Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1633 to 1636 of 1636 entries
Sorted by: Best Match Show Resources per page
Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.

Circulation

Simon JN, Vrellaku B, Monterisi S, Chu SM, Rawlings N, Lomas O, Marchal GA, Waithe D, Syeda F, Gajendragadkar PR, Jayaram R, Sayeed R, Channon KM, Fabritz L, Swietach P, Zaccolo M, Eaton P, Casadei B.
PMID: 33185461
Circulation. 2021 Feb 02;143(5):449-465. doi: 10.1161/CIRCULATIONAHA.120.046761. Epub 2020 Nov 13.

BACKGROUND: Kinase oxidation is a critical signaling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, PKARIα (type-1 protein kinase A) can be reversibly oxidized, forming interprotein disulfide bonds in the holoenzyme complex....

Patient Awareness of CKD: A Systematic Review and Meta-analysis of Patient-Oriented Questions and Study Setting.

Kidney medicine

Chu CD, Chen MH, McCulloch CE, Powe NR, Estrella MM, Shlipak MG, Tuot DS.
PMID: 34401725
Kidney Med. 2021 Jun 01;3(4):576-585.e1. doi: 10.1016/j.xkme.2021.03.014. eCollection 2021.

RATIONALE & OBJECTIVE: Patient awareness of disease is the first step toward effective management and disease control. Awareness of chronic kidney disease (CKD) has consistently been shown to be low, but studies estimating patient awareness of CKD have used...

Seizure Severity and Treatment Response in Newborn Infants with Seizures Attributed to Intracranial Hemorrhage.

The Journal of pediatrics

Herzberg EM, Machie M, Glass HC, Shellhaas RA, Wusthoff CJ, Chang T, Abend NS, Chu CJ, Cilio MR, Bonifacio SL, Massey SL, McCulloch CE, Soul JS.
PMID: 34780777
J Pediatr. 2021 Nov 13; doi: 10.1016/j.jpeds.2021.11.012. Epub 2021 Nov 13.

OBJECTIVE: We sought to characterize intracranial hemorrhage (ICH) as a seizure etiology in infants born term and preterm. For infants born term, we sought to compare seizure severity and treatment response for multisite vs single-site ICH and hypoxic-ischemic encephalopathy...

Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort.

Neurology

Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA.
PMID: 34266919
Neurology. 2021 Jul 15; doi: 10.1212/WNL.0000000000012511. Epub 2021 Jul 15.

OBJECTIVE: Compare the effectiveness of initial treatment for infantile spasms.METHODS: The National Infantile Spasms Consortium prospectively followed children with new onset infantile spasms that began at age 2-24 months at 23 US centers (2012-2018). Freedom from treatment failure at...

Showing 1633 to 1636 of 1636 entries