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Showing 1693 to 1700 of 1700 entries
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Hydroxysafflor yellow A and anhydrosafflor yellow B alleviate ferroptosis and parthanatos in PC12 cells injured by OGD/R.

Free radical biology & medicine

Chen G, Li C, Zhang L, Yang J, Meng H, Wan H, He Y.
PMID: 34923102
Free Radic Biol Med. 2021 Dec 16;179:1-10. doi: 10.1016/j.freeradbiomed.2021.12.262. Epub 2021 Dec 16.

Ferroptosis and parthanatos are two types of programmed cell death associated with cerebral ischemia. There is a sizeable interest in seeking chemical components for the regulation of ferroptosis and parthanatos. Hydroxysafflor yellow A (HSYA) and anhydrosafflor yellow B (AHSYB)...

Clinical Significance of Frailty on Treatment Outcome in Nongeriatric Patients With Head and Neck Cancer and Esophageal Cancer Undergoing Curative-Intent Concurrent Chemoradiotherapy.

Cancer control : journal of the Moffitt Cancer Center

Chou WC, Lai CC, Hung CY, Hsueh SW, Yeh KY, Lu CH, Tsang NM, Chang PH, Ho YW, Chen SY, Lin YC, Hung YS.
PMID: 34994207
Cancer Control. 2022 Jan-Dec;29:10732748211045276. doi: 10.1177/10732748211045276.

BACKGROUND: Whether the prevalence of frailty and its clinical significance are relevant to treatment outcomes in younger (aged < 65 years) cancer patients remains uncertain. This study aimed to evaluate the impact of frailty on treatment outcomes in younger...

The Effect of Statins in Cancer Risk Reduction in Patients on Dialysis: A Population-Based Case-Control Study.

Journal of clinical medicine

Chen PH, Jhou HJ, Chung CH, Lee CH, Wu YY, Chang WC, Chien WC, Chang PY.
PMID: 34884304
J Clin Med. 2021 Nov 28;10(23). doi: 10.3390/jcm10235602.

BACKGROUND: To realize whether statins reduce the risk of cancer in susceptible dialysis populations, this study analyzed the relationship between statin use and cancer risk in patients on dialysis.METHODS: Patients having a history of chronic kidney disease with hemodialysis...

Measuring the impact of burn injury on the parent-reported health outcomes of children 1-to-5 years: Item pool development for the Preschool.

Burns : journal of the International Society for Burn Injuries

Grant GG, Brady KJS, Stoddard FJ, Meyer WJ, Romanowski KS, Chang PH, Painting LE, Fowler LA, Nelson JK, Patel KF, Sheldrick RC, Carter A, Sheridan RL, Slavin MD, Warner P, Palmieri TL, Schneider JC, Kazis LE, Ryan CM.
PMID: 33832799
Burns. 2021 Nov;47(7):1511-1524. doi: 10.1016/j.burns.2021.02.010. Epub 2021 Feb 25.

Modern, reliable, and valid outcome measures are essential to understanding the health needs of young children with burn injuries. Burn-specific and age-appropriate legacy assessment tools exist for this population but are hindered by the limitations of existing paper-based instruments....

Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design.

European journal of medicinal chemistry

Yeh TK, Song JS, Chang PW, Yu JC, Chang CH, Liao FY, Tien YW, Kuppusamy R, Li AS, Chen CH, Chen CW, Lin LM, Chang HH, Huang CH, Yao JY, Wu MH, Peng YH, Hsueh CC, Hsiao WC, Chen PH, Lin CY, Hsieh SH, Shih C, Hung MS, Wu SY, Kuo CC, Ueng SH.
PMID: 34929581
Eur J Med Chem. 2021 Dec 08;229:114043. doi: 10.1016/j.ejmech.2021.114043. Epub 2021 Dec 08.

Indoleamine 2,3-dioxygenase-1 (IDO1) is a potential target for the next generation of cancer immunotherapies. We describe the development of two series of IDO1 inhibitors incorporating a N-hydroxy-thiophene-carboximidamide core generated by knowledge-based drug design. Structural modifications to improve the cellular...

Clinical Significance of Frailty on Treatment Outcome in Nongeriatric Patients With Head and Neck Cancer and Esophageal Cancer Undergoing Curative-Intent Concurrent Chemoradiotherapy.

Cancer control : journal of the Moffitt Cancer Center

Chou WC, Lai CC, Hung CY, Hsueh SW, Yeh KY, Lu CH, Tsang NM, Chang PH, Ho YW, Chen SY, Lin YC, Hung YS.
PMID: 34994207
Cancer Control. 2022 Jan-Dec;29:10732748211045276. doi: 10.1177/10732748211045276.

BACKGROUND: Whether the prevalence of frailty and its clinical significance are relevant to treatment outcomes in younger (aged < 65 years) cancer patients remains uncertain. This study aimed to evaluate the impact of frailty on treatment outcomes in younger...

Effect of Tantalum Pentoxide Addition on the Radiopacity Performance of Bi.

Materials (Basel, Switzerland)

Lin HN, Lin CK, Chang PJ, Chang WM, Fang A, Chen CY, Yu CC, Lee PY.
PMID: 34885606
Materials (Basel). 2021 Dec 04;14(23). doi: 10.3390/ma14237447.

Among the various phases of bismuth oxide, the high temperature metastable face-centered cubic δ phase attracts great attention due to its unique properties. It can be used as an ionic conductor or an endodontic radiopacifying material. However, no reports...

Physics achievements from the Belle experiment.

Brodzicka J, Browder T, Chang P, Eidelman S, Golob B, Hayasaka K, Hayashii H, Iijima T, Inami K, Kinoshita K, Kwon Y, Miyabayashi K, Mohanty G, Nakao M, Nakazawa H, Olsen S, Sakai Y, Schwanda C, Schwartz A, Trabelsi K, Uehara S, Uno S, Watanabe Y, Zupanc A, Belle Collaboration.
UIID-AD: 359
2012; doi: 10.1093/ptep/pts072.

The Belle experiment, running at the KEKB e(+)e(-) asymmetric energy collider during the first decade of the century, achieved its original objective of precisely measuring differences between particles and antiparticles in the B system. After collecting 1000 fb(-1) of...

Showing 1693 to 1700 of 1700 entries