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Showing 9985 to 9996 of 10024 entries
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Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer's disease: a focused review on recent advances.

Journal of neurology, neurosurgery, and psychiatry

Chong JR, Ashton NJ, Karikari TK, Tanaka T, Schöll M, Zetterberg H, Blennow K, Chen CP, Lai MKP.
PMID: 34510001
J Neurol Neurosurg Psychiatry. 2021 Nov;92(11):1231-1241. doi: 10.1136/jnnp-2021-327370. Epub 2021 Sep 11.

Discovery and development of clinically useful biomarkers for Alzheimer's disease (AD) and related dementias have been the focus of recent research efforts. While cerebrospinal fluid and positron emission tomography or MRI-based neuroimaging markers have made the in vivo detection...

Assessing the Potential Earthquake Precursory Information in ULF Magnetic Data Recorded in Kanto, Japan during 2000-2010: Distance and Magnitude Dependences.

Entropy (Basel, Switzerland)

Han P, Zhuang J, Hattori K, Chen CH, Febriani F, Chen H, Yoshino C, Yoshida S.
PMID: 33286630
Entropy (Basel). 2020 Aug 01;22(8). doi: 10.3390/e22080859.

In order to clarify ultra-low-frequency (ULF) seismomagnetic phenomena, a sensitive geomagnetic network was installed in Kanto, Japan since 2000. In previous studies, we have verified the correlation between ULF magnetic anomalies and local sizeable earthquakes. In this study, we...

Student-Authored Scientist Spotlights: Investigating the Impacts of Engaging Undergraduates as Developers of Inclusive Curriculum through a Service-Learning Course.

CBE life sciences education

Aranda ML, Diaz M, Mena LG, Ortiz JI, Rivera-Nolan C, Sanchez DC, Sanchez MJ, Upchurch AM, Williams CS, Boorstin SN, Cardoso LM, Dominguez M, Elias S, Lopez EE, Ramirez RE, Romero PJ, Tigress FN, Wilson JA, Winstead R, Cantley JT, Chen JC, Fuse M, Goldman MA, Govindan B, Ingmire P, Knight JD, Pasion SG, Pennings PS, Sehgal RNM, de Vera PT, Kelley L, Schinske JN, Riggs B, Burrus LW, Tanner KD.
PMID: 34546103
CBE Life Sci Educ. 2021 Dec;20(4):ar55. doi: 10.1187/cbe.21-03-0060.

Scientist Spotlights-curricular materials that employ the personal and professional stories of scientists from diverse backgrounds-have previously been shown to positively influence undergraduate students' relatability to and perceptions of scientists. We hypothesized that engaging students in authoring Scientist Spotlights might...

Improved Blend Film Morphology and Free Carrier Generation Provide a High-Performance Ternary Polymer Solar Cell.

ACS applied materials & interfaces

Jiang BH, Wang YP, Liao CY, Chang YM, Su YW, Jeng RJ, Chen CP.
PMID: 33356102
ACS Appl Mater Interfaces. 2021 Jan 13;13(1):1076-1085. doi: 10.1021/acsami.0c19198. Epub 2020 Dec 23.

Non-fullerene organic photovoltaics (OPVs) have displayed the highest power conversion efficiencies (PCEs) among OPVs. Herein, we describe a two-donor (PM6, TPD-3F)/one-acceptor (Y6) ternary blend having an optimized blend morphology that leads to improved OPV performance. Because TPD-3F has a...

Anti-Food Allergic Alkaloids from the Lotus Seed Pot.

Chemistry & biodiversity

Cao TW, Xie CL, Chen CQ, He ZH, Yan QX, Xu G, Yang XW.
PMID: 34664390
Chem Biodivers. 2021 Dec;18(12):e2100770. doi: 10.1002/cbdv.202100770. Epub 2021 Nov 10.

Lotus seed pod (LSP) has been used as traditional herbal cuisine to modulate immunity. From the AcOEt-soluble extract of LSP, one new aporphine alkaloid, N-[2-(2H-phenanthro[3,4-d][1,3]dioxol-5-yl)ethyl]acetamide (nelunucine A, 1) was obtained along with 19 known ones. Their structures were established...

Primary care staff's willingness to participate in compassionate community network and palliative care and the barriers they face: a mixed methods study.

BMJ open

Chang HT, Lin MH, Kuo WH, Chen CK, Chen TJ, Hwang SJ.
PMID: 34548345
BMJ Open. 2021 Sep 21;11(9):e046961. doi: 10.1136/bmjopen-2020-046961.

OBJECTIVES: Compassionate community models, successfully applied in several Western countries, have not been extensively promoted in Asian countries. This study explored primary care staff's willingness to participate and factors associated with their participations in compassionate community education and network,...

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

NPJ breast cancer

El Bairi K, Haynes HR, Blackley E, Fineberg S, Shear J, Turner S, de Freitas JR, Sur D, Amendola LC, Gharib M, Kallala A, Arun I, Azmoudeh-Ardalan F, Fujimoto L, Sua LF, Liu SW, Lien HC, Kirtani P, Balancin M, El Attar H, Guleria P, Yang W, Shash E, Chen IC, Bautista V, Do Prado Moura JF, Rapoport BL, Castaneda C, Spengler E, Acosta-Haab G, Frahm I, Sanchez J, Castillo M, Bouchmaa N, Md Zin RR, Shui R, Onyuma T, Yang W, Husain Z, Willard-Gallo K, Coosemans A, Perez EA, Provenzano E, Ericsson PG, Richardet E, Mehrotra R, Sarancone S, Ehinger A, Rimm DL, Bartlett JMS, Viale G, Denkert C, Hida AI, Sotiriou C, Loibl S, Hewitt SM, Badve S, Symmans WF, Kim RS, Pruneri G, Goel S, Francis PA, Inurrigarro G, Yamaguchi R, Garcia-Rivello H, Horlings H, Afqir S, Salgado R, Adams S, Kok M, Dieci MV, Michiels S, Demaria S, Loi S.
PMID: 34853355
NPJ Breast Cancer. 2021 Dec 01;7(1):150. doi: 10.1038/s41523-021-00346-1.

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed death-ligand 1 (PD-L1). These patients...

Corrigendum: Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney.

Frontiers in physiology

Dalmasso C, Chade AR, Mendez M, Giani JF, Bix GJ, Chen KC, Loria AS.
PMID: 33329067
Front Physiol. 2020 Nov 16;11:615022. doi: 10.3389/fphys.2020.615022. eCollection 2020.

[This corrects the article DOI: 10.3389/fphys.2020.01046.].

Investigation of solvent microparticle formation in spray ionization-quadrupole ion trap-mass spectrometry.

Journal of mass spectrometry : JMS

Özdemir A, Lin JL, Gülfen M, Chen CH.
PMID: 34607391
J Mass Spectrom. 2021 Nov;56(11):e4785. doi: 10.1002/jms.4785.

In the present study, a new method has been developed for the real-time analysis of insource created solvent particles based on spray ionization-quadrupole ion trap-mass spectrometry (SI-QIT-MS). This is the first work in the literature reporting the formation of...

A user-friendly objective prediction model in predicting colorectal cancer based on 234 044 Asian adults in a prospective cohort.

ESMO open

Chen CH, Tsai MK, Wen C, Wen CP.
PMID: 34808523
ESMO Open. 2021 Dec;6(6):100288. doi: 10.1016/j.esmoop.2021.100288. Epub 2021 Nov 20.

BACKGROUND: Prediction models of colorectal cancer (CRC) had limited application for not being user-friendly. Whether fecal immunochemical tests (FITs) can help predict CRC has been overlooked.PATIENTS AND METHODS: With 1972 CRCs identified, 234 044 adults aged ≥40 years were...

Improving Algorithm for the Alignment of Consecutive, Whole-Slide, Immunohistochemical Section Images.

Journal of pathology informatics

Liang CW, Chang RF, Fang PW, Chen CM.
PMID: 34476109
J Pathol Inform. 2021 Aug 03;12:29. doi: 10.4103/jpi.jpi_106_20. eCollection 2021.

BACKGROUND: Accurate and precise alignment of histopathology tissue sections is a key step for the interpretation of the proteome topology and cell level three-dimensional (3D) reconstruction of diseased tissues. However, the realization of an automated and robust method for...

Healthcare utilization and psychiatric and physical comorbidities before suicide mortality in patients with methamphetamine use disorder: A nationwide case-control study.

Addictive behaviors

Lee WC, Chang HM, Huang MC, Pan CH, Su SS, Tsai SY, Chen CC, Kuo CJ.
PMID: 34839069
Addict Behav. 2021 Nov 24;126:107192. doi: 10.1016/j.addbeh.2021.107192. Epub 2021 Nov 24.

BACKGROUND: Since the late 1990s, methamphetamine use has become a considerable public health concern. Despite high suicide rates among methamphetamine users, studies exploring medical utilization and psychiatric and physical comorbidities before suicide are scant. We aim to examine the...

Showing 9985 to 9996 of 10024 entries