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Showing 13 to 24 of 110 entries
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A scalable, clinically severe pig model for Duchenne muscular dystrophy.

Disease models & mechanisms

Stirm M, Fonteyne LM, Shashikadze B, Lindner M, Chirivi M, Lange A, Kaufhold C, Mayer C, Medugorac I, Kessler B, Kurome M, Zakhartchenko V, Hinrichs A, Kemter E, Krause S, Wanke R, Arnold GJ, Wess G, Nagashima H, Hrabĕ de Angelis M, Flenkenthaler F, Kobelke LA, Bearzi C, Rizzi R, Bähr A, Reese S, Matiasek K, Walter MC, Kupatt C, Ziegler S, Bartenstein P, Fröhlich T, Klymiuk N, Blutke A, Wolf E.
PMID: 34796900
Dis Model Mech. 2021 Dec 01;14(12). doi: 10.1242/dmm.049285. Epub 2021 Dec 16.

Large-animal models for Duchenne muscular dystrophy (DMD) are crucial for the evaluation of diagnostic procedures and treatment strategies. Pigs cloned from male cells lacking DMD exon 52 (DMDΔ52) exhibit molecular, clinical and pathological hallmarks of DMD, but die before...

Enrichment of Glial Cells From Human Post-mortem Tissue for Transcriptome and Proteome Analysis Using Immunopanning.

Frontiers in cellular neuroscience

Nolle A, van Dijken I, Waelti CM, Calini D, Bryois J, Lezan E, Golling S, Augustin A, Foo L, Hoozemans JJM.
PMID: 34966261
Front Cell Neurosci. 2021 Dec 13;15:772011. doi: 10.3389/fncel.2021.772011. eCollection 2021.

Glia cells have a crucial role in the central nervous system and are involved in the majority of neurological diseases. While glia isolation techniques are well established for rodent brain, only recent advances in isolating glial cells from human...

High-grade astrocytoma with piloid features (HGAP): the Charité experience with a new central nervous system tumor entity.

Journal of neuro-oncology

Bender K, Perez E, Chirica M, Onken J, Kahn J, Brenner W, Ehret F, Euskirchen P, Koch A, Capper D, Kaul D.
PMID: 33905054
J Neurooncol. 2021 May;153(1):109-120. doi: 10.1007/s11060-021-03749-z. Epub 2021 Apr 27.

PURPOSE: High-grade astrocytoma with piloid features (HGAP) is a recently described brain tumor entity defined by a specific DNA methylation profile. HGAP has been proposed to be integrated in the upcoming World Health Organization classification of central nervous system...

Extra-articular involvement of rheumatoid arthritis in three seropositive patients in the absence of initial joint involvement.

Immunity, inflammation and disease

Chirila RM, Berianu F, Abril A, Butendieck RR.
PMID: 34473908
Immun Inflamm Dis. 2021 Dec;9(4):1613-1617. doi: 10.1002/iid3.514. Epub 2021 Sep 02.

INTRODUCTION: Extra-articular involvement (EAI) in rheumatoid arthritis (RA) is rare, severe and usually presents after years of joint involvement. Onset of RA as lung involvement has been published. We describe a series of three patients with strongly positive anti-citrullinated...

Sigma 1 Receptor is Overexpressed in Hepatocellular Adenoma: Involvement of ERα and HNF1α.

Cancers

Villemain L, Prigent S, Abou-Lovergne A, Pelletier L, Chiral M, Pontoglio M, Foufelle F, Caruso S, Pineau R, Rebouissou S, Chevet E, Zucman-Rossi J, Combettes L.
PMID: 32784704
Cancers (Basel). 2020 Aug 07;12(8). doi: 10.3390/cancers12082213.

Sigma receptor 1 (SigR1) is an endoplasmic reticulum resident integral membrane protein whose functions remain unclear. Although the liver shows the highest expression of SigR1, its role in this organ is unknown. SigR1 is overexpressed in many cancers and...

Assessing treatment response after intravesical bacillus Calmette-Guerin induction cycle: are routine bladder biopsies necessary?.

World journal of urology

Calò B, Sanguedolce F, Falagario UG, Chirico M, Fortunato F, Carvalho-Diaz E, Busetto GM, Bettocchi C, Carrieri G, Cormio L.
PMID: 33830306
World J Urol. 2021 Oct;39(10):3815-3821. doi: 10.1007/s00345-021-03690-w. Epub 2021 Apr 08.

PURPOSE: To determine the need for routine bladder biopsies (BBs) in assessing response to the induction cycle of intravesical bacillus Calmette-Guérin (BCG) for high-risk non-muscle-invasive bladder cancer (NMIBC).METHODS: Our prospectively maintained NMIBC database was queried to identify patients with...

Influence of Thickness on the Magnetic and Magnetotransport Properties of Epitaxial La.

Nanomaterials (Basel, Switzerland)

Greculeasa SG, Stanciu AE, Leca A, Kuncser A, Hrib L, Chirila C, Pasuk I, Kuncser V.
PMID: 34947736
Nanomaterials (Basel). 2021 Dec 14;11(12). doi: 10.3390/nano11123389.

Epitaxial La

Romanian Guidelines for Nonpharmacological Therapy of IBS.

Journal of gastrointestinal and liver diseases : JGLD

Dumitrascu DL, Baban A, Bancila I, Barboi O, Bataga S, Chira A, Chirila I, Cijevschi Prelipcean C, Ciobanu L, Cozma-Petrut A, David L, Diculescu M, Dobru D, Dimitriu A, Dumitru E, Fadgyas-Stanculete M, Gheorghe C, Gilca-Blanariu GE, Goldis A, Grad S, Macarie M, Marica-Sabo C, Miere D, Nedelcu L, Negovan A, Pojoga C, Pop AV, Popa SL, Porr PJ, Rusu F, Seicean A, Sporea I, Stroie T, Blaga-Surdea T, Tocia C, Trifan A, Brisc C, Drug V.
PMID: 33951120
J Gastrointestin Liver Dis. 2021 Jun 18;30(2):291-306. doi: 10.15403/jgld-3581.

BACKGROUND AND AIMS: The nonpharmacological therapy in irritable bowel syndrome (IBS) is expanding rapidly. Practitioners and medical educators need to be aware of progress and changes in knowledge of this topic. The Romanian Society of Neurogastroenterology aimed to create...

Transthyretin cardiac amyloidosis.

Medicine and pharmacy reports

Tomoaia R, Beyer R, Manole S, Chirilă A, Dădârlat-Pop A, Minciună IA, Pop D.
PMID: 34527900
Med Pharm Rep. 2021 Aug;94:S11-S14. doi: 10.15386/mpr-2219. Epub 2021 Aug 10.

Transthyretin amyloid cardiomyopathy (ATTR-CM) may be an under recognized cause of heart failure (HF). TTR amyloidosis can be inherited, caused by variants in the TTR gene (ATTRv) or by deposition of wild-type TTR protein (ATTRwt), leading to high mortality...

Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review).

Experimental and therapeutic medicine

Bărboi OB, Ciortescu I, Chirilă I, Anton C, Drug V.
PMID: 33101475
Exp Ther Med. 2020 Dec;20(6):185. doi: 10.3892/etm.2020.9315. Epub 2020 Oct 13.

At present, irritable bowel syndrome (IBS) is a common medical problem all over the world that implies considerable social burden and high costs. Considering the different pathophysiological pathways, unitary management for IBS is not possible. Of the therapeutic approaches...

Efficacy of Natural Formulations in Bovine Mastitis Pathology: Alternative Solution to Antibiotic Treatment.

Journal of veterinary research

Pașca C, Mărghitaș LA, Dezmirean DS, Matei IA, Bonta V, Pașca I, Chirilă F, Cîmpean A, Iosif Fiț N.
PMID: 33367141
J Vet Res. 2020 Oct 20;64(4):523-529. doi: 10.2478/jvetres-2020-0067. eCollection 2020 Dec.

INTRODUCTION: Bovine mastitis is an inflammatory disease of the udder that causes important economic losses in the animal breeding and dairy product industries. Nowadays, the conventional livestock antibiotic treatments are slowly being replaced by alternative treatments. In this context,...

[The combination treatment of arterial hypertension].

Viata medicala; revista de informare profesionala si stiintifica a cadrelor medii sanitare

Menek G, Gegö K, Tréfás I, Nagy I, Chiriac M.
PMID: 6812280
Viata Med Rev Inf Prof Stiint Cadrelor Medii Sanit. 1982 Jan;30(1):5-6.

No abstract available.

Showing 13 to 24 of 110 entries