma, 35(12), e502-e506. https://doi.org/10.1097/BOT.0000000000002073
Goodnough, L Henry, et al. "Medial Column Support in Pilon Fractures Using Percutaneous Intramedullary Large Fragment Fixation." Journal of orthopaedic trauma vol. 35,12 (2021): e502-e506. doi: https://doi.org/10.1097/BOT.0000000000002073
Goodnough LH, Tigchelaar SS, Van Rysselberghe NL, DeBaun MR, Gardner MJ, Hecht GG, Lucas JF. Medial Column Support in Pilon Fractures Using Percutaneous Intramedullary Large Fragment Fixation. J Orthop Trauma. 2021 Dec 01;35(12):e502-e506. doi: 10.1097/BOT.0000000000002073. PMID: 33675625.
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Diverse alterations associated with resistance to KRAS(G12C) inhibition.

Nature

Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P.
PMID: 34759319
Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10.

Inactive state-selective KRAS(G12C) inhibitors

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Zhao Y, Murciano-Goroff YR, Xue JY, et al. Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021;599(7886):679-683doi: 10.1038/s41586-021-04065-2.
Zhao, Y., Murciano-Goroff, Y. R., Xue, J. Y., Ang, A., Lucas, J., Mai, T. T., Da Cruz Paula, A. F., Saiki, A. Y., Mohn, D., Achanta, P., Sisk, A. E., Arora, K. S., Roy, R. S., Kim, D., Li, C., Lim, L. P., Li, M., Bahr, A., Loomis, B. R., de Stanchina, E., Reis-Filho, J. S., Weigelt, B., Berger, M., Riely, G., Arbour, K. C., Lipford, J. R., Li, B. T., & Lito, P. (2021). Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature, 599(7886), 679-683. https://doi.org/10.1038/s41586-021-04065-2
Zhao, Yulei, et al. "Diverse alterations associated with resistance to KRAS(G12C) inhibition." Nature vol. 599,7886 (2021): 679-683. doi: https://doi.org/10.1038/s41586-021-04065-2
Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P. Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10. PMID: 34759319.
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Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise.

Medicine and science in sports and exercise

Lee JB, Notay K, Seed JD, Nardone M, Omazic LJ, Millar PJ.
PMID: 34310499
Med Sci Sports Exerc. 2021 Dec 01;53(12):2596-2604. doi: 10.1249/MSS.0000000000002747.

PURPOSE: Larger blood pressure (BP) responses to relative-intensity static exercise in men versus women are thought to involve altered muscle metaboreflex activation, but whether this is because of an intrinsic sex difference in metabolite production or differences in muscle...

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Lee JB, Notay K, Seed JD, et al. Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise. Med Sci Sports Exerc. 2021;53(12):2596-2604doi: 10.1249/MSS.0000000000002747.
Lee, J. B., Notay, K., Seed, J. D., Nardone, M., Omazic, L. J., & Millar, P. J. (2021). Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise. Medicine and science in sports and exercise, 53(12), 2596-2604. https://doi.org/10.1249/MSS.0000000000002747
Lee, Jordan B, et al. "Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise." Medicine and science in sports and exercise vol. 53,12 (2021): 2596-2604. doi: https://doi.org/10.1249/MSS.0000000000002747
Lee JB, Notay K, Seed JD, Nardone M, Omazic LJ, Millar PJ. Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise. Med Sci Sports Exerc. 2021 Dec 01;53(12):2596-2604. doi: 10.1249/MSS.0000000000002747. PMID: 34310499.
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Diverse alterations associated with resistance to KRAS(G12C) inhibition.

Nature

Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P.
PMID: 34759319
Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10.

Inactive state-selective KRAS(G12C) inhibitors

Cite
Zhao Y, Murciano-Goroff YR, Xue JY, et al. Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021;599(7886):679-683doi: 10.1038/s41586-021-04065-2.
Zhao, Y., Murciano-Goroff, Y. R., Xue, J. Y., Ang, A., Lucas, J., Mai, T. T., Da Cruz Paula, A. F., Saiki, A. Y., Mohn, D., Achanta, P., Sisk, A. E., Arora, K. S., Roy, R. S., Kim, D., Li, C., Lim, L. P., Li, M., Bahr, A., Loomis, B. R., de Stanchina, E., Reis-Filho, J. S., Weigelt, B., Berger, M., Riely, G., Arbour, K. C., Lipford, J. R., Li, B. T., & Lito, P. (2021). Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature, 599(7886), 679-683. https://doi.org/10.1038/s41586-021-04065-2
Zhao, Yulei, et al. "Diverse alterations associated with resistance to KRAS(G12C) inhibition." Nature vol. 599,7886 (2021): 679-683. doi: https://doi.org/10.1038/s41586-021-04065-2
Zhao Y, Murciano-Goroff YR, Xue JY, Ang A, Lucas J, Mai TT, Da Cruz Paula AF, Saiki AY, Mohn D, Achanta P, Sisk AE, Arora KS, Roy RS, Kim D, Li C, Lim LP, Li M, Bahr A, Loomis BR, de Stanchina E, Reis-Filho JS, Weigelt B, Berger M, Riely G, Arbour KC, Lipford JR, Li BT, Lito P. Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021 Nov;599(7886):679-683. doi: 10.1038/s41586-021-04065-2. Epub 2021 Nov 10. PMID: 34759319.
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Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis.

PLoS pathogens

Girard A, Cooper A, Mabbott S, Bradley B, Asiala S, Jamieson L, Clucas C, Capewell P, Marchesi F, Gibbins MP, Hentzschel F, Marti M, Quintana JF, Garside P, Faulds K, MacLeod A, Graham D.
PMID: 34780575
PLoS Pathog. 2021 Nov 15;17(11):e1010060. doi: 10.1371/journal.ppat.1010060. eCollection 2021 Nov.

Human African Trypanosomiasis (HAT) has been responsible for several deadly epidemics throughout the 20th century, but a renewed commitment to disease control has significantly reduced new cases and motivated a target for the elimination of Trypanosoma brucei gambiense-HAT by...

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Girard A, Cooper A, Mabbott S, et al. Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLoS Pathog. 2021;17(11):e1010060doi: 10.1371/journal.ppat.1010060.
Girard, A., Cooper, A., Mabbott, S., Bradley, B., Asiala, S., Jamieson, L., Clucas, C., Capewell, P., Marchesi, F., Gibbins, M. P., Hentzschel, F., Marti, M., Quintana, J. F., Garside, P., Faulds, K., MacLeod, A., & Graham, D. (2021). Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLoS pathogens, 17(11), e1010060. https://doi.org/10.1371/journal.ppat.1010060
Girard, Alexandre, et al. "Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis." PLoS pathogens vol. 17,11 (2021): e1010060. doi: https://doi.org/10.1371/journal.ppat.1010060
Girard A, Cooper A, Mabbott S, Bradley B, Asiala S, Jamieson L, Clucas C, Capewell P, Marchesi F, Gibbins MP, Hentzschel F, Marti M, Quintana JF, Garside P, Faulds K, MacLeod A, Graham D. Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLoS Pathog. 2021 Nov 15;17(11):e1010060. doi: 10.1371/journal.ppat.1010060. eCollection 2021 Nov. PMID: 34780575; PMCID: PMC8629383.
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Hydrogen bond design principles.

Wiley interdisciplinary reviews. Computational molecular science

Karas LJ, Wu CH, Das R, Wu JI.
PMID: 33936251
Wiley Interdiscip Rev Comput Mol Sci. 2020 Nov-Dec;10(6). doi: 10.1002/wcms.1477. Epub 2020 May 16.

Hydrogen bonding principles are at the core of supramolecular design. This overview features a discussion relating molecular structure to hydrogen bond strengths, highlighting the following electronic effects on hydrogen bonding: electronegativity, steric effects, electrostatic effects, π-conjugation, and network cooperativity....

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Karas LJ, Wu CH, Das R, et al. Hydrogen bond design principles. Wiley Interdiscip Rev Comput Mol Sci. 2020;10(6)doi: 10.1002/wcms.1477.
Karas, L. J., Wu, C. H., Das, R., & Wu, J. I. (2020). Hydrogen bond design principles. Wiley interdisciplinary reviews. Computational molecular science, 10(6), . https://doi.org/10.1002/wcms.1477
Karas, Lucas J, et al. "Hydrogen bond design principles." Wiley interdisciplinary reviews. Computational molecular science vol. 10,6 (2020). doi: https://doi.org/10.1002/wcms.1477
Karas LJ, Wu CH, Das R, Wu JI. Hydrogen bond design principles. Wiley Interdiscip Rev Comput Mol Sci. 2020 Nov-Dec;10(6). doi: 10.1002/wcms.1477. Epub 2020 May 16. PMID: 33936251; PMCID: PMC8087110.
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Showing 601 to 607 of 607 entries