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Showing 457 to 468 of 468 entries
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Opioids and Breast Cancer Recurrence: A Systematic Review.

Cancers

Lucia M, Luca T, Federica DP, Cecilia G, Chiara M, Laura M, Carlo DR, Grazia PM.
PMID: 34771662
Cancers (Basel). 2021 Nov 01;13(21). doi: 10.3390/cancers13215499.

Breast cancer has the greatest epidemiological impact in women. Opioids represent the most prescribed analgesics, both in surgical time and in immediate postoperative period, as well as in chronic pain management as palliative care. We made a systematic review...

The endocannabinoidome in neuropsychiatry: Opportunities and potential risks.

Pharmacological research

Morris G, Walder K, Kloiber S, Amminger P, Berk M, Bortolasci CC, Maes M, Puri BK, Carvalho AF.
PMID: 34119623
Pharmacol Res. 2021 Aug;170:105729. doi: 10.1016/j.phrs.2021.105729. Epub 2021 Jun 11.

The endocannabinoid system (ECS) comprises two cognate endocannabinoid receptors referred to as CB1R and CB2R

Short-Term Efficacy and Safety Outcomes of Brolucizumab in the Real-Life Clinical Practice.

Frontiers in pharmacology

Montesel A, Bucolo C, Sallo FB, Eandi CM.
PMID: 34803674
Front Pharmacol. 2021 Nov 04;12:720345. doi: 10.3389/fphar.2021.720345. eCollection 2021.

To report the early efficacy and safety outcomes of treatment with intravitreal injections of brolucizumab (IVT-B) in patients presenting neovascular age-related macular degeneration (nAMD) in a tertiary clinical setting. A retrospective case series of patients that received IVT-B with...

Effectiveness of Pre-Hospital Tourniquet in Emergency Patients with Major Trauma and Uncontrolled Haemorrhage: A Systematic Review and Meta-Analysis.

International journal of environmental research and public health

Latina R, Iacorossi L, Fauci AJ, Biffi A, Castellini G, Coclite D, D'Angelo D, Gianola S, Mari V, Napoletano A, Porcu G, Ruggeri M, Iannone P, Chiara O, On Behalf Of Inih-Major Trauma.
PMID: 34886586
Int J Environ Res Public Health. 2021 Dec 06;18(23). doi: 10.3390/ijerph182312861.

Trauma is one of the leading causes of uncontrolled haemorrhage, death, and disability. Use of a tourniquet can be considered an optimal anti-haemorrhagic resource, in pre-hospital and emergency settings, and its lifesaving effect is clinically contradictory. This review aims...

Cosmogenic radionuclides reveal an extreme solar particle storm near a solar minimum 9125 years BP.

Nature communications

Paleari CI, Mekhaldi F, Adolphi F, Christl M, Vockenhuber C, Gautschi P, Beer J, Brehm N, Erhardt T, Synal HA, Wacker L, Wilhelms F, Muscheler R.
PMID: 35017519
Nat Commun. 2022 Jan 11;13(1):214. doi: 10.1038/s41467-021-27891-4.

During solar storms, the Sun expels large amounts of energetic particles (SEP) that can react with the Earth's atmospheric constituents and produce cosmogenic radionuclides such as

Erratum to 'How we treat primary central nervous system lymphoma': [ESMO Open Volume 6, Issue 4, August 2021, 100213].

ESMO open

Calimeri T, Steffanoni S, Gagliardi F, Chiara A, Ferreri AJM.
PMID: 34773905
ESMO Open. 2021 Nov 10;6(6):100326. doi: 10.1016/j.esmoop.2021.100326. Epub 2021 Nov 10.

No abstract available.

Domain Wall Dynamics in a Ferroelastic Spin Crossover Complex with Giant Magnetoelectric Coupling.

Journal of the American Chemical Society

Jakobsen VB, Trzop E, Dobbelaar E, Gavin LC, Chikara S, Ding X, Lee M, Esien K, Müller-Bunz H, Felton S, Collet E, Carpenter MA, Zapf VS, Morgan GG.
PMID: 34939802
J Am Chem Soc. 2022 Jan 12;144(1):195-211. doi: 10.1021/jacs.1c08214. Epub 2021 Dec 23.

Pinned and mobile ferroelastic domain walls are detected in response to mechanical stress in a Mn

The Male Reproductive System and Endocrine Disruptors.

Endocrine, metabolic & immune disorders drug targets

Giovanni SM, Letizia AAM, Chiara M, Vincenzo S, Erika P, Marta S.
PMID: 34607552
Endocr Metab Immune Disord Drug Targets. 2021 Oct 03; doi: 10.2174/1871530321666211004100633. Epub 2021 Oct 03.

The male reproductive system is exposed to a great number of chemical substances which can interfere with the normal hormonal milieu and reproductive function; these are called endocrine disruptors (EDs). Despite a growing number of studies evaluating the negative...

A Novel Regimen for Treating Melanoma: MCL1 Inhibitors and Azacitidine.

Pharmaceuticals (Basel, Switzerland)

Dart CR, Mukherjee N, Amato CM, Goulding A, MacBeth M, Van Gulick R, Couts KL, Lambert JR, Norris DA, Robinson WA, Shellman YG.
PMID: 34451846
Pharmaceuticals (Basel). 2021 Jul 30;14(8). doi: 10.3390/ph14080749.

Although treatment options for melanoma patients have expanded in recent years with the approval of immunotherapy and targeted therapy, there is still an unmet need for new treatment options for patients that are ineligible for, or resistant to these...

Complete vertebrate mitogenomes reveal widespread repeats and gene duplications.

Genome biology

Formenti G, Rhie A, Balacco J, Haase B, Mountcastle J, Fedrigo O, Brown S, Capodiferro MR, Al-Ajli FO, Ambrosini R, Houde P, Koren S, Oliver K, Smith M, Skelton J, Betteridge E, Dolucan J, Corton C, Bista I, Torrance J, Tracey A, Wood J, Uliano-Silva M, Howe K, McCarthy S, Winkler S, Kwak W, Korlach J, Fungtammasan A, Fordham D, Costa V, Mayes S, Chiara M, Horner DS, Myers E, Durbin R, Achilli A, Braun EL, Phillippy AM, Jarvis ED.
PMID: 33910595
Genome Biol. 2021 Apr 29;22(1):120. doi: 10.1186/s13059-021-02336-9.

BACKGROUND: Modern sequencing technologies should make the assembly of the relatively small mitochondrial genomes an easy undertaking. However, few tools exist that address mitochondrial assembly directly.RESULTS: As part of the Vertebrate Genomes Project (VGP) we develop mitoVGP, a fully...

Search for Low-Mass Axion Dark Matter with ABRACADABRA-10 cm.

Physical review letters

Salemi CP, Foster JW, Ouellet JL, Gavin A, Pappas KMW, Cheng S, Richardson KA, Henning R, Kahn Y, Nguyen R, Rodd NL, Safdi BR, Winslow L.
PMID: 34477408
Phys Rev Lett. 2021 Aug 20;127(8):081801. doi: 10.1103/PhysRevLett.127.081801.

Two of the most pressing questions in physics are the microscopic nature of the dark matter that comprises 84% of the mass in the Universe and the absence of a neutron electric dipole moment. These questions would be resolved...

What if the future of HER2-positive breast cancer patients was written in miRNAs? An exploratory analysis from NeoALTTO study.

Cancer medicine

Pizzamiglio S, Cosentino G, Ciniselli CM, De Cecco L, Cataldo A, Plantamura I, Triulzi T, El-Abed S, Wang Y, Bajji M, Nuciforo P, Huober J, Ellard SL, Rimm DL, Gombos A, Daidone MG, Verderio P, Tagliabue E, Di Cosimo S, Iorio MV.
PMID: 34921525
Cancer Med. 2022 Jan;11(2):332-339. doi: 10.1002/cam4.4449. Epub 2021 Dec 17.

BACKGROUND: Neoadjuvant therapy with dual HER2 blockade improved pathological complete response (pCR) rate in HER2-positive breast cancer patients. Nevertheless, it would be desirable to identify patients exquisitely responsive to single agent trastuzumab to minimize or avoid overtreatment. Herein, we...

Showing 457 to 468 of 468 entries